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Strain Name:
C57BL/6J-MtgxR4579Btlr/Mmmh
Stock Number:
041801-MU
Citation ID:
RRID:MMRRC_041801-MU
Other Names:
R4579 (G1), C57BL/6J-MtgxR4579Btlr
Major Collection:

Strain Information

Pdpk1
Name: 3-phosphoinositide dependent protein kinase 1
Synonyms: Pkb kinase, Pdk1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18607
Homologene: 37643
Bmp6
Name: bone morphogenetic protein 6
Synonyms: Vgr1, D13Wsu115e
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 12161
VEGA: 13
HGNC: HGNC:1073
Homologene: 1300
Ank2
Name: ankyrin 2, brain
Synonyms: ankyrin B, Ank-2, Ankyrin-2, Ankyrin-B, Gm4392
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 109676
HGNC: HGNC:493
Galr2
Name: galanin receptor 2
Synonyms: mGalR, GalR2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14428
HGNC: HGNC:4133
Homologene: 2863
Med1
Name: mediator complex subunit 1
Synonyms: TRAP 220, TRAP220, CRSP210, DRIP205, Pparbp, l11Jus15, PBP
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19014
HGNC: HGNC:9234
Homologene: 21002
Pds5b
Name: PDS5 cohesin associated factor B
Synonyms: AS3, Aprin
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100710
Homologene: 41001
Col6a1
Name: collagen, type VI, alpha 1
Synonyms: Col6a-1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 12833
HGNC: HGNC:2211
Homologene: 1391
Nf1
Name: neurofibromin 1
Synonyms: neurofibromin, Nf-1, Dsk9, Mhdadsk9
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18015
HGNC: HGNC:7765
Homologene: 226
Eprs1
Name: glutamyl-prolyl-tRNA synthetase 1
Synonyms: 2410081F06Rik, Qprs, 3010002K18Rik, Eprs
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 107508
HGNC: HGNC:3418
Homologene: 5870
Atad5
Name: ATPase family, AAA domain containing 5
Synonyms: LOC237877, C130052G03Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237877
Homologene: 32611
Fancl
Name: Fanconi anemia, complementation group L
Synonyms: 2010322C19Rik, gcd, Pog, Phf9, B230118H11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 67030
Homologene: 9987
Pop1
Name: processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)
Synonyms: 4932434G09Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 67724
Homologene: 41000
Hectd1
Name: HECT domain E3 ubiquitin protein ligase 1
Synonyms: A630086P08Rik, opm, b2b327Clo
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 207304
VEGA: 12
Homologene: 9115
Mical3
Name: microtubule associated monooxygenase, calponin and LIM domain containing 3
Synonyms: MICAL-3, C130040D16Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 194401
Homologene: 85288
Ccnf
Name: cyclin F
Synonyms: CycF, Fbxo1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12449
VEGA: 17
HGNC: HGNC:1591
Homologene: 1335
Gnpat
Name: glyceronephosphate O-acyltransferase
Synonyms: D1Ertd819e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14712
HGNC: HGNC:4416
Homologene: 40716
Pex1
Name: peroxisomal biogenesis factor 1
Synonyms: ZWS1, 5430414H02Rik, E330005K07Rik, peroxisome biogenesis factor 1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71382
HGNC: HGNC:8850
Homologene: 27006
Fam120c
Name: family with sequence similarity 120, member C
Synonyms: D930001I21Rik, orf34
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 207375
Homologene: 9876
Atp5f1a
Name: ATP synthase F1 subunit alpha
Synonyms: Atpm, D18Ertd206e, Mom2, Atp5a1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 11946
HGNC: HGNC:823
Homologene: 2985
Lamc1
Name: laminin, gamma 1
Synonyms: Lamb2, laminin B2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226519
HGNC: HGNC:6492
Homologene: 1724
Lmo7
Name: LIM domain only 7
Synonyms: LOC380928, FBXO20
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 380928
HGNC: HGNC:6646
Homologene: 83924
Cux2
Name: cut-like homeobox 2
Synonyms: Cux-2, Cux2, ENSMUSG00000072641, Cutl2, 1700051K22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13048
Homologene: 22426
Atp13a5
Name: ATPase type 13A5
Synonyms: C630015F21Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 268878
Homologene: 77451
Man2a1
Name: mannosidase 2, alpha 1
Synonyms: Mana-2, Mana2, Map-2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17158
HGNC: HGNC:6824
Homologene: 1777
Bub1b
Name: BUB1B, mitotic checkpoint serine/threonine kinase
Synonyms: BUBR1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12236
HGNC: HGNC:1149
