Strain Name:
C57BL/6J-MtgxR4607Btlr/Mmmh
Stock Number:
041818-MU
Citation ID:
RRID:MMRRC_041818-MU
Other Names:
R4607 (G1), C57BL/6J-MtgxR4607Btlr
Major Collection:

Gene Information

Chrna9
Name: cholinergic receptor, nicotinic, alpha polypeptide 9
Synonyms: Acra9, Gm8311, 2410015I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231252
Homologene: 9729
Pcdh9
Name: protocadherin 9
Synonyms: C530050I23Rik, LOC382930, C630029H24Rik, 1500001L12Rik, A730003J17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 211712
HGNC: HGNC:8661
Homologene: 10698
Slit1
Name: slit guidance ligand 1
Synonyms: Slil1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 20562
Homologene: 2302
Tlk2
Name: tousled-like kinase 2 (Arabidopsis)
Synonyms: PKUalpha, protein kinase U-alpha, 4933403M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 24086
Homologene: 4993
Uba2
Name: ubiquitin-like modifier activating enzyme 2
Synonyms: Uble1b, anthracycline-associated resistance, Arx, UBA2, SAE2, Sumo-1 activating enzyme subunit 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 50995
Homologene: 4018
Eif4g3
Name: eukaryotic translation initiation factor 4 gamma, 3
Synonyms: G1-419-52, 1500002J22Rik, repro8, 4930523M17Rik, eIF4GII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230861
HGNC: HGNC:3298
Homologene: 2789
Ipo11
Name: importin 11
Synonyms: 1700081H05Rik, 2510001A17Rik, Ranbp11, E330021B14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 76582
Homologene: 7089
Dlgap5
Name: DLG associated protein 5
Synonyms: Dlg7, Hurp, C86398
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 218977
Homologene: 8840
Wdr7
Name: WD repeat domain 7
Synonyms: TRAG, TGF-beta resistance associated gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 104082
VEGA: 18
Homologene: 11408
Tenm2
Name: teneurin transmembrane protein 2
Synonyms: D3Bwg1534e, 9330187F13Rik, Odz2, Ten-m2, 2610040L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 23964
Homologene: 22672
Dsg4
Name: desmoglein 4
Synonyms: lah, CDHF13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 16769
Homologene: 65341
Nrip1
Name: nuclear receptor interacting protein 1
Synonyms: 6030458L20Rik, 8430438I05Rik, RIP140
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 268903
HGNC: HGNC:8001
Homologene: 2606
Uty
Name: ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
Synonyms: Hydb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
NCBI: 22290
Leng8
Name: leukocyte receptor cluster (LRC) member 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232798
Homologene: 13612
Adgra3
Name: adhesion G protein-coupled receptor A3
Synonyms: 3830613O22Rik, Tem5-like, Gpr125
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 70693
Homologene: 19235
Hhip
Name: Hedgehog-interacting protein
Synonyms: Hhip1, Hip, Hip1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 15245
Homologene: 32469
Gna14
Name: guanine nucleotide binding protein, alpha 14
Synonyms: G alpha 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 14675
VEGA: 19
HGNC: HGNC:4382
Homologene: 68386
Map3k2
Name: mitogen-activated protein kinase kinase kinase 2
Synonyms: MEK kinase 2, 9630061B06Rik, Mekk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 26405
VEGA: 18
HGNC: HGNC:6854
Homologene: 74576
Fmnl2
Name: formin-like 2
Synonyms: man, 5430425K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71409
Homologene: 70871
Memo1
Name: mediator of cell motility 1
Synonyms: 0610016J10Rik, D930048L02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 76890
VEGA: 17
Homologene: 6272
Reg3g
Name: regenerating islet-derived 3 gamma
Synonyms: RegIII (gamma)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 19695
Homologene: 128216
Rdx
Name: radixin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 19684
VEGA: 9
HGNC: HGNC:9944
Homologene: 37707
Aldh1a1
Name: aldehyde dehydrogenase family 1, subfamily A1
Synonyms: ALDH1, E1, Raldh1, Ahd-2, Ahd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 11668
HGNC: HGNC:402
Homologene: 110441
Ints10
Name: integrator complex subunit 10
