Strain Name:
C57BL/6J-MtgxR4422Btlr/Mmmh
Stock Number:
041695-MU
Citation ID:
RRID:MMRRC_041695-MU
Other Names:
R4422 (G1), C57BL/6J-MtgxR4422Btlr
Major Collection:

Gene Information

Hlcs
Name: holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase)
Synonyms: 410I21.SP6, D16Jhu34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 110948
VEGA: 16
HGNC: HGNC:4976
Homologene: 37302
Pik3r1
Name: phosphoinositide-3-kinase regulatory subunit 1
Synonyms: p85alpha, p50alpha, p55alpha, PI3K
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18708
HGNC: HGNC:8979
Homologene: 7889
Epha4
Name: Eph receptor A4
Synonyms: Sek, Sek1, Tyro1, Hek8, Cek8, 2900005C20Rik, rb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13838
HGNC: HGNC:3388
Homologene: 20933
Scarb1
Name: scavenger receptor class B, member 1
Synonyms: D5Ertd460e, Srb1, Cd36l1, Cla-1, SRBI, SR-BI, Hlb398, Hdlq1, Chohd1, Chohd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20778
HGNC: HGNC:1664
Homologene: 21132
Chrnb3
Name: cholinergic receptor, nicotinic, beta polypeptide 3
Synonyms: Acrb3, 5730417K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 108043
HGNC: HGNC:1963
Homologene: 36035
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: Acf7, Aclp7, trabeculin alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11426
Homologene: 136191
Tmem59l
Name: transmembrane protein 59-like
Synonyms: 5330410G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 67937
Homologene: 8104
Ppat
Name: phosphoribosyl pyrophosphate amidotransferase
Synonyms: 5730454C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231327
HGNC: HGNC:9238
Homologene: 68272
Wnk1
Name: WNK lysine deficient protein kinase 1
Synonyms: 6430573H23Rik, Prkwnk1, EG406236, Hsn2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232341
Homologene: 14253
Tyw5
Name: tRNA-yW synthesizing protein 5
Synonyms: 1110034B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68736
Homologene: 72085
Tnks2
Name: tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
Synonyms: 5430432P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 74493
Homologene: 11890
Mon2
Name: MON2 homolog, regulator of endosome to Golgi trafficking
Synonyms: SF21, 2610528O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67074
VEGA: 10
Homologene: 44309
Cct7
Name: chaperonin containing Tcp1, subunit 7 (eta)
Synonyms: Cctz, Ccth
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12468
HGNC: HGNC:1622
Homologene: 4694
Cenpf
Name: centromere protein F
Synonyms: 6530404A22Rik, Lek1, mitosin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 108000
HGNC: HGNC:1857
Homologene: 22969
Lamb2
Name: laminin, beta 2
Synonyms: Lamb-2, Lams, npht
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 16779
HGNC: HGNC:6487
Homologene: 1723
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 20191
VEGA: 13
Homologene: 37423
Mms22l
Name: MMS22-like, DNA repair protein
Synonyms: F730047E07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 212377
Homologene: 18874
Ldlr
Name: low density lipoprotein receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 16835
VEGA: 9
HGNC: HGNC:6547
Homologene: 55469
Rsbn1l
Name: round spermatid basic protein 1-like
Synonyms: 8430412F05Rik, C330002G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 242860
Homologene: 19435
Zfp871
Name: zinc finger protein 871
Synonyms: 9030612M13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 208292
Homologene: 138401
Syvn1
Name: synovial apoptosis inhibitor 1, synoviolin
Synonyms: Hrd1, 1200010C09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 74126
Homologene: 32700
Phf24
Name: PHD finger protein 24
Synonyms: N28178, GINIP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230085
Homologene: 18208
Reg4
Name: regenerating islet-derived family, member 4
Synonyms: RELP, 2010002L15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67709
Homologene: 41671
Gcnt2
Name: glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
Synonyms: IGnTC, IGnTB, IGnTA, 5330430K10Rik, IGnT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 14538
VEGA: 13
HGNC: HGNC:4204
Homologene: 41535
Lsr
Name: lipolysis stimulated lipoprotein receptor
Synonyms: Lisch7, ILDR3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 54135
Homologene: 9306
Dync1li1
Name: dynein cytoplasmic 1 light intermediate chain 1
Synonyms: LIC-1, 1110053F02Rik, Dnclic1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235661
VEGA: 9
Homologene: 9403
Dhx29
