Strain Name:
C57BL/6J-MtgxR4576Btlr/Mmmh
Stock Number:
041799-MU
Citation ID:
RRID:MMRRC_041799-MU
Other Names:
R4576 (G1), C57BL/6J-MtgxR4576Btlr
Major Collection:

Gene Information

Fzd9
Name: frizzled class receptor 9
Synonyms: mfz9, frizzled 9, Fz9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14371
HGNC: HGNC:4047
Homologene: 2619
Ppp1r14c
Name: protein phosphatase 1, regulatory inhibitor subunit 14C
Synonyms: 6330514J04Rik, KEPI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 76142
VEGA: 10
Homologene: 12805
Enah
Name: ENAH actin regulator
Synonyms: Mena, Ndpp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13800
Homologene: 134005
Plxnd1
Name: plexin D1
Synonyms: b2b553Clo, b2b1863Clo, 6230425C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 67784
HGNC: HGNC:9107
Homologene: 22866
Zc3h4
Name: zinc finger CCCH-type containing 4
Synonyms: Bwq1, Kiaa1064-hp, LOC330474
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 330474
Homologene: 87150
Foxj3
Name: forkhead box J3
Synonyms: C330039G02Rik, Fhd6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230700
Homologene: 35243
Auts2
Name: autism susceptibility candidate 2
Synonyms: 2700063G02Rik, D830032G16Rik, A730011F23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 319974
Homologene: 22907
Kntc1
Name: kinetochore associated 1
Synonyms: jgl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 208628
Homologene: 32227
Trip11
Name: thyroid hormone receptor interactor 11
Synonyms: GMAP-210, 3110031G15Rik, 2610511G22Rik, 6030460N08Rik, TRIP230
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 109181
Homologene: 20897
Sec16a
Name: SEC16 homolog A, endoplasmic reticulum export factor
Synonyms: C230052J16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227648
Homologene: 10533
Prss16
Name: protease, serine 16 (thymus)
Synonyms: TSSP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 54373
HGNC: HGNC:9480
Homologene: 38106
Slitrk6
Name: SLIT and NTRK-like family, member 6
Synonyms: 4832410J21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239250
VEGA: 14
Homologene: 12986
Ift80
Name: intraflagellar transport 80
Synonyms: 4921524P20Rik, Wdr56
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 68259
Homologene: 12253
Ccser2
Name: coiled-coil serine rich 2
Synonyms: 1700012P13Rik, 2900054P12Rik, Gcap14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 72972
Homologene: 10367
Ecpas
Name: Ecm29 proteasome adaptor and scaffold
Synonyms: AI314180
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230249
Homologene: 6056
Thbs1
Name: thrombospondin 1
Synonyms: TSP-1, Thbs-1, TSP1, tbsp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 21825
Homologene: 31142
Dsp
Name: desmoplakin
Synonyms: DP, 5730453H04Rik, 2300002E22Rik, rul
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 109620
HGNC: HGNC:3052
Homologene: 37922
Mef2a
Name: myocyte enhancer factor 2A
Synonyms: A430079H05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17258
HGNC: HGNC:6993
Homologene: 4080
Cdh9
Name: cadherin 9
Synonyms: T1-cadherin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12565
HGNC: HGNC:1768
Homologene: 9450
Chst2
Name: carbohydrate sulfotransferase 2
Synonyms: C130041E03Rik, GST-2, Gn6st, N-acetylglucosamine-6-O-sulfotransferase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 54371
HGNC: HGNC:1970
Homologene: 3150
Klk12
Name: kallikrein related-peptidase 12
Synonyms: 2310008B01Rik, KLK-L5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 69511
HGNC: HGNC:6360
Homologene: 44690
Grhl3
Name: grainyhead like transcription factor 3
Synonyms: Get1, Som, ct
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230824
Homologene: 18864
Pum3
Name: pumilio RNA-binding family member 3
Synonyms: D19Bwg1357e, 1110069H02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 52874
VEGA: 19
Homologene: 5762
Ddx17
Name: DEAD box helicase 17
Synonyms: p72, LOC381024, DEAD (Asp-Glu-Ala-Asp) box polypeptide 17, 2610007K22Rik, A430025E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 67040
VEGA: 15
HGNC: HGNC:2740
Homologene: 101101
Srpr
Name: signal recognition particle receptor ('docking protein')
