Strain Name:
C57BL/6J-MtgxR4691Btlr/Mmmh
Stock Number:
041942-MU
Citation ID:
RRID:MMRRC_041942-MU
Other Names:
R4691 (G1), C57BL/6J-MtgxR4691Btlr
Major Collection:

Strain Information

Myo5a
Name: myosin VA
Synonyms: 9630007J19Rik, Myo5, MyoVA, Dbv, flail, MVa
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17918
HGNC: HGNC:7602
Homologene: 20100
Ap4e1
Name: adaptor-related protein complex AP-4, epsilon 1
Synonyms: 2310033A20Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 108011
HGNC: HGNC:573
Homologene: 22397
Dst
Name: dystonin
Synonyms: A830042E19Rik, nmf339, bullous pemphigoid antigen 1, Bpag1, 2310001O04Rik, Bpag, Macf2, BPAG1, BPAG1-n, athetoid, bullous pemphigoid antigen 1, ah, nmf203
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Epop
Name: elongin BC and polycomb repressive complex 2 associated protein
Synonyms: E130012A19Rik, E13
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 103551
Homologene: 82351
Pou5f1
Name: POU domain, class 5, transcription factor 1
Synonyms: Otf3, Oct3/4, Oct-3/4, Oct-4, Otf-3, Oct4, Otf3g, Oct-3, Otf3-rs7, Otf-4, Otf4
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18999
Homologene: 8422
Nkx2-1
Name: NK2 homeobox 1
Synonyms: thyroid transcription factor-1, Titf1, Ttf-1, tinman, thyroid-specific enhancer-binding protein, T/EBP
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 21869
Homologene: 2488
Vps13c
Name: vacuolar protein sorting 13C
Synonyms: C230055H22Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 320528
VEGA: 9
Homologene: 41188
Ccz1
Name: CCZ1 vacuolar protein trafficking and biogenesis associated
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231874
Homologene: 56717
Txnl1
Name: thioredoxin-like 1
Synonyms: 32kDa, TRP32
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 53382
VEGA: 18
Homologene: 3515
Ezr
Name: ezrin
Synonyms: Vil2, ezrin, cytovillin, p81
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22350
Homologene: 55740
Tet2
Name: tet methylcytosine dioxygenase 2
Synonyms: Ayu17-449, E130014J05Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 214133
Homologene: 49498
Ddias
Name: DNA damage-induced apoptosis suppressor
Synonyms: 4632434I11Rik, noxin
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74041
Homologene: 51655
Gins4
Name: GINS complex subunit 4
Synonyms: SLD5, 2810037C03Rik, 4933405K01Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 109145
Homologene: 5759
Gcfc2
Name: GC-rich sequence DNA binding factor 2
Synonyms: AW146020
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330361
HGNC: HGNC:1317
Homologene: 2411
Zfp617
Name: zinc finger protein 617
Synonyms: Zinc finger protein s11-6, Zfps11-6
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 170938
Homologene: 135689
Arel1
Name: apoptosis resistant E3 ubiquitin protein ligase 1
Synonyms: 1110018G07Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 68497
Homologene: 8885
Syt7
Name: synaptotagmin VII
Synonyms: B230112P13Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 54525
VEGA: 19
Homologene: 20889
Erap1
Name: endoplasmic reticulum aminopeptidase 1
Synonyms: Arts1, PILSAP, ERAAP
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 80898
VEGA: 13
Homologene: 56754
Robo3
Name: roundabout guidance receptor 3
Synonyms: Rig1, Rig-1, Robo3b, Rbig1, Robo3a
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 19649
Homologene: 32119
C2cd5
Name: C2 calcium-dependent domain containing 5
Synonyms: 5730419I09Rik, C030008B15Rik, CDP138
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 74741
Homologene: 8873
Zfp869
Name: zinc finger protein 869
Synonyms: U 2-7-1, 1200003I07Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 66869
VEGA: 8
Homologene: 134644
Pank2
Name: pantothenate kinase 2
Synonyms: 4933409I19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74450
Homologene: 65126
Pcx
Name: pyruvate carboxylase
