Strain Name:
C57BL/6J-MtgxR3432Btlr/Mmmh
Stock Number:
040650-MU
Citation ID:
RRID:MMRRC_040650-MU
Other Names:
R3432 (G1), C57BL/6J-MtgxR3432Btlr
Major Collection:

Gene Information

Evl
Name: Ena-vasodilator stimulated phosphoprotein
Synonyms: b2b2600Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 14026
VEGA: 12
Homologene: 56752
Lpp
Name: LIM domain containing preferred translocation partner in lipoma
Synonyms: 9430020K16Rik, B130055L10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 210126
VEGA: 16
HGNC: HGNC:6679
Homologene: 4075
Zfp407
Name: zinc finger protein 407
Synonyms: 6430585N13Rik, LOC240469, LOC381139
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240476
Homologene: 86402
Mcm2
Name: minichromosome maintenance complex component 2
Synonyms: BM28, CDCL1, Mcmd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 17216
HGNC: HGNC:6944
Homologene: 3325
Efs
Name: embryonal Fyn-associated substrate
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 13644
VEGA: 14
Homologene: 4284
Erc1
Name: ELKS/RAB6-interacting/CAST family member 1
Synonyms: Elks1, RAB6IP2A, RAB6IP2B, B430107L16Rik, 9630025C19Rik, Rab6ip2, 5033405M01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 111173
Homologene: 14229
Rbm15
Name: RNA binding motif protein 15
Synonyms: C230088J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229700
Homologene: 23383
Angptl2
Name: angiopoietin-like 2
Synonyms: Arp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 26360
HGNC: HGNC:490
Homologene: 22695
Tbc1d19
Name: TBC1 domain family, member 19
Synonyms: 2810453K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 67249
Homologene: 10130
Actr3
Name: ARP3 actin-related protein 3
Synonyms: Arp3, 1200003A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74117
HGNC: HGNC:170
Homologene: 68483
Slc15a4
Name: solute carrier family 15, member 4
Synonyms: PTR4, C130069N12Rik, PHT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100561
Homologene: 26432
Uggt1
Name: UDP-glucose glycoprotein glucosyltransferase 1
Synonyms: C820010P03Rik, Ugcgl1, A930007H10Rik, 0910001L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 320011
Homologene: 10586
Cmtr1
Name: cap methyltransferase 1
Synonyms: Ftsjd2, 1300018I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 74157
Homologene: 9003
Pitpnm1
Name: phosphatidylinositol transfer protein, membrane-associated 1
Synonyms: RdgB, DRES9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18739
HGNC: HGNC:9003
Homologene: 3608
Taf5
Name: TATA-box binding protein associated factor 5
Synonyms: 6330528C20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226182
VEGA: 19
Homologene: 5064
Trim58
Name: tripartite motif-containing 58
Synonyms: LOC216781, LOC386443
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216781
Homologene: 9135
Olfr983
Name: olfactory receptor 983
Synonyms: MOR162-1, GA_x6K02T2PVTD-33790948-33790013
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258824
VEGA: 9
Homologene: 121547
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380698
Homologene: 70869
Adamts3
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3
Synonyms: 1100001H14Rik, 6330442E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 330119
HGNC: HGNC:219
Homologene: 8596
Man1a
Name: mannosidase 1, alpha
Synonyms: mannosyl-oligosaccharide alpha-1,2-mannosidase, PCR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 17155
HGNC: HGNC:6821
Homologene: 4316
Serpinb1a
Name: serine (or cysteine) peptidase inhibitor, clade B, member 1a
Synonyms: 1190005M04Rik, ELANH2, M/NEI, MNEI, EIA, ovalbumin, LEI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 66222
HGNC: HGNC:3311
Homologene: 133768
Mfsd13a
Name: major facilitator superfamily domain containing 13a
Synonyms: 4930449A08Rik, 4930538D17Rik, Tmem180
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 75146
Homologene: 12592
Ptprt
Name: protein tyrosine phosphatase, receptor type, T
Synonyms: RPTPrho
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19281
HGNC: HGNC:9682
Homologene: 56924
Hhipl1
Name: hedgehog interacting protein-like 1
Synonyms: 1600002O04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 214305
VEGA: 12
Homologene: 81985
Aoc1
Name: amine oxidase, copper-containing 1
Synonyms: Abp1, 1600012D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 76507
HGNC: HGNC:80
Homologene: 68159
Myo5c
Name: myosin VC
Synonyms: 9130003O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 208943
VEGA: 9
HGNC: HGNC:7604
Homologene: 135711
Glp1r
Name: glucagon-like peptide 1 receptor
Synonyms: GLP1Rc, GLP-1R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14652
VEGA: 17
HGNC: HGNC:4324
Homologene: 1558
Zdhhc23
Name: zinc finger, DHHC domain containing 23
Synonyms: LOC332175, LOC385651
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 332175
VEGA: 16
Homologene: 17840
Tssk4
Name: testis-specific serine kinase 4
