Strain Name:
C57BL/6J-MtgxR3737Btlr/Mmmh
Stock Number:
040724-MU
Citation ID:
RRID:MMRRC_040724-MU
Other Names:
R3737 (G1), C57BL/6J-MtgxR3737Btlr
Major Collection:

Gene Information

Myh9
Name: myosin, heavy polypeptide 9, non-muscle
Synonyms: myosin IIA, Myhn-1, NMHC II-A, E030044M24Rik, D0Jmb2, Fltn, Myhn1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 17886
HGNC: HGNC:7579
Homologene: 129835
Cdk17
Name: cyclin-dependent kinase 17
Synonyms: 6430598J10Rik, Pctk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237459
VEGA: 10
HGNC: HGNC:8750
Homologene: 55666
Zfa-ps
Name: zinc finger protein, autosomal, pseudogene
Synonyms: Zfa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 22639
Ifi203
Name: interferon activated gene 203
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 15950
HGNC: HGNC:5395
Homologene: 115929
Ccdc88c
Name: coiled-coil domain containing 88C
Synonyms: 0610010D24Rik, Daple
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 68339
VEGA: 12
Homologene: 18903
Utp20
Name: UTP20 small subunit processome component
Synonyms: DRIM, mDRIM, 3830408P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70683
VEGA: 10
Homologene: 38373
Trmo
Name: tRNA methyltransferase O
Synonyms: 5830415F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 74753
Homologene: 32316
Bicral
Name: BRD4 interacting chromatin remodeling complex associated protein like
Synonyms: BC032203, Gltscr1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 210982
VEGA: 17
Homologene: 19366
Zbtb7c
Name: zinc finger and BTB domain containing 7C
Synonyms: B230208J24Rik, Zbtb36, Kr-pok
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 207259
VEGA: 18
Homologene: 17070
Pcm1
Name: pericentriolar material 1
Synonyms: C030044G17Rik, 9430077F19Rik, 2600002H09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 18536
HGNC: HGNC:8727
Homologene: 4518
Hcn4
Name: hyperpolarization-activated, cyclic nucleotide-gated K+ 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 330953
VEGA: 9
Homologene: 3997
Prtg
Name: protogenin
Synonyms: A230098A12Rik, Igdcc5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235472
Homologene: 54453
Hmgcr
Name: 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
Synonyms: Red, 3-hydroxy-3-methylglutaryl-CoA reductase, HMG-CoAR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 15357
HGNC: HGNC:5006
Homologene: 30994
Ankrd11
Name: ankyrin repeat domain 11
Synonyms: 2410104C19Rik, 9530048I21Rik, 3010027A04Rik, Yod
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 77087
Homologene: 69134
Xrcc6
Name: X-ray repair complementing defective repair in Chinese hamster cells 6
Synonyms: G22p1, Ku70, Ku p70
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 14375
HGNC: HGNC:4055
Homologene: 37483
Api5
Name: apoptosis inhibitor 5
Synonyms: AAC-11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11800
HGNC: HGNC:594
Homologene: 4809
Dop1a
Name: DOP1 leucine zipper like protein A
Synonyms: B130005I07Rik, D9Ertd809e, Dopey1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320615
Homologene: 26645
Brd2
Name: bromodomain containing 2
Synonyms: Fsrg1, Ring3, Rnf3, D17H6S113E, Frg-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14312
HGNC: HGNC:1103
Homologene: 74540
Mon2
Name: MON2 homolog, regulator of endosome to Golgi trafficking
Synonyms: SF21, 2610528O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67074
VEGA: 10
Homologene: 44309
Ttk
Name: Ttk protein kinase
Synonyms: Mps1, Esk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 22137
Homologene: 2489
Kctd9
Name: potassium channel tetramerisation domain containing 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105440
Homologene: 9754
Osbpl2
Name: oxysterol binding protein-like 2
Synonyms: C130070J12Rik, ORP-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228983
Homologene: 77324
C6
Name: complement component 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12274
HGNC: HGNC:1339
Homologene: 47
Otud6b
Name: OTU domain containing 6B
Synonyms: 2600013N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 72201
Homologene: 6064
Ubr3
Name: ubiquitin protein ligase E3 component n-recognin 3
Synonyms: 4833421P10Rik, 1110059H15Rik, Zfp650, A130030D10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68795
