Strain Name:
C57BL/6J-MtgxR3429Btlr/Mmmh
Stock Number:
040647-MU
Citation ID:
RRID:MMRRC_040647-MU
Other Names:
R3429 (G1), C57BL/6J-MtgxR3429Btlr
Major Collection:

Gene Information

Fgg
Name: fibrinogen gamma chain
Synonyms: gamma-fibrinogen, 3010002H13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 99571
HGNC: HGNC:3694
Homologene: 429
Dgat2
Name: diacylglycerol O-acyltransferase 2
Synonyms: 0610010B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67800
Homologene: 23580
Nfib
Name: nuclear factor I/B
Synonyms: 6720429L07Rik, E030026I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18028
HGNC: HGNC:7785
Homologene: 4087
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Pam, C130061D10Rik, Phr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105689
Homologene: 9005
Rlf
Name: rearranged L-myc fusion sequence
Synonyms: 9230110M18Rik, MommeD8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 109263
Homologene: 8243
Ctage5
Name: CTAGE family, member 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Usp25
Name: ubiquitin specific peptidase 25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 30940
VEGA: 16
Homologene: 8374
Zfr
Name: zinc finger RNA binding protein
Synonyms: C920030H05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 22763
Homologene: 8009
Zfp106
Name: zinc finger protein 106
Synonyms: Cd-1, H3a, sirm, Sh3bp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20402
Homologene: 40787
Ankfy1
Name: ankyrin repeat and FYVE domain containing 1
Synonyms: Ankhzn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11736
Homologene: 9491
Zfp26
Name: zinc finger protein 26
Synonyms: mkr-3, Zfp-26, 5033428C05Rik, Zfp70, KRAB15, Zfp81-rs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 22688
Homologene: 52318
Rif1
Name: replication timing regulatory factor 1
Synonyms: 5730435J01Rik, 6530403D07Rik, D2Ertd145e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 51869
Homologene: 41231
Gstz1
Name: glutathione transferase zeta 1 (maleylacetoacetate isomerase)
Synonyms: maleylacetoacetate isomerase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 14874
VEGA: 12
HGNC: HGNC:4643
Homologene: 7747
Myo1d
Name: myosin ID
Synonyms: 9930104H07Rik, D11Ertd9e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 338367
HGNC: HGNC:7598
Homologene: 45576
Prkcq
Name: protein kinase C, theta
Synonyms: PKC-0, Pkcq, A130035A12Rik, PKC-theta, PKC theta, PKCtheta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18761
HGNC: HGNC:9410
Homologene: 21263
Hs3st3a1
Name: heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
Synonyms: 3Ost3a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 15478
HGNC: HGNC:5196
Homologene: 88735
Lrrtm3
Name: leucine rich repeat transmembrane neuronal 3
Synonyms: 9630044H04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216028
Homologene: 37110
Cntrl
Name: centriolin
Synonyms: IB3/5, 6720467O09Rik, Ma2a8, Cep1, b2b1468Clo, Cep110
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 26920
HGNC: HGNC:1858
Homologene: 38260
Sost
Name: sclerostin
Synonyms: 5430411E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74499
Homologene: 11542
Tsku
Name: tsukushi, small leucine rich proteoglycan
Synonyms: 9530051K01Rik, Lrrc54
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244152
Homologene: 41045
Eps8l2
Name: EPS8-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 98845
Homologene: 69358
Abca16
Name: ATP-binding cassette, sub-family A (ABC1), member 16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233810
Homologene: 132942
Pnp
Name: purine-nucleoside phosphorylase
Synonyms: Np-2, Np-1, Np, Pnp, Pnp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 18950
HGNC: HGNC:7892
Homologene: 227
Bhmt
Name: betaine-homocysteine methyltransferase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 12116
HGNC: HGNC:1047
Homologene: 1295
Hmcn2
Name: hemicentin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 665700
Homologene: 90772
Dnah6
Name: dynein, axonemal, heavy chain 6
Synonyms: A730004I20Rik, Dnahc6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330355
HGNC: HGNC:2951
Homologene: 15221
Dchs1
Name: dachsous cadherin related 1
Synonyms: C130033F22Rik, 3110041P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233651
Homologene: 2771
Tet3
