Strain Name:
C57BL/6J-MtgxR3787Btlr/Mmmh
Stock Number:
040754-MU
Citation ID:
RRID:MMRRC_040754-MU
Other Names:
R3787 (G1), C57BL/6J-MtgxR3787Btlr
Major Collection:

Gene Information

Sall4
Name: spalt like transcription factor 4
Synonyms: 5730441M18Rik, C330011P20Rik, Tex20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99377
Homologene: 10716
Neurod1
Name: neurogenic differentiation 1
Synonyms: Neurod, BETA2, bHLHa3, Nd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18012
HGNC: HGNC:7762
Homologene: 1871
Thbs4
Name: thrombospondin 4
Synonyms: TSP4, TSP-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 21828
Homologene: 20691
Fancd2
Name: Fanconi anemia, complementation group D2
Synonyms: 2410150O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 211651
HGNC: HGNC:3585
Homologene: 13212
Pmepa1
Name: prostate transmembrane protein, androgen induced 1
Synonyms: STAG1, N4wbp4, Tmepai, 2210418I02Rik, PMEPA1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 65112
Homologene: 10608
Fryl
Name: FRY like transcription coactivator
Synonyms: 2310004H21Rik, 2510002A14Rik, 9030227G01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 72313
Homologene: 103956
Inpp5k
Name: inositol polyphosphate 5-phosphatase K
Synonyms: C62, putative PI-5-phosphatase, PI-5-phosphatase related, Pps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 19062
Homologene: 75059
Rfc1
Name: replication factor C (activator 1) 1
Synonyms: Recc1, RFC140, Alp145, 140kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19687
HGNC: HGNC:9969
Homologene: 2187
Exo1
Name: exonuclease 1
Synonyms: Msa, 5730442G03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 26909
HGNC: HGNC:3511
Homologene: 31352
Heatr1
Name: HEAT repeat containing 1
Synonyms: B130016L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 217995
VEGA: 13
Homologene: 34562
Dmxl1
Name: Dmx-like 1
Synonyms: C630007L23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240283
HGNC: HGNC:2937
Homologene: 21136
Bptf
Name: bromodomain PHD finger transcription factor
Synonyms: 9430093H17Rik, Falz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 207165
HGNC: HGNC:3581
Homologene: 114397
Mki67
Name: antigen identified by monoclonal antibody Ki 67
Synonyms: Ki67, Ki-67, D630048A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17345
HGNC: HGNC:7107
Homologene: 1814
Xdh
Name: xanthine dehydrogenase
Synonyms: Xox1, xanthine oxidase, Xor, Xox-1, XO
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22436
VEGA: 17
Homologene: 324
Wap
Name: whey acidic protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 22373
Homologene: 137242
Dnaja2
Name: DnaJ heat shock protein family (Hsp40) member A2
Synonyms: 2010206B19Rik, mDj3, HIRIP4, DNJ3, PRO3015, 1500017M13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 56445
Homologene: 21193
Txnl4b
Name: thioredoxin-like 4B
Synonyms: D530025J19Rik, Dim2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234723
Homologene: 9880
Nfs1
Name: nitrogen fixation gene 1 (S. cerevisiae)
Synonyms: m-Nfs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18041
Homologene: 5463
3110082I17Rik
Name: RIKEN cDNA 3110082I17 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 73212
Homologene: 49901
Prdm15
Name: PR domain containing 15
Synonyms: E130018M06Rik, Zfp298
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 114604
Homologene: 56941
Ccdc138
Name: coiled-coil domain containing 138
Synonyms: 6230424H07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 76138
VEGA: 10
Homologene: 44912
Dmxl2
Name: Dmx-like 2
Synonyms: E130119P06Rik, 6430411K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235380
HGNC: HGNC:2938
Homologene: 41022
Aprt
Name: adenine phosphoribosyl transferase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11821
HGNC: HGNC:626
Homologene: 413
Rala
Name: v-ral simian leukemia viral oncogene A (ras related)
Synonyms: 3010001O15Rik, Ral, Rasl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 56044
HGNC: HGNC:9839
Homologene: 3942
Mcm9
Name: minichromosome maintenance 9 homologous recombination repair factor
Synonyms: Mcmdc1, 9030408O17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71567
VEGA: 10
Homologene: 13546
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: P1-Loop, Dnahc8, Hst6.7b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Synrg
Name: synergin, gamma
Synonyms: Ap1gbp1, L71-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217030
HGNC: HGNC:557