Homologene: 52092
Srsf4
Name: serine and arginine-rich splicing factor 4
Synonyms: 5730499P16Rik, Sfrs4, SRp75, MNCb-2616
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 57317
Homologene: 25624
Isl2
Name: insulin related protein 2 (islet 2)
Synonyms: islet 2, 3110001N10Rik, islet-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 104360
Homologene: 10730
Il1f5
Name: interleukin 1 family, member 5 (delta)
Synonyms: IL-1H3, IL1F5, FIL1delta, IL1HY1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 54450
Homologene: 10453
Arap1
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
Synonyms: 2410002L19Rik, Centd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 69710
Homologene: 12326
Nolc1
Name: nucleolar and coiled-body phosphoprotein 1
Synonyms: P130, 3230402K17Rik, NOPP140
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 70769
VEGA: 19
Palld
Name: palladin, cytoskeletal associated protein
Synonyms: 2410003B16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 72333
Homologene: 75052
Usp42
Name: ubiquitin specific peptidase 42
Synonyms: D5Ertd591e, 2410140K03Rik, A630018G05Rik, 3110031A07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 76800
Homologene: 35425
Usp6nl
Name: USP6 N-terminal like
Synonyms: TRE2NL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 98910
Homologene: 6879
Lcorl
Name: ligand dependent nuclear receptor corepressor-like
Synonyms: Mlr1, A830039H10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 209707
Homologene: 82325
Ska3
Name: spindle and kinetochore associated complex subunit 3
Synonyms: F630043A04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219114
VEGA: 14
Homologene: 124284
Hmcn2
Name: hemicentin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 665700
Homologene: 90772
Dchs1
Name: dachsous cadherin related 1
Synonyms: C130033F22Rik, 3110041P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233651
Homologene: 2771
Taf5l
Name: TATA-box binding protein associated factor 5 like
Synonyms: 1110005N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 102162
Homologene: 8676
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: Dnahc9, D11Ertd686e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Mroh2b
Name: maestro heat-like repeat family member 2B
Synonyms: 4930455B06Rik, Heatr7b2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223825
VEGA: 15
Homologene: 128807
Tprgl
Name: transformation related protein 63 regulated like
Synonyms: mover, 1200015A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67808
Homologene: 12192
Gprc6a
Name: G protein-coupled receptor, family C, group 6, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 210198
VEGA: 10
Homologene: 17529
Serpinb6d
Name: serine (or cysteine) peptidase inhibitor, clade B, member 6d
Synonyms: SPI3D, Gm11390
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238568
HGNC: HGNC:8950
Adcy2
Name: adenylate cyclase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 210044
VEGA: 13
HGNC: HGNC:233
Homologene: 75133
Ltbp2
Name: latent transforming growth factor beta binding protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 16997
HGNC: HGNC:6715
Homologene: 369
Prg4
Name: proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
Synonyms: lubricin, SZP, DOL54, MSF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 96875
HGNC: HGNC:9364
Homologene: 137352
Gal3st2c
Name: galactose-3-O-sulfotransferase 2C
Synonyms: Gm6086
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 619597
Homologene: 41471
Pde6c
Name: phosphodiesterase 6C, cGMP specific, cone, alpha prime
Synonyms: cpfl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 110855
VEGA: 19
HGNC: HGNC:8787
Homologene: 4521
Mfsd2b
Name: major facilitator superfamily domain containing 2B
Synonyms: Gm1964
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 432628
Homologene: 47753
Clca3a1
Name: chloride channel accessory 3A1
Synonyms: Clca1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12722
Homologene: 77224
Ube2j1
Name: ubiquitin-conjugating enzyme E2J 1
Synonyms: Ncube, 0710008M05Rik, 1110030I22Rik, Ubc6p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56228
Homologene: 41090
Nlrp4f