Synonyms: Pc
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18563
VEGA: 19
HGNC: HGNC:8636
Homologene: 5422
Cables1
Name: CDK5 and Abl enzyme substrate 1
Synonyms: ik3-1, interactor-1 with cdk3
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 63955
VEGA: 18
Homologene: 11097
Qtrt2
Name: queuine tRNA-ribosyltransferase accessory subunit 2
Synonyms: Qtrtd1, 3110012M05Rik, 4930470H18Rik, Qrtr2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 106248
Homologene: 41576
Zscan22
Name: zinc finger and SCAN domain containing 22
Synonyms: Hkr2, D530006B18Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 232878
HGNC: HGNC:4929
Homologene: 68122
Pdgfd
Name: platelet-derived growth factor, D polypeptide
Synonyms: 1110003I09Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 71785
VEGA: 9
Homologene: 11875
Galnt12
Name: polypeptide N-acetylgalactosaminyltransferase 12
Synonyms: A630062B03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230145
Homologene: 11637
H2-T22
Name: histocompatibility 2, T region locus 22
Synonyms: H-2T17, H2-T17, H-2T22
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 15039
Homologene: 79525
Trpc6
Name: transient receptor potential cation channel, subfamily C, member 6
Synonyms: Trrp6, mtrp6
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22068
VEGA: 9
Homologene: 37944
Itgae
Name: integrin alpha E, epithelial-associated
Synonyms: alpha-E1, CD103
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16407
HGNC: HGNC:6147
Homologene: 113560
Ndufs7
Name: NADH:ubiquinone oxidoreductase core subunit S7
Synonyms: 1010001M04Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 75406
HGNC: HGNC:7714
Homologene: 11535
Pla2g4e
Name: phospholipase A2, group IVE
Synonyms: Pla2epsilon, 2310026J01Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 329502
Homologene: 65339
Abca13
Name: ATP-binding cassette, sub-family A member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268379
Homologene: 27991
Dnah10
Name: dynein, axonemal, heavy chain 10
Synonyms: Dnahc10
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56087
HGNC: HGNC:2941
Homologene: 25816
Zfp354a
Name: zinc finger protein 354A
Synonyms: Tcf17, kid1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 21408
Homologene: 55921
Agl
Name: amylo-1,6-glucosidase, 4-alpha-glucanotransferase
Synonyms: 9430004C13Rik, 1110061O17Rik, 9630046L06Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 77559
HGNC: HGNC:321
Homologene: 536
Cpne2
Name: copine II
Synonyms: 3322401K10Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234577
HGNC: HGNC:2315
Homologene: 27392
Sos2
Name: SOS Ras/Rho guanine nucleotide exchange factor 2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 20663
Homologene: 38253
Ankrd50
Name: ankyrin repeat domain 50
Synonyms: E430012K20Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99696
Homologene: 129859
Adamts2
Name: ADAM metallopeptidase with thrombospondin type 1 motif 2
Synonyms: hPCPNI, a disintegrin and metalloproteinase with thrombospondin repeats, procollagen N-proteinase, ADAM-TS2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216725
HGNC: HGNC:218
Homologene: 8597
Irf2
Name: interferon regulatory factor 2
Synonyms: 9830146E22Rik, Irf-2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 16363
HGNC: HGNC:6117
Homologene: 1659
Ceacam23
Name: CEA cell adhesion moleculen23
Synonyms: Gm5155
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381852
HGNC: HGNC:1819
Homologene: 115938
Vmn2r72
Name: vomeronasal 2, receptor 72
Synonyms: EG244114, Vmn2r72-ps
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 244114
Homologene: 115466
Inpp4b
Name: inositol polyphosphate-4-phosphatase, type II
Synonyms: E130107I17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234515
HGNC: HGNC:6075
Homologene: 20832
Dennd4b
Name: DENN domain containing 4B
