Strain Name:
C57BL/6J-MtgxR4693Btlr/Mmmh
Stock Number:
041944-MU
Citation ID:
RRID:MMRRC_041944-MU
Other Names:
R4693 (G1), C57BL/6J-MtgxR4693Btlr
Major Collection:

Strain Information

Pax3
Name: paired box 3
Synonyms: Pax-3, Splchl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18505
HGNC: HGNC:8617
Homologene: 22494
Dspp
Name: dentin sialophosphoprotein
Synonyms: Dmp3, Dpp, Dsp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 666279
HGNC: HGNC:3054
Cyp19a1
Name: cytochrome P450, family 19, subfamily a, polypeptide 1
Synonyms: Int-5, Int5, aromatase, Ar, Cyp19, ArKO, p450arom
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 13075
VEGA: 9
HGNC: HGNC:2594
Homologene: 30955
Slamf6
Name: SLAM family member 6
Synonyms: SF2000, NTB-A, KAL1b, KAL1, Ly108
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 30925
Homologene: 49945
Ptprf
Name: protein tyrosine phosphatase, receptor type, F
Synonyms: LAR, RPTP-LAR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 19268
HGNC: HGNC:9670
Homologene: 20623
Lrrc2
Name: leucine rich repeat containing 2
Synonyms: 2400002D05Rik, 4933431K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74249
Homologene: 23454
Scn8a
Name: sodium channel, voltage-gated, type VIII, alpha
Synonyms: med, seal, motor end-plate disease, nmf2, ataxia 3, mnd2, mnd-2, C630029C19Rik, nmf58, NaCh6, Nav1.6, nmf335, NMF335, nur14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 20273
Homologene: 7927
Tcf12
Name: transcription factor 12
Synonyms: ME1, ALF1, HEB, HTF4, HTF-4, REB, bHLHb20, HEBAlt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 21406
Homologene: 40774
Abcg8
Name: ATP binding cassette subfamily G member 8
Synonyms: 1300003C16Rik, Sterolin-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 67470
Homologene: 23361
Tiam1
Name: T cell lymphoma invasion and metastasis 1
Synonyms: D16Ium10, D16Ium10e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 21844
Homologene: 2443
Ipo8
Name: importin 8
Synonyms: OM-1, 6230418K12Rik, Om1, C130009K11Rik, Ranbp8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 320727
HGNC: HGNC:9853
Homologene: 48430
Hmg20b
Name: high mobility group 20B
Synonyms: Smarce1r, Hmgx2, BRCA2-associated factor 35, BRAF35, Hmgxb2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 15353
HGNC: HGNC:5002
Homologene: 74949
Dclk2
Name: doublecortin-like kinase 2
Synonyms: 6330415M09Rik, Click-II, Dcamkl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 70762
Homologene: 69431
Gosr2
Name: golgi SNAP receptor complex member 2
Synonyms: membrin, GS27, SNARE, 2310032N09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 56494
HGNC: HGNC:4431
Homologene: 37907
Ncbp3
Name: nuclear cap binding subunit 3
Synonyms: 1200014J11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 66874
Homologene: 10231
Tox
Name: thymocyte selection-associated high mobility group box
Synonyms: 1700007F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 252838
Homologene: 8822
Dab1
Name: disabled 1
Synonyms: C630028C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13131
HGNC: HGNC:2661
Homologene: 32084
Mlh1
Name: mutL homolog 1
Synonyms: colon cancer, nonpolyposis type 2, 1110035C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17350
HGNC: HGNC:7127
Homologene: 208
Myt1
Name: myelin transcription factor 1
Synonyms: NZF-2b, NZF-2a, Nzf2, Nztf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17932
HGNC: HGNC:7622
Homologene: 3332
Galnt9
Name: polypeptide N-acetylgalactosaminyltransferase 9
Synonyms: GalNAc-T9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231605
HGNC: HGNC:4131
Homologene: 72793
Themis
Name: thymocyte selection associated
Synonyms: E430004N04Rik, Tsepa, Gasp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 210757
Homologene: 72287
Angptl6
Name: angiopoietin-like 6
Synonyms: Arp5, AGF, Angiopoietin-related growth factor, 6330404E11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 70726
Homologene: 88931
Zfp148
Name: zinc finger protein 148
Synonyms: beta enolase repressor factor 1, BERF-1, BFCOL1, 2210405J08Rik, ZBP-89
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 22661
VEGA: 16
