Strain Name:
C57BL/6J-MtgxR4581Btlr/Mmmh
Stock Number:
041802-MU
Citation ID:
RRID:MMRRC_041802-MU
Other Names:
R4581 (G1), C57BL/6J-MtgxR4581Btlr
Major Collection:

Gene Information

Tgfb1
Name: transforming growth factor, beta 1
Synonyms: TGF-beta 1, Tgfb-1, Tgfb, TGFbeta1, TGF-beta1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 21803
Homologene: 540
Prdm16
Name: PR domain containing 16
Synonyms: Mel1, 5730557K01Rik, line 27, csp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 70673
Homologene: 11139
Tal1
Name: T cell acute lymphocytic leukemia 1
Synonyms: SCL/tal-1, Scl, bHLHa17, Hpt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 21349
Homologene: 2400
Kdm4c
Name: lysine (K)-specific demethylase 4C
Synonyms: 2410141F18Rik, Jmjd2c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 76804
Homologene: 41004
Rarg
Name: retinoic acid receptor, gamma
Synonyms: RARgamma2, RAR gamma 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 19411
HGNC: HGNC:9866
Homologene: 20263
Vps35l
Name: VPS35 endosomal protein sorting factor like
Synonyms: 9030624J02Rik, Vsp35l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 71517
Homologene: 10659
Ckap5
Name: cytoskeleton associated protein 5
Synonyms: 3110043H24Rik, 4930432B04Rik, D730027C18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 75786
Homologene: 8844
Ankrd17
Name: ankyrin repeat domain 17
Synonyms: 4933425K22Rik, Gtar, A130069E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 81702
Homologene: 82403
Znfx1
Name: zinc finger, NFX1-type containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 98999
Homologene: 10877
Ltn1
Name: listerin E3 ubiquitin protein ligase 1
Synonyms: 4930528H02Rik, Zfp294, Listerin, Rnf160
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 78913
VEGA: 16
Homologene: 32272
Ascc3
Name: activating signal cointegrator 1 complex subunit 3
Synonyms: ASC1p200, B630009I04Rik, Helic1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 77987
VEGA: 10
Homologene: 4973
Fbxl20
Name: F-box and leucine-rich repeat protein 20
Synonyms: C86145, Fbl2, 2610511F20Rik, 4632423N09Rik, Scr, Scrapper
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 72194
Homologene: 68784
Cog3
Name: component of oligomeric golgi complex 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 338337
VEGA: 14
Homologene: 5854
Urb1
Name: URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
Synonyms: 5730405K23Rik, 4921511H13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 207932
Homologene: 45941
Cep68
Name: centrosomal protein 68
Synonyms: 6030463E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216543
Homologene: 65235
Epha8
Name: Eph receptor A8
Synonyms: EphA8, Hek3, Eek
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13842
HGNC: HGNC:3391
Homologene: 22436
Mafa
Name: v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
Synonyms: RIPE3b1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 378435
VEGA: 15
Homologene: 65867
Src
Name: Rous sarcoma oncogene
Synonyms: pp60c-src
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20779
Homologene: 21120
Cenpe
Name: centromere protein E
Synonyms: N-7 kinesin, CENP-E, 312kDa, Kif10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229841
HGNC: HGNC:1856
Homologene: 20429
Dnaja1
Name: DnaJ heat shock protein family (Hsp40) member A1
Synonyms: Hsj2, Nedd7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 15502
HGNC: HGNC:5229
Homologene: 55588
Ttc7b
Name: tetratricopeptide repeat domain 7B
Synonyms: Ttc7l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 104718
VEGA: 12
Homologene: 14675
Camk1d
Name: calcium/calmodulin-dependent protein kinase ID
Synonyms: CKLiK, E030025C11Rik, A630059D12Rik, CaMKIdelta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227541
Homologene: 121858
Zfp574
Name: zinc finger protein 574
Synonyms: A630056B21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232976
