Strain Name:
C57BL/6J-MtgxR3829Btlr/Mmmh
Stock Number:
040776-MU
Citation ID:
RRID:MMRRC_040776-MU
Other Names:
R3829 (G1), C57BL/6J-MtgxR3829Btlr
Major Collection:

Gene Information

Sufu
Name: SUFU negative regulator of hedgehog signaling
Synonyms: Su(Fu), 2810026F04Rik, b2b273Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 24069
Homologene: 9262
Orc1
Name: origin recognition complex, subunit 1
Synonyms: MmORC1, Orc1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18392
HGNC: HGNC:8487
Homologene: 31221
Tmem59l
Name: transmembrane protein 59-like
Synonyms: 5330410G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 67937
Homologene: 8104
Hap1
Name: huntingtin-associated protein 1
Synonyms: HAP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 15114
HGNC: HGNC:4812
Homologene: 2935
Rgs12
Name: regulator of G-protein signaling 12
Synonyms: 4632412M04Rik, 1200016K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71729
HGNC: HGNC:9994
Homologene: 2195
Mast4
Name: microtubule associated serine/threonine kinase family member 4
Synonyms: 4930420O11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 328329
Homologene: 42094
Cep104
Name: centrosomal protein 104
Synonyms: BC046331
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230967
Homologene: 44919
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: apollon, Bruce, A430032G04Rik, D630005A10Rik, A430040A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12211
Homologene: 7248
Etl4
Name: enhancer trap locus 4
Synonyms: Etl-4, E330027G05Rik, 6620402G01Rik, 9430077C05Rik, Skt, Sickle tail
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 208618
Homologene: 10477
Ncapg2
Name: non-SMC condensin II complex, subunit G2
Synonyms: Mtb, 5830426I05Rik, Luzp5, mCAP-G2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 76044
VEGA: 12
Homologene: 9820
Gpat4
Name: glycerol-3-phosphate acyltransferase 4
Synonyms: Agpat6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 102247
Homologene: 32425
Phip
Name: pleckstrin homology domain interacting protein
Synonyms: Wdr11, Ndrp, 2810004D21Rik, 4632404O06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 83946
Homologene: 41209
Cdc42bpg
Name: CDC42 binding protein kinase gamma (DMPK-like)
Synonyms: MRCKgamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 240505
Homologene: 28384
Lpcat1
Name: lysophosphatidylcholine acyltransferase 1
Synonyms: 2900035H07Rik, LPCAT, Aytl2, rd11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 210992
Homologene: 9871
Commd9
Name: COMM domain containing 9
Synonyms: 1810029F08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 76501
Homologene: 8584
Abcc5
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 5
Synonyms: Mrp5, Abcc5b, Abcc5a, 2900011L11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 27416
HGNC: HGNC:56
Homologene: 21164
Neo1
Name: neogenin
Synonyms: D930014N22Rik, 2610028H22Rik, Igdcc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 18007
VEGA: 9
HGNC: HGNC:7754
Homologene: 1870
Frem1
Name: Fras1 related extracellular matrix protein 1
Synonyms: eyem02Jus, heb, QBRICK, eyes2, crf11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329872
Homologene: 27049
Ube3b
Name: ubiquitin protein ligase E3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 117146
Homologene: 13775
Mcm9
Name: minichromosome maintenance 9 homologous recombination repair factor
Synonyms: 9030408O17Rik, Mcmdc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71567
VEGA: 10
Homologene: 13546
Bach2
Name: BTB and CNC homology, basic leucine zipper transcription factor 2
Synonyms: E030004N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 12014
Homologene: 7240
C1qtnf2
Name: C1q and tumor necrosis factor related protein 2
Synonyms: 1810033K05Rik, CTRP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69183
Homologene: 12899
Grpel1
Name: GrpE-like 1, mitochondrial
Synonyms: mt-GrpE#1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 17713
Homologene: 6992
Stk11
Name: serine/threonine kinase 11