Synonyms: 4921521J11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 70885
Homologene: 10029
Zfand4
Name: zinc finger, AN1-type domain 4
Synonyms: Anubl1, 2810002D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 67492
VEGA: 6
Homologene: 18373
Strc
Name: stereocilin
Synonyms: DFNB16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 140476
Homologene: 15401
Mink1
Name: misshapen-like kinase 1 (zebrafish)
Synonyms: Map4k6, MINK, Misshapen/NIKs-related kinase, Ysk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 50932
Homologene: 56762
Acss3
Name: acyl-CoA synthetase short-chain family member 3
Synonyms: 8430416H19Rik, LOC380660
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 380660
Homologene: 11587
Bbs10
Name: Bardet-Biedl syndrome 10 (human)
Synonyms: 1300007O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71769
VEGA: 10
Homologene: 49781
Tmem132c
Name: transmembrane protein 132C
Synonyms: 2810482M11Rik, 4632425D07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 208213
Homologene: 76567
Fes
Name: feline sarcoma oncogene
Synonyms: c-fes
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 14159
HGNC: HGNC:3657
Homologene: 37563
Rxfp1
Name: relaxin/insulin-like family peptide receptor 1
Synonyms: Lgr7, LOC381489
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 381489
Homologene: 11007
Fam187b
Name: family with sequence similarity 187, member B
Synonyms: 1700020B09Rik, Tmem162
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 76415
Homologene: 138431
P2ry6
Name: pyrimidinergic receptor P2Y, G-protein coupled, 6
Synonyms: P2Y6, 2010204J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233571
HGNC: HGNC:8543
Homologene: 14289
Klk13
Name: kallikrein related-peptidase 13
Synonyms: mGk-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 626834
HGNC: HGNC:6361
Homologene: 56714
Nostrin
Name: nitric oxide synthase trafficker
Synonyms: mDaIP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329416
Homologene: 43142
Myrf
Name: myelin regulatory factor
Synonyms: LOC386531, Gm98, LOC225908
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225908
HGNC: HGNC:1181
Homologene: 32167
Pgghg
Name: protein glucosylgalactosylhydroxylysine glucosidase
Synonyms: Athl1, 5730511L01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 212974
Homologene: 16023
Zfp512b
Name: zinc finger protein 512B
Synonyms: LOC269401, Znf512b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 269401
Homologene: 69314
Olfr1219
Name: olfactory receptor 1219
Synonyms: GA_x6K02T2Q125-50555603-50554668, MOR233-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258901
Homologene: 27292
Gsg1l
Name: GSG1-like
Synonyms: C230098I05Rik, G630023A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 269994
Homologene: 78152
Gm906
Name: predicted gene 906
Synonyms: LOC380882
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 380882
VEGA: 13
Homologene: 134512
Fam161a
Name: family with sequence similarity 161, member A
Synonyms: 4930430E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 73873
Homologene: 19131
Cpeb3
Name: cytoplasmic polyadenylation element binding protein 3
Synonyms: 4831444O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 208922
Homologene: 40992
Nelfcd
Name: negative elongation factor complex member C/D, Th1l
Synonyms: 2410003I03Rik, trihydrophobin 1, Th1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 57314
Homologene: 9496
Zbtb42
Name: zinc finger and BTB domain containing 42
Synonyms: Gm5188, simiRP58
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 382639
Homologene: 20003
Olfr538
Name: olfactory receptor 538
Synonyms: GA_x6K02T2PBJ9-42723314-42724246, MOR253-12P, MOR253-13P, Olfr1523-ps1, Olfr1553-ps1, MOR253-10P, MOR253-13P, MOR253-12P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258201
Homologene: 110491
Olfr365
Name: olfactory receptor 365
Synonyms: GA_x6K02T2NLDC-33885305-33886243, MOR138-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258656
Homologene: 74156
Tmem74
Name: transmembrane protein 74
Synonyms: B230382K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239408
