Strain Name:
C57BL/6J-MtgxR3883Btlr/Mmmh
Stock Number:
040796-MU
Citation ID:
RRID:MMRRC_040796-MU
Other Names:
R3883 (G1), C57BL/6J-MtgxR3883Btlr
Major Collection:

Gene Information

Cdk17
Name: cyclin-dependent kinase 17
Synonyms: 6430598J10Rik, Pctk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237459
VEGA: 10
HGNC: HGNC:8750
Homologene: 55666
Mrtfb
Name: myocardin related transcription factor B
Synonyms: MRTF-B, Gt4-1, Mrtfb, Mkl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 239719
Homologene: 40917
Kat2b
Name: K(lysine) acetyltransferase 2B
Synonyms: A930006P13Rik, Pcaf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 18519
HGNC: HGNC:8638
Homologene: 20834
Fbxo22
Name: F-box protein 22
Synonyms: 1600016C16Rik, 0610033L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71999
Homologene: 12433
Rabggtb
Name: Rab geranylgeranyl transferase, b subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 19352
HGNC: HGNC:9796
Homologene: 3371
Zbtb32
Name: zinc finger and BTB domain containing 32
Synonyms: Tzfp, 4930524C15Rik, PLZP, Rog
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 58206
Homologene: 8661
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Pam, C130061D10Rik, Phr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105689
Homologene: 9005
Epc1
Name: enhancer of polycomb homolog 1
Synonyms: A930032N02Rik, 5730566F07Rik, 2400007E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 13831
Homologene: 32627
Ddx42
Name: DEAD box helicase 42
Synonyms: B430002H05Rik, 1810047H21Rik, SF3b125, DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 72047
Homologene: 49137
Epb41l3
Name: erythrocyte membrane protein band 4.1 like 3
Synonyms: NBL3, 4.1B, DAL1P, Epb4.1l3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13823
HGNC: HGNC:3380
Homologene: 49308
Cntn2
Name: contactin 2
Synonyms: Tax, TAG-1, axonin, D130012K04Rik, TAG1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 21367
HGNC: HGNC:2172
Homologene: 3720
Hipk2
Name: homeodomain interacting protein kinase 2
Synonyms: Stank, 1110014O20Rik, B230339E18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 15258
Homologene: 68766
Trpm4
Name: transient receptor potential cation channel, subfamily M, member 4
Synonyms: TRPM4B, 1110030C19Rik, LTRPC4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 68667
Homologene: 23033
Tap1
Name: transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
Synonyms: RING4, PSF-1, MTP1, Tap-1, Ham-1, Ham1, Abcb2, TAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 21354
HGNC: HGNC:43
Homologene: 495
C3
Name: complement component 3
Synonyms: complement factor 3, acylation stimulating protein, Plp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12266
HGNC: HGNC:1318
Homologene: 68031
Neto2
Name: neuropilin (NRP) and tolloid (TLL)-like 2
Synonyms: 5530601C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 74513
Homologene: 32387
Pigk
Name: phosphatidylinositol glycan anchor biosynthesis, class K
Synonyms: 3000001O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 329777
HGNC: HGNC:8965
Homologene: 4002
Peak1
Name: pseudopodium-enriched atypical kinase 1
Synonyms: 1110049L02Rik, NKF3 kinase family member, C230081A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244895
Homologene: 18259
Mavs
Name: mitochondrial antiviral signaling protein
Synonyms: IPS-1, D430028G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228607
Homologene: 17004
F2
Name: coagulation factor II
Synonyms: prothrombin, Cf-2, Cf2, FII, thrombin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14061
HGNC: HGNC:3535
Homologene: 426
Dchs1
Name: dachsous cadherin related 1
Synonyms: C130033F22Rik, 3110041P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233651
Homologene: 2771
Dnah11
Name: dynein, axonemal, heavy chain 11
Synonyms: lrd, b2b1203Clo, b2b1279Clo, b2b598Clo, b2b1289Clo, b2b1727Clo, Dnahc11, avc4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 13411
HGNC: HGNC:2942
Homologene: 2801
Ush2a
Name: usherin
Synonyms: MUSH2A, A930011D15Rik, LOC381317, LOC269160, A930037M10Rik, Ushrn, Ush2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22283
Homologene: 66151
Arsi
Name: arylsulfatase i
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 545260
Homologene: 44428
Slc5a8
Name: solute carrier family 5 (iodide transporter), member 8
Synonyms: SMCT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216225
VEGA: 10
Homologene: 64832
Gls2
Name: glutaminase 2 (liver, mitochondrial)
Synonyms: Lga, A330074B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216456
Homologene: 40861
Acsl1
Name: acyl-CoA synthetase long-chain family member 1
Synonyms: Acas1, Facl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14081
HGNC: HGNC:3569
Homologene: 37561
Lgsn
Name: lengsin, lens protein with glutamine synthetase domain
Synonyms: Lgs, lengsin, Gluld1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 266744
Homologene: 9569
Pde4dip
Name: phosphodiesterase 4D interacting protein (myomegalin)
Synonyms: D3Bwg1078e, 4732458A06Rik, D130016K21Rik, 9430063L05Rik, Usmg4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 83679
Homologene: 66961
Fmnl1
Name: formin-like 1
Synonyms: 8030453N10Rik, formin-related gene in leukocytes
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 57778
HGNC: HGNC:1212
Homologene: 135620
Folh1
Name: folate hydrolase 1
Synonyms: mopsm, prostate-specific membrane antigen, glutamate carboxypeptidase II, GCP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 53320
HGNC: HGNC:3788