Homologene: 11238
Taf6l
Name: TATA-box binding protein associated factor 6 like
Synonyms: PAF65A, C530024J06Rik, 2810417N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225895
Homologene: 4728
Spryd3
Name: SPRY domain containing 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223918
Homologene: 13138
Srcap
Name: Snf2-related CREBBP activator protein
Synonyms: F630004O05Rik, B930091H02Rik, D030022P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100043597
Homologene: 38213
Adgrd1
Name: adhesion G protein-coupled receptor D1
Synonyms: E230012M21Rik, Gpr133
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243277
Homologene: 34616
Pla2g4e
Name: phospholipase A2, group IVE
Synonyms: 2310026J01Rik, Pla2epsilon
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329502
Homologene: 65339
Plcd4
Name: phospholipase C, delta 4
Synonyms: 4921507K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18802
HGNC: HGNC:9062
Homologene: 88782
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Acz, Pico
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 26875
Homologene: 69111
Cox6a2
Name: cytochrome c oxidase subunit 6A2
Synonyms: COXVIaH, VIaH, subunit VIaH (heart-type)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12862
HGNC: HGNC:2279
Homologene: 38020
Trappc11
Name: trafficking protein particle complex 11
Synonyms: D030016E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 320714
Homologene: 11076
Fer1l6
Name: fer-1-like 6 (C. elegans)
Synonyms: EG631797
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 631797
Homologene: 53396
Cplane1
Name: ciliogenesis and planar polarity effector 1
Synonyms: b2b012Clo, Jbts17, Hug, 2410089E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 73692
Homologene: 11315
Stc2
Name: stanniocalcin 2
Synonyms: mustc2, Stc2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20856
Homologene: 2753
Dlgap2
Name: DLG associated protein 2
Synonyms: SAP90/PSD-95-associated protein 2, PSD-95/SAP90-binding protein 2, 6430596N04Rik, DAP2, Sapap2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244310
HGNC: HGNC:2906
Homologene: 3484
Cacna1s
Name: calcium channel, voltage-dependent, L type, alpha 1S subunit
Synonyms: Cchl1a3, fmd, mdg, sj, muscle dysgenesis, Cav1.1, DHPR alpha1s
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12292
HGNC: HGNC:1397
Homologene: 37257
Ankrd7
Name: ankyrin repeat domain 7
Synonyms: 4930532L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 75196
Homologene: 35506
Fbxw7
Name: F-box and WD-40 domain protein 7
Synonyms: SEL-10, AGO, Fbxo30, Fbxw6, 1110001A17Rik, Cdc4, Fbw7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 50754
Homologene: 117451
Myom2
Name: myomesin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 17930
HGNC: HGNC:7614
Homologene: 2953
Glis3
Name: GLIS family zinc finger 3
Synonyms: E330013K21Rik, 4833409N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226075
Homologene: 34989
Actc1
Name: actin, alpha, cardiac muscle 1
Synonyms: Actc-1, alphac-actin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11464
HGNC: HGNC:143
Homologene: 68446
4933427I04Rik
Name: Riken cDNA 4933427I04 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
VEGA: 4
Ddx60
Name: DExD/H box helicase 60
Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234311
Homologene: 23031
Top2b
Name: topoisomerase (DNA) II beta
Synonyms: Top-2, D230016L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 21974
Homologene: 134711
Arhgef4
Name: Rho guanine nucleotide exchange factor (GEF) 4
Synonyms: 9330140K16Rik, Asef, C230030N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226970
HGNC: HGNC:684
Homologene: 49414
Zfp93
Name: zinc finger protein 93
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22755
Homologene: 117959
Rfx4
Name: regulatory factor X, 4 (influences HLA class II expression)