Synonyms: Lkb1, Par-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 20869
Homologene: 393
Fbxw4
Name: F-box and WD-40 domain protein 4
Synonyms: dactylin, Fbw4, dactylyn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 30838
Homologene: 32197
Zfp445
Name: zinc finger protein 445
Synonyms: ZNF168
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235682
VEGA: 9
Homologene: 27832
Dhx37
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 37
Synonyms: LOC208144, LOC381671
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 208144
Homologene: 6641
Foxp2
Name: forkhead box P2
Synonyms: 2810043D05Rik, D0Kist7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 114142
Homologene: 134404
Srrm3
Name: serine/arginine repetitive matrix 3
Synonyms: 2900083I11Rik, SRm300-like, Srrm2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 58212
Homologene: 136723
Svep1
Name: sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
Synonyms: 4833413O10Rik, D430029O09Rik, 1110021D17Rik, Polydom
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 64817
Homologene: 23386
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, 2810003K23Rik, Dnahcl1, Dnahc17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: D11Ertd686e, Dnahc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Gm17521
Name: predicted gene, 17521
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Myh1
Name: myosin, heavy polypeptide 1, skeletal muscle, adult
Synonyms: MyHC-IId/x, Myhs-f2, Myhs-f, Myhsf2, A530084A17Rik, MYHC-IIX, myosin heavy chain 2X, IId, IId/x
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17879
HGNC: HGNC:7567
Homologene: 133718
Ppp2r1b
Name: protein phosphatase 2, regulatory subunit A, beta
Synonyms: 2410091N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 73699
HGNC: HGNC:9303
Homologene: 70244
Col4a1
Name: collagen, type IV, alpha 1
Synonyms: Col4a-1, Del(8)Bru44H, Del(8)44H, Bru, Svc, Raw, alpha1(IV) collagen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12826
HGNC: HGNC:2202
Homologene: 20437
Vmn2r91
Name: vomeronasal 2, receptor 91
Synonyms: EG665210
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 665210
Homologene: 115024
A330008L17Rik
Name: RIKEN cDNA A330008L17 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234624
Cbr2
Name: carbonyl reductase 2
Synonyms: MLCR, lung carbonyl reductase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12409
Homologene: 104184
Tiam2
Name: T cell lymphoma invasion and metastasis 2
Synonyms: STEF, 3000002F19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 24001
VEGA: 17
Homologene: 40796
Fam234a
Name: family with sequence similarity 234, member A
Synonyms: Itfg3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 106581
Homologene: 12932
Veph1
Name: ventricular zone expressed PH domain-containing 1
Synonyms: Veph, 2810471M23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 72789
Homologene: 11624
Cbs
Name: cystathionine beta-synthase
Synonyms: HIP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12411
Homologene: 37258
Mrpl50
Name: mitochondrial ribosomal protein L50
Synonyms: D4Wsu125e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 28028
Homologene: 32436
Tmprss11b
Name: transmembrane protease, serine 11B
Synonyms: 9930019B18Rik, Tmprss11bnl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 319875
Homologene: 64599
Ralb
Name: v-ral simian leukemia viral oncogene B
Synonyms: 5730472O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 64143
HGNC: HGNC:9840
Homologene: 20632
Chil6
Name: chitinase-like 6
Synonyms: BYm, BC051070
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229688
Homologene: 77638
Cplane2
Name: ciliogenesis and planar polarity effector 2
Synonyms: LOC279260, 6330545A04Rik, b2b2827Clo, b2b2804Clo, Rsg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 76166
Homologene: 12793
Yrdc
Name: yrdC domain containing (E.coli)
Synonyms: IRIP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230734
Homologene: 11635
Olfr99
Name: olfactory receptor 99
Synonyms: MOR156-1, GA_x6K02T2PSCP-1720261-1719344