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 29
Synonyms: E130202M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218629
VEGA: 13
Homologene: 10387
Tpcn1
Name: two pore channel 1
Synonyms: 5730403B01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 252972
Homologene: 9905
Nrde2
Name: nrde-2 necessary for RNA interference, domain containing
Synonyms: 6720454P05Rik, BC002230
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217827
VEGA: 12
Homologene: 41213
Col4a4
Name: collagen, type IV, alpha 4
Synonyms: [a]4(IV), E130010M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12829
HGNC: HGNC:2206
Homologene: 20071
Grn
Name: granulin
Synonyms: acrogranulin, epithelin, PC cell-derived growth factor, progranulin, Pgrn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14824
HGNC: HGNC:4601
Homologene: 1577
Adamts13
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13
Synonyms: LOC279028, vWF-CP mRNA for von Willebrand factor-cleaving
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 279028
HGNC: HGNC:1366
Homologene: 16372
Capns2
Name: calpain, small subunit 2
Synonyms: 2310005G05Rik, 30K-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 69543
Homologene: 57167
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, 2810003K23Rik, Dnahcl1, Dnahc17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Fhod1
Name: formin homology 2 domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234686
Homologene: 136406
Plcb2
Name: phospholipase C, beta 2
Synonyms: B230205M18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18796
HGNC: HGNC:9055
Homologene: 20957
Akna
Name: AT-hook transcription factor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100182
Homologene: 49947
Cd19
Name: CD19 antigen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12478
HGNC: HGNC:1633
Homologene: 1341
Krt78
Name: keratin 78
Synonyms: 2310030B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 332131
VEGA: 15
Homologene: 65261
Vsig10
Name: V-set and immunoglobulin domain containing 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231668
Homologene: 10414
Psg21
Name: pregnancy-specific glycoprotein 21
Synonyms: cea8, 1600019C01Rik, 1600026N13Rik, 1600025N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 72242
Homologene: 110989
Fam120b
Name: family with sequence similarity 120, member B
Synonyms: CCPG, 4932442K08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 67544
VEGA: 17
Homologene: 13033
AW551984
Name: expressed sequence AW551984
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244810
Chrm3
Name: cholinergic receptor, muscarinic 3, cardiac
Synonyms: M3R, Chrm-3, muscarinic acetylcholine receptor 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 12671
HGNC: HGNC:1952
Homologene: 20191
Hip1r
Name: huntingtin interacting protein 1 related
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 29816
Homologene: 78348
Bank1
Name: B cell scaffold protein with ankyrin repeats 1
Synonyms: A530094C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 242248
Homologene: 9926
Prelid2
Name: PRELI domain containing 2
Synonyms: 1700003A01Rik, C330008K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 77619
VEGA: 18
Homologene: 45749
Thegl
Name: theg spermatid protein like
Synonyms: 1700023E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71868
Homologene: 128474
Itih4
Name: inter alpha-trypsin inhibitor, heavy chain 4
Synonyms: Itih-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 16427
HGNC: HGNC:6169
Homologene: 1670
Cep44
Name: centrosomal protein 44
Synonyms: 4933440G23Rik, BC088983
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 382010
Homologene: 12738
Olfr606
Name: olfactory receptor 606
Synonyms: GA_x6K02T2PBJ9-6173009-6173968, MOR17-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259098
Homologene: 110570
Nlrp4f
Name: NLR family, pyrin domain containing 4F
Synonyms: Nalp-kappa, C330026N02Rik, Nalp4f
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 97895
VEGA: 13
Homologene: 87252
Vmn2r86
Name: vomeronasal 2, receptor 86
Synonyms: EG625109
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 625109
Homologene: 129606
Tubgcp4
Name: tubulin, gamma complex associated protein 4
Synonyms: 4932441P04Rik, D2Ertd435e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 51885
Homologene: 8690
Adgrf2
Name: adhesion G protein-coupled receptor F2
Synonyms: PGR20, Gpr111
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 435529
Homologene: 45213
Zfp873
Name: zinc finger protein 873
