Strain Name:
C57BL/6J-MtgxR3808Btlr/Mmmh
Stock Number:
040765-MU
Citation ID:
RRID:MMRRC_040765-MU
Other Names:
R3808 (G1), C57BL/6J-MtgxR3808Btlr
Major Collection:

Gene Information

Sbf2
Name: SET binding factor 2
Synonyms: SBF2, 4833411B01Rik, mMTMH1, B430219L04Rik, Mtmr13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 319934
HGNC: HGNC:2135
Homologene: 41810
Ppp4c
Name: protein phosphatase 4, catalytic subunit
Synonyms: PPX, 1110002D08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56420
HGNC: HGNC:9319
Homologene: 2038
Plin3
Name: perilipin 3
Synonyms: 1300012C15Rik, Tip47, M6prbp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 66905
VEGA: 17
Homologene: 4247
Lrp2
Name: low density lipoprotein receptor-related protein 2
Synonyms: Megalin, Gp330, D230004K18Rik, b2b1625.2Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14725
HGNC: HGNC:6694
Homologene: 20952
Rgs12
Name: regulator of G-protein signaling 12
Synonyms: 4632412M04Rik, 1200016K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71729
HGNC: HGNC:9994
Homologene: 2195
Nbea
Name: neurobeachin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 26422
HGNC: HGNC:7648
Homologene: 69190
Armc9
Name: armadillo repeat containing 9
Synonyms: 5730415N24Rik, 3830422A13Rik, 4831423D23Rik, 4930438O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 78795
Homologene: 11847
Lin9
Name: lin-9 homolog (C. elegans)
Synonyms: 2700022J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 72568
Homologene: 35252
Glod4
Name: glyoxalase domain containing 4
Synonyms: 1700082G03Rik, 2700085E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67201
Homologene: 9376
Sall1
Name: spalt like transcription factor 1
Synonyms: Msal-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 58198
Homologene: 2230
Med15
Name: mediator complex subunit 15
Synonyms: A230074L19Rik, Pcqap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 94112
VEGA: 16
Smchd1
Name: SMC hinge domain containing 1
Synonyms: 4931400A14Rik, MommeD1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 74355
Homologene: 23665
Dock4
Name: dedicator of cytokinesis 4
Synonyms: EST N28122, 6330411N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238130
VEGA: 12
Homologene: 56680
Eftud2
Name: elongation factor Tu GTP binding domain containing 2
Synonyms: U5-116kD, 116kDa, Snrp116
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20624
Homologene: 3133
Als2
Name: alsin Rho guanine nucleotide exchange factor
Synonyms: Als2cr6, 3222402C23Rik, 9430073A21Rik, Alsin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74018
HGNC: HGNC:443
Homologene: 23264
Tiam1
Name: T cell lymphoma invasion and metastasis 1
Synonyms: D16Ium10, D16Ium10e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 21844
Homologene: 2443
Clptm1l
Name: CLPTM1-like
Synonyms: C130052I12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218335
VEGA: 13
Homologene: 12767
Acaca
Name: acetyl-Coenzyme A carboxylase alpha
Synonyms: acetyl-CoA carboxylase, Acc1, LOC327983, Acac, A530025K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 107476
HGNC: HGNC:84
Homologene: 31015
Atp2b1
Name: ATPase, Ca++ transporting, plasma membrane 1
Synonyms: PMCA1, E130111D10Rik, 2810442I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67972
VEGA: 10
HGNC: HGNC:814
Homologene: 55597
Pfas
Name: phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)
Synonyms: 4432409B16Rik, Sofa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237823
HGNC: HGNC:8863
Homologene: 5970
Dtl
Name: denticleless E3 ubiquitin protein ligase
Synonyms: 5730564G15Rik, 2810047L02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 76843
Homologene: 32313
Stim1
Name: stromal interaction molecule 1
Synonyms: SIM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20866
Homologene: 20681
Paxip1
Name: PAX interacting (with transcription-activation domain) protein 1
Synonyms: PTIP, D5Ertd149e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 55982
HGNC: HGNC:8624
Carm1
Name: coactivator-associated arginine methyltransferase 1
Synonyms: Prmt4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 59035
Homologene: 10990
2700049A03Rik
Name: RIKEN cDNA 2700049A03 gene
Synonyms: talpid3, Ta3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 76967
Homologene: 8839
Sh2d3c
Name: SH2 domain containing 3C
