Strain Name:
C57BL/6J-MtgxR3110Btlr/Mmmh
Stock Number:
040584-MU
Citation ID:
RRID:MMRRC_040584-MU
Other Names:
R3110 (G1), C57BL/6J-MtgxR3110Btlr
Major Collection:

Gene Information

Jarid2
Name: jumonji, AT rich interactive domain 2
Synonyms: Jmj, jumonji
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 16468
HGNC: HGNC:6196
Homologene: 31279
Orc1
Name: origin recognition complex, subunit 1
Synonyms: MmORC1, Orc1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 18392
HGNC: HGNC:8487
Homologene: 31221
Jmjd1c
Name: jumonji domain containing 1C
Synonyms: TRIP8, 5430433L24Rik, D630035I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 108829
Homologene: 3129
Mybl1
Name: myeloblastosis oncogene-like 1
Synonyms: repro9, G1-419-6, A-myb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 17864
HGNC: HGNC:7547
Homologene: 32045
Scrib
Name: scribbled planar cell polarity
Synonyms: Crc, Scrb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 105782
Homologene: 44228
Dock5
Name: dedicator of cytokinesis 5
Synonyms: rlc, 1110060D06Rik, lr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 68813
VEGA: 14
Homologene: 57016
Wee1
Name: WEE 1 homolog 1 (S. pombe)
Synonyms: Wee1A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22390
Homologene: 31152
Slc4a2
Name: solute carrier family 4 (anion exchanger), member 2
Synonyms: B3RP, Ae2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 20535
Homologene: 128699
Uaca
Name: uveal autoantigen with coiled-coil domains and ankyrin repeats
Synonyms: 2700059D02Rik, nucling
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 72565
VEGA: 9
Homologene: 74297
Gpat4
Name: glycerol-3-phosphate acyltransferase 4
Synonyms: Agpat6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 102247
Homologene: 32425
Rsf1
Name: remodeling and spacing factor 1
Synonyms: XAP8, p325, 4832420A03Rik, C030033M12Rik, Hbxap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233532
Homologene: 41142
Nup37
Name: nucleoporin 37
Synonyms: 2810039M17Rik, 2410003L22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 69736
VEGA: 10
Homologene: 11441
Fntb
Name: farnesyltransferase, CAAX box, beta
Synonyms: 2010013E13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 110606
HGNC: HGNC:3785
Homologene: 1535
Ccdc141
Name: coiled-coil domain containing 141
Synonyms: 2610301F02Rik, CAMDI, ENSMUSG00000075261
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 545428
Homologene: 52149
Lrrk2
Name: leucine-rich repeat kinase 2
Synonyms: cI-46, 4921513O20Rik, D630001M17Rik, 9330188B09Rik, LOC381026
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 66725
Homologene: 18982
Sppl3
Name: signal peptide peptidase 3
Synonyms: Usmg3, 4833416I09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 74585
Homologene: 15563
Gpx7
Name: glutathione peroxidase 7
Synonyms: GPX6, 3110050F08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 67305
HGNC: HGNC:4559
Homologene: 128491
Cdc7
Name: cell division cycle 7 (S. cerevisiae)
Synonyms: Cdc7l1, Cdc7, muCdc7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 12545
HGNC: HGNC:1745
Homologene: 31166
Ttc13
Name: tetratricopeptide repeat domain 13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234875
Homologene: 11569
Ebf1
Name: early B cell factor 1
Synonyms: O/E-1, Olf-1, Olf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 13591
HGNC: HGNC:3126
Homologene: 7297
Grn
Name: granulin
Synonyms: progranulin, epithelin, PC cell-derived growth factor, Pgrn, acrogranulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14824
HGNC: HGNC:4601
Homologene: 1577
Adam15
Name: a disintegrin and metallopeptidase domain 15 (metargidin)
Synonyms: metargidin, MDC15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 11490
HGNC: HGNC:193
Homologene: 2829
