Strain Name:
C57BL/6J-MtgxR4757Btlr/Mmmh
Stock Number:
041973-MU
Citation ID:
RRID:MMRRC_041973-MU
Other Names:
R4757 (G1), C57BL/6J-MtgxR4757Btlr
Major Collection:

Strain Information

Igf1
Name: insulin-like growth factor 1
Synonyms: Igf-1, Igf-I, C730016P09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16000
HGNC: HGNC:5464
Homologene: 515
Slc6a5
Name: solute carrier family 6 (neurotransmitter transporter, glycine), member 5
Synonyms: Glyt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 104245
Homologene: 37901
Nrxn2
Name: neurexin II
Synonyms: neurexin II beta, neurexin II alpha, 6430591O13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18190
HGNC: HGNC:8009
Homologene: 86984
Mga
Name: MAX gene associated
Synonyms: Mga, Mad5, C130042M01Rik, D030062C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 29808
Homologene: 49351
Ctnnal1
Name: catenin (cadherin associated protein), alpha-like 1
Synonyms: ACRP, Catnal1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 54366
HGNC: HGNC:2512
Homologene: 2815
Spen
Name: spen family transcription repressor
Synonyms: Mint
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56381
Homologene: 124461
Plekha7
Name: pleckstrin homology domain containing, family A member 7
Synonyms: A430081P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233765
Homologene: 52172
Apod
Name: apolipoprotein D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 11815
HGNC: HGNC:612
Homologene: 1246
Crct1
Name: cysteine-rich C-terminal 1
Synonyms: 2300002G24Rik, Nice-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 74175
Sema4b
Name: sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
Synonyms: SemC, Semac
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20352
Homologene: 8426
Timeless
Name: timeless circadian clock 1
Synonyms: tim
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 21853
Homologene: 31206
Kpnb1
Name: karyopherin (importin) beta 1
Synonyms: Impnb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16211
HGNC: HGNC:6400
Homologene: 1707
Nedd4l
Name: neural precursor cell expressed, developmentally down-regulated gene 4-like
Synonyms: 1300012C07Rik, Nedd4-2, Nedd4b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 83814
VEGA: 18
HGNC: HGNC:7728
Homologene: 86986
Akap9
Name: A kinase (PRKA) anchor protein (yotiao) 9
Synonyms: AKAP450, 5730481H23Rik, G1-448-15, repro12, mei2-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100986
HGNC: HGNC:379
Homologene: 134583
Brpf1
Name: bromodomain and PHD finger containing, 1
Synonyms: 4930540D11Rik, 4833438B11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 78783
Homologene: 31251
Trp53bp2
Name: transformation related protein 53 binding protein 2
Synonyms: ASPP2, 53BP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 209456
Homologene: 3959
Cit
Name: citron
Synonyms: CRIK-SK, citron-N, citron kinase, Cit-k, C030025P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12704
HGNC: HGNC:1985
Homologene: 21404
Bcl2l1
Name: BCL2-like 1
Synonyms: bcl-x, Bcl-XL, BclX, Bcl-Xs, Bcl(X)L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12048
HGNC: HGNC:992
Homologene: 7639
Ube3b
Name: ubiquitin protein ligase E3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 117146
Homologene: 13775
Slf2
Name: SMC5-SMC6 complex localization factor 2
Synonyms: 6030443O07Rik, Fam178a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226151
VEGA: 19
Homologene: 23077
Phox2b
Name: paired-like homeobox 2b
Synonyms: Phox2b, NBPhox, Pmx2b, GENA 269, Dilp1, Px2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18935
HGNC: HGNC:9143
Homologene: 68371
Zfp451
Name: zinc finger protein 451
Synonyms: Kiaa0576-hp, 4933435G09Rik, 4930515K21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98403
Homologene: 9188
Clec12b
Name: C-type lectin domain family 12, member B
Synonyms: 4933425B16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 71183
Homologene: 19247
Creld1
Name: cysteine-rich with EGF-like domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 171508
Homologene: 32265
Lingo1
Name: leucine rich repeat and Ig domain containing 1
Synonyms: UNQ201, LERN1, 4930471K13Rik, LINGO-1, Lrrn6a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235402
Homologene: 41891
Tut1