Synonyms: 4933412G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71137
HGNC: HGNC:9985
Homologene: 31119
Csmd2
Name: CUB and Sushi multiple domains 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329942
Homologene: 89034
Fanca
Name: Fanconi anemia, complementation group A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14087
HGNC: HGNC:3582
Homologene: 108
Osmr
Name: oncostatin M receptor
Synonyms: OSMRB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 18414
HGNC: HGNC:8507
Homologene: 2972
Gm7535
Name: predicted gene 7535
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 665187
VEGA: 17
3425401B19Rik
Name: RIKEN cDNA 3425401B19 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 100504518
VEGA: 14
Homologene: 54908
Itih4
Name: inter alpha-trypsin inhibitor, heavy chain 4
Synonyms: Itih-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 16427
HGNC: HGNC:6169
Homologene: 1670
Sec14l4
Name: SEC14-like lipid binding 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 103655
Homologene: 68807
Cdh18
Name: cadherin 18
Synonyms: B230220E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 320865
HGNC: HGNC:1757
Homologene: 55858
Tmem8b
Name: transmembrane protein 8B
Synonyms: 4930500O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242409
Homologene: 72894
Vmn2r8
Name: vomeronasal 2, receptor 8
Synonyms: EG627479
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 627479
Homologene: 129606
Krt83
Name: keratin 83
Synonyms: 5430421N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 100126226
HGNC: HGNC:6460
Homologene: 68248
Six1
Name: sine oculis-related homeobox 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20471
Homologene: 4360
Olfr1082
Name: olfactory receptor 1082
Synonyms: GA_x6K02T2Q125-48079993-48079157, MOR192-4_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 404473
Homologene: 104285
Skint4
Name: selection and upkeep of intraepithelial T cells 4
Synonyms: 9530098N22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 320640
Abca7
Name: ATP-binding cassette, sub-family A (ABC1), member 7
Synonyms: Abc51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 27403
HGNC: HGNC:37
Homologene: 22783
Efhb
Name: EF hand domain family, member B
Synonyms: 4921525D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 211482
VEGA: 17
Homologene: 16982
Nyap1
Name: neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
Synonyms: Nyap1, 6430598A04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243300
Homologene: 18320
Slc25a23
Name: solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
Synonyms: 2310067G05Rik, SCaMC-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 66972
Homologene: 11467
Yipf4
Name: Yip1 domain family, member 4
Synonyms: 2310034L04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 67864
VEGA: 17
Homologene: 32658
Tfec
Name: transcription factor EC
Synonyms: TFEC, bHLHe34, Tcfec
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 21426
Homologene: 32148
Phactr3
Name: phosphatase and actin regulator 3
Synonyms: scapinin, 1500003N10Rik, 4930415A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74189
Homologene: 14482
Gm12886
Name: predicted gene 12886
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 666921
Homologene: 111034
Trem3
Name: triggering receptor expressed on myeloid cells 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 58218
VEGA: 17
Homologene: 87012
Irf2bp2
Name: interferon regulatory factor 2 binding protein 2
Synonyms: E130305N23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 270110
Homologene: 34290
Gm6003
Name: predicted gene 6003
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 102637838
Homologene: 141213
Pcdhgb6
Name: protocadherin gamma subfamily B, 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93703
HGNC: HGNC:8713
Homologene: 49573
RP23-75P5.3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Heatr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Mars2
