Strain Name:
C57BL/6J-MtgxR3840Btlr/Mmmh
Stock Number:
040780-MU
Citation ID:
RRID:MMRRC_040780-MU
Other Names:
R3840 (G1), C57BL/6J-MtgxR3840Btlr
Major Collection:

Gene Information

Osbpl1a
Name: oxysterol binding protein-like 1A
Synonyms: G430090F17Rik, LOC328902
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 64291
Homologene: 84746
Abcc8
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 8
Synonyms: SUR1, Sur, D930031B21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 20927
HGNC: HGNC:59
Homologene: 68048
Tmem87b
Name: transmembrane protein 87B
Synonyms: 2610301K12Rik, 2810431I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 72477
Homologene: 69513
Cdca2
Name: cell division cycle associated 2
Synonyms: 2610311M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 108912
Homologene: 18444
Fmn2
Name: formin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 54418
Homologene: 137334
Wac
Name: WW domain containing adaptor with coiled-coil
Synonyms: 1110067P07Rik, Wwp4, A230035H12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225131
Homologene: 41148
Psmd12
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
Synonyms: P55, 1500002F15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 66997
HGNC: HGNC:9557
Homologene: 2109
Epc2
Name: enhancer of polycomb homolog 2
Synonyms: D2Ertd694e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227867
Homologene: 32274
Nr2c2
Name: nuclear receptor subfamily 2, group C, member 2
Synonyms: TAK1, Tr4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 22026
HGNC: HGNC:7972
Homologene: 2475
Dtna
Name: dystrobrevin alpha
Synonyms: a-DB-1, 87K protein, 2210407P21Rik, alpha-dystrobrevin, A0, adbn, Dtn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 13527
VEGA: 18
HGNC: HGNC:3057
Homologene: 20362
Ate1
Name: arginyltransferase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11907
HGNC: HGNC:782
Homologene: 31420
Zfp617
Name: zinc finger protein 617
Synonyms: Zfps11-6, Zinc finger protein s11-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 170938
Homologene: 135689
Hsph1
Name: heat shock 105kDa/110kDa protein 1
Synonyms: Hsp105, HSP110, hsp110/105, hsp-E7I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 15505
Homologene: 21322
Snap91
Name: synaptosomal-associated protein 91
Synonyms: 91kDa, F1-20, AP180
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 20616
Homologene: 8429
Mastl
Name: microtubule associated serine/threonine kinase-like
Synonyms: 2700091H24Rik, THC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 67121
Homologene: 12086
Fam171b
Name: family with sequence similarity 171, member B
Synonyms: D430039N05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241520
Homologene: 18462
Zap70
Name: zeta-chain (TCR) associated protein kinase
Synonyms: ZAP-70, TZK, Srk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 22637
Homologene: 839
Erbb3
Name: erb-b2 receptor tyrosine kinase 3
Synonyms: HER3, Erbb3r, Erbb-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 13867
HGNC: HGNC:3431
Homologene: 20457
Gask1b
Name: golgi associated kinase 1B
Synonyms: 1110032E23Rik, 2210419I08Rik, Fam198b, Ened
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 68659
Homologene: 9590
F11r
Name: F11 receptor
Synonyms: Jcam1, BV11 antigen, ESTM33, JAM-1, JAM-A, Ly106
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 16456
Homologene: 14255
Dennd6a
Name: DENN/MADD domain containing 6A
Synonyms: A630054L15Rik, Fam116a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 211922
Homologene: 13503
Elmsan1
Name: ELM2 and Myb/SANT-like domain containing 1
Synonyms: C130039O16Rik, 9430029N19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 238317
Homologene: 19330
Pkd1l1
Name: polycystic kidney disease 1 like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 171395
Homologene: 51376
Lrrc4c
Name: leucine rich repeat containing 4C
Synonyms: netrin g1 ligand, 6430556C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241568
Homologene: 18696
Mocos
Name: molybdenum cofactor sulfurase
Synonyms: 1110018O12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 68591
VEGA: 18
Homologene: 9931
Tnfrsf11b
Name: tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
Synonyms: OPG, Opg, osteoclastogenesis inhibitory factor, TR1, OCIF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 18383
VEGA: 15
Homologene: 1912
Tmprss7
Name: transmembrane serine protease 7
Synonyms: LOC385645, matriptase-3, B230219I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 208171
Homologene: 18178
Cmya5
Name: cardiomyopathy associated 5
Synonyms: 2310076E16Rik, Myospryn, 2310076E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 76469
VEGA: 13
Homologene: 137367
Kcnu1
Name: potassium channel, subfamily U, member 1
Synonyms: Slo3, Kcnma3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 16532
Homologene: 7392
Myef2
Name: myelin basic protein expression factor 2, repressor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17876
Homologene: 69079
Neb
Name: nebulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Tro
Name: trophinin
Synonyms: Tnn, magphinin-gamma, magphinin-alpha, magphinin-beta 2, magphinin, Trol, Maged3l, necdin and trophinin like, trophinin-2, Maged3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 56191
Homologene: 75113
Slc4a11
Name: solute carrier family 4, sodium bicarbonate transporter-like, member 11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 269356
Homologene: 12931
Col6a5
Name: collagen, type VI, alpha 5