Name: terminal uridylyl transferase 1, U6 snRNA-specific
Synonyms: PAPD2, 2700038E08Rik, Rbm21, TUTase6, Tent1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 70044
VEGA: 19
Homologene: 69361
Deptor
Name: DEP domain containing MTOR-interacting protein
Synonyms: 4731402B04Rik, D15Ertd336e, 9130412E02Rik, D15Ertd597e, Depdc6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 97998
Homologene: 32551
Agtr1a
Name: angiotensin II receptor, type 1a
Synonyms: AT1a, Angtr-1a, Agtr-1a, AT1, Agtr1a, 1810074K20Rik, Agt1ar
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 11607
HGNC: HGNC:336
Homologene: 3556
Col4a4
Name: collagen, type IV, alpha 4
Synonyms: [a]4(IV), E130010M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12829
HGNC: HGNC:2206
Homologene: 20071
Sv2b
Name: synaptic vesicle glycoprotein 2 b
Synonyms: A830038F04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 64176
Homologene: 32236
Lsm6
Name: LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
Synonyms: 1500031N17Rik, 2410088K19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 78651
Homologene: 38271
Trpv5
Name: transient receptor potential cation channel, subfamily V, member 5
Synonyms: CaT2, ECaC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 194352
HGNC: HGNC:3145
Homologene: 10520
Zfhx4
Name: zinc finger homeodomain 4
Synonyms: Zfh-4, C130041O22Rik, Zfh4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 80892
Homologene: 23477
Nlgn1
Name: neuroligin 1
Synonyms: 6330415N05Rik, NL1, Nlg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 192167
Homologene: 56690
Msh4
Name: mutS homolog 4
Synonyms: mMsh4, 4930485C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 55993
HGNC: HGNC:7327
Homologene: 1830
Gckr
Name: glucokinase regulatory protein
Synonyms: GKRP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231103
HGNC: HGNC:4196
Homologene: 1139
Pcnx4
Name: pecanex homolog 4
Synonyms: 1810048J11Rik, Pcnxl4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 67708
VEGA: 12
Homologene: 23366
Fhod1
Name: formin homology 2 domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234686
Homologene: 136406
Cyb5d1
Name: cytochrome b5 domain containing 1
Synonyms: LOC327951
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 327951
Homologene: 15945
Npsr1
Name: neuropeptide S receptor 1
Synonyms: PGR14, VRR1, 9330128H10Rik, Gpr154
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 319239
Homologene: 45515
Stxbp5l
Name: syntaxin binding protein 5-like
Synonyms: t2md1, LLGL4, A830015P08Rik, insulin level locus 1, tomosyn-2, T2dm1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 207227
Homologene: 18173
Tgm7
Name: transglutaminase 7
Synonyms: TGz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 640543
Homologene: 14192
Ccdc150
Name: coiled-coil domain containing 150
Synonyms: 4930511H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 78016
Homologene: 15814
Mthfsd
Name: methenyltetrahydrofolate synthetase domain containing
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234814
Homologene: 11245
Tyro3
Name: TYRO3 protein tyrosine kinase 3
Synonyms: Sky, Dtk, Etk-2, Tif, Brt, Rse, Sky
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22174
Homologene: 4585
Or5b107
Name: olfactory receptor family 5 subfamily B member 107
Synonyms: GA_x6K02T2RE5P-3491834-3492772, MOR202-35, Olfr1461
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258299
HGNC: HGNC:8324
Homologene: 128112
Ppp3cc
Name: protein phosphatase 3, catalytic subunit, gamma isoform
Synonyms: PP2BA gamma, Calnc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 19057
VEGA: 14
HGNC: HGNC:9316
Homologene: 68475
Plch2
Name: phospholipase C, eta 2
Synonyms: PLCeta2, A930027K05Rik, Plcl4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 269615
Homologene: 85172
Atp1a2
Name: ATPase, Na+/K+ transporting, alpha 2 polypeptide
Synonyms: Atpa-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98660
HGNC: HGNC:800
Homologene: 47947
Gabbr2
Name: gamma-aminobutyric acid (GABA) B receptor, 2
Synonyms: Gababr2, LOC242425, Gpr51, GB2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242425
HGNC: HGNC:4507
Homologene: 55902
Herc6
Name: hect domain and RLD 6
Synonyms: 4930427L17Rik, 1700121D12Rik, CEB1, 2510038N07Rik, Herc5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 67138
