Strain Name:
C57BL/6J-MtgxR4167Btlr/Mmmh
Stock Number:
041008-MU
Citation ID:
RRID:MMRRC_041008-MU
Other Names:
R4167 (G1), C57BL/6J-MtgxR4167Btlr
Major Collection:

Gene Information

Plcd3
Name: phospholipase C, delta 3
Synonyms: 2610205J15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 72469
HGNC: HGNC:9061
Homologene: 14858
Kat14
Name: lysine acetyltransferase 14
Synonyms: 2510008M08Rik, D2Ertd473e, D2Wsu131e, ATAC2, Csrp2bp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228714
Homologene: 10745
Dcp2
Name: decapping mRNA 2
Synonyms: 2410015D23Rik, 5730537H01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 70640
Homologene: 13968
Rraga
Name: Ras-related GTP binding A
Synonyms: FIP-1, 1300010C19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 68441
Homologene: 68522
Scmh1
Name: sex comb on midleg homolog 1
Synonyms: Scml3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 29871
Homologene: 32146
Plxdc2
Name: plexin domain containing 2
Synonyms: 1200007L24Rik, Tem7r, 5430431D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67448
Homologene: 41666
Krt74
Name: keratin 74
Synonyms: Kb37
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 406222
VEGA: 15
Casp6
Name: caspase 6
Synonyms: Mch2, mCASP-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12368
HGNC: HGNC:1507
Homologene: 37455
Rnf213
Name: ring finger protein 213
Synonyms: D11Ertd759e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 672511
Homologene: 45439
Lrp12
Name: low density lipoprotein-related protein 12
Synonyms: C820005L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239393
Homologene: 8385
Pcdhgb8
Name: protocadherin gamma subfamily B, 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93705
Homologene: 81868
Man2c1
Name: mannosidase, alpha, class 2C, member 1
Synonyms: 1110025H24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 73744
HGNC: HGNC:6827
Homologene: 4887
Cdh16
Name: cadherin 16
Synonyms: KSP-cadherin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12556
HGNC: HGNC:1755
Homologene: 2997
Gabrb2
Name: gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
Synonyms: Gabrb-2, C030021G16Rik, C030002O17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14401
HGNC: HGNC:4082
Homologene: 7327
Naip1
Name: NLR family, apoptosis inhibitory protein 1
Synonyms: D13Lsd1, Naip, Birc1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17940
VEGA: 13
HGNC: HGNC:7634
Homologene: 113589
Kcng1
Name: potassium voltage-gated channel, subfamily G, member 1
Synonyms: OTTMUSG00000016048
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241794
HGNC: HGNC:6248
Homologene: 20515
Glyctk
Name: glycerate kinase
Synonyms: 6230410P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235582
Homologene: 14738
Slc9a9
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 9
Synonyms: 5730527A11Rik, Nhe9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 331004
Homologene: 69753
Elk3
Name: ELK3, member of ETS oncogene family
Synonyms: Erp, Sap-2, Net, D430049E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 13713
HGNC: HGNC:3325
Homologene: 3833
Olfr111
Name: olfactory receptor 111
Synonyms: MOR249-1P, GA_x6K02T2PSCP-1989071-1990024
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 545205
Homologene: 73968
Mindy4
Name: MINDY lysine 48 deubiquitinase 4
Synonyms: LOC384387, C330043M08Rik, Fam188b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330323
Homologene: 49991
Oog2
Name: oogenesin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 381570
Homologene: 77858
Ndufaf7
Name: NADH:ubiquinone oxidoreductase complex assembly factor 7
Synonyms: 2410091C18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 73694
VEGA: 17
Homologene: 12508
Snx20
Name: sorting nexin 20
Synonyms: 9130017C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 71607
Homologene: 12399
Cd200r3
Name: CD200 receptor 3
Synonyms: 4733401I18Rik, mCD200RLb, 4833409J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 74603
Abhd16a
Name: abhydrolase domain containing 16A
Synonyms: Bat5, NG26, D17H6S82E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 193742
Homologene: 10904
Zfp128
Name: zinc finger protein 128
Synonyms: mZnf8, 9630016P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243833
Homologene: 10889
Fam78b
Name: family with sequence similarity 78, member B
Synonyms: C030020L09Rik, C030014K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226610
Homologene: 18451
Olfr1167
Name: olfactory receptor 1167
Synonyms: GA_x6K02T2Q125-49641892-49640942, MOR174-16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258291
Homologene: 138307
Nppb
Name: natriuretic peptide type B
Synonyms: BNP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18158
HGNC: HGNC:7940
Homologene: 49182
Hmgb1-ps7
Name: high-mobility group high mobility group box 1, pseudogene 7
Synonyms: EG434174, Hmg1l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 434174
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 167,001,732 bp
  • A to G, chromosome 2 at 16,565,385 bp
  • T to C, chromosome 2 at 88,149,845 bp
  • A to G, chromosome 2 at 144,394,110 bp
  • T to A, chromosome 2 at 168,262,697 bp
  • A to G, chromosome 3 at 129,913,344 bp
  • T to C, chromosome 4 at 86,576,067 bp
  • T to C, chromosome 4 at 120,529,276 bp
  • A to T, chromosome 4 at 144,196,212 bp
  • T to A, chromosome 4 at 147,986,974 bp
  • G to A, chromosome 6 at 55,224,346 bp
  • A to G, chromosome 7 at 12,890,362 bp
  • A to G, chromosome 7 at 42,021,308 bp
  • C to T, chromosome 8 at 88,627,385 bp
  • A to G, chromosome 8 at 104,617,730 bp
  • A to G, chromosome 9 at 57,138,026 bp
  • A to G, chromosome 9 at 95,228,899 bp
  • G to T, chromosome 9 at 106,157,762 bp
  • A to G, chromosome 10 at 93,265,335 bp
  • A to T, chromosome 11 at 42,421,328 bp
  • A to T, chromosome 11 at 103,078,464 bp
  • A to G, chromosome 11 at 119,441,243 bp
  • C to T, chromosome 13 at 100,444,286 bp
  • T to C, chromosome 15 at 39,885,013 bp
  • A to G, chromosome 15 at 101,758,869 bp
  • T to A, chromosome 16 at 44,954,189 bp
  • A to G, chromosome 17 at 35,100,361 bp
  • T to C, chromosome 17 at 37,530,006 bp
  • G to A, chromosome 17 at 78,944,986 bp
  • T to G, chromosome 18 at 37,762,543 bp
  • T to A, chromosome 18 at 44,395,967 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4167 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
041008-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.