Strain Name:
C57BL/6J-MtgxR4715Btlr/Mmmh
Stock Number:
041982-MU
Citation ID:
RRID:MMRRC_041982-MU
Other Names:
R4715 (G1), C57BL/6J-MtgxR4715Btlr
Major Collection:

Strain Information

Casq2
Name: calsequestrin 2
Synonyms: cCSQ, ESTM52, Csq2, cardiac calsequestrin
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12373
HGNC: HGNC:1513
Homologene: 20330
Prkd3
Name: protein kinase D3
Synonyms: Prkcn, 5730497N19Rik, 4930557O20Rik, PKD3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 75292
HGNC: HGNC:9408
Homologene: 2055
Atp1a1
Name: ATPase, Na+/K+ transporting, alpha 1 polypeptide
Synonyms: Atpa-1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11928
HGNC: HGNC:799
Homologene: 564
Atf2
Name: activating transcription factor 2
Synonyms: D130078H02Rik, ATF-2, Creb2, mXBP, CRE-BP
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11909
HGNC: HGNC:784
Homologene: 31061
Cfdp1
Name: craniofacial development protein 1
Synonyms: Bucentaur, cp27, Bcnt
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 23837
HGNC: HGNC:1873
Homologene: 4611
Pdzd2
Name: PDZ domain containing 2
Synonyms: A930022H17Rik, 4930537L06Rik, LOC223364, Pdzk3, Gm21706
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 68070
Homologene: 23393
Htr1b
Name: 5-hydroxytryptamine (serotonin) receptor 1B
Synonyms: 5-HT1B receptor, 5-HT1B receptor, 5HT1B receptor
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 15551
HGNC: HGNC:5287
Homologene: 669
E2f3
Name: E2F transcription factor 3
Synonyms: E2f3a, E2F3b
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 13557
HGNC: HGNC:3115
Homologene: 74413
Ltn1
Name: listerin E3 ubiquitin protein ligase 1
Synonyms: Listerin, 4930528H02Rik, Zfp294, Rnf160
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 78913
VEGA: 16
Homologene: 32272
Map4k4
Name: mitogen-activated protein kinase kinase kinase kinase 4
Synonyms: Nik, 9430080K19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 26921
HGNC: HGNC:6866
Homologene: 7442
Nop58
Name: NOP58 ribonucleoprotein
Synonyms: Nol5, MSSP, SIK similar protein
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 55989
Homologene: 7024
Mrps27
Name: mitochondrial ribosomal protein S27
Synonyms: 2610028H14Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218506
VEGA: 13
Homologene: 41006
Gtf2h1
Name: general transcription factor II H, polypeptide 1
Synonyms: 62kDa, p62
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14884
HGNC: HGNC:4655
Homologene: 3885
Arap2
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
Synonyms: Centd1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 212285
Homologene: 9064
Bptf
Name: bromodomain PHD finger transcription factor
Synonyms: 9430093H17Rik, Falz
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 207165
HGNC: HGNC:3581
Homologene: 114397
F2rl1
Name: F2R like trypsin receptor 1
Synonyms: coagulation factor II (thrombin) receptor-like 1, Protease-activated receptor-2, Par2, proteinase-activated receptor-2, PAR-2, Gpcr11
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 14063
VEGA: 13
HGNC: HGNC:3538
Homologene: 21087
Rif1
Name: replication timing regulatory factor 1
Synonyms: 6530403D07Rik, 5730435J01Rik, D2Ertd145e
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 51869
Homologene: 41231
Ralgapa1
Name: Ral GTPase activating protein, alpha subunit 1
Synonyms: 4930400K19Rik, Garnl1, Tulip1, 2310003F20Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 56784
VEGA: 12
Homologene: 84805
Abcc5
Name: ATP-binding cassette, sub-family C member 5
Synonyms: Mrp5, Abcc5b, 2900011L11Rik, Abcc5a
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 27416
HGNC: HGNC:56
Homologene: 21164
Dmxl2
Name: Dmx-like 2
Synonyms: E130119P06Rik, 6430411K14Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235380
HGNC: HGNC:2938
Homologene: 41022
Pum2
Name: pumilio RNA-binding family member 2
Synonyms: 5730503J23Rik, Pumm2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 80913
Homologene: 69183
Top3a
Name: topoisomerase (DNA) III alpha
Synonyms: Top IIIa
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 21975
Homologene: 3394
Copg1
Name: coatomer protein complex, subunit gamma 1
Synonyms: D6Ertd71e, D6Wsu16e, Copg
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 54161
HGNC: HGNC:2236
Homologene: 56745
Usp8
Name: ubiquitin specific peptidase 8
Synonyms: Ubpy
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 84092
Homologene: 3782
Dock2
Name: dedicator of cyto-kinesis 2
Synonyms: CED-5, MBC, Hch
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 94176
HGNC: HGNC:2988
Homologene: 37984
Elf3
Name: E74-like factor 3
Synonyms: ESE-1, jen, ESX
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13710
HGNC: HGNC:3318
Homologene: 3265
Ptprd
Name: protein tyrosine phosphatase receptor type D
Synonyms: B230219D21Rik, 1110002J03Rik, 3000002J10Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 19266
