Strain Name:
C57BL/6J-MtgxR3856Btlr/Mmmh
Stock Number:
040902-MU
Citation ID:
RRID:MMRRC_040902-MU
Other Names:
R3856 (G1), C57BL/6J-MtgxR3856Btlr
Major Collection:

Gene Information

Ank2
Name: ankyrin 2, brain
Synonyms: Ank-2, ankyrin B, Gm4392, Ankyrin-B, Ankyrin-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 109676
HGNC: HGNC:493
Cacna1h
Name: calcium channel, voltage-dependent, T type, alpha 1H subunit
Synonyms: T-type Cav3.2, alpha13.2, Cav3.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 58226
HGNC: HGNC:1395
Homologene: 56913
Gpr82
Name: G protein-coupled receptor 82
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 319200
HGNC: HGNC:4533
Homologene: 36824
Sgsm1
Name: small G protein signaling modulator 1
Synonyms: 2410098H20Rik, Rutbc2, D5Bwg1524e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 52850
Homologene: 64485
Cnst
Name: consortin, connexin sorting protein
Synonyms: 9630058J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226744
Homologene: 17139
Cep131
Name: centrosomal protein 131
Synonyms: Azi1, AZ1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12009
Homologene: 7638
Ppp1r12a
Name: protein phosphatase 1, regulatory subunit 12A
Synonyms: 5730577I22Rik, 1200015F06Rik, Mypt1, D10Ertd625e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 17931
VEGA: 10
HGNC: HGNC:7618
Homologene: 1855
Hk2
Name: hexokinase 2
Synonyms: HKII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 15277
HGNC: HGNC:4923
Homologene: 37273
Ap3d1
Name: adaptor-related protein complex 3, delta 1 subunit
Synonyms: mBLVR1, Bolvr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 11776
VEGA: 10
HGNC: HGNC:568
Homologene: 2926
Ccdc60
Name: coiled-coil domain containing 60
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 269693
Homologene: 18624
Dffa
Name: DNA fragmentation factor, alpha subunit
Synonyms: A330085O09Rik, Dff45, ICAD-L, ICAD-S, DFF35
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13347
HGNC: HGNC:2772
Homologene: 3240
Arhgef1
Name: Rho guanine nucleotide exchange factor (GEF) 1
Synonyms: Lsc, Lbcl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16801
HGNC: HGNC:681
Homologene: 3454
Apex1
Name: apurinic/apyrimidinic endonuclease 1
Synonyms: Ref-1, HAP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 11792
HGNC: HGNC:587
Homologene: 1241
Pcnx3
Name: pecanex homolog 3
Synonyms: Pcnxl3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 104401
Homologene: 17000
Nhlrc2
Name: NHL repeat containing 2
Synonyms: 1200003G01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66866
VEGA: 19
Homologene: 12048
Crtc2
Name: CREB regulated transcription coactivator 2
Synonyms: 4632407F12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 74343
Homologene: 18765
Usp54
Name: ubiquitin specific peptidase 54
Synonyms: 4930429G18Rik, C030002J06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 78787
Homologene: 90902
Prmt9
Name: protein arginine methyltransferase 9
Synonyms: Prmt10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 102182
Homologene: 16298
Dnajc16
Name: DnaJ heat shock protein family (Hsp40) member C16
Synonyms: 2900037O03Rik, 4732437J24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 214063
Homologene: 45414
Eml5
Name: echinoderm microtubule associated protein like 5
Synonyms: C130068M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 319670
VEGA: 12
Homologene: 26807
Kdm4a
Name: lysine (K)-specific demethylase 4A
Synonyms: JHDM3A, Jmjd2a, D4Ertd222e, Jmjd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230674
Homologene: 27780
Scn2b
Name: sodium channel, voltage-gated, type II, beta
Synonyms: LOC214238, 2810451E09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 72821
VEGA: 9
Homologene: 3373
Trim55
Name: tripartite motif-containing 55
Synonyms: Murf2, D830041C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 381485
Homologene: 13205
Sall3
Name: spalt like transcription factor 3