Synonyms: 1300011P19Rik, D11Mgi27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 67398
Homologene: 2364
Dapk1
Name: death associated protein kinase 1
Synonyms: DAP-Kinase, 2810425C21Rik, 2310039H24Rik, D13Ucla1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 69635
VEGA: 13
HGNC: HGNC:2674
Homologene: 3626
Heatr6
Name: HEAT repeat containing 6
Synonyms: 2700008B19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217026
Homologene: 11116
Ncapg
Name: non-SMC condensin I complex, subunit G
Synonyms: Hcapg, MFT.M05.13, 5730507H05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 54392
Homologene: 44071
Gin1
Name: gypsy retrotransposon integrase 1
Synonyms: Zh2c2, 4930429M06Rik, 4930429M06
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 252876
Homologene: 69238
Ddx11
Name: DEAD/H box helicase 11
Synonyms: KRG2, CHLR1, CHL1, essa15a, DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11, 4732462I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 320209
VEGA: 17
HGNC: HGNC:2736
Homologene: 68973
Gm7102
Name: predicted gene 7102
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 633057
Atp4a
Name: ATPase, H+/K+ exchanging, gastric, alpha polypeptide
Synonyms: H+K+-transporting alpha 1, H+/K+-ATPase alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11944
HGNC: HGNC:819
Homologene: 68081
Elfn1
Name: leucine rich repeat and fibronectin type III, extracellular 1
Synonyms: A930017N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243312
Homologene: 18465
Lrp1
Name: low density lipoprotein receptor-related protein 1
Synonyms: A2mr, b2b1554Clo, CD91
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16971
HGNC: HGNC:6692
Homologene: 1744
Hmcn1
Name: hemicentin 1
Synonyms: EG545370, LOC240793
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 545370
Homologene: 23741
Kcnu1
Name: potassium channel, subfamily U, member 1
Synonyms: Kcnma3, Slo3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 16532
Homologene: 7392
Ttc16
Name: tetratricopeptide repeat domain 16
Synonyms: 1200002K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 338348
Homologene: 17011
C7
Name: complement component 7
Synonyms: LOC383055
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 109828
VEGA: 15
HGNC: HGNC:1346
Homologene: 489
Exoc7
Name: exocyst complex component 7
Synonyms: 70kDa, Exo70, sec70
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 53413
Homologene: 41019
Zfp941
Name: zinc finger protein 941
Synonyms: BC066028
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 407812
Plcb3
Name: phospholipase C, beta 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18797
VEGA: 19
HGNC: HGNC:9056
Homologene: 47960
Unc79
Name: unc-79 homolog
Synonyms: 9030205A07Rik, Mlca3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217843
Homologene: 41397
Tmem175
Name: transmembrane protein 175
Synonyms: 3010001K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 72392
Homologene: 12461
Pxdn
Name: peroxidasin
Synonyms: VPO1, 2310075M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 69675
Homologene: 33907
Pde4dip
Name: phosphodiesterase 4D interacting protein (myomegalin)
Synonyms: D3Bwg1078e, 9430063L05Rik, 4732458A06Rik, D130016K21Rik, Usmg4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 83679
Homologene: 66961
Trim30b
Name: tripartite motif-containing 30B
Synonyms: Trim30-1, A530023O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244183
Adhfe1
Name: alcohol dehydrogenase, iron containing, 1
Synonyms: 6330565B14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 76187
Homologene: 5865
Ano9
Name: anoctamin 9
Synonyms: Tp53i5, 5430425C04Rik, Tmem16j, Trp53i5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 71345
Homologene: 67083
Kctd1
Name: potassium channel tetramerisation domain containing 1
Synonyms: 4933402K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 106931
VEGA: 18
Homologene: 65999
Slco6b1
Name: solute carrier organic anion transporter family, member 6b1
Synonyms: 1700022M03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 67854
Homologene: 12199
Atp8a1
Name: ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
Synonyms: Atp3a2, B230107D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11980
