Strain Name:
C57BL/6J-MtgxR3928Btlr/Mmmh
Stock Number:
040823-MU
Citation ID:
RRID:MMRRC_040823-MU
Other Names:
R3928 (G1), C57BL/6J-MtgxR3928Btlr
Major Collection:

Gene Information

Kif3a
Name: kinesin family member 3A
Synonyms: Kns3, kinesin-II subunit, Kif3, N-4 kinesin, Kifl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16568
HGNC: HGNC:6319
Homologene: 38266
Inpp5d
Name: inositol polyphosphate-5-phosphatase D
Synonyms: SHIP-1, SHIP1, Src homology 2 domain-containing inositol-5-phosphatase, s-SHIP, SHIP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 16331
HGNC: HGNC:6079
Homologene: 4046
Zfp710
Name: zinc finger protein 710
Synonyms: 5430400N05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 209225
Homologene: 19625
Trmo
Name: tRNA methyltransferase O
Synonyms: 5830415F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 74753
Homologene: 32316
Top1
Name: topoisomerase (DNA) I
Synonyms: D130064I21Rik, Top-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 21969
Homologene: 2467
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: A430032G04Rik, apollon, D630005A10Rik, A430040A19Rik, Bruce
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 12211
Homologene: 7248
Clasp2
Name: CLIP associating protein 2
Synonyms: 8030404L10Rik, 1500004F14Rik, CLASP2gamma, CLASP2beta, CLASP2, CLASP2alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 76499
VEGA: 9
Homologene: 24944
Atrx
Name: ATRX, chromatin remodeler
Synonyms: Hp1bp2, HP1-BP38, alpha thalassemia/mental retardation syndrome X-linked, XH2, 4833408C14Rik, Xnp, Rad54, DXHXS6677E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 22589
HGNC: HGNC:886
Homologene: 416
Tfcp2l1
Name: transcription factor CP2-like 1
Synonyms: Tcfcp2l1, LBP-9, Crtr-1, D930018N21Rik, 4932442M07Rik, Cp2l1, 1810030F05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 81879
Homologene: 8730
Myo9a
Name: myosin IXa
Synonyms: 4732465J09Rik, C130068I12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 270163
HGNC: HGNC:7608
Homologene: 21371
Abr
Name: active BCR-related gene
Synonyms: 6330400K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 109934
HGNC: HGNC:81
Homologene: 11081
Myo1d
Name: myosin ID
Synonyms: 9930104H07Rik, D11Ertd9e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 338367
HGNC: HGNC:7598
Homologene: 45576
Pirb
Name: paired Ig-like receptor B
Synonyms: Lilrb3, Gp91
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18733
HGNC: HGNC:6607
Homologene: 134028
Ctps
Name: cytidine 5'-triphosphate synthase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 51797
HGNC: HGNC:2519
Homologene: 20446
Pgp
Name: phosphoglycolate phosphatase
Synonyms: 1700012G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 67078
VEGA: 17
HGNC: HGNC:8909
Homologene: 5513
Tnrc6c
Name: trinucleotide repeat containing 6C
Synonyms: 9930033H14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217351
Homologene: 23137
Nphp3
Name: nephronophthisis 3 (adolescent)
Synonyms: pcy, nephrocystin 3, 3632410F03Rik, D330020E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 74025
HGNC: HGNC:7907
Homologene: 32697
Col13a1
Name: collagen, type XIII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 12817
HGNC: HGNC:2190
Homologene: 22421
Pkhd1
Name: polycystic kidney and hepatic disease 1
Synonyms: FPC, tigmin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241035
HGNC: HGNC:9016
Homologene: 16336
Xirp2
Name: xin actin-binding repeat containing 2
Synonyms: 2310008C07Rik, myomaxin, 2310003D02Rik, mXin beta, A530024P18Rik, Cmya3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241431
Homologene: 19388
Me3
Name: malic enzyme 3, NADP(+)-dependent, mitochondrial
Synonyms: B230207H15Rik, 1700020C08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 109264
HGNC: HGNC:6985
Homologene: 100773
Serpina3j
Name: serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3J
Synonyms: Gm4931, alpha-1 antiproteinase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 238395
HGNC: HGNC:16
Homologene: 120222
Hs2st1
Name: heparan sulfate 2-O-sulfotransferase 1
Synonyms: Hs2st
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 23908
HGNC: HGNC:5193
Homologene: 8025
Exoc3l
Name: exocyst complex component 3-like
Synonyms: C730015A04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 277978
Homologene: 18629
Tdrd5
Name: tudor domain containing 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 214575
Homologene: 18312
H1f8
Name: H1.8 linker histone
Synonyms: H1oo, H1foo, H1-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 171506
Homologene: 51377
Fshr
Name: follicle stimulating hormone receptor
Synonyms: follicle-stimulating hormone receptor, FSH-R, Follitropin receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 14309
VEGA: 17
HGNC: HGNC:3969
Homologene: 117
Rbm11
Name: RNA binding motif protein 11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 224344
HGNC: HGNC:9897
Homologene: 16988
Olfr1331
Name: olfactory receptor 1331
Synonyms: MOR259-3P, GA_x6K02T2QD9B-18670866-18669913