Homologene: 70768
Pde7b
Name: phosphodiesterase 7B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 29863
HGNC: HGNC:8792
Homologene: 32194
Or2p2
Name: olfactory receptor family 2 subfamily P member 2
Synonyms: GA_x6K02T2QHY8-12181473-12182423, MOR256-14, Olfr1370
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 258528
Homologene: 105231
Zscan29
Name: zinc finger SCAN domains 29
Synonyms: Zfp690
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99334
Homologene: 17586
Or9g4
Name: olfactory receptor family 9 subfamily G member 4
Synonyms: GA_x6K02T2Q125-47154544-47153606, MOR213-4, Olfr1006
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258563
Homologene: 17295
4930550C14Rik
Name: RIKEN cDNA 4930550C14 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 75311
VEGA: 9
Homologene: 12595
Ankk1
Name: ankyrin repeat and kinase domain containing 1
Synonyms: 9930020N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244859
VEGA: 9
Homologene: 18258
Tlx2
Name: T cell leukemia, homeobox 2
Synonyms: Enx, Ncx1, Hox11l1, NCX, Hox11L.1, Tlx1l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 21909
HGNC: HGNC:5057
Homologene: 7575
Or52d3
Name: olfactory receptor family 52 subfamily D member 3
Synonyms: GA_x6K02T2PBJ9-7206970-7207923, MOR33-1, Olfr653
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 57250
Homologene: 115518
Mrgpra4
Name: MAS-related GPR, member A4
Synonyms: MrgA4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 235854
Homologene: 131159
Plekha8
Name: pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
Synonyms: FAPP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 231999
Homologene: 32284
Car13
Name: carbonic anhydrase 13
Synonyms: 2310075C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 71934
Homologene: 75207
Mks1
Name: MKS transition zone complex subunit 1
Synonyms: B8d3, avc6, Meckel syndrome, type 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380718
HGNC: HGNC:7121
Homologene: 9833
Abcb1a
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 1A
Synonyms: mdr-3, Mdr1a, P-gp, P-glycoprotein, Pgy-3, Pgy3, multiple drug resistant 1a, MDR3, Pgp, Evi32
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18671
HGNC: HGNC:40
Homologene: 55496
Slx1b
Name: SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
Synonyms: 4833422P03Rik, 2410170E21Rik, 1110030E23Rik, Giyd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 75764
Homologene: 11434
Or5b113
Name: olfactory receptor family 5 subfamily B member 113
Synonyms: GA_x6K02T2RE5P-3695694-3696620, MOR202-15, Olfr1467
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258686
HGNC: HGNC:8324
Homologene: 133888
Dnajb12
Name: DnaJ heat shock protein family (Hsp40) member B12
Synonyms: mDj10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 56709
Homologene: 9749
Fem1al
Name: fem-1 homolog A like
Synonyms: 4931440F15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216622
Foxf2
Name: forkhead box F2
Synonyms: FREAC2, Fkh20, LUN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 14238
HGNC: HGNC:3810
Homologene: 1115
Vmn2r69
Name: vomeronasal 2, receptor 69
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 330581
Homologene: 115466
Trmt10a
Name: tRNA methyltransferase 10A
Synonyms: 3110023L08Rik, Rg9mtd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 108943
Homologene: 6886
Cibar2
Name: CBY1 interacting BAR domain containing 2
Synonyms: 1700120B06Rik, Fam92b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 436062
Homologene: 78513
Acsm4
Name: acyl-CoA synthetase medium-chain family member 4
Synonyms: O-MACS, OMACS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233801
Homologene: 72281
Gm10354
Name: predicted gene 10354
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100503549
Homologene: 69402
Slc25a23
Name: solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
Synonyms: 2310067G05Rik, SCaMC-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 66972
Homologene: 11467
Pou2af1
Name: POU domain, class 2, associating factor 1
Synonyms: OBF.1, BOB.1, OBF-1, Bob1, OCA-B, OCAB, Bob-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 18985
VEGA: 9
HGNC: HGNC:9211
Homologene: 4543
Duoxa2