Synonyms: B130022O04Rik, Salt, Msal-1, Msal, Spalt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 20689
VEGA: 18
Homologene: 18142
Adgrf5
Name: adhesion G protein-coupled receptor F5
Synonyms: Gpr116, 8430401C09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224792
VEGA: 17
Homologene: 9065
Myh13
Name: myosin, heavy polypeptide 13, skeletal muscle
Synonyms: EO Myosin, MyHC-eo, extraocular myosin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 544791
HGNC: HGNC:7571
Homologene: 55780
Ush2a
Name: usherin
Synonyms: Ushrn, A930011D15Rik, Ush2a, LOC269160, MUSH2A, A930037M10Rik, LOC381317
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22283
Homologene: 66151
Atp1a3
Name: ATPase, Na+/K+ transporting, alpha 3 polypeptide
Synonyms: Atpa-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232975
HGNC: HGNC:801
Homologene: 113729
Rnf213
Name: ring finger protein 213
Synonyms: D11Ertd759e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 672511
Homologene: 45439
H2-M10.6
Name: histocompatibility 2, M region locus 10.6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 399549
Homologene: 117973
Slc13a4
Name: solute carrier family 13 (sodium/sulfate symporters), member 4
Synonyms: SUT-1, SUT1, 9630060C05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243755
Homologene: 69125
F12
Name: coagulation factor XII (Hageman factor)
Synonyms: FXII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 58992
HGNC: HGNC:3530
Homologene: 425
Acod1
Name: aconitate decarboxylase 1
Synonyms: Irg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 16365
Homologene: 35405
Slc8a1
Name: solute carrier family 8 (sodium/calcium exchanger), member 1
Synonyms: Ncx1, D930008O12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20541
VEGA: 17
Homologene: 69090
Frmpd1
Name: FERM and PDZ domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 666060
Homologene: 8939
Spag17
Name: sperm associated antigen 17
Synonyms: PF6, 4931427F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 74362
Homologene: 52601
Zfp735
Name: zinc finger protein 735
Synonyms: 1700012C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 76390
Homologene: 88945
Kctd1
Name: potassium channel tetramerisation domain containing 1
Synonyms: 4933402K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 106931
VEGA: 18
Homologene: 65999
Aox4
Name: aldehyde oxidase 4
Synonyms: 2310003G12Rik, AOH2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71872
Homologene: 70273
Atxn7l1
Name: ataxin 7-like 1
Synonyms: Atxn7l4, 2810423G08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 380753
Homologene: 53366
Hspa4l
Name: heat shock protein 4 like
Synonyms: Osp94, APG-1, 94kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18415
Homologene: 22610
Idi1
Name: isopentenyl-diphosphate delta isomerase
Synonyms: 4832416K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 319554
HGNC: HGNC:5387
Homologene: 3315
Atxn7l3
Name: ataxin 7-like 3
Synonyms: E030022H21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217218
Homologene: 35401
Galnt7
Name: polypeptide N-acetylgalactosaminyltransferase 7
Synonyms: ppGaNTase-T7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 108150
HGNC: HGNC:4129
Homologene: 9685
Vmn1r189
Name: vomeronasal 1 receptor 189
Synonyms: V1rh2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 252906
Homologene: 110880
Eef2k
Name: eukaryotic elongation factor-2 kinase
Synonyms: eEF-2K
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13631
Homologene: 7299
Gm2128
Name: predicted gene 2128
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100039269
Homologene: 45597
Fbxo40
Name: F-box protein 40
Synonyms: 9830003A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 207215
Homologene: 9459
Olfr608
Name: olfactory receptor 608
Synonyms: GA_x6K02T2PBJ9-6191595-6192545, MOR26-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258751
Nt5c2