Synonyms: Gm7455, Col6a5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 665033
Homologene: 122792
Heg1
Name: heart development protein with EGF-like domains 1
Synonyms: 9530025L16Rik, 5530401I02Rik, 4632417D23Rik, LOC268884
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 77446
Homologene: 35276
Rap1gap
Name: Rap1 GTPase-activating protein
Synonyms: 1300019I11Rik, Rap1ga1, Gap, 2310004O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 110351
HGNC: HGNC:9858
Homologene: 2163
Olfr593
Name: olfactory receptor 593
Synonyms: GA_x6K02T2PBJ9-5927412-5928362, MOR24-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258378
Homologene: 27147
Cntnap5b
Name: contactin associated protein-like 5B
Synonyms: Caspr5-2, C230078M14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241175
Homologene: 104295
Tbpl1
Name: TATA box binding protein-like 1
Synonyms: TRF2, TRP, Tlp, TLF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 237336
Homologene: 3577
Fam83c
Name: family with sequence similarity 83, member C
Synonyms: 5530400B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 71405
Homologene: 18669
Ggt1
Name: gamma-glutamyltransferase 1
Synonyms: dwg, CD224, Ggtp, GGT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 14598
HGNC: HGNC:4250
Homologene: 68450
4921524L21Rik
Name: RIKEN cDNA 4921524L21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 70901
VEGA: 18
Homologene: 78009
Btnl7-ps
Name: butyrophilin-like 7, pseudogene
Synonyms: Btnl7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 195349
Slc22a13
Name: solute carrier family 22 (organic cation transporter), member 13
Synonyms: OCTL3, ORCTL3, OCTL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 102570
VEGA: 9
HGNC: HGNC:8494
Homologene: 3140
Olfr129
Name: olfactory receptor 129
Synonyms: GA_x6K02T2PSCP-2503741-2502776, MOR263-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 258324
Homologene: 133641
C530008M17Rik
Name: RIKEN cDNA C530008M17 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 320827
Homologene: 136278
Jhy
Name: junctional cadherin complex regulator
Synonyms: 4931429I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 70989
Homologene: 11726
Tulp1
Name: tubby like protein 1
Synonyms: Tulp1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 22157
Homologene: 2491
Medag
Name: mesenteric estrogen dependent adipogenesis
Synonyms: MEDA-4, 6330406I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 70717
Homologene: 12364
Tnfrsf23
Name: tumor necrosis factor receptor superfamily, member 23
Synonyms: Tnfrh1, mDcTrailr1, mSOB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 79201
Homologene: 84848
BC035947
Name: cDNA sequence BC035947
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
Podxl
Name: podocalyxin-like
Synonyms: podocalyxin, Podxl1, Pclp1, PC, Ly102
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 27205
HGNC: HGNC:9171
Homologene: 137260
Otud1
Name: OTU domain containing 1
Synonyms: 4933428L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 71198
Homologene: 45953
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 36,778,417 bp
  • G to T, chromosome 1 at 78,497,845 bp
  • C to T, chromosome 1 at 100,383,477 bp
  • G to T, chromosome 1 at 171,460,889 bp
  • GAAGA to GAAGAAAGA, chromosome 1 at 174,582,033 bp
  • G to T, chromosome 2 at 19,658,743 bp
  • T to C, chromosome 2 at 23,140,551 bp
  • A to G, chromosome 2 at 49,488,738 bp
  • C to A, chromosome 2 at 52,207,660 bp
  • C to A, chromosome 2 at 83,880,062 bp
  • A to G, chromosome 2 at 97,630,192 bp
  • A to T, chromosome 2 at 125,095,762 bp
  • T to A, chromosome 2 at 128,826,384 bp
  • A to G, chromosome 2 at 130,688,054 bp
  • C to T, chromosome 2 at 155,834,748 bp
  • T to A, chromosome 3 at 79,908,590 bp
  • T to C, chromosome 4 at 137,717,447 bp
  • A to T, chromosome 5 at 76,859,011 bp
  • T to A, chromosome 5 at 149,427,423 bp
  • T to A, chromosome 5 at 149,620,715 bp
  • C to T, chromosome 6 at 31,523,081 bp
  • C to T, chromosome 6 at 92,163,138 bp
  • A to G, chromosome 7 at 46,108,100 bp
  • G to A, chromosome 7 at 103,212,693 bp
  • A to T, chromosome 7 at 130,516,137 bp
  • A to G, chromosome 7 at 143,681,529 bp
  • G to T, chromosome 8 at 25,885,352 bp
  • G to A, chromosome 8 at 71,932,117 bp
  • T to A, chromosome 9 at 40,944,846 bp
  • C to T, chromosome 9 at 86,839,565 bp
  • T to C, chromosome 9 at 105,928,611 bp
  • T to C, chromosome 9 at 119,208,789 bp
  • A to G, chromosome 10 at 22,711,908 bp
  • T to A, chromosome 10 at 75,581,385 bp
  • A to T, chromosome 10 at 128,570,324 bp
  • T to C, chromosome 11 at 8,889,050 bp
  • T to C, chromosome 11 at 107,485,572 bp
  • T to C, chromosome 12 at 84,171,609 bp
  • A to G, chromosome 13 at 93,094,632 bp
  • T to C, chromosome 14 at 26,626,768 bp
  • A to T, chromosome 14 at 67,680,271 bp
  • T to A, chromosome 15 at 54,252,082 bp
  • T to A, chromosome 16 at 33,719,856 bp
  • T to A, chromosome 16 at 45,660,832 bp
  • A to G, chromosome 17 at 28,353,715 bp
  • A to G, chromosome 17 at 34,542,576 bp
  • A to G, chromosome 17 at 38,055,348 bp
  • A to T, chromosome 18 at 6,620,104 bp
  • C to A, chromosome 18 at 7,918,535 bp
  • A to G, chromosome 18 at 12,756,319 bp
  • A to G, chromosome 18 at 23,595,628 bp
  • C to T, chromosome 18 at 24,676,624 bp
  • A to G, chromosome X at 150,646,202 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3840 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040780-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.