Strain Name:
C57BL/6J-MtgxR4231Btlr/Mmmh
Stock Number:
041050-MU
Citation ID:
RRID:MMRRC_041050-MU
Other Names:
R4231 (G1), C57BL/6J-MtgxR4231Btlr
Major Collection:

Gene Information

Myo5a
Name: myosin VA
Synonyms: 9630007J19Rik, MyoVA, flail, MVa, Myo5, Dbv
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 17918
HGNC: HGNC:7602
Homologene: 20100
Casp8
Name: caspase 8
Synonyms: Mch5, MACH, Caspase-8, FLICE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12370
HGNC: HGNC:1509
Homologene: 7657
Arhgef18
Name: rho/rac guanine nucleotide exchange factor (GEF) 18
Synonyms: A430078G23Rik, D030053O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 319493
Homologene: 32254
Senp2
Name: SUMO/sentrin specific peptidase 2
Synonyms: 2310007L05Rik, 4930538C18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 75826
VEGA: 16
Homologene: 11005
Kif20a
Name: kinesin family member 20A
Synonyms: Rabkinesin-6, Rab6kifl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 19348
VEGA: 18
HGNC: HGNC:9787
Homologene: 38093
Atg14
Name: autophagy related 14
Synonyms: Barkor, D14Ertd114e, D14Ertd436e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 100504663
VEGA: 14
Homologene: 45423
Ddx1
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 104721
VEGA: 12
HGNC: HGNC:2734
Homologene: 3627
Rps6kc1
Name: ribosomal protein S6 kinase polypeptide 1
Synonyms: B130003F20Rik, RPK118
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 320119
Homologene: 8244
Sart3
Name: squamous cell carcinoma antigen recognized by T cells 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 53890
Homologene: 40977
Xpo6
Name: exportin 6
Synonyms: C230091E20Rik, 2610005L19Rik, Ranbp20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 74204
Homologene: 12544
4932438A13Rik
Name: RIKEN cDNA 4932438A13 gene
Synonyms: FSA, Tweek
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229227
Homologene: 52105
Rnf216
Name: ring finger protein 216
Synonyms: 2810055G22Rik, UIP83, Ubce7ip1, F830018F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 108086
Homologene: 19442
Zbtb17
Name: zinc finger and BTB domain containing 17
Synonyms: Zfp100, mZ13, Miz1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 22642
Homologene: 2575
Slitrk6
Name: SLIT and NTRK-like family, member 6
Synonyms: 4832410J21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 239250
VEGA: 14
Homologene: 12986
Spc24
Name: SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
Synonyms: Spbc24, 2410030K01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 67629
VEGA: 9
Homologene: 12166
Scube1
Name: signal peptide, CUB domain, EGF-like 1
Synonyms: A630023E24Rik, 7330410C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 64706
Homologene: 11224
Scn10a
Name: sodium channel, voltage-gated, type X, alpha
Synonyms: Nav1.8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 20264
VEGA: 9
Homologene: 21300
Map3k1
Name: mitogen-activated protein kinase kinase kinase 1
Synonyms: Mekk, MEKK1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 26401
HGNC: HGNC:6848
Homologene: 8056
Tardbp
Name: TAR DNA binding protein
Synonyms: TDP-43, Tdp43, 1190002A23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230908
Homologene: 7221
Crip2
Name: cysteine rich protein 2
Synonyms: ESP1, 0610010I23Rik, Crp, Hlp, CRP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 68337
HGNC: HGNC:2361
Homologene: 133917
Kremen1
Name: kringle containing transmembrane protein 1
Synonyms: Krm1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 84035
Homologene: 12935
Jak3
Name: Janus kinase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 16453
HGNC: HGNC:6193
Homologene: 181
Nsun2