Name: methionine-tRNA synthetase 2 (mitochondrial)
Synonyms: C730026E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 212679
Homologene: 6009
Gm16564
Name: predicted gene 16564
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 34,732,124 bp
  • T to A, chromosome 1 at 55,237,862 bp
  • T to A, chromosome 1 at 74,548,224 bp
  • T to C, chromosome 1 at 74,560,421 bp
  • T to A, chromosome 1 at 136,070,970 bp
  • T to C, chromosome 1 at 178,917,527 bp
  • A to T, chromosome 2 at 5,354,704 bp
  • A to T, chromosome 2 at 86,594,228 bp
  • G to A, chromosome 2 at 91,555,297 bp
  • G to T, chromosome 2 at 114,049,608 bp
  • T to G, chromosome 2 at 120,186,382 bp
  • A to T, chromosome 2 at 157,463,038 bp
  • T to C, chromosome 2 at 167,050,316 bp
  • A to C, chromosome 2 at 178,283,172 bp
  • G to A, chromosome 3 at 84,967,545 bp
  • A to G, chromosome 3 at 135,247,000 bp
  • A to C, chromosome 4 at 40,737,401 bp
  • T to A, chromosome 4 at 43,685,760 bp
  • T to G, chromosome 4 at 74,357,339 bp
  • T to C, chromosome 4 at 112,087,042 bp
  • T to G, chromosome 4 at 115,064,722 bp
  • T to C, chromosome 4 at 121,416,683 bp
  • A to G, chromosome 4 at 123,860,353 bp
  • T to C, chromosome 4 at 128,369,088 bp
  • C to T, chromosome 4 at 136,933,464 bp
  • A to G, chromosome 4 at 154,323,353 bp
  • T to C, chromosome 5 at 14,675,505 bp
  • T to C, chromosome 5 at 90,283,120 bp
  • T to A, chromosome 5 at 108,801,704 bp
  • C to T, chromosome 5 at 129,202,531 bp
  • A to G, chromosome 5 at 137,736,022 bp
  • T to A, chromosome 5 at 139,184,685 bp
  • G to A, chromosome 6 at 16,834,125 bp
  • T to A, chromosome 6 at 18,868,021 bp
  • A to G, chromosome 6 at 40,796,545 bp
  • C to A, chromosome 7 at 24,275,668 bp
  • T to A, chromosome 7 at 25,081,313 bp
  • G to T, chromosome 7 at 25,697,230 bp
  • A to C, chromosome 7 at 33,165,586 bp
  • G to T, chromosome 7 at 118,833,897 bp
  • GCTCCTCCTCCTCCTCCT to GCTCCTCCTCCTCCT, chromosome 7 at 127,558,310 bp
  • A to G, chromosome 7 at 128,205,980 bp
  • T to C, chromosome 8 at 14,846,679 bp
  • A to G, chromosome 8 at 15,106,459 bp
  • A to T, chromosome 8 at 47,493,345 bp
  • A to T, chromosome 8 at 62,023,261 bp
  • C to T, chromosome 8 at 123,274,338 bp
  • T to A, chromosome 8 at 126,591,255 bp
  • T to C, chromosome 10 at 50,711,025 bp
  • A to G, chromosome 10 at 80,006,568 bp
  • T to A, chromosome 10 at 84,844,300 bp
  • G to A, chromosome 11 at 4,043,375 bp
  • A to G, chromosome 11 at 20,239,333 bp
  • A to G, chromosome 11 at 31,365,326 bp
  • G to A, chromosome 11 at 98,101,766 bp
  • T to G, chromosome 12 at 73,045,934 bp
  • G to A, chromosome 12 at 100,500,117 bp
  • T to G, chromosome 14 at 16,409,189 bp
  • A to G, chromosome 14 at 30,900,968 bp
  • G to T, chromosome 14 at 32,661,871 bp
  • G to T, chromosome 14 at 75,732,951 bp
  • C to T, chromosome 15 at 6,842,894 bp
  • C to A, chromosome 15 at 8,171,798 bp
  • T to A, chromosome 15 at 23,226,783 bp
  • C to T, chromosome 15 at 58,640,226 bp
  • G to T, chromosome 15 at 75,747,736 bp
  • G to A, chromosome 15 at 101,487,999 bp
  • A to G, chromosome 15 at 102,130,364 bp
  • A to C, chromosome 15 at 102,252,551 bp
  • A to T, chromosome 16 at 87,402,024 bp
  • T to C, chromosome 16 at 90,788,146 bp
  • T to C, chromosome 17 at 17,911,083 bp
  • A to C, chromosome 17 at 48,249,611 bp
  • C to A, chromosome 17 at 53,426,275 bp
  • T to A, chromosome 17 at 57,052,740 bp
  • T to C, chromosome 17 at 74,499,094 bp
  • A to G, chromosome 18 at 37,676,881 bp
  • T to C, chromosome 19 at 8,778,208 bp
  • T to A, chromosome 19 at 28,357,875 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
(Deceased) Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4581 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
041802-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.