Strain Name:
C57BL/6J-MtgxR3810Btlr/Mmmh
Stock Number:
040880-MU
Citation ID:
RRID:MMRRC_040880-MU
Other Names:
R3810 (G1), C57BL/6J-MtgxR3810Btlr
Major Collection:

Gene Information

Ahcyl2
Name: S-adenosylhomocysteine hydrolase-like 2
Synonyms: 4631427C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 74340
Homologene: 69337
Neurl4
Name: neuralized E3 ubiquitin protein ligase 4
Synonyms: 0610025P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216860
Homologene: 13029
Dock6
Name: dedicator of cytokinesis 6
Synonyms: C330023D02Rik, 4931431C02Rik, 2410095B20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 319899
VEGA: 9
Homologene: 83291
Psmd1
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
Synonyms: P112, S1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 70247
HGNC: HGNC:9554
Homologene: 2100
Trpc4ap
Name: transient receptor potential cation channel, subfamily C, member 4 associated protein
Synonyms: 4833429F06Rik, D2Ertd113e, Trrp4ap, Trp4-associated protein TAP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 56407
Homologene: 9224
Ctbp1
Name: C-terminal binding protein 1
Synonyms: D4S115h, D5H4S115E, CtBP1-L, CtBP1-S, CtBP3/BARS, D5H4S115, BARS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 13016
HGNC: HGNC:2494
Homologene: 1015
Orc6
Name: origin recognition complex, subunit 6
Synonyms: Orc6l, 6720420I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 56452
Homologene: 8635
Rbbp5
Name: retinoblastoma binding protein 5, histone lysine methyltransferase complex subunit
Synonyms: 4933411J24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 213464
HGNC: HGNC:9888
Homologene: 3709
Uvrag
Name: UV radiation resistance associated gene
Synonyms: 9530039D02Rik, Uvragl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 78610
Homologene: 31150
Vim
Name: vimentin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22352
Homologene: 2538
Secisbp2l
Name: SECIS binding protein 2-like
Synonyms: 3110001I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 70354
Homologene: 18923
Oas1d
Name: 2'-5' oligoadenylate synthetase 1D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100535
HGNC: HGNC:8086
Homologene: 110815
Gm9847
Name: predicted pseudogene 9847
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 100043256
VEGA: 12
HGNC: null
Homologene: null
Dapk1
Name: death associated protein kinase 1
Synonyms: 2810425C21Rik, 2310039H24Rik, DAP-Kinase, D13Ucla1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 69635
VEGA: 13
HGNC: HGNC:2674
Homologene: 3626
Metap2
Name: methionine aminopeptidase 2
Synonyms: eIF-2-associated p67, 4930584B20Rik, p67, A930035J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 56307
Homologene: 4981
Txndc5
Name: thioredoxin domain containing 5
Synonyms: PC-TRP, ERp46
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 105245
Homologene: 11125
Pcdh12
Name: protocadherin 12
Synonyms: vascular endothelial cadherin-2, VE-cadherin-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 53601
HGNC: HGNC:8657
Homologene: 9574
Entpd3
Name: ectonucleoside triphosphate diphosphohydrolase 3
Synonyms: HB6, Cd39l3, NTPDase-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 215446
HGNC: HGNC:3365
Homologene: 68171
Hivep2
Name: human immunodeficiency virus type I enhancer binding protein 2
Synonyms: MIBP1, Gm20114, Shn-2, Schnurri-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 15273
HGNC: HGNC:4921
Homologene: 4900
Aadat
Name: aminoadipate aminotransferase
Synonyms: mKat-2, Kyat2, Kat2, KATII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 23923
Homologene: 56540
AC225448.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
Bpifb2
Name: BPI fold containing family B, member 2
Synonyms: 2310034L21Rik, Bpil1, 2310069A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 66557
Homologene: 11884
Agbl3
Name: ATP/GTP binding protein-like 3
Synonyms: 4930431N21Rik, Ccp3, 2900053G10Rik, 6530406M24Rik, Ccp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 76223
Homologene: 35330
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: MUC5, MUC9, 2300002I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Pls1
Name: plastin 1 (I-isoform)
Synonyms: I-fimbrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 102502
HGNC: HGNC:9090
Homologene: 68270
Ttc21b
Name: tetratricopeptide repeat domain 21B