Synonyms: Shep1, SH2-containing Eph receptor-binding protein 1, Cas/HEF1-associated signal transducer, Chat, Nsp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 27387
Homologene: 69145
Cd209b
Name: CD209b antigen
Synonyms: SIGNR1, mSIGNR1, 1810030I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 69165
HGNC: HGNC:1641
Homologene: 84858
Rdh9
Name: retinol dehydrogenase 9
Synonyms: Crad3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 103142
Homologene: 129514
Nr3c2
Name: nuclear receptor subfamily 3, group C, member 2
Synonyms: aldosterone receptor, Mlr, MR, mineralocorticoid receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 110784
HGNC: HGNC:7979
Homologene: 121495
F5
Name: coagulation factor V
Synonyms: Cf-5, Cf5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14067
HGNC: HGNC:3542
Homologene: 104
Rnf213
Name: ring finger protein 213
Synonyms: D11Ertd759e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 672511
Homologene: 45439
Svs1
Name: seminal vesicle secretory protein 1
Synonyms: SVS I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243377
Homologene: 18250
Unc80
Name: unc-80, NALCN activator
Synonyms: C230061B10Rik, C030018G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329178
Homologene: 122243
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 329628
Homologene: 14377
Prss43
Name: protease, serine 43
Synonyms: LOC272643, Tessp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 272643
Homologene: 138484
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20192
Homologene: 68151
Serpina3j
Name: serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3J
Synonyms: alpha-1 antiproteinase, Gm4931
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238395
HGNC: HGNC:16
Homologene: 120222
Lrp4
Name: low density lipoprotein receptor-related protein 4
Synonyms: 6430526J12Rik, Megf7, mdig
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228357
HGNC: HGNC:6696
Homologene: 17964
Arhgap5
Name: Rho GTPase activating protein 5
Synonyms: p190-B, p190B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 11855
VEGA: 12
HGNC: HGNC:675
Homologene: 907
Ros1
Name: Ros1 proto-oncogene
Synonyms: Ros-1, c-ros
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 19886
Homologene: 2207
Cdh17
Name: cadherin 17
Synonyms: HPT-1, BILL-cadherin, LI-cadherin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 12557
HGNC: HGNC:1756
Homologene: 56859
Grin2b
Name: glutamate receptor, ionotropic, NMDA2B (epsilon 2)
Synonyms: NMDAR2B, NR2B, Nmdar2b, GluRepsilon2, GluN2B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14812
HGNC: HGNC:4586
Homologene: 646
Aldh3a2
Name: aldehyde dehydrogenase family 3, subfamily A2
Synonyms: Ahd-3, Ahd-3r, Ahd3-r, Ahd3, Aldh4, Aldh4-r, FALDH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11671
HGNC: HGNC:403
Homologene: 55458
Atg2a
Name: autophagy related 2A
Synonyms: 1810013C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 329015
Homologene: 86985
Gm10033
Name: predicted gene 10033
Synonyms: E230024E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 378466
Vil1
Name: villin 1
Synonyms: Villin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22349
Homologene: 5169
Olfr1217
Name: olfactory receptor 1217
Synonyms: GA_x6K02T2Q125-50504545-50503631, MOR233-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258903
Homologene: 73985
Zfp267
Name: zinc finger protein 267
Synonyms: D3Ertd254e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 241944
Homologene: 117700
Olfr982
Name: olfactory receptor 982
Synonyms: GA_x6K02T2PVTD-33772307-33773260, MOR223-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258853
VEGA: 9
Homologene: 17415
Cntnap3
Name: contactin associated protein-like 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238680
VEGA: 13
Homologene: 129602
Eif2b4
Name: eukaryotic translation initiation factor 2B, subunit 4 delta
Synonyms: Eif2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13667
HGNC: HGNC:3260
Homologene: 5976
Kcnj12
Name: potassium inwardly-rectifying channel, subfamily J, member 12
Synonyms: Kir2.2, IRK2, MB-IRK2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16515
HGNC: HGNC:6258
Homologene: 7793
Slamf1
Name: signaling lymphocytic activation molecule family member 1
Synonyms: IPO-3, CD150, ESTM51, CDw150, Slam
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 27218
Homologene: 48162
Creb3l2
Name: cAMP responsive element binding protein 3-like 2