Name: NOL1/NOP2/Sun domain family member 2
Synonyms: Misu
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 28114
Homologene: 9817
Rfx7
Name: regulatory factor X, 7
Synonyms: D130086K05Rik, 2510005N23Rik, Rfxdc2, 9930116O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 319758
Homologene: 11275
Zfp599
Name: zinc finger protein 599
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235048
HGNC: null
Homologene: 138456
Zfhx2
Name: zinc finger homeobox 2
Synonyms: zfh-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 239102
Homologene: 52657
Plxna2
Name: plexin A2
Synonyms: 2810428A13Rik, PlexA2, Plxn2, OCT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18845
HGNC: HGNC:9100
Homologene: 56427
Nbas
Name: neuroblastoma amplified sequence
Synonyms: 4933425L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 71169
VEGA: 12
Homologene: 41073
Tgm3
Name: transglutaminase 3, E polypeptide
Synonyms: TG E, we
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 21818
Homologene: 20690
Akap6
Name: A kinase (PRKA) anchor protein 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 238161
VEGA: 12
HGNC: HGNC:376
Homologene: 3157
Irak2
Name: interleukin-1 receptor-associated kinase 2
Synonyms: 6330415L08Rik, IRAK-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 108960
HGNC: HGNC:6113
Homologene: 1207
Tex15
Name: testis expressed gene 15
Synonyms: 2210014E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 104271
Homologene: 12837
Pcdh7
Name: protocadherin 7
Synonyms: BH-protocadherin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 54216
HGNC: HGNC:8659
Homologene: 36101
Ptprq
Name: protein tyrosine phosphatase, receptor type, Q
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 237523
HGNC: HGNC:9679
Homologene: 83557
Nalcn
Name: sodium leak channel, non-selective
Synonyms: A530023G15Rik, Vgcnl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 338370
VEGA: 14
Homologene: 21832
Impg1
Name: interphotoreceptor matrix proteoglycan 1
Synonyms: A930015H12Rik, SPACR, IMP150
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 63859
HGNC: HGNC:6055
Homologene: 1201
Rin2
Name: Ras and Rab interactor 2
Synonyms: 4632403N06Rik, 2010003K16Rik, RASSF4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 74030
Homologene: 32430
Fscn1
Name: fascin actin-bundling protein 1
Synonyms: fascin-1, Fan1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 14086
Homologene: 48164
Ankar
Name: ankyrin and armadillo repeat containing
Synonyms: 4932422E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 319695
Homologene: 85163
Gm12887
Name: predicted gene 12887
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 666927
HGNC: null
Homologene: 111034
Aox3
Name: aldehyde oxidase 3
Synonyms: 1200011D03Rik, AOH1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 71724
Homologene: 90899
Olfr53
Name: olfactory receptor 53
Synonyms: MOR253-5, IE12, GA_x6K02T2PBJ9-42798103-42799038
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258962
HGNC: null
Homologene: 133678
Cd93
Name: CD93 antigen
Synonyms: AA4.1, Ly68, C1qr1, C1qrp, 6030404G09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17064
Homologene: 7823
Rufy4
Name: RUN and FYVE domain containing 4
Synonyms: F930048N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 435626
Homologene: 52359
Cacnb2
Name: calcium channel, voltage-dependent, beta 2 subunit
Synonyms: Cchb2, Cavbeta2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 12296
HGNC: HGNC:1402
Homologene: 75191
Rfx4
Name: regulatory factor X, 4 (influences HLA class II expression)
Synonyms: 4933412G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 71137
HGNC: HGNC:9985
Homologene: 31119