Pigo
Name: phosphatidylinositol glycan anchor biosynthesis, class O
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 56703
Homologene: 31761
Atp1a3
Name: ATPase, Na+/K+ transporting, alpha 3 polypeptide
Synonyms: Atpa-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 232975
HGNC: HGNC:801
Homologene: 113729
Nlrp9a
Name: NLR family, pyrin domain containing 9A
Synonyms: D7Ertd565e, Nalp9a, Nalp-theta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233001
Homologene: 116072
Fam135b
Name: family with sequence similarity 135, member B
Synonyms: A830008O07Rik, 1700010C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 70363
VEGA: 15
Homologene: 66605
Tnn
Name: tenascin N
Synonyms: Tnw, tenascin-W
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 329278
Homologene: 18634
Iigp1
Name: interferon inducible GTPase 1
Synonyms: 2900074L10Rik, Irga6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 60440
VEGA: 18
Acer1
Name: alkaline ceramidase 1
Synonyms: Cer1, 2310024P18Rik, Asah3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 171168
VEGA: 17
Homologene: 15853
Ccdc180
Name: coiled-coil domain containing 180
Synonyms: LOC381522, E230008N13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 381522
Homologene: 117988
Olfr1338
Name: olfactory receptor 1338
Synonyms: MOR259-4P, Olfr1524-ps1, MOR259-9, GA_x6K02T2QD9B-18795136-18796077, MOR259-4P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 258259
Homologene: 115537
Lipe
Name: lipase, hormone sensitive
Synonyms: HSL, 4933403G17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 16890
HGNC: HGNC:6621
Homologene: 3912
Btn1a1
Name: butyrophilin, subfamily 1, member A1
Synonyms: Btn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 12231
HGNC: HGNC:1135
Homologene: 1312
Abca6
Name: ATP-binding cassette, sub-family A (ABC1), member 6
Synonyms: 6330565N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 76184
HGNC: HGNC:36
Homologene: 71264
Syce1l
Name: synaptonemal complex central element protein 1 like
Synonyms: mmrp2, 4930481F22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 668110
Homologene: 86343
Cpb1
Name: carboxypeptidase B1 (tissue)
Synonyms: 0910001A18Rik, 2210008M23Rik, 1810063F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 76703
HGNC: HGNC:2299
Homologene: 68127
Speg
Name: SPEG complex locus
Synonyms: Apeg1, SPEGalpha, SPEG, BPEG, SPEGbeta, D1Bwg1450e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 11790
Homologene: 55619
Psg23
Name: pregnancy-specific glycoprotein 23
Synonyms: 1620401C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 56868
Homologene: 110989
Plekhh3
Name: pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217198
Homologene: 11787
Ncln
Name: nicalin
Synonyms: 3100002P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 103425
Homologene: 10604
Gm14139
Name: predicted gene 14139
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 100271882
Homologene: 134546
Trim5
Name: tripartite motif-containing 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 667823
Homologene: 75345
Fpr1
Name: formyl peptide receptor 1
Synonyms: fMLF-R, FPR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 14293
HGNC: HGNC:3826
Homologene: 20466
Hmgxb3
Name: HMG box domain containing 3
Synonyms: 2510002C16Rik, A630042L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 106894
VEGA: 18
Homologene: 44229
Ankrd13b
Name: ankyrin repeat domain 13b
Synonyms: B930093C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 268445
Homologene: 27367
Plch1
Name: phospholipase C, eta 1
Synonyms: Plcl3, PLCeta1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 269437
Homologene: 88833
Usp16
Name: ubiquitin specific peptidase 16
Synonyms: 6330514E22Rik, 2810483I07Rik, UBP-M, 1200004E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 74112