Name: NLR family, pyrin domain containing 4F
Synonyms: Nalp-kappa, Nalp4f, C330026N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 97895
VEGA: 13
Homologene: 87252
Olfr878
Name: olfactory receptor 878
Synonyms: MOR163-1, GA_x6K02T2PVTD-31600511-31601440
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258794
HGNC: HGNC:8473
Homologene: 17395
Rap1b
Name: RAS related protein 1b
Synonyms: 2810443E11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215449
VEGA: 10
HGNC: HGNC:9857
Homologene: 68719
Usp49
Name: ubiquitin specific peptidase 49
Synonyms: C330046L10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224836
Homologene: 10235
Spesp1
Name: sperm equatorial segment protein 1
Synonyms: 4921508E09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 66712
VEGA: 9
Homologene: 49838
Ppl
Name: periplakin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19041
VEGA: 16
HGNC: HGNC:9273
Homologene: 2026
Fgfbp1
Name: fibroblast growth factor binding protein 1
Synonyms: FGF-BP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14181
Homologene: 3766
Vmn1r55
Name: vomeronasal 1 receptor 55
Synonyms: LOC384522, LOC236535, V1rd5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 384522
Homologene: 41799
R3hcc1
Name: R3H domain and coiled-coil containing 1
Synonyms: 1700020M16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 71843
Homologene: 136250
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 94,009,328 bp
  • T to A, chromosome 1 at 150,452,213 bp
  • T to A, chromosome 1 at 173,929,474 bp
  • C to A, chromosome 2 at 6,440,917 bp
  • T to C, chromosome 2 at 24,281,203 bp
  • A to T, chromosome 2 at 31,336,612 bp
  • G to A, chromosome 2 at 69,971,234 bp
  • C to T, chromosome 2 at 94,425,613 bp
  • G to A, chromosome 2 at 180,161,560 bp
  • A to G, chromosome 3 at 144,730,721 bp
  • A to G, chromosome 4 at 14,815,678 bp
  • A to T, chromosome 4 at 33,036,723 bp
  • C to T, chromosome 4 at 46,389,312 bp
  • C to T, chromosome 4 at 131,900,102 bp
  • T to C, chromosome 4 at 154,160,128 bp
  • T to C, chromosome 5 at 43,979,596 bp
  • A to T, chromosome 5 at 45,734,041 bp
  • C to T, chromosome 5 at 143,715,439 bp
  • T to G, chromosome 7 at 5,147,196 bp
  • A to T, chromosome 7 at 101,400,277 bp
  • T to A, chromosome 7 at 105,762,316 bp
  • T to A, chromosome 8 at 41,261,043 bp
  • G to T, chromosome 8 at 61,535,682 bp
  • A to G, chromosome 8 at 122,896,715 bp
  • T to C, chromosome 8 at 124,009,675 bp
  • G to A, chromosome 9 at 37,918,641 bp
  • A to G, chromosome 9 at 55,542,470 bp
  • A to G, chromosome 9 at 58,843,889 bp
  • T to A, chromosome 9 at 62,273,036 bp
  • G to T, chromosome 9 at 72,842,709 bp
  • C to A, chromosome 9 at 83,854,837 bp
  • T to C, chromosome 9 at 86,494,433 bp
  • A to C, chromosome 10 at 51,626,911 bp
  • T to A, chromosome 10 at 52,544,540 bp
  • C to T, chromosome 10 at 88,762,806 bp
  • G to A, chromosome 10 at 93,221,644 bp
  • G to A, chromosome 10 at 117,822,880 bp
  • A to G, chromosome 10 at 123,013,375 bp
  • G to A, chromosome 11 at 66,156,908 bp
  • A to G, chromosome 12 at 4,870,578 bp
  • A to T, chromosome 12 at 84,804,474 bp
  • G to A, chromosome 12 at 100,930,524 bp
  • T to A, chromosome 13 at 33,667,680 bp
  • T to C, chromosome 13 at 65,194,007 bp
  • A to T, chromosome 13 at 68,657,465 bp
  • C to G, chromosome 13 at 96,651,063 bp
  • A to T, chromosome 14 at 57,811,596 bp
  • G to A, chromosome 14 at 67,734,288 bp
  • C to T, chromosome 14 at 69,697,593 bp
  • T to C, chromosome 15 at 4,781,971 bp
  • T to C, chromosome 15 at 4,945,148 bp
  • G to A, chromosome 15 at 77,766,812 bp
  • T to C, chromosome 15 at 82,029,631 bp
  • T to C, chromosome 16 at 5,106,857 bp
  • A to G, chromosome 17 at 34,117,080 bp
  • A to T, chromosome 17 at 46,825,910 bp
  • G to A, chromosome 17 at 47,672,318 bp
  • T to G, chromosome 18 at 76,136,940 bp
  • T to A, chromosome 19 at 38,140,224 bp
  • CAG to CAGTAG, chromosome 19 at 46,081,353 bp
  • GCA to GCAACA, chromosome 19 at 46,081,370 bp
  • C to CAGT, chromosome 19 at 46,081,377 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3737 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040724-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.