Homologene: 933
Twf2
Name: twinfilin actin binding protein 2
Synonyms: A6-related, Twf2, Twinfilin-2, Ptk9l
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 23999
HGNC: HGNC:9621
Homologene: 5272
Zfp524
Name: zinc finger protein 524
Synonyms: 0610012F07Rik, 2300009P13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 66056
Homologene: 11912
Cul2
Name: cullin 2
Synonyms: 1300003D18Rik, 4932411N15Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 71745
HGNC: HGNC:2552
Homologene: 2662
Prkaa1
Name: protein kinase, AMP-activated, alpha 1 catalytic subunit
Synonyms: C130083N04Rik, AMPKalpha1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 105787
VEGA: 15
HGNC: HGNC:9376
Homologene: 49590
Dpy19l4
Name: dpy-19 like 4
Synonyms: LOC381510, Narg3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 381510
Homologene: 18773
Slc38a6
Name: solute carrier family 38, member 6
Synonyms: EG625098
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 625098
Homologene: 27550
Kbtbd2
Name: kelch repeat and BTB (POZ) domain containing 2
Synonyms: Bklhd1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 210973
Homologene: 17122
Fance
Name: Fanconi anemia, complementation group E
Synonyms: 2810451D06Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 72775
HGNC: HGNC:3586
Homologene: 11066
Gnao1
Name: guanine nucleotide binding protein, alpha O
Synonyms: Go alpha, alphaO, Galphao
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14681
HGNC: HGNC:4389
Homologene: 39203
Myo7a
Name: myosin VIIA
Synonyms: Myo7, USH1B, nmf371, polka, Hdb
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17921
HGNC: HGNC:7606
Homologene: 219
Tek
Name: TEK receptor tyrosine kinase
Synonyms: Hyk, Tie2, Cd202b, tie-2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21687
Homologene: 397
Ndst3
Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
Synonyms: 4930511P15Rik, 4921531K01Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 83398
HGNC: HGNC:7682
Homologene: 3513
Ksr2
Name: kinase suppressor of ras 2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 333050
Homologene: 45469
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Dchs1
Name: dachsous cadherin related 1
Synonyms: C130033F22Rik, 3110041P15Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233651
Homologene: 2771
Dnah3
Name: dynein, axonemal, heavy chain 3
Synonyms: Dnahc3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 381917
HGNC: HGNC:2949
Homologene: 19674
Dner
Name: delta/notch-like EGF repeat containing
Synonyms: BET, A930026D19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227325
Homologene: 26722
Fbxo30
Name: F-box protein 30
Synonyms: 1700026A16Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71865
Homologene: 12959
Slc4a5
Name: solute carrier family 4, sodium bicarbonate cotransporter, member 5
Synonyms: C330016K18Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232156
Homologene: 31125
Adamts16
Name: ADAM metallopeptidase with thrombospondin type 1 motif 16
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 271127
Homologene: 15146
Ermp1
Name: endoplasmic reticulum metallopeptidase 1
Synonyms: D19Ertd410e, D19Wsu12e, b2b2633Clo
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226090
Homologene: 121891
F830045P16Rik
Name: RIKEN cDNA F830045P16 gene
Synonyms: Sirpb3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228592
Homologene: 136180
Itgal
Name: integrin alpha L
Synonyms: LFA-1, Cd11a, Ly-21, Ly-15
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16408
HGNC: HGNC:6148
Homologene: 1666
Pitrm1
Name: pitrilysin metallepetidase 1
Synonyms: 2310012C15Rik, MP-1, Ntup1, PreP
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 69617
VEGA: 13
Homologene: 5742
Bdh1
Name: 3-hydroxybutyrate dehydrogenase, type 1
Synonyms: 2310032J20Rik, Bdh
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 71911
HGNC: HGNC:1027
Homologene: 20860
L3mbtl4
Name: L3MBTL4 histone methyl-lysine binding protein
Synonyms: D930040M24Rik, A730037L19Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 320858
Homologene: 114383
Or4c111
Name: olfactory receptor family 4 subfamily C member 111
Synonyms: GA_x6K02T2Q125-50494588-50493653, MOR233-9, Olfr1216
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258895
Homologene: 74241
Or8b12i
Name: olfactory receptor family 8 subfamily B member 12I
Synonyms: GA_x6K02T2PVTD-13912679-13911744, MOR141-1, Olfr870