Homologene: 105680
Cul4a
Name: cullin 4A
Synonyms: 2810470J21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 99375
HGNC: HGNC:2554
Homologene: 81724
Ppp1r12c
Name: protein phosphatase 1, regulatory subunit 12C
Synonyms: Mbs85, 2410197A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232807
Homologene: 75071
Plxna2
Name: plexin A2
Synonyms: PlexA2, Plxn2, OCT, 2810428A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18845
HGNC: HGNC:9100
Homologene: 56427
Myo15
Name: myosin XV
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17910
HGNC: HGNC:7594
Homologene: 56504
Scn1a
Name: sodium channel, voltage-gated, type I, alpha
Synonyms: Nav1.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20265
Homologene: 21375
Tns2
Name: tensin 2
Synonyms: nph, Tenc1, nep
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 209039
VEGA: 15
Homologene: 37077
Chsy3
Name: chondroitin sulfate synthase 3
Synonyms: 4833446K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 78923
VEGA: 18
Homologene: 28624
Txndc11
Name: thioredoxin domain containing 11
Synonyms: EF-hand binding protein 1, EFP1, 2810408E11Rik, Txdc11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 106200
Homologene: 9301
Magi2
Name: membrane associated guanylate kinase, WW and PDZ domain containing 2
Synonyms: Magi-2, S-SCAM, Acvrinp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 50791
Homologene: 8189
Stab2
Name: stabilin 2
Synonyms: FEEL-2, STAB-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 192188
Homologene: 23022
Tro
Name: trophinin
Synonyms: necdin and trophinin like, magphinin-beta 2, Maged3l, magphinin-alpha, magphinin-gamma, magphinin, trophinin-2, Tnn, Maged3, Trol
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 56191
Homologene: 75113
Nr1i3
Name: nuclear receptor subfamily 1, group I, member 3
Synonyms: mCAR, MB67, CAR1, ESTM32, CAR, Care2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12355
HGNC: HGNC:7969
Homologene: 3759
Carmil3
Name: capping protein regulator and myosin 1 linker 3
Synonyms: Lrrc16b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 268747
VEGA: 14
Homologene: 74564
Mtpap
Name: mitochondrial poly(A) polymerase
Synonyms: Papd1, Tent6, 0610027A18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 67440
VEGA: 18
Homologene: 10008
Auh
Name: AU RNA binding protein/enoyl-coenzyme A hydratase
Synonyms: W91705
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 11992
HGNC: HGNC:890
Homologene: 1284
Slc5a3
Name: solute carrier family 5 (inositol transporters), member 3
Synonyms: Smit1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 53881
Homologene: 31412
Rev3l
Name: REV3 like, DNA directed polymerase zeta catalytic subunit
Synonyms: Sez4, Rev
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 19714
HGNC: HGNC:9968
Homologene: 48147
Pde4dip
Name: phosphodiesterase 4D interacting protein (myomegalin)
Synonyms: D130016K21Rik, Usmg4, D3Bwg1078e, 9430063L05Rik, 4732458A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 83679
Homologene: 66961
Aoc1
Name: amine oxidase, copper-containing 1
Synonyms: Abp1, 1600012D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 76507
HGNC: HGNC:80
Homologene: 68159
Abcd4
Name: ATP-binding cassette, sub-family D (ALD), member 4
Synonyms: Pxmp1l, P69r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 19300
VEGA: 12
HGNC: HGNC:68
Homologene: 3703
Vmn1r63
Name: vomeronasal 1 receptor 63
Synonyms: V1R1, V1rd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 81017
Homologene: 41799
Dennd3
Name: DENN/MADD domain containing 3
Synonyms: E030003N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 105841
Homologene: 28254
Olfr951
Name: olfactory receptor 951
Synonyms: GA_x6K02T2PVTD-33090395-33091330, MOR171-33P, MOR171-49
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258046
VEGA: 9
Homologene: 71961
Vmn2r58
Name: vomeronasal 2, receptor 58
Synonyms: EG628422
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 628422
Sipa1l2
Name: signal-induced proliferation-associated 1 like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244668
Homologene: 18956
Fmo1
Name: flavin containing monooxygenase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14261
HGNC: HGNC:3769
Homologene: 55520
Ttbk2
Name: tau tubulin kinase 2
Synonyms: TTK, 2610507N02Rik, B930008N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 140810
Homologene: 62795
Tekt1
Name: tektin 1
Synonyms: MT14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 21689