Name: 5'-nucleotidase, cytosolic II
Synonyms: NT5B, PNT5, cN-II
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 76952
HGNC: HGNC:8022
Homologene: 8158
Gadd45a
Name: growth arrest and DNA-damage-inducible 45 alpha
Synonyms: Ddit1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 13197
HGNC: HGNC:4095
Homologene: 1449
Gpr171
Name: G protein-coupled receptor 171
Synonyms: F730001G15Rik, H963
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229323
Homologene: 36330
Fxyd1
Name: FXYD domain-containing ion transport regulator 1
Synonyms: 0610012C17Rik, phospholemman, PML, PLM, 1110006M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56188
HGNC: HGNC:4025
Homologene: 3691
Pudp
Name: pseudouridine 5'-phosphatase
Synonyms: 1700121L12Rik, Hdhd1a, GS1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 67365
VEGA: 18
Homologene: 8093
Ctsr
Name: cathepsin R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 56835
VEGA: 13
Homologene: 75127
Fam43b
Name: family with sequence similarity 43, member B
Synonyms: OTTMUSG00000009974
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 625638
Homologene: 45810
Pbp2
Name: phosphatidylethanolamine binding protein 2
Synonyms: Pebp-2, 1700023A18Rik, Pebp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 76400
Homologene: 135930
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 58,253,934 bp
  • C to T, chromosome 1 at 179,579,714 bp
  • C to A, chromosome 1 at 188,626,567 bp
  • T to C, chromosome 3 at 19,672,956 bp
  • C to A, chromosome 3 at 40,785,389 bp
  • T to C, chromosome 3 at 59,098,085 bp
  • G to T, chromosome 3 at 90,262,570 bp
  • A to T, chromosome 3 at 100,106,759 bp
  • T to C, chromosome 3 at 126,929,844 bp
  • T to C, chromosome 4 at 45,283,698 bp
  • C to T, chromosome 4 at 118,153,231 bp
  • G to C, chromosome 4 at 138,395,098 bp
  • G to A, chromosome 4 at 141,763,653 bp
  • A to T, chromosome 4 at 149,104,251 bp
  • A to G, chromosome 5 at 113,263,259 bp
  • A to C, chromosome 5 at 116,172,455 bp
  • C to A, chromosome 6 at 35,271,604 bp
  • C to T, chromosome 6 at 67,037,005 bp
  • T to C, chromosome 6 at 82,736,676 bp
  • A to G, chromosome 6 at 135,310,145 bp
  • G to A, chromosome 7 at 24,919,272 bp
  • A to G, chromosome 7 at 24,989,979 bp
  • G to A, chromosome 7 at 31,053,878 bp
  • G to A, chromosome 7 at 41,157,835 bp
  • T to A, chromosome 7 at 103,470,660 bp
  • T to A, chromosome 7 at 120,899,371 bp
  • T to C, chromosome 8 at 57,532,624 bp
  • G to A, chromosome 8 at 77,568,265 bp
  • A to G, chromosome 9 at 45,125,461 bp
  • A to G, chromosome 10 at 80,712,185 bp
  • T to C, chromosome 10 at 108,253,501 bp
  • T to C, chromosome 11 at 67,353,759 bp
  • T to C, chromosome 11 at 73,711,456 bp
  • T to C, chromosome 11 at 102,293,903 bp
  • T to C, chromosome 11 at 119,480,939 bp
  • G to A, chromosome 11 at 120,067,185 bp
  • A to G, chromosome 12 at 33,367,600 bp
  • T to C, chromosome 12 at 98,816,024 bp
  • G to T, chromosome 13 at 8,885,932 bp
  • A to T, chromosome 13 at 22,102,269 bp
  • G to A, chromosome 13 at 55,421,222 bp
  • A to T, chromosome 13 at 61,161,936 bp
  • C to A, chromosome 14 at 20,588,420 bp
  • A to G, chromosome 14 at 50,926,257 bp
  • T to C, chromosome 14 at 103,055,446 bp
  • A to T, chromosome 16 at 36,969,083 bp
  • T to C, chromosome 17 at 25,392,453 bp
  • T to A, chromosome 17 at 36,812,504 bp
  • A to T, chromosome 17 at 43,447,036 bp
  • T to C, chromosome 17 at 81,648,374 bp
  • A to G, chromosome 18 at 15,007,883 bp
  • T to C, chromosome 18 at 50,568,053 bp
  • G to A, chromosome 18 at 80,972,502 bp
  • G to T, chromosome 19 at 5,678,967 bp
  • A to G, chromosome 19 at 46,896,518 bp
  • T to C, chromosome 19 at 56,588,271 bp
  • A to T, chromosome X at 13,665,338 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3856 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040902-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.