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 57251
Homologene: 138319
Cyp3a57
Name: cytochrome P450, family 3, subfamily a, polypeptide 57
Synonyms: EG622127
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 622127
Homologene: 135775
Pcdhb2
Name: protocadherin beta 2
Synonyms: PcdhbB
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93873
HGNC: HGNC:8687
Homologene: 69266
Miip
Name: migration and invasion inhibitory protein
Synonyms: D4Wsu114e
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 28010
Homologene: 15879
Zfp788
Name: zinc finger protein 788
Synonyms: 2810426N06Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67607
Homologene: 137363
Zfp1004
Name: zinc finger protein 1004
Synonyms: Gm14139
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 100271882
Homologene: 134546
Dzip1l
Name: DAZ interacting protein 1-like
Synonyms: 2610524A10Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 72507
Homologene: 12466
Slc5a9
Name: solute carrier family 5 (sodium/glucose cotransporter), member 9
Synonyms: SGLT4
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230612
Homologene: 17081
Or8k28
Name: olfactory receptor family 8 subfamily K member 28
Synonyms: GA_x6K02T2Q125-47925557-47924616, MOR188-8, MOR256-52P, Olfr1066
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 257880
Homologene: 79468
Vmn1r177
Name: vomeronasal 1 receptor 177
Synonyms: V1rd12
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 384572
Homologene: 122945
Or2f2
Name: olfactory receptor family 2 subfamily F member 2
Synonyms: GA_x6K02T2P3E9-4769843-4768890, MOR257-5P, Olfr452
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 258207
HGNC: HGNC:8247
Homologene: 128141
Ajm1
Name: apical junction component 1
Synonyms: LOC381353, Gm996
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 381353
Homologene: 19943
Togaram1
Name: TOG array regulator of axonemal microtubules 1
Synonyms: A430041B07Rik, Fam179b
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 328108
VEGA: 12
Homologene: 15025
Ldha
Name: lactate dehydrogenase A
Synonyms: lactate dehydrogenase-A, LDH-A, Ldh-1, l7R2, Ldh1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16828
HGNC: HGNC:6535
Homologene: 56495
Cyp2c69
Name: cytochrome P450, family 2, subfamily c, polypeptide 69
Synonyms: AI098658
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 100043108
VEGA: 19
Homologene: 74936
Ugt1a10
Name: UDP glycosyltransferase 1 family, polypeptide A10
Synonyms: A13
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 394430
Homologene: 133281
Or8s10
Name: olfactory receptor family 8 subfamily S member 1
Synonyms: GA_x6K02T2NBG7-5293798-5292872, MOR160-2, Olfr282
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 258449
Homologene: 133621
Trim56
Name: tripartite motif-containing 56
Synonyms: LOC384309, RNF109, A130009K11Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 384309
Homologene: 12812
Or2n1b
Name: olfactory receptor family 2 subfamily N member 1B
Synonyms: MOR256-6, GA_x6K02T2PSCP-2597192-2598130, Olfr133
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 258828
Homologene: 110603
Opalin
Name: oligodendrocytic myelin paranodal and inner loop protein
Synonyms: Tmp10, Tmem10
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226115
VEGA: 19
Homologene: 13237
Vmn1r44
Name: vomeronasal 1 receptor 44
Synonyms: V1rb4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113854
Homologene: 113975
Hsd3b6
Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6
Synonyms: 3beta-HSD VI
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 15497
Homologene: 133013
Acox3
Name: acyl-Coenzyme A oxidase 3, pristanoyl
Synonyms: pristanoyl-CoA oxidase, PCOX, EST-s59
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 80911
HGNC: HGNC:121
Homologene: 37792
Pdap1
Name: PDGFA associated protein 1
Synonyms: HASPP28, PAP1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231887
Homologene: 8927
Tbcb
Name: tubulin folding cofactor B
Synonyms: 2410007D12Rik, Ckap1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 66411
HGNC: HGNC:1989
Homologene: 981
Spata3
Name: spermatogenesis associated 3
Synonyms: 4930424D10Rik, 1700011N12Rik, TSARG1, 1700029H01Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 70060
Homologene: 12517
Hint3
Name: histidine triad nucleotide binding protein 3
Synonyms: 0610010I17Rik, HINT4