Homologene: 48402
Cntn5
Name: contactin 5
Synonyms: 6720426O10Rik, A830025P08Rik, LOC244683, NB-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244682
HGNC: HGNC:2175
Homologene: 28447
Svop
Name: SV2 related protein
Synonyms: 1110030H18Rik, msvop
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 68666
Homologene: 41283
Vmn2r16
Name: vomeronasal 2, receptor 16
Synonyms: EG384220
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 384220
Homologene: 104825
Chml
Name: choroideremia-like
Synonyms: E030003F13Rik, Rep2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12663
HGNC: HGNC:1941
Homologene: 31055
Traf3ip2
Name: TRAF3 interacting protein 2
Synonyms: Act1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 103213
HGNC: HGNC:1343
Homologene: 15885
Pnpla2
Name: patatin-like phospholipase domain containing 2
Synonyms: desnutrin, 0610039C21Rik, 1110001C14Rik, Atgl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 66853
Homologene: 10687
Fam166a
Name: family with sequence similarity 166, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68222
Homologene: 12247
Hkdc1
Name: hexokinase domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216019
Homologene: 128937
Samhd1
Name: SAM domain and HD domain, 1
Synonyms: E330031J07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 56045
Homologene: 9160
Vmn1r74
Name: vomeronasal 1 receptor 74
Synonyms: V1rg5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 171240
Homologene: 110796
H6pd
Name: hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
Synonyms: G6pd1, Gpd1, Gpd-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100198
HGNC: HGNC:4795
Homologene: 48275
Edil3
Name: EGF-like repeats and discoidin I-like domains 3
Synonyms: developmental endothelial locus-1, Del-1, Del1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 13612
HGNC: HGNC:3173
Homologene: 21166
Pknox2
Name: Pbx/knotted 1 homeobox 2
Synonyms: Prep2, D230005H23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 208076
Homologene: 32527
Tmem161a
Name: transmembrane protein 161A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234371
Homologene: 9853
Spef1l
Name: sperm flagellar 1 like
Synonyms: LOC381933, 6430531B16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381933
Homologene: 134514
Rasgrf2
Name: RAS protein-specific guanine nucleotide-releasing factor 2
Synonyms: 6330417G04Rik, Grf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 19418
HGNC: HGNC:9876
Homologene: 2169
Tacc3
Name: transforming, acidic coiled-coil containing protein 3
Synonyms: Aint, Arnt interacting protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 21335
Homologene: 81618
Maml3
Name: mastermind like transcriptional coactivator 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 433586
Homologene: 41284
Mlc1
Name: megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)
Synonyms: WKL1, Kiaa0027-hp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 170790
Homologene: 15775
Lpxn
Name: leupaxin
Synonyms: A530083L21Rik, 4933402K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 107321
VEGA: 19
Homologene: 3536
Cln6
Name: ceroid-lipofuscinosis, neuronal 6
Synonyms: 1810065L06Rik, D9Bwg1455e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 76524
HGNC: HGNC:2077
Homologene: 9898
Fgfbp1
Name: fibroblast growth factor binding protein 1
Synonyms: FGF-BP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14181
Homologene: 3766
Tssk5
Name: testis-specific serine kinase 5
Synonyms: 1700091F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 73542
VEGA: 15
Homologene: 18832
Zfp970
Name: zinc finger protein 970
Synonyms: Gm14420
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 628308
Homologene: 134324
Cirbp
Name: cold inducible RNA binding protein
Synonyms: Cirp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 12696
HGNC: HGNC:1982
Homologene: 980
Tango2
Name: transport and golgi organization 2
Synonyms: T10, D16H22S680E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 27883
Homologene: 44029
Pcdhga9
Name: protocadherin gamma subfamily A, 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93717
HGNC: HGNC:8707
Homologene: 56827
Heatr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Gm10804