Name: tet methylcytosine dioxygenase 3
Synonyms: D230004J03Rik, B430006D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 194388
Homologene: 35360
Col12a1
Name: collagen, type XII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12816
HGNC: HGNC:2188
Homologene: 3217
Scn7a
Name: sodium channel, voltage-gated, type VII, alpha
Synonyms: Nav2.3, NaG, Nav2, 1110034K09Rik, Scn6a, Nax
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20272
Homologene: 55706
Cyp2c66
Name: cytochrome P450, family 2, subfamily c, polypeptide 66
Synonyms: 2010301M18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 69888
Homologene: 133566
Cdh5
Name: cadherin 5
Synonyms: VE-cadherin, 7B4/cadherin-5, VEC, CD144, VE-Cad, VECD, VEcad
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12562
HGNC: HGNC:1764
Homologene: 1359
Sybu
Name: syntabulin (syntaxin-interacting)
Synonyms: A830027B17Rik, Golsyn/Syntabulin, 5730410E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 319613
VEGA: 15
Homologene: 9838
Lonp1
Name: lon peptidase 1, mitochondrial
Synonyms: LON, 1200017E13Rik, Prss15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 74142
VEGA: 17
HGNC: HGNC:9479
Homologene: 3521
Clca3a2
Name: chloride channel accessory 3A2
Synonyms: Clca2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 80797
Homologene: 77224
A2m
Name: alpha-2-macroglobulin
Synonyms: A2mp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232345
HGNC: HGNC:7
Homologene: 37248
Col6a6
Name: collagen, type VI, alpha 6
Synonyms: E330026B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 245026
Homologene: 18260
Tnxb
Name: tenascin XB
Synonyms: Tnx, TN-MHC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 81877
Homologene: 49589
Parp3
Name: poly (ADP-ribose) polymerase family, member 3
Synonyms: Adprt3, PARP-3, A930002C11Rik, Adprtl3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235587
HGNC: HGNC:273
Homologene: 4005
Acad11
Name: acyl-Coenzyme A dehydrogenase family, member 11
Synonyms: 5730439E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 102632
Homologene: 49896
Aoc1
Name: amine oxidase, copper-containing 1
Synonyms: 1600012D06Rik, Abp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 76507
HGNC: HGNC:80
Homologene: 68159
Filip1
Name: filamin A interacting protein 1
Synonyms: 5730485H21Rik, FILIP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 70598
Homologene: 6700
Afap1l2
Name: actin filament associated protein 1-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226250
Homologene: 13057
Fut1
Name: fucosyltransferase 1
Synonyms: H transferase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 14343
HGNC: HGNC:4012
Homologene: 120
Lmntd2
Name: lamin tail domain containing 2
Synonyms: 1600016N20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 72000
Homologene: 104159
Cpeb2
Name: cytoplasmic polyadenylation element binding protein 2
Synonyms: A630055H10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231207
Homologene: 17995
Or4c29
Name: olfactory receptor family 4 subfamily C member 29
Synonyms: GA_x6K02T2Q125-50386882-50385950, MOR230-7, Olfr1209
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258453
Homologene: 128155
Vmn1r215
Name: vomeronasal 1 receptor 215
Synonyms: V1ri2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 171253
Homologene: 110880
Sgce
Name: sarcoglycan, epsilon
Synonyms: e-SG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 20392
Homologene: 31205
Tas1r2
Name: taste receptor, type 1, member 2
Synonyms: TR2, T1r2, Gpr71
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 83770
Homologene: 75323
Or2y1e
Name: olfactory receptor family 2 subfamily Y member 1E
Synonyms: GA_x6K02T2QP88-6107233-6106298, MOR256-27, Olfr1391
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258460
Homologene: 17264
AC133939.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
B4galnt4
Name: beta-1,4-N-acetyl-galactosaminyl transferase 4
Synonyms: LOC381951
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 330671
Homologene: 27982
E430018J23Rik
Name: RIKEN cDNA E430018J23 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101604
Homologene: 138471
Asah1
Name: N-acylsphingosine amidohydrolase 1
Synonyms: acid ceramidase, 2310081N20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11886
HGNC: HGNC:735
