Strain Name:
C57BL/6J-MtgxR4633Btlr/Mmmh
Stock Number:
041898-MU
Citation ID:
RRID:MMRRC_041898-MU
Other Names:
R4633 (G1), C57BL/6J-MtgxR4633Btlr
Major Collection:

Gene Information

Alg10b
Name: asparagine-linked glycosylation 10B (alpha-1,2-glucosyltransferase)
Synonyms: LOC380959, Deaf1, nse5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 380959
VEGA: 15
Homologene: 6030
Mrtfb
Name: myocardin related transcription factor B
Synonyms: Mrtfb, Mkl2, Gt4-1, MRTF-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 239719
Homologene: 40917
Krt5
Name: keratin 5
Synonyms: 3300001P10Rik, Tfip8, Krt2-5, K5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 110308
HGNC: HGNC:6442
Homologene: 55461
Dst
Name: dystonin
Synonyms: A830042E19Rik, 2310001O04Rik, Macf2, bullous pemphigoid antigen 1, BPAG1-n, BPAG1, athetoid, Bpag, ah, bullous pemphigoid antigen 1, Bpag1, nmf339, nmf203
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Trim59
Name: tripartite motif-containing 59
Synonyms: 2310035M22Rik, TSBF1, 2700022F13Rik, Mrf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 66949
Homologene: 32644
Utp20
Name: UTP20 small subunit processome component
Synonyms: DRIM, 3830408P06Rik, mDRIM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 70683
VEGA: 10
Homologene: 38373
Rps19
Name: ribosomal protein S19
Synonyms: Dsk3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 20085
Homologene: 37416
Map1b
Name: microtubule-associated protein 1B
Synonyms: Mtap5, Mtap-5, MAP5, Mtap1b, LC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 17755
VEGA: 13
HGNC: HGNC:6836
Homologene: 38111
Lrp2
Name: low density lipoprotein receptor-related protein 2
Synonyms: D230004K18Rik, b2b1625.2Clo, Gp330, Megalin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 14725
HGNC: HGNC:6694
Homologene: 20952
Rbpms2
Name: RNA binding protein with multiple splicing 2
Synonyms: 2400008B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 71973
VEGA: 9
Homologene: 49895
Gpr139
Name: G protein-coupled receptor 139
Synonyms: GPRg1, LOC209776
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 209776
Homologene: 45860
Usp48
Name: ubiquitin specific peptidase 48
Synonyms: Usp31, 2810449C13Rik, D330022K21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 170707
Homologene: 12988
Hdlbp
Name: high density lipoprotein (HDL) binding protein
Synonyms: D1Ertd101e, 1110005P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 110611
HGNC: HGNC:4857
Homologene: 38035
Nomo1
Name: nodal modulator 1
Synonyms: D7Ertd156e, Nomo, PM5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 211548
Homologene: 13810
Prpf4b
Name: pre-mRNA processing factor 4B
Synonyms: Prp4, Prp4k, Prpk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 19134
VEGA: 13
Homologene: 134085
Trim24
Name: tripartite motif-containing 24
Synonyms: Tif1a, D430004I05Rik, A130082H20Rik, TIF1alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 21848
Homologene: 20830
Tet2
Name: tet methylcytosine dioxygenase 2
Synonyms: Ayu17-449, E130014J05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 214133
Homologene: 49498
Rsf1
Name: remodeling and spacing factor 1
Synonyms: XAP8, p325, 4832420A03Rik, C030033M12Rik, Hbxap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233532
Homologene: 41142
Fkbp15
Name: FK506 binding protein 15
Synonyms: C430014M02Rik, FKBP133
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 338355
Homologene: 28743
Parp4
Name: poly (ADP-ribose) polymerase family, member 4
Synonyms: Adprtl1, VPARP, C030027K23Rik, E230037B21Rik, VAULT3, PH5P, p193
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 328417
HGNC: HGNC:271
Homologene: 124423
Fanci
Name: Fanconi anemia, complementation group I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 208836