Name: predicted gene 10804
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 100038525
Llph-ps2
Name: LLP homolog, pseudogene 2
Synonyms: ENSMUSG00000058791, Gm14535
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 100043002
Homologene: 81946
Spata31d1b
Name: spermatogenesis associated 31 subfamily D, member 1B
Synonyms: Fam75d1b, Gm4934
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238662
VEGA: 13
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 9,553,754 bp
  • T to A, chromosome 1 at 96,988,697 bp
  • A to G, chromosome 1 at 97,792,339 bp
  • G to T, chromosome 1 at 150,734,487 bp
  • G to T, chromosome 1 at 175,686,940 bp
  • G to A, chromosome 1 at 181,919,563 bp
  • T to C, chromosome 2 at 25,220,288 bp
  • A to T, chromosome 2 at 26,431,119 bp
  • A to T, chromosome 2 at 32,770,059 bp
  • C to T, chromosome 2 at 93,468,669 bp
  • G to A, chromosome 2 at 118,119,416 bp
  • A to T, chromosome 2 at 157,101,750 bp
  • A to T, chromosome 2 at 177,475,680 bp
  • G to A, chromosome 3 at 51,856,506 bp
  • A to G, chromosome 3 at 68,950,530 bp
  • C to A, chromosome 3 at 97,754,249 bp
  • A to T, chromosome 4 at 58,834,708 bp
  • A to G, chromosome 4 at 119,621,663 bp
  • G to T, chromosome 4 at 135,561,251 bp
  • A to T, chromosome 4 at 149,994,476 bp
  • T to A, chromosome 5 at 33,661,497 bp
  • C to T, chromosome 5 at 43,979,464 bp
  • A to G, chromosome 5 at 45,681,789 bp
  • T to C, chromosome 5 at 67,815,815 bp
  • A to G, chromosome 5 at 108,644,602 bp
  • A to T, chromosome 5 at 109,363,799 bp
  • C to T, chromosome 5 at 114,065,682 bp
  • T to G, chromosome 5 at 123,765,955 bp
  • C to T, chromosome 5 at 132,258,934 bp
  • A to G, chromosome 5 at 135,250,312 bp
  • C to A, chromosome 5 at 139,185,639 bp
  • T to C, chromosome 5 at 139,972,053 bp
  • G to A, chromosome 6 at 115,968,044 bp
  • A to G, chromosome 7 at 11,846,769 bp
  • G to A, chromosome 7 at 16,434,654 bp
  • A to G, chromosome 7 at 30,717,722 bp
  • A to G, chromosome 7 at 43,773,243 bp
  • T to C, chromosome 7 at 67,240,439 bp
  • T to C, chromosome 7 at 104,357,331 bp
  • A to G, chromosome 7 at 139,978,130 bp
  • T to A, chromosome 7 at 140,811,590 bp
  • T to C, chromosome 7 at 141,104,138 bp
  • T to C, chromosome 7 at 141,457,344 bp
  • A to T, chromosome 8 at 25,890,020 bp
  • T to C, chromosome 8 at 70,182,063 bp
  • A to G, chromosome 9 at 9,673,292 bp
  • T to C, chromosome 9 at 35,214,608 bp
  • A to G, chromosome 9 at 36,923,548 bp
  • G to T, chromosome 9 at 62,838,949 bp
  • T to C, chromosome 9 at 95,405,171 bp
  • G to T, chromosome 10 at 3,366,912 bp
  • A to G, chromosome 10 at 39,634,654 bp
  • T to C, chromosome 10 at 62,385,843 bp
  • A to G, chromosome 10 at 80,170,241 bp
  • C to T, chromosome 10 at 93,043,228 bp
  • ACAGGCGC to AC, chromosome 10 at 127,540,188 bp
  • T to A, chromosome 11 at 83,765,000 bp
  • T to C, chromosome 11 at 116,289,183 bp
  • A to T, chromosome 12 at 30,011,923 bp
  • G to A, chromosome 12 at 101,886,240 bp
  • T to C, chromosome 12 at 103,001,803 bp
  • C to T, chromosome 13 at 22,009,552 bp
  • C to T, chromosome 13 at 38,181,160 bp
  • C to A, chromosome 13 at 59,716,861 bp
  • A to T, chromosome 13 at 60,721,822 bp
  • T to C, chromosome 13 at 89,319,731 bp
  • T to C, chromosome 13 at 91,896,410 bp
  • A to G, chromosome 14 at 36,898,242 bp
  • C to A, chromosome 14 at 110,750,170 bp
  • A to G, chromosome 15 at 5,002,756 bp
  • T to C, chromosome 15 at 16,832,239 bp
  • C to T, chromosome 15 at 76,372,468 bp
  • A to T, chromosome 15 at 79,541,146 bp
  • G to A, chromosome 15 at 88,974,537 bp
  • A to T, chromosome 16 at 18,301,528 bp
  • A to G, chromosome 17 at 66,150,726 bp
  • A to G, chromosome 18 at 15,007,700 bp
  • A to C, chromosome 18 at 37,737,828 bp
  • C to T, chromosome 19 at 6,959,047 bp
  • T to C, chromosome 19 at 12,833,290 bp
  • G to A, chromosome 19 at 27,415,908 bp
  • C to T, chromosome 19 at 61,175,926 bp
  • A to G, chromosome X at 13,218,451 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4576 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
041799-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.