Synonyms: aln, Thm1, line 158, 2410066K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 73668
Homologene: 57006
AC165146.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
Top2b
Name: topoisomerase (DNA) II beta
Synonyms: Top-2, D230016L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 21974
Homologene: 134711
Plekha6
Name: pleckstrin homology domain containing, family A member 6
Synonyms: Pepp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 240753
Homologene: 135779
Has1
Name: hyaluronan synthase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 15116
VEGA: 17
HGNC: HGNC:4818
Homologene: 1165
D130040H23Rik
Name: RIKEN cDNA D130040H23 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 211135
HGNC: null
Homologene: 138403
Klhl35
Name: kelch-like 35
Synonyms: 2810406K13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 72184
Homologene: 27849
Olfr1143
Name: olfactory receptor 1143
Synonyms: GA_x6K02T2Q125-49303473-49304405, MOR177-14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258290
HGNC: null
Homologene: 74079
Mrgpra9
Name: MAS-related GPR, member A9
Synonyms: EG668725, MrgA9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 668725
Homologene: 79615
Kcnd3
Name: potassium voltage-gated channel, Shal-related family, member 3
Synonyms: potassium channel Kv4.3M, Kv4.3, potassium channel Kv4.3L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 56543
HGNC: HGNC:6239
Homologene: 21036
H2-Q6
Name: histocompatibility 2, Q region locus 6
Synonyms: H-2Q6, Qa-6, 0610037M15Rik, Qa6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 110557
HGNC: HGNC:4931
Homologene: 128352
Olfr1255
Name: olfactory receptor 1255
Synonyms: MOR232-4, GA_x6K02T2Q125-51257221-51258135
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258979
Homologene: 82298
Olfr1152
Name: olfactory receptor 1152
Synonyms: GA_x6K02T2Q125-49372426-49373358, MOR177-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258103
HGNC: null
Homologene: 79357
Olfr1232
Name: olfactory receptor 1232
Synonyms: GA_x6K02T2Q125-50770831-50769896, MOR233-18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258320
HGNC: null
Homologene: 74068
Tas2r130
Name: taste receptor, type 2, member 130
Synonyms: STC 7-4, T2R30, Tas2r30, mt2r42
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 387355
Homologene: 41536
Abhd6
Name: abhydrolase domain containing 6
Synonyms: 0610041D24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 66082
VEGA: 14
Homologene: 23246
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 86,132,715 bp
  • T to C, chromosome 1 at 132,492,587 bp
  • A to G, chromosome 1 at 133,273,979 bp
  • T to C, chromosome 2 at 13,578,752 bp
  • C to T, chromosome 2 at 66,252,233 bp
  • C to T, chromosome 2 at 87,803,052 bp
  • T to A, chromosome 2 at 87,868,401 bp
  • G to A, chromosome 2 at 89,325,754 bp
  • T to A, chromosome 2 at 89,817,051 bp
  • C to T, chromosome 2 at 125,740,737 bp
  • T to A, chromosome 2 at 153,891,951 bp
  • T to A, chromosome 2 at 155,643,435 bp
  • C to T, chromosome 3 at 105,658,766 bp
  • A to G, chromosome 5 at 33,267,045 bp
  • A to T, chromosome 5 at 120,914,986 bp
  • A to G, chromosome 6 at 29,891,261 bp
  • G to T, chromosome 6 at 34,799,729 bp
  • A to G, chromosome 6 at 131,630,829 bp
  • T to A, chromosome 7 at 47,235,779 bp
  • A to G, chromosome 7 at 98,979,712 bp
  • A to G, chromosome 7 at 99,470,241 bp
  • T to C, chromosome 7 at 141,864,126 bp
  • G to T, chromosome 8 at 60,518,518 bp
  • T to A, chromosome 8 at 69,302,370 bp
  • T to A, chromosome 8 at 85,299,984 bp
  • T to C, chromosome 9 at 21,801,577 bp
  • T to A, chromosome 9 at 95,786,920 bp
  • A to G, chromosome 9 at 120,562,002 bp
  • A to G, chromosome 10 at 14,130,357 bp
  • A to T, chromosome 10 at 93,870,164 bp
  • A to G, chromosome 11 at 69,904,033 bp
  • T to C, chromosome 12 at 14,495,147 bp
  • T to C, chromosome 13 at 38,523,405 bp
  • T to C, chromosome 13 at 60,760,689 bp
  • T to A, chromosome 14 at 8,045,603 bp
  • T to G, chromosome 14 at 16,409,189 bp
  • A to T, chromosome 14 at 19,402,398 bp
  • T to C, chromosome 17 at 17,847,560 bp
  • A to G, chromosome 17 at 35,425,781 bp
  • G to A, chromosome 17 at 94,876,710 bp
  • T to C, chromosome 18 at 38,281,237 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3810 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040880-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.