Homologene: 49530
Stk3
Name: serine/threonine kinase 3
Synonyms: Mst2, MST, 0610042I06Rik, mess1, Ste20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 56274
Homologene: 48420
Vps18
Name: VPS18 CORVET/HOPS core subunit
Synonyms: 9930024E13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228545
Homologene: 13302
Rcc1
Name: regulator of chromosome condensation 1
Synonyms: Chc1, 4931417M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100088
HGNC: HGNC:1913
Homologene: 55567
Lama1
Name: laminin, alpha 1
Synonyms: Lama
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 16772
VEGA: 17
HGNC: HGNC:6481
Homologene: 21146
Glg1
Name: golgi apparatus protein 1
Synonyms: ESL-1, CFR, MG160, CFR-1, Selel, MG-160
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 20340
HGNC: HGNC:4316
Homologene: 7533
Zfp410
Name: zinc finger protein 410
Synonyms: D12Ertd748e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 52708
VEGA: 12
Homologene: 10918
Selenof
Name: selenoprotein F
Synonyms: Sep15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 93684
Homologene: 3145
Hectd4
Name: HECT domain E3 ubiquitin protein ligase 4
Synonyms: Gm15800
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 269700
Homologene: 28297
Pla2g15
Name: phospholipase A2, group XV
Synonyms: Lpla2, LLPL, C87498, Lypla3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 192654
Homologene: 8200
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 94109
Homologene: 69536
Abcb6
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 6
Synonyms: 1200005B17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 74104
HGNC: HGNC:47
Homologene: 11375
Abca3
Name: ATP-binding cassette, sub-family A (ABC1), member 3
Synonyms: ABC-C, Abc3, 1810036E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 27410
HGNC: HGNC:33
Homologene: 37437
Olfr59
Name: olfactory receptor 59
Synonyms: GA_x6K02T2P1NL-4434429-4435400, IH3, MOR133-3P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 18359
HGNC: null
Homologene: 73924
Polq
Name: polymerase (DNA directed), theta
Synonyms: A430110D14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 77782
HGNC: HGNC:9186
Homologene: 32727
Uspl1
Name: ubiquitin specific peptidase like 1
Synonyms: E430026A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231915
Homologene: 4235
Klra13-ps
Name: killer cell lectin-like receptor subfamily A, member 13, pseudogene
Synonyms: Ly49M
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16631
HGNC: null
Homologene: null
Gm884
Name: predicted gene 884
Synonyms: LOC380730
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 380730
Homologene: 134511
Psma1
Name: proteasome (prosome, macropain) subunit, alpha type 1
Synonyms: HC2, C2, Pros-30
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 26440
HGNC: HGNC:9530
Homologene: 2080
Lrriq1
Name: leucine-rich repeats and IQ motif containing 1
Synonyms: LOC380658, 4930503E15Rik, Gm1557
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 74978
Homologene: 46007
Fzd1
Name: frizzled class receptor 1
Synonyms: FZ-1, Fz1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 14362
HGNC: HGNC:4038
Homologene: 20750
1810064F22Rik
Name: RIKEN cDNA 1810064F22 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 69862
HGNC: null
Homologene: null
Rev3l
Name: REV3 like, DNA directed polymerase zeta catalytic subunit
Synonyms: Rev, Sez4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 19714
HGNC: HGNC:9968
Homologene: 48147
Olfr1362
Name: olfactory receptor 1362
Synonyms: GA_x6K02T2QHY8-11617756-11618682, GA_x6K02T2QHY8-11628399-11628868, Olfr1363-ps1, MOR256-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 258739
HGNC: null
Homologene: 105885
Phykpl