Homologene: 10504
Or2ak5
Name: olfactory receptor family 2 subfamily AK member 5
Synonyms: GA_x6K02T2NKPP-692816-693736, MOR285-1, Olfr318
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258494
Homologene: 133825
Foxl2
Name: forkhead box L2
Synonyms: Pfrk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 26927
HGNC: HGNC:1092
Homologene: 74992
Or2b7
Name: olfactory receptor family 2 subfamily B member 7
Synonyms: MOR256-36, GA_x6K02T2QHY8-11688984-11689964, MOR256-36, MOR256-63, Olfr1365, Olfr1535
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 404335
Homologene: 131356
Sh3d21
Name: SH3 domain containing 21
Synonyms: 1700029G01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66938
Homologene: 12057
Or4c121
Name: olfactory receptor family 4 subfamily C member 121
Synonyms: GA_x6K02T2Q125-50672630-50671698, MOR233-2, Olfr1226
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258969
Homologene: 27315
Hacd1
Name: 3-hydroxyacyl-CoA dehydratase 1
Synonyms: Ptpla
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 30963
HGNC: HGNC:9639
Homologene: 69153
Gm10323
Name: predicted gene 10323
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105245545
VEGA: 13
Krtap1-4
Name: keratin associated protein 1-4
Synonyms: OTTMUSG00000004966
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 629873
Homologene: 87892
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 2 at 11,246,970 bp
  • T to C, chromosome 2 at 14,044,775 bp
  • T to A, chromosome 2 at 31,409,144 bp
  • T to C, chromosome 2 at 35,145,100 bp
  • GCCACCA to GCCA, chromosome 2 at 52,110,324 bp
  • AT to ATT, chromosome 2 at 66,700,895 bp
  • C to T, chromosome 2 at 88,909,466 bp
  • T to A, chromosome 2 at 89,193,273 bp
  • T to C, chromosome 2 at 120,527,063 bp
  • T to A, chromosome 3 at 83,012,783 bp
  • T to A, chromosome 3 at 144,806,327 bp
  • T to C, chromosome 4 at 82,498,295 bp
  • A to G, chromosome 4 at 121,150,532 bp
  • A to G, chromosome 4 at 126,162,832 bp
  • A to G, chromosome 4 at 139,669,575 bp
  • T to A, chromosome 5 at 7,180,625 bp
  • T to C, chromosome 5 at 43,281,230 bp
  • T to A, chromosome 6 at 4,730,008 bp
  • A to T, chromosome 6 at 48,906,076 bp
  • G to A, chromosome 6 at 73,121,814 bp
  • A to G, chromosome 6 at 83,403,419 bp
  • T to A, chromosome 6 at 121,636,290 bp
  • T to C, chromosome 7 at 45,619,374 bp
  • T to C, chromosome 7 at 98,352,539 bp
  • A to G, chromosome 7 at 99,157,093 bp
  • A to G, chromosome 7 at 105,756,504 bp
  • T to C, chromosome 7 at 120,543,982 bp
  • T to C, chromosome 7 at 127,391,742 bp
  • T to C, chromosome 7 at 141,070,839 bp
  • A to G, chromosome 7 at 141,213,997 bp
  • G to A, chromosome 7 at 141,357,919 bp
  • C to T, chromosome 8 at 41,351,888 bp
  • T to A, chromosome 8 at 104,130,968 bp
  • A to G, chromosome 9 at 20,441,460 bp
  • T to A, chromosome 9 at 79,680,311 bp
  • A to T, chromosome 9 at 79,853,670 bp
  • T to C, chromosome 9 at 98,955,982 bp
  • A to G, chromosome 9 at 104,081,832 bp
  • A to T, chromosome 9 at 105,777,967 bp
  • A to T, chromosome 9 at 106,474,723 bp
  • G to A, chromosome 10 at 63,930,272 bp
  • C to T, chromosome 11 at 49,328,041 bp
  • T to A, chromosome 11 at 58,720,271 bp
  • C to T, chromosome 11 at 64,436,322 bp
  • C to T, chromosome 11 at 72,712,154 bp
  • C to T, chromosome 11 at 80,682,410 bp
  • G to C, chromosome 11 at 99,583,194 bp
  • C to G, chromosome 11 at 101,964,039 bp
  • A to G, chromosome 12 at 59,189,641 bp
  • T to A, chromosome 12 at 87,163,696 bp
  • A to T, chromosome 13 at 21,555,805 bp
  • T to A, chromosome 13 at 23,076,208 bp
  • A to C, chromosome 13 at 66,854,824 bp
  • T to C, chromosome 13 at 93,627,347 bp
  • A to G, chromosome 14 at 50,947,986 bp
  • A to T, chromosome 14 at 103,229,430 bp
  • T to C, chromosome 15 at 12,152,920 bp
  • T to C, chromosome 15 at 44,746,458 bp
  • C to T, chromosome 16 at 77,069,138 bp
  • C to A, chromosome 17 at 34,672,631 bp
  • A to G, chromosome 17 at 34,703,587 bp
  • T to A, chromosome 17 at 56,618,337 bp
  • T to A, chromosome 19 at 39,163,448 bp
  • C to A, chromosome 19 at 56,915,806 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3429 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040647-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.