VEGA: 15
Homologene: 17684
Olfr303
Name: olfactory receptor 303
Synonyms: GA_x6K02T2NHDJ-9712819-9713778, MOR104-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258612
Homologene: 105157
Ccnl1
Name: cyclin L1
Synonyms: ania-6a, 2610030E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 56706
Homologene: 10541
Erlin1
Name: ER lipid raft associated 1
Synonyms: Spfh1, 2810439N09Rik, Keo4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226144
Homologene: 4716
Fpgt
Name: fucose-1-phosphate guanylyltransferase
Synonyms: 1700016E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 75540
HGNC: HGNC:3825
Homologene: 2847
Olfr753-ps1
Name: olfactory receptor 753, pseudogene 1
Synonyms: MOR256-38, GA_x6K02T2PSCP-1611898-1610960
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258052
Gm26657
Name: predicted gene, 26657
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Trbv24
Name: T cell receptor beta, variable 24
Synonyms: Tcrb-V17, Tcrb-V3.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 100124689
Trav15-1-dv6-1
Name: T cell receptor alpha variable 15-1-DV6-1
Synonyms: Gm16591
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 386446
Pcdhga6
Name: protocadherin gamma subfamily A, 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93714
HGNC: HGNC:8704
Homologene: 129611
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 2 at 37,202,082 bp
  • T to A, chromosome 2 at 53,103,716 bp
  • G to A, chromosome 2 at 69,183,899 bp
  • G to T, chromosome 2 at 89,074,312 bp
  • T to A, chromosome 2 at 121,372,945 bp
  • T to A, chromosome 2 at 174,423,162 bp
  • C to A, chromosome 2 at 181,588,774 bp
  • C to T, chromosome 3 at 65,946,710 bp
  • T to C, chromosome 3 at 79,686,889 bp
  • G to A, chromosome 3 at 155,086,696 bp
  • C to A, chromosome 4 at 56,741,114 bp
  • G to T, chromosome 4 at 138,126,458 bp
  • A to C, chromosome 5 at 49,970,739 bp
  • A to G, chromosome 5 at 65,976,735 bp
  • G to A, chromosome 5 at 127,551,571 bp
  • T to C, chromosome 6 at 41,218,401 bp
  • T to A, chromosome 6 at 78,467,503 bp
  • T to A, chromosome 6 at 116,328,234 bp
  • T to A, chromosome 7 at 4,144,797 bp
  • T to A, chromosome 7 at 30,977,745 bp
  • T to C, chromosome 7 at 34,154,596 bp
  • C to A, chromosome 7 at 43,713,860 bp
  • G to A, chromosome 7 at 80,387,211 bp
  • A to T, chromosome 7 at 86,394,510 bp
  • A to G, chromosome 7 at 100,938,304 bp
  • T to A, chromosome 7 at 125,958,549 bp
  • A to G, chromosome 7 at 140,574,641 bp
  • T to C, chromosome 7 at 140,943,433 bp
  • G to A, chromosome 8 at 68,810,619 bp
  • C to T, chromosome 8 at 79,997,563 bp
  • T to A, chromosome 9 at 52,068,837 bp
  • T to A, chromosome 10 at 106,967,029 bp
  • T to G, chromosome 10 at 111,300,820 bp
  • A to G, chromosome 10 at 111,301,134 bp
  • G to A, chromosome 11 at 23,020,710 bp
  • G to A, chromosome 11 at 36,171,381 bp
  • A to G, chromosome 11 at 70,606,067 bp
  • T to A, chromosome 11 at 105,255,018 bp
  • C to T, chromosome 12 at 112,680,542 bp
  • G to A, chromosome 13 at 50,245,506 bp
  • A to G, chromosome 13 at 106,900,811 bp
  • A to G, chromosome 14 at 47,413,018 bp
  • T to A, chromosome 14 at 53,560,054 bp
  • T to A, chromosome 14 at 93,015,573 bp
  • G to T, chromosome 15 at 43,867,158 bp
  • T to C, chromosome 16 at 76,293,032 bp
  • A to T, chromosome 17 at 37,170,282 bp
  • G to A, chromosome 17 at 74,258,461 bp
  • C to T, chromosome 18 at 20,471,245 bp
  • T to C, chromosome 18 at 32,199,977 bp
  • A to G, chromosome 18 at 37,708,618 bp
  • C to T, chromosome 18 at 63,777,580 bp
  • G to T, chromosome 19 at 10,229,067 bp
  • A to G, chromosome 19 at 16,533,711 bp
  • A to T, chromosome 19 at 20,621,687 bp
  • A to G, chromosome 19 at 37,174,839 bp
  • C to A, chromosome 19 at 41,616,793 bp
  • C to T, chromosome 19 at 44,063,035 bp
  • C to T, chromosome Y at 1,131,134 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4607 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
041818-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.