Name: 5-phosphohydroxy-L-lysine phospholyase
Synonyms: Agxt2l2, 2900006B13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 72947
Homologene: 75268
Ces1c
Name: carboxylesterase 1C
Synonyms: Es-1, Es-N, Es1, Es-4, Ces-N, Ee-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 13884
HGNC: HGNC:1863
Homologene: 117484
Zswim8
Name: zinc finger SWIM-type containing 8
Synonyms: 2310021P13Rik, 4832404P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 268721
VEGA: 14
Homologene: 34313
Ttc28
Name: tetratricopeptide repeat domain 28
Synonyms: 2310015L07Rik, TPRBK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 209683
Homologene: 41023
Itga10
Name: integrin, alpha 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 213119
HGNC: HGNC:6135
Homologene: 2697
Cyp3a59
Name: cytochrome P450, family 3, subfamily a, polypeptide 59
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100041449
HGNC: null
Homologene: 135775
Erbb2
Name: erb-b2 receptor tyrosine kinase 2
Synonyms: l11Jus8, ErbB-2, HER-2, c-erbB2, c-neu, Neu, HER2, Neu oncogene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 13866
HGNC: HGNC:3430
Homologene: 3273
Tm9sf1
Name: transmembrane 9 superfamily member 1
Synonyms: 1200014D02Rik, MP70
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 74140
Homologene: 4671
Olfr982
Name: olfactory receptor 982
Synonyms: GA_x6K02T2PVTD-33772307-33773260, MOR223-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258853
VEGA: 9
Homologene: 17415
Myom3
Name: myomesin family, member 3
Synonyms: 8430427K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242702
Homologene: 19432
Alkbh2
Name: alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase
Synonyms: Abh2, mABH2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231642
Homologene: 18393
Ccdc130
Name: coiled-coil domain containing 130
Synonyms: 4930527D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 67736
Homologene: 12183
Krt1
Name: keratin 1
Synonyms: Krt-2.1, Krt2-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 16678
VEGA: 15
HGNC: HGNC:6412
Homologene: 38146
Tas2r102
Name: taste receptor, type 2, member 102
Synonyms: Tas2r2, mt2r51, STC 9-7, mGR02
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 387339
HGNC: null
Homologene: 41543
Cd44
Name: CD44 antigen
Synonyms: Pgp-1, Ly-24, HERMES
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 12505
HGNC: HGNC:1681
Homologene: 508
Usp17la
Name: ubiquitin specific peptidase 17-like A
Synonyms: Dub1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 13531
HGNC: null
Homologene: 131315
Olfr168
Name: olfactory receptor 168
Synonyms: GA_x54KRFPKG5P-15979009-15978071, MOR271-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 258354
Homologene: 128057
Slc16a11
Name: solute carrier family 16 (monocarboxylic acid transporters), member 11
Synonyms: MNCb-2717
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216867
Homologene: 27409
Taar8b
Name: trace amine-associated receptor 8B
Synonyms: LOC382348
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 382348
Homologene: 77586
Krtap4-9
Name: keratin associated protein 4-9
Synonyms: OTTMUSG00000002198
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 665998
HGNC: null
Homologene: null
Mylk2
Name: myosin, light polypeptide kinase 2, skeletal muscle
Synonyms: 9830004H17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228785
Homologene: 13223
Cnot11
Name: CCR4-NOT transcription complex, subunit 11
Synonyms: 2410015L18Rik, D1Bwg0212e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 52846
Homologene: 9711
Tvp23a
Name: trans-golgi network vesicle protein 23A
Synonyms: Fam18a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 383103
Homologene: 19919
Erlin1
Name: ER lipid raft associated 1