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229541
Homologene: 28281
Kdr
Name: kinase insert domain protein receptor
Synonyms: Flk1, VEGFR2, Flk-1, VEGFR-2, vascular endothelial growth factor receptor- 2, orv, VEGF receptor-2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 16542
HGNC: HGNC:6307
Homologene: 55639
Sp140l1
Name: Sp140 nuclear body protein like 1
Synonyms: LOC381287, A530032D15Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381287
Homologene: 131208
Prdm9
Name: PR domain containing 9
Synonyms: repro7, Dsbc1, Rcr1, G1-419-29, Meisetz
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 213389
Homologene: 104139
Bag6
Name: BCL2-associated athanogene 6
Synonyms: D17H6S52E, 2410045D21Rik, G3, Scythe, Bat3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224727
Homologene: 3409
Ptk2b
Name: PTK2 protein tyrosine kinase 2 beta
Synonyms: Raftk, related adhesion focal tyrosine kinase, cellular adhesion kinase beta, E430023O05Rik, PYK2, proline-rich tyrosine kinase 2, CAKbeta, calcium-dependent tyrosine kinase
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 19229
HGNC: HGNC:9612
Homologene: 23001
Rad51ap1
Name: RAD51 associated protein 1
Synonyms: 2510006L10Rik, RAB22
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 19362
Homologene: 48436
Disc1
Name: disrupted in schizophrenia 1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244667
HGNC: HGNC:2888
Homologene: 10257
Tmem232
Name: transmembrane protein 232
Synonyms: E130009J12Rik, LOC381107
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 381107
VEGA: 17
Homologene: 54378
Vmn2r81
Name: vomeronasal 2, receptor 81
Synonyms: EC1-VR2, V2rf2, pheromone recepter
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216144
Homologene: 83483
Cyp2d9
Name: cytochrome P450, family 2, subfamily d, polypeptide 9
Synonyms: Cyp2d, testosterone 16alpha-hydroxylase, P450-2D
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 13105
VEGA: 15
Homologene: 86099
Eya4
Name: EYA transcriptional coactivator and phosphatase 4
Synonyms: B130023L16Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 14051
VEGA: 10
HGNC: HGNC:3522
Homologene: 3025
Mro
Name: maestro
Synonyms: 4930507C04Rik, 4933435E20Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 71263
Homologene: 41729
Grid1
Name: glutamate receptor, ionotropic, delta 1
Synonyms: GluRdelta1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 14803
HGNC: HGNC:4575
Homologene: 69017
St3gal2
Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 2
Synonyms: Siat5, ST3GalII
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 20444
Homologene: 5047
Ces1a
Name: carboxylesterase 1A
Synonyms: Gm4976
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244595
HGNC: HGNC:1863
Homologene: 134142
Or7e165
Name: olfactory receptor family 7 subfamily E member 165
Synonyms: IG6, MOR146-3, Olfr58, GA_x6K02T2PVTD-13523015-13523944, MOR146-7P
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18358
Homologene: 134093
Zfp84
Name: zinc finger protein 84
Synonyms: C86188, 4633401C23Rik, 2210410P13Rik, Zfp69, KRAB18
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74352
Homologene: 51858
Zfp663
Name: zinc finger protein 663
Synonyms: Gm1008, LOC381405
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 381405
Homologene: 128277
Stra6l
Name: STRA6-like
Synonyms: Rbpr2, 1300002K09Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 74152
Homologene: 81924
Sval2
Name: seminal vesicle antigen-like 2
Synonyms: SLP-M
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 84543
Homologene: 13055
Fam53c
Name: family with sequence similarity 53, member C
Synonyms: 2810012G03Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 66306
VEGA: 18
HGNC: HGNC:1336
Homologene: 9586
Pcdhgb5
Name: protocadherin gamma subfamily B, 5
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93702
HGNC: HGNC:8712
Homologene: 55773