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 258159
Homologene: 134082
Lmntd2
Name: lamin tail domain containing 2
Synonyms: 1600016N20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 72000
Homologene: 104159
Gmpr
Name: guanosine monophosphate reductase
Synonyms: 2310004P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 66355
HGNC: HGNC:4376
Homologene: 5009
Zfp114
Name: zinc finger protein 114
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 232966
Trim61
Name: tripartite motif-containing 61
Synonyms: E330039K03Rik, 2czf61, Rnf35
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 260296
Tdpoz3
Name: TD and POZ domain containing 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 399674
Homologene: 128308
Plch1
Name: phospholipase C, eta 1
Synonyms: Plcl3, PLCeta1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 269437
Homologene: 88833
Gm5501
Name: predicted gene 5501
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 433161
Brsk2
Name: BR serine/threonine kinase 2
Synonyms: 4833424K13Rik, SAD-A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 75770
Homologene: 123829
Olfr894
Name: olfactory receptor 894
Synonyms: MOR170-5, GA_x6K02T2PVTD-31898993-31899934
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258868
Vmn1r183
Name: vomeronasal 1 receptor 183
Synonyms: LOC209824, V1rd15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 209824
Homologene: 104166
Dpysl2
Name: dihydropyrimidinase-like 2
Synonyms: DRP2, Ulip2, TOAD-64, Crmp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 12934
HGNC: HGNC:3014
Homologene: 74392
St6gal2
Name: beta galactoside alpha 2,6 sialyltransferase 2
Synonyms: ST6Gal II, C230064G14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 240119
Homologene: 13052
Gnat3
Name: guanine nucleotide binding protein, alpha transducing 3
Synonyms: alpha-gustducin, Ggust, Gtn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 242851
Homologene: 24284
Kcnj15
Name: potassium inwardly-rectifying channel, subfamily J, member 15
Synonyms: 4930414N08Rik, IRKK, Kir4.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 16516
HGNC: HGNC:6261
Homologene: 1690
Krtap4-1
Name: keratin associated protein 4-1
Synonyms: A030010K20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 665891
H2-Q4
Name: histocompatibility 2, Q region locus 4
Synonyms: Qa-4, H2-Gs10, H-2Q4, Qb-1, Qb1, Qa4, Qat-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 15015
HGNC: HGNC:4931
Homologene: 128352
Fam229a
Name: family with sequence similarity 229, member A
Synonyms: 1700125D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 68233
Homologene: 47789
Scg5
Name: secretogranin V
Synonyms: Sgne-1, 7B2, Sgne1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20394
Homologene: 37722
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 20,540,305 bp
  • T to A, chromosome 1 at 87,676,385 bp
  • T to A, chromosome 1 at 118,669,476 bp
  • G to A, chromosome 1 at 156,300,778 bp
  • T to A, chromosome 2 at 67,511,669 bp
  • T to C, chromosome 2 at 113,791,885 bp
  • T to C, chromosome 2 at 160,687,749 bp
  • G to A, chromosome 3 at 63,767,623 bp
  • T to C, chromosome 3 at 93,826,909 bp
  • T to C, chromosome 3 at 144,434,628 bp
  • C to T, chromosome 4 at 46,382,647 bp
  • T to C, chromosome 4 at 118,868,982 bp
  • T to A, chromosome 4 at 120,541,896 bp
  • A to G, chromosome 4 at 129,491,411 bp
  • G to A, chromosome 5 at 18,003,894 bp
  • A to G, chromosome 6 at 115,948,796 bp
  • A to T, chromosome 7 at 3,717,638 bp
  • T to C, chromosome 7 at 24,055,572 bp
  • T to C, chromosome 7 at 24,181,042 bp
  • A to G, chromosome 7 at 80,081,386 bp
  • T to C, chromosome 7 at 89,833,690 bp
  • C to T, chromosome 7 at 141,211,204 bp
  • T to C, chromosome 7 at 141,998,418 bp
  • A to G, chromosome 8 at 65,013,317 bp
  • C to T, chromosome 8 at 105,290,917 bp
  • T to C, chromosome 9 at 38,218,835 bp
  • T to A, chromosome 9 at 59,895,283 bp
  • G to T, chromosome 9 at 104,011,730 bp
  • C to A, chromosome 9 at 113,906,105 bp
  • A to G, chromosome 10 at 61,867,525 bp
  • A to G, chromosome 11 at 53,570,614 bp
  • A to T, chromosome 11 at 76,468,735 bp
  • G to T, chromosome 11 at 80,484,261 bp
  • A to G, chromosome 11 at 99,628,157 bp
  • C to T, chromosome 11 at 117,723,529 bp
  • A to T, chromosome 12 at 104,319,657 bp
  • A to G, chromosome 13 at 45,529,747 bp
  • A to G, chromosome 14 at 66,824,431 bp
  • G to A, chromosome 16 at 75,593,044 bp
  • A to G, chromosome 16 at 95,296,509 bp
  • A to G, chromosome 17 at 24,471,341 bp
  • T to G, chromosome 17 at 35,379,690 bp
  • A to G, chromosome 17 at 55,496,323 bp
  • A to G, chromosome 17 at 74,611,175 bp
  • A to G, chromosome 17 at 74,638,409 bp
  • C to T, chromosome 17 at 88,985,534 bp
  • A to G, chromosome 18 at 9,917,267 bp
  • T to C, chromosome X at 105,879,917 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3928 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040823-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.