Homologene: 8003
Pfkp
Name: phosphofructokinase, platelet
Synonyms: PFK-C, 1200015H23Rik, 9330125N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 56421
HGNC: HGNC:8878
Homologene: 20579
Pak4
Name: p21 (RAC1) activated kinase 4
Synonyms: 5730488L07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 70584
Homologene: 4300
Ccdc88a
Name: coiled coil domain containing 88A
Synonyms: C330012F17Rik, D130005J21Rik, C130096N06Rik, GIV, A430106J12Rik, HkRP1, Girdin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 108686
Homologene: 41180
Dync1li1
Name: dynein cytoplasmic 1 light intermediate chain 1
Synonyms: LIC-1, 1110053F02Rik, Dnclic1, Dlic1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235661
VEGA: 9
Homologene: 9403
Adar
Name: adenosine deaminase, RNA-specific
Synonyms: ADAR1, mZaADAR, Adar1p150, Adar1p110
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 56417
HGNC: HGNC:225
Homologene: 9281
Pcdh17
Name: protocadherin 17
Synonyms: LOC219228, C030033F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219228
VEGA: 14
Homologene: 8700
Srcap
Name: Snf2-related CREBBP activator protein
Synonyms: F630004O05Rik, B930091H02Rik, D030022P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100043597
Homologene: 38213
Anxa9
Name: annexin A9
Synonyms: 2310069F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 71790
HGNC: HGNC:547
Homologene: 2643
Zfp648
Name: zinc finger protein 648
Synonyms: LOC207678, Gm10178
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 100503355
Homologene: 18996
Sptbn5
Name: spectrin beta, non-erythrocytic 5
Synonyms: EG640524, Spnb5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 640524
Homologene: 41150
Gm884
Name: predicted gene 884
Synonyms: LOC380730
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380730
Homologene: 134511
Tbx3
Name: T-box 3
Synonyms: D5Ertd189e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 21386
Homologene: 4371
Pth1r
Name: parathyroid hormone 1 receptor
Synonyms: PPR, PTH-related peptide receptor, PTH1R, PTH/PTHrP receptor, Pthr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 19228
HGNC: HGNC:9608
Homologene: 267
Col6a5
Name: collagen, type VI, alpha 5
Synonyms: Col6a5, Gm7455
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 665033
Homologene: 122792
Lrrk1
Name: leucine-rich repeat kinase 1
Synonyms: D130026O16Rik, C230002E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233328
Homologene: 23464
Mdga2
Name: MAM domain containing glycosylphosphatidylinositol anchor 2
Synonyms: Mdga2, 9330209L04Rik, 6720489L24Rik, Mamdc1, Adp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 320772
Homologene: 45659
Vmn2r90
Name: vomeronasal 2, receptor 90
Synonyms: EG626942
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 626942
Esm1
Name: endothelial cell-specific molecule 1
Synonyms: 0610042H23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 71690
HGNC: HGNC:3466
Homologene: 5107
Mvp
Name: major vault protein
Synonyms: VAULT1, LRP, 2310009M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 78388
HGNC: HGNC:7531
Homologene: 3752
Pcyt1a
Name: phosphate cytidylyltransferase 1, choline, alpha isoform
Synonyms: CTalpha, CTP:phosphocholine cytidylyltransferase alpha, Ctpct, Cttalpha, Cctalpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 13026
HGNC: HGNC:8754
Homologene: 3680
Bank1
Name: B cell scaffold protein with ankyrin repeats 1
Synonyms: A530094C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 242248
Homologene: 9926
Mybphl
Name: myosin binding protein H-like
Synonyms: 1110037P11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 68753
Homologene: 19221
Plin4
Name: perilipin 4
Synonyms: S3-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 57435
Homologene: 69311
Cyp26a1
Name: cytochrome P450, family 26, subfamily a, polypeptide 1
Synonyms: P450RAI, P450RA, retinoic acid hydrolase, RAH, Cyp26
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 13082
VEGA: 19
HGNC: HGNC:2603
Homologene: 37349
Ptk2b
Name: PTK2 protein tyrosine kinase 2 beta
Synonyms: CAKbeta, Raftk, calcium-dependent tyrosine kinase, related adhesion focal tyrosine kinase, cellular adhesion kinase beta, proline-rich tyrosine kinase 2, PYK2, E430023O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 19229