Clca4
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Ccnb1-ps
Name: cyclin B1, pseudogene
Synonyms: Gm5593
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 434175
HGNC: HGNC:1579
Homologene: 68982
Vsig10l2
Name: V-set and immunoglobulin domain containing 10 like 2
Synonyms: Gm1113, LOC382069
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 115487164
Dnase1l1
Name: deoxyribonuclease 1-like 1
Synonyms: G4.8, Dnl1ll, 2310005K03Rik, Dnase1ll
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 69537
HGNC: HGNC:2957
Homologene: 4896
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 34,164,183 bp
  • C to T, chromosome 1 at 85,088,800 bp
  • T to C, chromosome 2 at 120,174,300 bp
  • T to C, chromosome 2 at 127,061,871 bp
  • T to A, chromosome 2 at 131,296,281 bp
  • G to T, chromosome 2 at 165,359,130 bp
  • A to G, chromosome 3 at 38,483,010 bp
  • A to G, chromosome 3 at 90,272,312 bp
  • G to A, chromosome 3 at 116,791,082 bp
  • T to A, chromosome 3 at 133,486,083 bp
  • G to A, chromosome 3 at 144,839,092 bp
  • G to A, chromosome 4 at 45,882,851 bp
  • T to C, chromosome 4 at 47,104,143 bp
  • T to C, chromosome 5 at 75,944,599 bp
  • A to G, chromosome 5 at 124,775,517 bp
  • A to T, chromosome 5 at 143,991,562 bp
  • C to T, chromosome 6 at 41,864,286 bp
  • T to A, chromosome 6 at 81,941,427 bp
  • A to G, chromosome 6 at 126,927,553 bp
  • A to G, chromosome 6 at 143,030,148 bp
  • C to T, chromosome 7 at 12,906,561 bp
  • T to A, chromosome 7 at 17,908,966 bp
  • T to C, chromosome 7 at 29,777,080 bp
  • T to A, chromosome 7 at 42,106,092 bp
  • A to T, chromosome 7 at 85,737,911 bp
  • T to A, chromosome 7 at 92,858,816 bp
  • T to A, chromosome 8 at 23,237,059 bp
  • T to A, chromosome 8 at 46,846,187 bp
  • A to T, chromosome 8 at 69,706,863 bp
  • A to T, chromosome 8 at 71,932,815 bp
  • A to T, chromosome 8 at 82,122,653 bp
  • T to C, chromosome 8 at 93,032,659 bp
  • A to T, chromosome 8 at 94,558,221 bp
  • C to T, chromosome 8 at 110,957,785 bp
  • T to C, chromosome 8 at 125,148,447 bp
  • C to T, chromosome 9 at 6,288,556 bp
  • A to C, chromosome 9 at 8,652,978 bp
  • T to C, chromosome 9 at 19,783,382 bp
  • T to C, chromosome 9 at 35,516,862 bp
  • T to C, chromosome 9 at 37,425,218 bp
  • T to C, chromosome 9 at 67,952,935 bp
  • A to G, chromosome 9 at 75,180,156 bp
  • T to A, chromosome 10 at 23,140,068 bp
  • C to T, chromosome 10 at 79,293,377 bp
  • C to A, chromosome 10 at 80,253,696 bp
  • A to T, chromosome 11 at 9,434,195 bp
  • G to T, chromosome 11 at 50,756,696 bp
  • A to G, chromosome 11 at 51,070,237 bp
  • G to T, chromosome 11 at 73,119,519 bp
  • C to T, chromosome 11 at 97,628,893 bp
  • T to A, chromosome 12 at 56,533,565 bp
  • C to T, chromosome 12 at 69,616,328 bp
  • A to T, chromosome 12 at 84,930,249 bp
  • T to C, chromosome 12 at 115,593,309 bp
  • T to C, chromosome 13 at 74,673,692 bp
  • A to G, chromosome 14 at 35,569,557 bp
  • C to T, chromosome 14 at 66,157,069 bp
  • A to G, chromosome 15 at 82,455,832 bp
  • T to A, chromosome 16 at 43,880,351 bp
  • T to C, chromosome 17 at 6,759,562 bp
  • A to G, chromosome 17 at 15,553,378 bp
  • T to A, chromosome 17 at 35,139,248 bp
  • T to A, chromosome 17 at 35,506,131 bp
  • GTTTT to GTTT, chromosome 17 at 36,041,570 bp
  • T to C, chromosome 17 at 65,265,242 bp
  • C to T, chromosome 18 at 11,840,523 bp
  • A to C, chromosome 18 at 34,768,690 bp
  • G to T, chromosome 18 at 37,732,689 bp
  • A to G, chromosome 18 at 63,671,679 bp
  • A to T, chromosome 18 at 73,873,326 bp
  • T to A, chromosome 19 at 4,619,477 bp
  • T to A, chromosome 19 at 10,426,481 bp
  • C to T, chromosome X at 74,277,038 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4691 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
041942-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.