Name: dual oxidase maturation factor 2
Synonyms: 9030623N16Rik, Nip2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66811
Homologene: 57037
Myl12a
Name: myosin, light chain 12A, regulatory, non-sarcomeric
Synonyms: brain specific myosin regulatory light chain, NMDA receptor-interacting protein, 2900073G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 67268
Homologene: 68515
Igkv6-14
Name: immunoglobulin kappa variable 6-14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 667881
Ighv8-13
Name: immunoglobulin heavy variable 8-13
Synonyms: Gm16810
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 100775172
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 33,765,858 bp
  • A to T, chromosome 1 at 54,278,715 bp
  • A to G, chromosome 1 at 82,528,466 bp
  • A to T, chromosome 1 at 172,284,451 bp
  • A to T, chromosome 1 at 182,458,774 bp
  • A to G, chromosome 2 at 85,674,320 bp
  • A to G, chromosome 2 at 119,810,938 bp
  • A to G, chromosome 2 at 119,903,639 bp
  • A to T, chromosome 2 at 121,096,389 bp
  • A to T, chromosome 2 at 121,160,911 bp
  • G to T, chromosome 2 at 122,300,591 bp
  • T to A, chromosome 2 at 152,782,258 bp
  • T to A, chromosome 3 at 5,400,062 bp
  • T to C, chromosome 3 at 14,661,555 bp
  • T to A, chromosome 3 at 25,436,168 bp
  • C to T, chromosome 3 at 25,436,343 bp
  • G to A, chromosome 3 at 93,014,786 bp
  • A to G, chromosome 3 at 138,149,465 bp
  • T to A, chromosome 3 at 153,879,387 bp
  • T to C, chromosome 4 at 46,875,675 bp
  • T to A, chromosome 4 at 56,847,980 bp
  • T to A, chromosome 4 at 141,473,079 bp
  • T to A, chromosome 4 at 154,996,233 bp
  • T to C, chromosome 5 at 4,008,382 bp
  • T to A, chromosome 5 at 8,737,632 bp
  • T to A, chromosome 5 at 14,976,208 bp
  • G to T, chromosome 5 at 31,307,384 bp
  • A to T, chromosome 5 at 67,098,854 bp
  • C to T, chromosome 5 at 114,389,097 bp
  • T to A, chromosome 5 at 115,997,549 bp
  • T to A, chromosome 6 at 41,653,214 bp
  • A to G, chromosome 6 at 54,622,228 bp
  • G to A, chromosome 6 at 57,600,060 bp
  • A to T, chromosome 6 at 70,435,442 bp
  • A to G, chromosome 6 at 83,069,919 bp
  • A to T, chromosome 6 at 113,315,111 bp
  • A to G, chromosome 6 at 113,492,247 bp
  • A to G, chromosome 6 at 129,380,692 bp
  • T to A, chromosome 7 at 47,980,938 bp
  • T to G, chromosome 7 at 49,959,282 bp
  • T to C, chromosome 7 at 75,124,170 bp
  • T to C, chromosome 7 at 80,216,829 bp
  • T to A, chromosome 7 at 85,412,367 bp
  • T to C, chromosome 7 at 104,580,197 bp
  • A to G, chromosome 7 at 116,157,998 bp
  • T to C, chromosome 7 at 119,698,677 bp
  • A to G, chromosome 7 at 126,692,529 bp
  • T to C, chromosome 8 at 78,813,082 bp
  • C to A, chromosome 8 at 105,347,811 bp
  • T to C, chromosome 8 at 120,171,924 bp
  • C to T, chromosome 8 at 121,098,998 bp
  • T to C, chromosome 9 at 24,134,768 bp
  • T to A, chromosome 9 at 49,415,930 bp
  • T to A, chromosome 9 at 51,233,139 bp
  • A to T, chromosome 9 at 53,425,530 bp
  • A to G, chromosome 9 at 56,619,925 bp
  • T to C, chromosome 10 at 20,547,942 bp
  • A to G, chromosome 10 at 59,892,770 bp
  • A to T, chromosome 10 at 87,915,425 bp
  • C to T, chromosome 10 at 128,240,476 bp
  • A to T, chromosome 11 at 29,825,454 bp
  • T to C, chromosome 11 at 69,394,988 bp
  • A to G, chromosome 11 at 87,863,024 bp
  • C to T, chromosome 11 at 97,177,334 bp
  • T to C, chromosome 12 at 72,556,293 bp
  • T to A, chromosome 12 at 115,765,648 bp
  • T to C, chromosome 13 at 21,072,545 bp
  • C to A, chromosome 13 at 30,381,859 bp
  • C to T, chromosome 13 at 31,626,189 bp
  • T to A, chromosome 14 at 70,218,186 bp
  • A to T, chromosome 15 at 55,212,278 bp
  • T to A, chromosome 16 at 31,303,462 bp
  • T to C, chromosome 16 at 37,188,634 bp
  • A to G, chromosome 17 at 57,056,688 bp
  • A to T, chromosome 17 at 70,996,803 bp
  • A to G, chromosome 18 at 65,165,605 bp
  • A to G, chromosome 19 at 6,509,821 bp
  • G to T, chromosome 19 at 8,959,308 bp
  • A to C, chromosome 19 at 13,165,913 bp
  • G to T, chromosome 19 at 13,365,446 bp
  • A to G, chromosome 19 at 44,935,058 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4757 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
041973-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.