HGNC: HGNC:9612
Homologene: 23001
Sox5
Name: SRY (sex determining region Y)-box 5
Synonyms: A730017D01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 20678
Homologene: 21378
Mrc2
Name: mannose receptor, C type 2
Synonyms: novel lectin, Endo180, uPARAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17534
Homologene: 4408
Fam83c
Name: family with sequence similarity 83, member C
Synonyms: 5530400B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71405
Homologene: 18669
Lims2
Name: LIM and senescent cell antigen like domains 2
Synonyms: PINCH2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225341
VEGA: 18
Homologene: 41214
Grip1
Name: glutamate receptor interacting protein 1
Synonyms: 4931400F03Rik, eb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 74053
Homologene: 12938
Vmn2r96
Name: vomeronasal 2, receptor 96
Synonyms: EG433070
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 433070
Etfdh
Name: electron transferring flavoprotein, dehydrogenase
Synonyms: 0610010I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 66841
HGNC: HGNC:3483
Homologene: 3275
Kndc1
Name: kinase non-catalytic C-lobe domain (KIND) containing 1
Synonyms: VKIND, very-kind, 2410012C07Rik, B830014K08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 76484
Homologene: 45138
Best1
Name: bestrophin 1
Synonyms: best macular dystrophy, mBest1, Vmd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 24115
Homologene: 37895
Sbds
Name: SBDS ribosome maturation factor
Synonyms: 4733401P19Rik, Shwachman-Bodian-Diamond syndrome homolog (human)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 66711
Homologene: 6438
Or4c114
Name: olfactory receptor family 4 subfamily C member 114
Synonyms: GA_x6K02T2Q125-50555603-50554668, MOR233-6, Olfr1219
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258901
Homologene: 27292
Tbx5
Name: T-box 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 21388
Homologene: 160
Sccpdh
Name: saccharopine dehydrogenase (putative)
Synonyms: C330023F11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 109232
Homologene: 9334
Vav3
Name: vav 3 oncogene
Synonyms: A530094I06Rik, Idd18.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 57257
Homologene: 38143
Mfhas1
Name: malignant fibrous histiocytoma amplified sequence 1
Synonyms: 2310066G09Rik, D8Ertd91e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 52065
Homologene: 3114
Apobr
Name: apolipoprotein B receptor
Synonyms: Apob-48r, Apob48r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 171504
Homologene: 26695
Lim2
Name: lens intrinsic membrane protein 2
Synonyms: MP19, 19kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233187
Homologene: 12744
Or4c1
Name: olfactory receptor family 4 subfamily C member 1
Synonyms: GA_x6K02T2Q125-50748233-50747292, MOR235-2, Olfr1231
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258446
Homologene: 27168
Slc22a6
Name: solute carrier family 22 (organic anion transporter), member 6
Synonyms: NKT, Oat1, Orctl1, mOat1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18399
VEGA: 19
Homologene: 16813
Sall2
Name: spalt like transcription factor 2
Synonyms: Msal-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 50524
Homologene: 9269
Best2
Name: bestrophin 2
Synonyms: Vmd2l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 212989
Homologene: 41187
Or5l14
Name: olfactory receptor family 5 subfamily L member 14
Synonyms: GA_x6K02T2Q125-49446395-49445457, MOR174-1, Olfr1157
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258846
Homologene: 17402
Or55b10
Name: olfactory receptor family 55 subfamily B member 10
Synonyms: GA_x6K02T2PBJ9-5216160-5215210, MOR42-1, S50, Olfr545
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258837
Homologene: 17410
Haus4
Name: HAUS augmin-like complex, subunit 4
Synonyms: 9430093H08Rik, D14Ertd500e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219072
VEGA: 14
Homologene: 9854
Atoh7
Name: atonal bHLH transcription factor 7
Synonyms: Math5, bHLHa13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 53404