Synonyms: BBF2H7, C530025K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 208647
Homologene: 18690
Vmn1r202
Name: vomeronasal 1 receptor 202
Synonyms: V1ri7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 171258
Homologene: 110880
Klhdc3
Name: kelch domain containing 3
Synonyms: 1300011D16Rik, Peas
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 71765
VEGA: 17
Homologene: 14290
Rassf2
Name: Ras association (RalGDS/AF-6) domain family member 2
Synonyms: 3830431H01Rik, 9030412M04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 215653
HGNC: HGNC:9883
Homologene: 22840
Slc22a13
Name: solute carrier family 22 (organic cation transporter), member 13
Synonyms: ORCTL3, OCTL3, OCTL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 102570
VEGA: 9
HGNC: HGNC:8494
Homologene: 3140
Gdf1
Name: growth differentiation factor 1
Synonyms: Gdf-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14559
HGNC: HGNC:4214
Homologene: 105644
Olfr127
Name: olfactory receptor 127
Synonyms: MOR218-7, GA_x6K02T2PSCP-2354126-2355093
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258374
Homologene: 134080
Trim12a
Name: tripartite motif-containing 12A
Synonyms: 2310043C01Rik, Trim12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 76681
Pnck
Name: pregnancy upregulated non-ubiquitously expressed CaM kinase
Synonyms: Punc, Bstk3, Camk1b, CaMKIbeta2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 93843
Homologene: 128728
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 59,170,450 bp
  • T to C, chromosome 1 at 66,671,581 bp
  • T to C, chromosome 1 at 74,427,613 bp
  • C to A, chromosome 1 at 86,173,725 bp
  • A to T, chromosome 1 at 164,183,004 bp
  • A to G, chromosome 1 at 171,798,177 bp
  • A to G, chromosome 1 at 180,659,111 bp
  • A to C, chromosome 1 at 191,548,354 bp
  • T to C, chromosome 2 at 32,746,096 bp
  • T to C, chromosome 2 at 69,501,548 bp
  • G to T, chromosome 2 at 89,023,426 bp
  • T to A, chromosome 2 at 91,476,702 bp
  • C to T, chromosome 2 at 112,799,974 bp
  • T to C, chromosome 2 at 131,998,260 bp
  • T to G, chromosome 3 at 36,165,643 bp
  • T to G, chromosome 3 at 38,982,438 bp
  • T to C, chromosome 3 at 55,717,848 bp
  • A to T, chromosome 4 at 11,795,671 bp
  • A to G, chromosome 5 at 27,772,029 bp
  • A to G, chromosome 5 at 31,191,168 bp
  • A to G, chromosome 5 at 35,032,354 bp
  • A to G, chromosome 6 at 37,355,690 bp
  • C to T, chromosome 6 at 48,987,994 bp
  • A to G, chromosome 6 at 135,923,271 bp
  • T to A, chromosome 7 at 102,421,542 bp
  • G to A, chromosome 7 at 104,306,994 bp
  • C to A, chromosome 7 at 110,489,280 bp
  • C to T, chromosome 7 at 126,787,327 bp
  • T to C, chromosome 8 at 3,925,347 bp
  • A to T, chromosome 8 at 69,372,608 bp
  • A to G, chromosome 8 at 70,330,010 bp
  • G to A, chromosome 8 at 76,908,714 bp
  • G to A, chromosome 8 at 89,031,473 bp
  • T to C, chromosome 9 at 21,586,962 bp
  • A to T, chromosome 9 at 40,074,309 bp
  • A to T, chromosome 9 at 110,827,772 bp
  • T to C, chromosome 9 at 119,196,077 bp
  • T to G, chromosome 10 at 52,120,848 bp
  • A to G, chromosome 10 at 99,003,148 bp
  • T to A, chromosome 10 at 127,788,699 bp
  • G to A, chromosome 10 at 127,788,700 bp
  • A to G, chromosome 11 at 61,070,277 bp
  • G to T, chromosome 11 at 61,258,797 bp
  • T to C, chromosome 11 at 68,989,953 bp
  • A to G, chromosome 11 at 76,233,116 bp
  • A to T, chromosome 11 at 84,276,522 bp
  • A to T, chromosome 11 at 102,841,463 bp
  • A to G, chromosome 11 at 119,479,558 bp
  • T to G, chromosome 12 at 40,672,810 bp
  • A to G, chromosome 12 at 52,567,187 bp
  • G to T, chromosome 12 at 71,164,546 bp
  • A to T, chromosome 12 at 71,164,547 bp
  • A to T, chromosome 12 at 104,319,827 bp
  • T to C, chromosome 13 at 22,501,900 bp
  • A to G, chromosome 13 at 64,781,804 bp
  • A to C, chromosome 13 at 73,612,454 bp
  • C to T, chromosome 16 at 17,655,734 bp
  • A to T, chromosome 16 at 89,833,001 bp
  • T to C, chromosome 17 at 37,903,573 bp
  • T to A, chromosome 17 at 46,677,932 bp
  • C to A, chromosome 17 at 56,286,275 bp
  • A to T, chromosome 17 at 71,429,541 bp
  • A to G, chromosome 19 at 6,252,816 bp
  • T to A, chromosome X at 73,656,944 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3808 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040765-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.