Crat
Name: carnitine acetyltransferase
Synonyms: CARAT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 12908
HGNC: HGNC:2342
Homologene: 598
Jmy
Name: junction-mediating and regulatory protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 57748
VEGA: 13
Homologene: 10955
Dtx3
Name: deltex 3, E3 ubiquitin ligase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 80904
Homologene: 12754
Sipa1
Name: signal-induced proliferation associated gene 1
Synonyms: SPA-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 20469
VEGA: 19
Homologene: 7940
Irgm2
Name: immunity-related GTPase family M member 2
Synonyms: Gtpi, Iigp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 54396
Homologene: 78363
Ip6k2
Name: inositol hexaphosphate kinase 2
Synonyms: Ihpk2, 1500005N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 76500
Homologene: 56929
Insyn2b
Name: inhibitory synaptic factor family member 2B
Synonyms: Fam196b, Gm6041
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 574403
VEGA: 11
Homologene: 107175
Setd7
Name: SET domain containing (lysine methyltransferase) 7
Synonyms: Set7, 1600028F23Rik, KMT7, Set7/9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 73251
Homologene: 12741
Dip2a
Name: disco interacting protein 2 homolog A
Synonyms: 4931420H10Rik, Dip2, Kiaa0184-hp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 64451
Homologene: 41012
Itgb6
Name: integrin beta 6
Synonyms: 4831415H04Rik, 2210409C20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16420
HGNC: HGNC:6161
Homologene: 685
Lrrc71
Name: leucine rich repeat containing 71
Synonyms: 4933430H15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 74485
Homologene: 83646
Wscd2
Name: WSC domain containing 2
Synonyms: C530024P05Rik, 4933413A10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 320916
Homologene: 35372
Prkar1b
Name: protein kinase, cAMP dependent regulatory, type I beta
Synonyms: RIbeta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 19085
HGNC: HGNC:9390
Homologene: 37665
Skint11
Name: selection and upkeep of intraepithelial T cells 11
Synonyms: A630098G03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230623
HGNC: null
Homologene: 136292
Aldh5a1
Name: aldhehyde dehydrogenase family 5, subfamily A1
Synonyms: SSADH, D630032B01Rik, 6330403E24Rik, OTTMUSG00000000613
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 214579
HGNC: HGNC:408
Homologene: 840
Nxpe4
Name: neurexophilin and PC-esterase domain family, member 4
Synonyms: D930028F11Rik, Fam55d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244853
VEGA: 9
Homologene: 83471
P2ry12
Name: purinergic receptor P2Y, G-protein coupled 12
Synonyms: P2Y12, 2900079B22Rik, 4921504D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 70839
Homologene: 11260
4930567H17Rik
Name: RIKEN cDNA 4930567H17 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 619303
HGNC: null
Homologene: 134521
Filip1l
Name: filamin A interacting protein 1-like
Synonyms: 4631422O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 78749
Homologene: 37121
Olfr849
Name: olfactory receptor 849
Synonyms: GA_x6K02T2PVTD-13176842-13177780, MOR151-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258520
HGNC: null
Homologene: 74179
Cox6b2
Name: cytochrome c oxidase subunit 6B2
Synonyms: 1700067P11Rik, COXVIB2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 333182
Homologene: 16948
Ajuba
Name: ajuba LIM protein
Synonyms: Jub
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 16475
VEGA: 14
Homologene: 7789
RP24-244I20.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
Olfr1293-ps
Name: olfactory receptor 1293, pseudogene
Synonyms: MOR245-24P, OTTMUSG00000015076, GA_x6K02T2Q125-72578807-72579745