Synonyms: 4933424F08Rik, 1700020B19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 71099
VEGA: 14
Homologene: 57078
Zfp872
Name: zinc finger protein 872
Synonyms: 9530015I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 619310
Sec14l5
Name: SEC14-like lipid binding 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 665119
VEGA: 16
Homologene: 96163
Sirpb1a
Name: signal-regulatory protein beta 1A
Synonyms: Sirpb1, 9930027N05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 320832
Homologene: 82993
Cpt1b
Name: carnitine palmitoyltransferase 1b, muscle
Synonyms: M-CPTI, Cpt1, M-CPT I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12895
HGNC: HGNC:2329
Homologene: 22548
Atp8b3
Name: ATPase, class I, type 8B, member 3
Synonyms: 1700056N23Rik, 1700042F02Rik, SAPLT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67331
VEGA: 10
Homologene: 19034
Psg18
Name: pregnancy specific glycoprotein 18
Synonyms: Cea3, mmCGM6, Cea-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 26438
Homologene: 110989
Ceacam5
Name: carcinoembryonic antigen-related cell adhesion molecule 5
Synonyms: Psg30, 1600029H12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 73250
Homologene: 115938
Il18r1
Name: interleukin 18 receptor 1
Synonyms: Il1rrp, Il18ralpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16182
HGNC: HGNC:5988
Homologene: 2861
Arsj
Name: arylsulfatase J
Synonyms: 9330196J05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 271970
Homologene: 35257
Rap2a
Name: RAS related protein 2a
Synonyms: 5830461H18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 76108
HGNC: HGNC:9861
Homologene: 10875
Bahd1
Name: bromo adjacent homology domain containing 1
Synonyms: LOC228536
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228536
Homologene: 8976
Fbxo16
Name: F-box protein 16
Synonyms: Fbx16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 50759
VEGA: 14
Homologene: 9273
Mmel1
Name: membrane metallo-endopeptidase-like 1
Synonyms: NEPLP gamma, Mell1, Nl1, SEP, NEPLP alpha, NEPLP beta, Nep2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 27390
Homologene: 22778
Dhrs7c
Name: dehydrogenase/reductase (SDR family) member 7C
Synonyms: 1110001P11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68460
Homologene: 19108
Hbq1a
Name: hemoglobin, theta 1A
Synonyms: Hbq1, LOC380691, A230090E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216635
HGNC: HGNC:4833
Fam89b
Name: family with sequence similarity 89, member B
Synonyms: 1110021A21Rik, Mtvr2, Fam89b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 17826
Homologene: 18749
Gstp1
Name: glutathione S-transferase, pi 1
Synonyms: Gst p-1, GstpiB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 14870
HGNC: HGNC:4638
Homologene: 660
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 36,210,059 bp
  • C to T, chromosome 1 at 40,487,089 bp
  • G to A, chromosome 1 at 125,394,039 bp
  • T to C, chromosome 2 at 33,228,802 bp
  • G to A, chromosome 2 at 118,922,523 bp
  • T to C, chromosome 2 at 161,927,529 bp
  • A to G, chromosome 3 at 15,426,387 bp
  • A to T, chromosome 3 at 107,330,677 bp
  • A to T, chromosome 3 at 126,364,975 bp
  • C to T, chromosome 4 at 154,885,498 bp
  • T to C, chromosome 5 at 53,848,206 bp
  • A to G, chromosome 5 at 89,707,453 bp
  • A to G, chromosome 5 at 127,604,536 bp
  • A to T, chromosome 6 at 48,905,844 bp
  • G to A, chromosome 6 at 88,893,008 bp
  • C to A, chromosome 6 at 119,783,475 bp
  • T to A, chromosome 7 at 17,714,976 bp
  • A to G, chromosome 7 at 18,349,171 bp
  • C to T, chromosome 9 at 22,200,454 bp
  • A to T, chromosome 9 at 40,092,549 bp
  • A to G, chromosome 9 at 75,263,001 bp
  • A to G, chromosome 10 at 53,920,274 bp
  • T to C, chromosome 10 at 80,526,180 bp
  • T to G, chromosome 11 at 32,300,715 bp
  • T to C, chromosome 11 at 58,646,961 bp
  • A to G, chromosome 11 at 59,031,177 bp
  • C to T, chromosome 11 at 67,809,873 bp
  • A to G, chromosome 12 at 108,311,689 bp
  • T to C, chromosome 12 at 108,648,308 bp
  • T to C, chromosome 13 at 32,842,859 bp
  • C to T, chromosome 14 at 54,920,224 bp
  • A to G, chromosome 14 at 55,651,695 bp
  • T to C, chromosome 14 at 65,293,784 bp
  • G to T, chromosome 14 at 120,503,758 bp
  • T to C, chromosome 15 at 89,423,741 bp
  • A to G, chromosome 16 at 5,178,599 bp
  • T to C, chromosome 16 at 24,889,886 bp
  • T to A, chromosome 16 at 43,974,170 bp
  • T to C, chromosome 17 at 29,687,027 bp
  • T to A, chromosome 17 at 30,924,557 bp
  • G to A, chromosome 18 at 84,208,746 bp
  • G to A, chromosome 19 at 4,036,695 bp
  • G to A, chromosome 19 at 4,111,710 bp
  • A to T, chromosome 19 at 5,731,733 bp
  • C to T, chromosome 19 at 46,371,992 bp
  • A to C, chromosome 19 at 47,075,833 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3432 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040650-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.