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258508
Homologene: 74030
4931414P19Rik
Name: RIKEN cDNA 4931414P19 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 74359
VEGA: 14
Homologene: 11078
Myg1
Name: melanocyte proliferating gene 1
Synonyms: Gamm1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 60315
Homologene: 5853
4933411K16Rik
Name: RIKEN cDNA 4933411K16 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66765
Homologene: 83936
Cln5
Name: ceroid-lipofuscinosis, neuronal 5
Synonyms: A730075N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 211286
VEGA: 14
HGNC: HGNC:2076
Homologene: 4738
Rtkn2
Name: rhotekin 2
Synonyms: B130039D23Rik, RTKN2, Mbf, Plekhk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 170799
Homologene: 17065
Cx3cl1
Name: chemokine (C-X3-C motif) ligand 1
Synonyms: fractalkine, CX3C, neurotactin, D8Bwg0439e, Scyd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 20312
Homologene: 2251
Fam199x
Name: family with sequence similarity 199, X-linked
Synonyms: BC031748
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 245622
Homologene: 17156
Cyct
Name: cytochrome c, testis
Synonyms: T-Cc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 13067
Homologene: 129551
Gm10259
Name: predicted pseudogene 10259
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 100039592
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 119,471,717 bp
  • T to C, chromosome 2 at 20,785,421 bp
  • T to C, chromosome 2 at 76,354,168 bp
  • C to A, chromosome 2 at 101,897,141 bp
  • T to G, chromosome 3 at 25,212,529 bp
  • T to A, chromosome 3 at 66,159,327 bp
  • A to T, chromosome 3 at 106,405,958 bp
  • T to A, chromosome 4 at 32,563,150 bp
  • T to C, chromosome 4 at 49,514,539 bp
  • A to G, chromosome 4 at 58,096,177 bp
  • A to T, chromosome 4 at 82,998,930 bp
  • T to A, chromosome 4 at 108,605,631 bp
  • T to A, chromosome 4 at 124,851,761 bp
  • C to T, chromosome 4 at 141,218,589 bp
  • T to G, chromosome 4 at 153,984,943 bp
  • G to A, chromosome 5 at 34,966,015 bp
  • T to A, chromosome 5 at 36,469,483 bp
  • T to C, chromosome 5 at 86,661,590 bp
  • C to A, chromosome 5 at 114,399,951 bp
  • T to C, chromosome 5 at 125,431,613 bp
  • A to G, chromosome 5 at 135,857,214 bp
  • C to T, chromosome 6 at 15,379,831 bp
  • C to A, chromosome 8 at 11,209,650 bp
  • G to A, chromosome 8 at 23,180,155 bp
  • A to G, chromosome 8 at 70,487,301 bp
  • A to T, chromosome 8 at 94,777,306 bp
  • A to G, chromosome 8 at 99,421,757 bp
  • A to G, chromosome 9 at 50,862,494 bp
  • A to G, chromosome 9 at 58,913,169 bp
  • A to G, chromosome 9 at 82,871,645 bp
  • T to C, chromosome 9 at 122,853,077 bp
  • C to A, chromosome 10 at 53,630,141 bp
  • A to T, chromosome 10 at 67,997,626 bp
  • T to C, chromosome 10 at 80,127,948 bp
  • A to G, chromosome 11 at 43,491,321 bp
  • A to G, chromosome 11 at 65,970,141 bp
  • A to G, chromosome 11 at 67,205,597 bp
  • G to T, chromosome 11 at 100,356,021 bp
  • G to A, chromosome 11 at 118,041,158 bp
  • A to T, chromosome 11 at 120,730,452 bp
  • A to T, chromosome 12 at 116,407,318 bp
  • T to C, chromosome 13 at 73,489,093 bp
  • G to T, chromosome 13 at 102,738,811 bp
  • G to T, chromosome 14 at 54,584,509 bp
  • A to G, chromosome 14 at 103,073,359 bp
  • G to C, chromosome 15 at 102,337,736 bp
  • C to A, chromosome 16 at 20,365,865 bp
  • C to G, chromosome 17 at 3,507,701 bp
  • T to G, chromosome 17 at 18,105,497 bp
  • T to C, chromosome 17 at 26,218,189 bp
  • T to C, chromosome 17 at 31,617,381 bp
  • T to A, chromosome 17 at 37,280,249 bp
  • A to G, chromosome 17 at 74,655,178 bp
  • T to C, chromosome 19 at 6,317,645 bp
  • A to T, chromosome 19 at 42,052,883 bp
  • A to G, chromosome 19 at 45,579,804 bp
  • C to T, chromosome 19 at 46,483,591 bp
  • C to A, chromosome X at 123,029,225 bp
  • T to C, chromosome X at 137,072,186 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3829 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040776-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.