Synonyms: Spfh1, Keo4, 2810439N09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226144
Homologene: 4716
Rhobtb1
Name: Rho-related BTB domain containing 1
Synonyms: 3110048G13Rik, 1700008H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 69288
Homologene: 8892
Tcrg-C4
Name: T cell receptor gamma, constant 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 107576
HGNC: null
Homologene: null
B4galt7
Name: xylosylprotein beta1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218271
HGNC: HGNC:930
Homologene: 5248
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 34,170,434 bp
  • G to T, chromosome 1 at 39,536,218 bp
  • A to T, chromosome 1 at 75,177,782 bp
  • A to G, chromosome 1 at 93,429,423 bp
  • T to A, chromosome 2 at 69,461,417 bp
  • T to G, chromosome 2 at 102,853,047 bp
  • T to C, chromosome 2 at 119,293,276 bp
  • T to C, chromosome 2 at 152,917,415 bp
  • G to T, chromosome 3 at 69,037,414 bp
  • A to G, chromosome 3 at 96,647,704 bp
  • T to A, chromosome 3 at 133,485,549 bp
  • C to T, chromosome 3 at 144,596,861 bp
  • T to C, chromosome 4 at 62,304,529 bp
  • G to T, chromosome 4 at 132,335,769 bp
  • T to G, chromosome 4 at 135,775,699 bp
  • A to G, chromosome 4 at 137,634,900 bp
  • A to T, chromosome 5 at 4,755,865 bp
  • C to T, chromosome 5 at 111,224,001 bp
  • C to T, chromosome 5 at 114,124,226 bp
  • C to A, chromosome 5 at 121,349,216 bp
  • T to C, chromosome 5 at 146,094,438 bp
  • A to G, chromosome 5 at 149,214,392 bp
  • T to A, chromosome 6 at 37,956,436 bp
  • T to G, chromosome 6 at 130,291,173 bp
  • T to A, chromosome 6 at 132,762,679 bp
  • G to T, chromosome 7 at 24,889,170 bp
  • A to G, chromosome 7 at 46,050,260 bp
  • T to C, chromosome 7 at 79,427,242 bp
  • GCG to GCGACGGCGACG, chromosome 7 at 97,579,907 bp
  • A to T, chromosome 7 at 104,860,221 bp
  • A to G, chromosome 7 at 114,271,134 bp
  • A to T, chromosome 7 at 119,144,405 bp
  • A to G, chromosome 8 at 16,002,620 bp
  • T to C, chromosome 8 at 84,260,395 bp
  • T to C, chromosome 8 at 93,118,386 bp
  • T to C, chromosome 8 at 106,160,255 bp
  • C to T, chromosome 8 at 111,177,644 bp
  • G to T, chromosome 9 at 22,197,194 bp
  • T to A, chromosome 9 at 40,074,334 bp
  • T to C, chromosome 9 at 65,651,636 bp
  • C to A, chromosome 10 at 24,092,252 bp
  • T to G, chromosome 10 at 39,846,186 bp
  • T to A, chromosome 10 at 69,249,613 bp
  • T to C, chromosome 10 at 88,752,952 bp
  • G to A, chromosome 10 at 103,200,563 bp
  • C to A, chromosome 11 at 51,593,608 bp
  • T to C, chromosome 11 at 70,216,379 bp
  • T to G, chromosome 11 at 74,289,294 bp
  • T to A, chromosome 11 at 98,432,988 bp
  • G to T, chromosome 11 at 99,785,554 bp
  • A to T, chromosome 11 at 103,619,131 bp
  • A to T, chromosome 12 at 84,325,736 bp
  • G to T, chromosome 13 at 19,352,287 bp
  • A to G, chromosome 13 at 21,611,228 bp
  • A to G, chromosome 13 at 34,900,442 bp
  • A to G, chromosome 13 at 55,608,750 bp
  • C to T, chromosome 13 at 99,434,942 bp
  • A to G, chromosome 14 at 20,718,823 bp
  • A to G, chromosome 14 at 55,641,203 bp
  • C to T, chromosome 14 at 56,647,591 bp
  • A to G, chromosome 15 at 34,958,928 bp
  • T to C, chromosome 15 at 90,228,294 bp
  • T to A, chromosome 15 at 101,711,607 bp
  • C to T, chromosome 15 at 101,846,187 bp
  • C to T, chromosome 16 at 10,427,045 bp
  • T to C, chromosome 16 at 13,379,873 bp
  • C to T, chromosome 16 at 19,530,284 bp
  • T to G, chromosome 16 at 37,048,542 bp
  • T to A, chromosome 17 at 24,387,529 bp
  • C to A, chromosome 17 at 67,798,584 bp
  • G to A, chromosome 19 at 44,040,765 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4633 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
041898-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.