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 623583
HGNC: null
Homologene: null
Gm26678
Name: predicted gene, 26678
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: null
VEGA: null
HGNC: null
Homologene: null
B430218F22Rik
Name: RIKEN cDNA B430218F22 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: null
VEGA: null
HGNC: null
Homologene: null
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 58,114,885 bp
  • T to C, chromosome 1 at 58,844,770 bp
  • T to C, chromosome 1 at 72,658,542 bp
  • T to C, chromosome 1 at 74,147,663 bp
  • A to G, chromosome 1 at 97,884,124 bp
  • A to G, chromosome 1 at 190,808,900 bp
  • C to T, chromosome 1 at 194,644,454 bp
  • A to G, chromosome 2 at 14,981,440 bp
  • T to C, chromosome 2 at 30,413,011 bp
  • A to T, chromosome 2 at 60,668,521 bp
  • C to T, chromosome 2 at 111,528,201 bp
  • A to T, chromosome 2 at 130,044,589 bp
  • C to T, chromosome 2 at 145,860,446 bp
  • A to T, chromosome 2 at 148,442,960 bp
  • C to T, chromosome 3 at 36,920,236 bp
  • T to C, chromosome 3 at 51,542,730 bp
  • T to C, chromosome 3 at 54,633,083 bp
  • T to G, chromosome 3 at 59,257,223 bp
  • A to G, chromosome 3 at 87,740,991 bp
  • C to A, chromosome 4 at 114,244,659 bp
  • A to T, chromosome 4 at 121,622,102 bp
  • C to T, chromosome 4 at 141,465,074 bp
  • T to C, chromosome 4 at 148,617,601 bp
  • G to A, chromosome 5 at 57,719,289 bp
  • A to G, chromosome 5 at 113,560,984 bp
  • A to G, chromosome 5 at 113,771,418 bp
  • A to G, chromosome 5 at 139,108,621 bp
  • T to C, chromosome 5 at 142,971,966 bp
  • A to T, chromosome 5 at 143,093,090 bp
  • A to G, chromosome 6 at 113,690,856 bp
  • T to C, chromosome 7 at 4,752,835 bp
  • T to C, chromosome 7 at 126,174,182 bp
  • T to C, chromosome 7 at 140,652,740 bp
  • T to C, chromosome 8 at 3,450,317 bp
  • T to C, chromosome 8 at 33,572,137 bp
  • T to A, chromosome 8 at 71,685,545 bp
  • T to A, chromosome 9 at 19,441,590 bp
  • T to C, chromosome 9 at 21,756,202 bp
  • T to A, chromosome 9 at 22,249,745 bp
  • A to T, chromosome 9 at 48,398,837 bp
  • A to T, chromosome 9 at 72,619,390 bp
  • A to G, chromosome 9 at 75,189,997 bp
  • A to G, chromosome 9 at 80,345,329 bp
  • G to A, chromosome 9 at 108,805,648 bp
  • G to T, chromosome 9 at 119,631,544 bp
  • G to A, chromosome 10 at 76,319,470 bp
  • A to T, chromosome 10 at 84,814,694 bp
  • A to T, chromosome 10 at 107,686,283 bp
  • A to G, chromosome 10 at 127,193,189 bp
  • G to A, chromosome 11 at 5,243,881 bp
  • A to T, chromosome 11 at 34,403,143 bp
  • C to T, chromosome 11 at 58,219,478 bp
  • C to T, chromosome 12 at 13,223,857 bp
  • A to G, chromosome 12 at 13,393,343 bp
  • A to T, chromosome 12 at 53,141,038 bp
  • T to C, chromosome 12 at 113,135,827 bp
  • C to T, chromosome 13 at 24,911,653 bp
  • A to G, chromosome 13 at 69,619,541 bp
  • G to T, chromosome 13 at 93,498,925 bp
  • T to C, chromosome 13 at 111,768,494 bp
  • T to C, chromosome 13 at 118,386,840 bp
  • T to C, chromosome 14 at 47,551,345 bp
  • T to C, chromosome 14 at 54,569,526 bp
  • A to G, chromosome 14 at 55,073,534 bp
  • A to T, chromosome 14 at 110,751,388 bp
  • T to A, chromosome 14 at 123,599,913 bp
  • C to T, chromosome 15 at 83,620,069 bp
  • T to C, chromosome 16 at 22,011,554 bp
  • T to C, chromosome 16 at 57,506,768 bp
  • A to G, chromosome 18 at 34,632,038 bp
  • A to T, chromosome 19 at 5,654,089 bp
  • C to T, chromosome X at 70,394,529 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4231 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
041050-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.