Homologene: 7973
Ccdc112
Name: coiled-coil domain containing 112
Synonyms: 8430438M01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240261
VEGA: 18
Homologene: 17617
Gc
Name: vitamin D binding protein
Synonyms: DBP, vitamin D binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14473
HGNC: HGNC:4187
Homologene: 486
Bmp4
Name: bone morphogenetic protein 4
Synonyms: Bmp2b1, Bmp2b-1, Bmp2b, Bmp-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 12159
HGNC: HGNC:1071
Homologene: 7247
Gpt2
Name: glutamic pyruvate transaminase (alanine aminotransferase) 2
Synonyms: 4631422C05Rik, ALT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 108682
Homologene: 68832
Olfr61
Name: olfactory receptor 61
Synonyms: IH7, MOR253-1, GA_x6K02T2PBJ9-42783826-42784758
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18362
Homologene: 79374
Slc4a1ap
Name: solute carrier family 4 (anion exchanger), member 1, adaptor protein
Synonyms: kanadaptin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20534
Homologene: 7543
Reep1
Name: receptor accessory protein 1
Synonyms: D6Ertd253e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 52250
Homologene: 41504
D5Ertd577e
Name: DNA segment, Chr 5, ERATO Doi 577, expressed
Synonyms: E330023J07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 320549
Homologene: 133100
Nsa2
Name: NSA2 ribosome biogenesis homolog
Synonyms: Nsa2p, LNR42, Yr29, 5730427N09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 59050
VEGA: 13
Homologene: 5844
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 162,830,014 bp
  • A to G, chromosome 1 at 171,214,425 bp
  • A to G, chromosome 1 at 175,899,469 bp
  • A to G, chromosome 1 at 194,643,934 bp
  • A to T, chromosome 2 at 66,328,553 bp
  • T to A, chromosome 2 at 79,454,595 bp
  • A to T, chromosome 2 at 120,773,815 bp
  • A to G, chromosome 2 at 156,128,583 bp
  • A to G, chromosome 2 at 168,756,123 bp
  • G to A, chromosome 2 at 173,228,133 bp
  • G to T, chromosome 3 at 97,715,552 bp
  • C to T, chromosome 5 at 20,465,909 bp
  • T to A, chromosome 5 at 31,528,139 bp
  • A to T, chromosome 5 at 65,296,014 bp
  • T to C, chromosome 5 at 73,101,476 bp
  • A to C, chromosome 5 at 89,439,523 bp
  • T to A, chromosome 5 at 95,482,897 bp
  • G to T, chromosome 5 at 139,455,442 bp
  • T to C, chromosome 6 at 48,905,655 bp
  • T to A, chromosome 6 at 71,795,215 bp
  • T to G, chromosome 6 at 113,565,204 bp
  • G to A, chromosome 7 at 4,486,584 bp
  • T to A, chromosome 7 at 5,802,752 bp
  • C to T, chromosome 7 at 41,864,074 bp
  • A to T, chromosome 7 at 135,700,283 bp
  • G to A, chromosome 7 at 140,637,835 bp
  • T to C, chromosome 8 at 13,133,668 bp
  • G to T, chromosome 8 at 85,525,573 bp
  • C to T, chromosome 8 at 85,540,386 bp
  • C to T, chromosome 8 at 109,572,777 bp
  • T to C, chromosome 8 at 122,575,529 bp
  • C to T, chromosome 8 at 125,423,205 bp
  • C to A, chromosome 8 at 125,450,383 bp
  • T to C, chromosome 9 at 39,394,382 bp
  • T to C, chromosome 9 at 54,369,878 bp
  • T to A, chromosome 10 at 39,846,210 bp
  • A to G, chromosome 10 at 53,615,980 bp
  • T to C, chromosome 10 at 58,538,270 bp
  • T to A, chromosome 10 at 86,969,277 bp
  • G to A, chromosome 11 at 6,638,550 bp
  • A to T, chromosome 11 at 60,477,572 bp
  • A to G, chromosome 11 at 72,344,894 bp
  • T to C, chromosome 11 at 75,647,686 bp
  • T to C, chromosome 11 at 84,001,920 bp
  • C to A, chromosome 11 at 107,073,827 bp
  • A to G, chromosome 12 at 84,605,042 bp
  • G to T, chromosome 13 at 12,434,460 bp
  • T to A, chromosome 13 at 17,882,446 bp
  • C to A, chromosome 13 at 52,929,457 bp
  • T to C, chromosome 13 at 92,773,164 bp
  • G to T, chromosome 13 at 97,135,534 bp
  • C to T, chromosome 14 at 46,385,714 bp
  • T to C, chromosome 14 at 55,496,976 bp
  • T to C, chromosome 15 at 73,547,577 bp
  • T to C, chromosome 15 at 102,110,606 bp
  • T to C, chromosome 16 at 11,084,321 bp
  • A to G, chromosome 16 at 92,077,928 bp
  • G to T, chromosome 16 at 97,797,745 bp
  • A to G, chromosome 17 at 30,755,041 bp
  • C to T, chromosome 17 at 73,893,595 bp
  • T to C, chromosome 18 at 4,380,670 bp
  • C to T, chromosome 18 at 46,299,298 bp
  • G to A, chromosome 18 at 49,865,122 bp
  • T to C, chromosome 18 at 59,408,998 bp
  • G to A, chromosome X at 150,655,052 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3787 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040754-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.