Homologene: 38183
Pramel5
Name: preferentially expressed antigen in melanoma like 5
Synonyms: OTTMUSG00000010540
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 384077
Homologene: 133722
Acads
Name: acyl-Coenzyme A dehydrogenase, short chain
Synonyms: Hdlq8, Bcd-1, SCAD, Bcd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 11409
HGNC: HGNC:90
Homologene: 20057
Gm9932
Name: predicted gene 9932
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
Mlc1
Name: megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)
Synonyms: Kiaa0027-hp, WKL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 170790
Homologene: 15775
Zfp786
Name: zinc finger protein 786
Synonyms: A730012O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 330301
Homologene: 51849
Fxyd1
Name: FXYD domain-containing ion transport regulator 1
Synonyms: 1110006M24Rik, 0610012C17Rik, PML, PLM, phospholemman
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 56188
HGNC: HGNC:4025
Homologene: 3691
Fam57a
Name: family with sequence similarity 57, member A
Synonyms: 2310047D13Rik, 5430420K21Rik, 4932415L08Rik, 5430402E13Rik, Wdt3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 116972
Homologene: 11720
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 9,681,870 bp
  • C to T, chromosome 1 at 75,422,682 bp
  • T to A, chromosome 1 at 160,116,286 bp
  • C to T, chromosome 2 at 77,039,486 bp
  • C to G, chromosome 2 at 150,192,221 bp
  • C to T, chromosome 3 at 20,265,357 bp
  • T to A, chromosome 3 at 63,709,531 bp
  • C to G, chromosome 3 at 89,347,457 bp
  • T to C, chromosome 4 at 43,021,083 bp
  • T to A, chromosome 4 at 45,900,470 bp
  • C to A, chromosome 4 at 108,403,273 bp
  • T to A, chromosome 4 at 108,604,560 bp
  • A to T, chromosome 4 at 118,754,224 bp
  • A to G, chromosome 4 at 144,273,858 bp
  • T to A, chromosome 5 at 24,435,026 bp
  • A to T, chromosome 5 at 100,198,935 bp
  • T to G, chromosome 5 at 106,974,698 bp
  • A to T, chromosome 5 at 115,074,864 bp
  • T to C, chromosome 5 at 115,117,698 bp
  • A to G, chromosome 6 at 47,820,226 bp
  • T to C, chromosome 7 at 18,610,444 bp
  • T to C, chromosome 7 at 24,994,694 bp
  • T to C, chromosome 7 at 25,398,423 bp
  • T to C, chromosome 7 at 26,557,872 bp
  • A to T, chromosome 7 at 31,053,010 bp
  • ATGGCG to ATGGCGACGGTGGCG, chromosome 7 at 97,579,904 bp
  • T to C, chromosome 7 at 104,279,638 bp
  • T to A, chromosome 7 at 110,130,836 bp
  • G to A, chromosome 8 at 23,180,155 bp
  • A to G, chromosome 8 at 113,654,947 bp
  • A to G, chromosome 8 at 124,683,834 bp
  • A to G, chromosome 9 at 60,871,499 bp
  • T to A, chromosome 10 at 67,240,084 bp
  • C to T, chromosome 10 at 81,487,685 bp
  • T to A, chromosome 10 at 88,153,515 bp
  • T to A, chromosome 11 at 44,643,398 bp
  • A to G, chromosome 11 at 76,202,231 bp
  • A to G, chromosome 11 at 77,477,505 bp
  • T to C, chromosome 11 at 101,164,147 bp
  • A to G, chromosome 11 at 102,433,243 bp
  • T to A, chromosome 11 at 110,178,829 bp
  • C to A, chromosome 12 at 76,910,353 bp
  • T to A, chromosome 13 at 23,461,551 bp
  • T to A, chromosome 13 at 44,906,276 bp
  • A to G, chromosome 14 at 67,857,922 bp
  • T to C, chromosome 15 at 71,464,030 bp
  • A to T, chromosome 15 at 76,069,374 bp
  • A to T, chromosome 15 at 88,965,996 bp
  • A to G, chromosome 15 at 91,814,695 bp
  • T to A, chromosome 16 at 87,471,848 bp
  • A to T, chromosome 17 at 17,876,635 bp
  • G to A, chromosome 17 at 56,958,406 bp
  • T to C, chromosome 18 at 60,390,911 bp
  • T to C, chromosome 18 at 61,147,382 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3110 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040584-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.