VEGA: 10
Homologene: 32338
Gvin-ps3
Name: GTPase, very large interferon inducible, pseudogene 3
Synonyms: Gm8979, Gm21884
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 668108
Gm6818
Name: predicted gene 6818
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 627975
Homologene: 80005
Or5b125-ps1
Name: olfactory receptor family 5 subfamily B member 125, pseudogene 1
Synonyms: GA_x6K02T2RE5P-3406727-3406027, MOR202-50_p, Olfr1456-ps1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 404516
Hectd2os
Name: Hectd2, opposite strand
Synonyms: 1500017E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 668215
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 78,196,746 bp
  • G to T, chromosome 1 at 154,204,406 bp
  • C to T, chromosome 1 at 171,934,113 bp
  • A to G, chromosome 1 at 179,668,410 bp
  • A to T, chromosome 2 at 87,962,709 bp
  • T to C, chromosome 2 at 89,075,068 bp
  • T to A, chromosome 2 at 89,303,277 bp
  • T to A, chromosome 2 at 120,059,416 bp
  • C to T, chromosome 2 at 155,830,234 bp
  • T to A, chromosome 2 at 181,795,739 bp
  • A to T, chromosome 3 at 79,605,803 bp
  • T to C, chromosome 3 at 86,815,093 bp
  • A to T, chromosome 3 at 89,735,940 bp
  • T to C, chromosome 3 at 95,297,356 bp
  • A to G, chromosome 3 at 108,375,178 bp
  • A to G, chromosome 3 at 109,563,218 bp
  • C to G, chromosome 3 at 136,247,676 bp
  • T to C, chromosome 4 at 6,822,983 bp
  • G to T, chromosome 4 at 104,679,553 bp
  • T to A, chromosome 4 at 118,211,022 bp
  • A to T, chromosome 5 at 104,178,062 bp
  • A to G, chromosome 5 at 110,615,509 bp
  • G to A, chromosome 5 at 119,677,570 bp
  • A to T, chromosome 5 at 119,841,899 bp
  • G to A, chromosome 5 at 130,250,975 bp
  • T to C, chromosome 6 at 143,835,316 bp
  • T to C, chromosome 6 at 148,809,958 bp
  • A to T, chromosome 7 at 28,564,249 bp
  • G to A, chromosome 7 at 38,400,702 bp
  • T to C, chromosome 7 at 43,430,681 bp
  • T to C, chromosome 7 at 66,262,487 bp
  • T to A, chromosome 7 at 102,494,452 bp
  • T to G, chromosome 7 at 106,082,378 bp
  • A to G, chromosome 7 at 126,586,847 bp
  • C to A, chromosome 7 at 126,998,328 bp
  • T to A, chromosome 7 at 127,538,544 bp
  • T to C, chromosome 7 at 139,921,779 bp
  • T to A, chromosome 8 at 35,589,175 bp
  • A to T, chromosome 8 at 85,011,203 bp
  • G to T, chromosome 9 at 20,875,302 bp
  • A to T, chromosome 9 at 54,173,333 bp
  • A to T, chromosome 9 at 71,868,967 bp
  • A to G, chromosome 9 at 105,937,172 bp
  • A to G, chromosome 9 at 110,731,624 bp
  • T to A, chromosome 9 at 110,970,093 bp
  • A to G, chromosome 9 at 111,255,658 bp
  • C to A, chromosome 9 at 114,706,098 bp
  • G to A, chromosome 10 at 28,782,651 bp
  • G to T, chromosome 10 at 63,100,496 bp
  • A to G, chromosome 10 at 81,347,452 bp
  • G to A, chromosome 10 at 120,000,554 bp
  • T to C, chromosome 11 at 29,482,241 bp
  • T to C, chromosome 11 at 73,075,677 bp
  • T to A, chromosome 11 at 103,619,860 bp
  • A to G, chromosome 11 at 103,683,929 bp
  • G to A, chromosome 11 at 105,343,702 bp
  • A to G, chromosome 12 at 66,797,633 bp
  • C to T, chromosome 13 at 6,600,635 bp
  • A to T, chromosome 13 at 113,210,060 bp
  • T to C, chromosome 14 at 52,314,478 bp
  • G to T, chromosome 14 at 54,549,799 bp
  • C to T, chromosome 14 at 66,157,069 bp
  • A to G, chromosome 14 at 84,533,520 bp
  • A to T, chromosome 15 at 101,015,691 bp
  • T to C, chromosome 16 at 32,470,224 bp
  • C to T, chromosome 16 at 33,468,135 bp
  • T to C, chromosome 16 at 89,843,282 bp
  • T to A, chromosome 17 at 17,733,694 bp
  • T to G, chromosome 17 at 18,583,008 bp
  • C to A, chromosome 17 at 56,103,762 bp
  • T to C, chromosome 17 at 84,696,697 bp
  • G to A, chromosome 18 at 31,944,499 bp
  • T to A, chromosome 19 at 8,623,652 bp
  • C to T, chromosome 19 at 9,997,135 bp
  • C to A, chromosome 19 at 13,078,862 bp
  • T to A, chromosome 19 at 36,614,338 bp
  • T to C, chromosome 19 at 37,698,477 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4693 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
041944-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.