Homologene: 55826
Edn1
Name: endothelin 1
Synonyms: ET-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 13614
VEGA: 13
HGNC: HGNC:3176
Homologene: 1476
Vmn2r58
Name: vomeronasal 2, receptor 58
Synonyms: EG628422
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 628422
Enthd1
Name: ENTH domain containing 1
Synonyms: LOC383075
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 383075
VEGA: 15
Homologene: 45131
Mtrf1
Name: mitochondrial translational release factor 1
Synonyms: A830062K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 211253
VEGA: 14
HGNC: HGNC:7469
Homologene: 20903
Ano5
Name: anoctamin 5
Synonyms: Gdd1, Tmem16e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233246
Homologene: 100071
Gm15446
Name: predicted gene 15446
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100642166
Ankmy1
Name: ankyrin repeat and MYND domain containing 1
Synonyms: 4930483I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241158
Homologene: 9561
Sprr1a
Name: small proline-rich protein 1A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20753
Homologene: 105698
Kif4-ps
Name: kinesin family member 4, pseudogene
Synonyms: Kif4b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 74947
Olfr961
Name: olfactory receptor 961
Synonyms: GA_x6K02T2PVTD-33343617-33344561, MOR224-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258497
VEGA: 9
Homologene: 74020
Ngly1
Name: N-glycanase 1
Synonyms: 1110002C09Rik, Png1, PNGase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 59007
Homologene: 10117
Olfr1339
Name: olfactory receptor 1339
Synonyms: GA_x6K02T2QD9B-18815145-18814198, MOR258-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 258851
Homologene: 27280
Zbtb7a
Name: zinc finger and BTB domain containing 7a
Synonyms: 9030619K07Rik, 9130006G12Rik, Lrf, FBI-1, Zbtb7, Pokemon, Leukemia/lymphoma Related Factor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16969
Homologene: 7820
Serpinb13
Name: serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 13
Synonyms: headpin, PI13, HURPIN, HUR7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241196
HGNC: HGNC:8944
Homologene: 22718
Cracd
Name: capping protein inhibiting regulator of actin
Synonyms: C530008M17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 320827
Homologene: 136278
Reep6
Name: receptor accessory protein 6
Synonyms: Dp1l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70335
Homologene: 133833
Klk1b16
Name: kallikrein 1-related peptidase b16
Synonyms: mGk-16, Klk16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16615
HGNC: HGNC:6364
Homologene: 68141
Bhlhe41
Name: basic helix-loop-helix family, member e41
Synonyms: DEC2, Sharp1, Bhlhb3, 6430520M22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 79362
Homologene: 137371
CAAA01083517.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Batf2
Name: basic leucine zipper transcription factor, ATF-like 2
Synonyms: 4933430F08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 74481
Homologene: 12569
Gm10220
Name: predicted gene 10220
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 434689
Homologene: 69402
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 31,176,459 bp
  • T to G, chromosome 1 at 92,886,152 bp
  • T to C, chromosome 1 at 106,998,572 bp
  • A to G, chromosome 1 at 132,528,939 bp
  • A to T, chromosome 1 at 183,390,948 bp
  • T to C, chromosome 1 at 188,263,382 bp
  • A to T, chromosome 2 at 91,630,138 bp
  • T to C, chromosome 2 at 131,245,298 bp
  • G to A, chromosome 3 at 92,484,520 bp
  • T to C, chromosome 3 at 97,713,188 bp
  • T to C, chromosome 3 at 152,714,195 bp
  • A to G, chromosome 3 at 153,910,780 bp
  • T to C, chromosome 4 at 118,734,685 bp
  • A to C, chromosome 5 at 26,116,910 bp
  • T to A, chromosome 5 at 76,856,574 bp
  • G to T, chromosome 5 at 109,940,447 bp
  • A to G, chromosome 6 at 38,699,265 bp
  • A to G, chromosome 6 at 145,864,563 bp
  • A to G, chromosome 7 at 30,591,144 bp
  • A to T, chromosome 7 at 41,864,490 bp
  • T to C, chromosome 7 at 44,139,463 bp
  • C to T, chromosome 7 at 45,321,998 bp
  • T to A, chromosome 7 at 51,566,304 bp
  • A to G, chromosome 7 at 86,775,656 bp
  • A to G, chromosome 7 at 105,762,563 bp
  • C to T, chromosome 8 at 46,527,191 bp
  • A to G, chromosome 8 at 85,663,265 bp
  • A to G, chromosome 9 at 39,647,124 bp
  • A to T, chromosome 9 at 55,223,262 bp
  • A to T, chromosome 9 at 56,241,354 bp
  • G to A, chromosome 10 at 80,335,535 bp
  • T to C, chromosome 10 at 81,148,025 bp
  • T to A, chromosome 10 at 88,902,463 bp
  • T to C, chromosome 10 at 93,212,077 bp
  • C to T, chromosome 10 at 128,207,017 bp
  • A to G, chromosome 11 at 103,182,114 bp
  • T to A, chromosome 11 at 106,247,692 bp
  • G to T, chromosome 12 at 101,146,214 bp
  • T to C, chromosome 12 at 117,978,453 bp
  • T to A, chromosome 13 at 42,301,906 bp
  • A to G, chromosome 14 at 16,270,574 bp
  • A to G, chromosome 14 at 79,419,267 bp
  • A to C, chromosome 14 at 103,295,250 bp
  • T to C, chromosome 15 at 80,509,170 bp
  • T to A, chromosome 16 at 13,401,458 bp
  • T to A, chromosome 17 at 34,193,258 bp
  • T to A, chromosome 17 at 53,654,428 bp
  • T to C, chromosome 17 at 57,217,173 bp
  • C to T, chromosome 17 at 69,274,116 bp
  • T to C, chromosome 18 at 6,452,258 bp
  • G to A, chromosome 18 at 60,916,651 bp
  • T to C, chromosome 19 at 6,171,295 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3883 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040796-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.