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 66847
Homologene: 12046
Tssk3
Name: testis-specific serine kinase 3
Synonyms: Tssk-3, 4930594I21Rik, Stk22d, Stk22c, 1700014N07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 58864
Homologene: 62163
Gm4845
Name: predicted gene 4845
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226472
A930004D18Rik
Name: RIKEN cDNA A930004D18 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 77940
Gm17782
Name: predicted gene, 17782
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 84,383,816 bp
  • T to A, chromosome 1 at 86,026,453 bp
  • T to C, chromosome 1 at 88,056,116 bp
  • T to G, chromosome 1 at 141,257,127 bp
  • T to C, chromosome 1 at 153,247,269 bp
  • A to G, chromosome 1 at 185,401,607 bp
  • A to G, chromosome 2 at 18,027,037 bp
  • T to A, chromosome 2 at 25,579,649 bp
  • G to A, chromosome 2 at 76,896,803 bp
  • T to C, chromosome 2 at 86,455,515 bp
  • T to C, chromosome 2 at 89,013,144 bp
  • C to A, chromosome 2 at 118,623,176 bp
  • A to G, chromosome 2 at 129,463,503 bp
  • T to A, chromosome 2 at 150,192,223 bp
  • T to C, chromosome 3 at 19,957,435 bp
  • A to G, chromosome 3 at 98,806,225 bp
  • A to T, chromosome 3 at 123,546,825 bp
  • A to T, chromosome 3 at 126,958,963 bp
  • A to G, chromosome 4 at 11,317,131 bp
  • T to A, chromosome 4 at 94,863,666 bp
  • T to A, chromosome 4 at 111,893,187 bp
  • A to T, chromosome 4 at 129,489,317 bp
  • G to A, chromosome 4 at 147,861,061 bp
  • C to A, chromosome 5 at 3,618,880 bp
  • A to G, chromosome 5 at 35,604,643 bp
  • A to T, chromosome 5 at 114,256,825 bp
  • A to T, chromosome 5 at 117,756,270 bp
  • A to T, chromosome 5 at 121,860,653 bp
  • A to C, chromosome 5 at 137,114,064 bp
  • A to G, chromosome 5 at 145,136,881 bp
  • A to G, chromosome 5 at 145,374,264 bp
  • A to G, chromosome 5 at 150,746,732 bp
  • A to T, chromosome 6 at 42,790,524 bp
  • A to T, chromosome 6 at 56,778,908 bp
  • T to C, chromosome 6 at 83,290,834 bp
  • T to A, chromosome 6 at 89,893,933 bp
  • A to T, chromosome 6 at 120,958,699 bp
  • G to A, chromosome 7 at 5,018,348 bp
  • A to T, chromosome 7 at 23,866,347 bp
  • T to A, chromosome 7 at 30,231,594 bp
  • T to G, chromosome 7 at 41,647,594 bp
  • C to A, chromosome 7 at 46,850,249 bp
  • C to A, chromosome 7 at 98,073,193 bp
  • T to G, chromosome 7 at 105,754,765 bp
  • A to G, chromosome 7 at 105,758,973 bp
  • T to C, chromosome 7 at 120,009,331 bp
  • A to G, chromosome 7 at 127,305,294 bp
  • A to T, chromosome 8 at 93,966,904 bp
  • T to A, chromosome 8 at 124,878,502 bp
  • G to T, chromosome 9 at 20,171,114 bp
  • A to T, chromosome 9 at 99,647,214 bp
  • G to A, chromosome 9 at 106,212,826 bp
  • T to A, chromosome 10 at 11,289,549 bp
  • T to C, chromosome 10 at 30,610,432 bp
  • C to T, chromosome 10 at 76,711,357 bp
  • G to T, chromosome 11 at 26,468,423 bp
  • T to A, chromosome 11 at 79,468,757 bp
  • T to C, chromosome 11 at 80,095,191 bp
  • T to G, chromosome 11 at 98,158,422 bp
  • A to T, chromosome 11 at 116,281,499 bp
  • A to G, chromosome 12 at 51,744,573 bp
  • G to T, chromosome 12 at 64,967,907 bp
  • G to T, chromosome 12 at 73,288,524 bp
  • G to A, chromosome 13 at 6,558,225 bp
  • A to T, chromosome 13 at 38,469,725 bp
  • A to G, chromosome 13 at 70,779,624 bp
  • T to C, chromosome 14 at 101,900,500 bp
  • A to G, chromosome 15 at 5,160,601 bp
  • G to A, chromosome 15 at 34,515,824 bp
  • A to T, chromosome 15 at 98,437,679 bp
  • T to C, chromosome 16 at 29,248,338 bp
  • A to T, chromosome 16 at 31,436,136 bp
  • T to C, chromosome 17 at 24,093,560 bp
  • T to A, chromosome 17 at 24,231,329 bp
  • C to T, chromosome 17 at 25,959,837 bp
  • T to A, chromosome 17 at 28,317,151 bp
  • C to T, chromosome 17 at 36,161,757 bp
  • G to C, chromosome 17 at 38,149,405 bp
  • A to G, chromosome 17 at 64,714,675 bp
  • A to T, chromosome 17 at 68,764,640 bp
  • T to C, chromosome 18 at 3,430,957 bp
  • T to A, chromosome 18 at 37,296,115 bp
  • T to C, chromosome 18 at 77,780,102 bp
  • A to T, chromosome 19 at 29,616,651 bp
  • T to A, chromosome 19 at 39,881,186 bp
  • A to G, chromosome 19 at 41,067,757 bp
  • G to T, chromosome X at 151,436,183 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4579 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
041801-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.