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 408062
Homologene: 134319
Gm12814
Name: predicted gene 12814
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 630887
Bak1
Name: BCL2-antagonist/killer 1
Synonyms: Bak, N-Bak
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12018
HGNC: HGNC:949
Homologene: 917
Olfr5
Name: olfactory receptor 5
Synonyms: MOR103-8, GA_x6K02T2QGBW-3210997-3210059
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18349
Homologene: 72037
Olfr1145
Name: olfactory receptor 1145
Synonyms: GA_x6K02T2Q125-49311440-49312384, MOR264-19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258317
Homologene: 27123
Tmem53
Name: transmembrane protein 53
Synonyms: 1700012A05Rik, 1500001P22Rik, 1110038M16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 68777
Homologene: 41573
Arhgef9
Name: CDC42 guanine nucleotide exchange factor (GEF) 9
Synonyms: collybistin, 9630036L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 236915
Homologene: 9053
Rspo2
Name: R-spondin 2
Synonyms: 2610028F08Rik, ftls
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239405
VEGA: 15
Homologene: 18235
Gm5409
Name: predicted pseudogene 5409
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 386551
C030034I22Rik
Name: RIKEN cDNA C030034I22 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 77533
C030037F17Rik
Name: RIKEN cDNA C030037F17 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 77475
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 57,401,440 bp
  • T to C, chromosome 1 at 77,511,717 bp
  • T to A, chromosome 1 at 82,489,838 bp
  • A to G, chromosome 1 at 189,658,350 bp
  • T to C, chromosome 2 at 27,005,400 bp
  • C to A, chromosome 2 at 87,810,645 bp
  • T to C, chromosome 2 at 118,712,003 bp
  • T to A, chromosome 2 at 121,189,401 bp
  • T to C, chromosome 3 at 98,233,044 bp
  • T to A, chromosome 3 at 136,083,211 bp
  • T to C, chromosome 4 at 24,503,008 bp
  • G to A, chromosome 4 at 42,934,817 bp
  • G to T, chromosome 4 at 63,387,093 bp
  • T to A, chromosome 4 at 112,584,588 bp
  • T to C, chromosome 4 at 117,265,952 bp
  • G to A, chromosome 4 at 123,466,046 bp
  • G to T, chromosome 5 at 20,896,546 bp
  • A to G, chromosome 5 at 76,915,214 bp
  • T to C, chromosome 5 at 77,054,536 bp
  • T to C, chromosome 5 at 117,324,921 bp
  • T to C, chromosome 5 at 120,542,518 bp
  • A to G, chromosome 5 at 123,997,006 bp
  • A to G, chromosome 5 at 125,294,092 bp
  • C to T, chromosome 6 at 41,419,585 bp
  • A to G, chromosome 6 at 85,467,145 bp
  • T to C, chromosome 6 at 119,953,895 bp
  • G to T, chromosome 7 at 6,481,038 bp
  • A to G, chromosome 7 at 18,647,332 bp
  • G to T, chromosome 7 at 30,965,997 bp
  • G to T, chromosome 7 at 103,452,243 bp
  • C to T, chromosome 7 at 126,413,406 bp
  • T to C, chromosome 8 at 14,743,463 bp
  • T to C, chromosome 8 at 27,396,733 bp
  • G to A, chromosome 8 at 56,538,617 bp
  • G to A, chromosome 8 at 70,486,099 bp
  • T to A, chromosome 8 at 92,901,624 bp
  • T to C, chromosome 8 at 105,337,351 bp
  • G to A, chromosome 9 at 21,737,952 bp
  • A to T, chromosome 9 at 39,600,077 bp
  • A to G, chromosome 9 at 108,483,555 bp
  • A to G, chromosome 9 at 114,709,309 bp
  • A to G, chromosome 10 at 82,060,874 bp
  • A to G, chromosome 10 at 123,042,982 bp
  • T to C, chromosome 10 at 130,452,976 bp
  • C to A, chromosome 11 at 102,433,281 bp
  • T to C, chromosome 11 at 118,081,973 bp
  • G to A, chromosome 12 at 100,146,027 bp
  • A to T, chromosome 13 at 9,878,555 bp
  • G to T, chromosome 13 at 11,717,066 bp
  • T to G, chromosome 13 at 40,860,525 bp
  • C to T, chromosome 13 at 65,184,962 bp
  • T to G, chromosome 13 at 101,694,384 bp
  • T to C, chromosome 13 at 112,947,247 bp
  • T to A, chromosome 14 at 30,889,864 bp
  • T to C, chromosome 15 at 43,169,754 bp
  • T to C, chromosome 15 at 101,947,940 bp
  • G to A, chromosome 16 at 94,138,960 bp
  • C to A, chromosome 17 at 15,402,183 bp
  • C to A, chromosome 17 at 27,021,324 bp
  • C to A, chromosome 17 at 32,774,833 bp
  • T to A, chromosome 17 at 32,774,834 bp
  • T to C, chromosome 17 at 42,713,155 bp
  • T to C, chromosome 17 at 69,418,158 bp
  • T to C, chromosome 18 at 41,912,396 bp
  • C to T, chromosome 19 at 6,049,921 bp
  • G to A, chromosome 19 at 36,845,653 bp
  • T to G, chromosome X at 95,101,064 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4422 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
041695-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.