HGNC: HGNC:9668
Siglec1
Name: sialic acid binding Ig-like lectin 1, sialoadhesin
Synonyms: Siglec-1, CD169, Sn
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20612
Homologene: 124458
Dnah14
Name: dynein, axonemal, heavy chain 14
Synonyms: Gm980, Dnahc14, A230079K17Rik, LOC381311
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240960
HGNC: HGNC:2945
Homologene: 90078
Cyp4a10
Name: cytochrome P450, family 4, subfamily a, polypeptide 10
Synonyms: D4Rp1, Msp-3, Cyp4a, RP1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13117
HGNC: HGNC:2642
Homologene: 128044
Kcnk7
Name: potassium channel, subfamily K, member 7
Synonyms: 2310014G03Rik, Kcnk8, Knot, Mlk3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 16530
HGNC: HGNC:6282
Homologene: 43131
Wnk2
Name: WNK lysine deficient protein kinase 2
Synonyms: X83337, 1810073P09Rik, ESTM15
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 75607
Homologene: 19155
Synpr
Name: synaptoporin
Synonyms: 1500003F20Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 72003
Homologene: 11407
Treh
Name: trehalase (brush-border membrane glycoprotein)
Synonyms: 2210412M19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 58866
Homologene: 5198
Klf17
Name: Kruppel-like transcription factor 17
Synonyms: D4Ertd561e, Zfp393, 7420700M05Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 75753
Homologene: 12621
Atosa
Name: atos homolog A
Synonyms: C130047D21Rik, Fam214a, 6330415I01Rik, BC031353
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235493
VEGA: 9
Homologene: 35065
Cgn
Name: cingulin
Synonyms: 6330408J11Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70737
Homologene: 41394
Gm5546
Name: predicted gene 5546
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 433634
Cdh4
Name: cadherin 4
Synonyms: R-cadherin, R-Cadh, Rcad
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12561
HGNC: HGNC:1763
Homologene: 48044
Moxd2
Name: monooxygenase, DBH-like 2
Synonyms: Dbhl1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 194357
Homologene: 77226
Htatip2
Name: HIV-1 Tat interactive protein 2
Synonyms: TIP30
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 53415
Homologene: 4676
Shc2
Name: SHC (Src homology 2 domain containing) transforming protein 2
Synonyms: ShcB, Sli
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216148
Homologene: 19127
Dthd1
Name: death domain containing 1
Synonyms: Gm17384
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100322896
Homologene: 123510
Rhoc
Name: ras homolog family member C
Synonyms: Arh9, Arhc
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11853
HGNC: HGNC:669
Homologene: 90945
Tmc3
Name: transmembrane channel-like gene family 3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233424
Homologene: 45588
Clpx
Name: caseinolytic mitochondrial matrix peptidase chaperone subunit
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270166
HGNC: HGNC:2088
Homologene: 4851
Gucy1b2
Name: guanylate cyclase 1, soluble, beta 2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239134
HGNC: HGNC:4686
Homologene: 136630
Abcc2
Name: ATP-binding cassette, sub-family member 2
Synonyms: Mrp2, multidrug resistance protein 2, Cmoat
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 12780
HGNC: HGNC:53
Homologene: 68052
Ifi205
Name: interferon activated gene 205
Synonyms: D3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226695
Homologene: 115929
Tiam2
Name: T cell lymphoma invasion and metastasis 2
Synonyms: STEF, 3000002F19Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 24001
VEGA: 17
Homologene: 40796
Tmem38b
Name: transmembrane protein 38B
Synonyms: 1600017F22Rik, D4Ertd89e, TRIC-B
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 52076
Homologene: 10010
Mark1
Name: MAP/microtubule affinity regulating kinase 1
Synonyms: Emk3, B930025N23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226778
HGNC: HGNC:6896
Homologene: 49552
Evi5l
Name: ecotropic viral integration site 5 like
Synonyms: B130050I23Rik, 2310039H16Rik, 1700084G18Rik, 3110007G05Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 213027
Homologene: 134635
Or2n1d
Name: olfactory receptor family 2 subfamily N member 1D
Synonyms: MOR256-7, Olfr136, GA_x6K02T2PSCP-2779375-2780313
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 258803
Homologene: 119758
Yju2b
Name: YJU2 splicing factor homolog B
Synonyms: 4930527D15Rik, Ccdc130
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 67736
Homologene: 12183
Dip2a
Name: disco interacting protein 2 homolog A
Synonyms: Dip2, 4931420H10Rik, Kiaa0184-hp
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 64451
Homologene: 41012
Or13p5
Name: olfactory receptor family 13 subfamily P member 5
Synonyms: GA_x6K02T2QD9B-18815145-18814198, Olfr1339, MOR258-2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 258851
Homologene: 27280
Tdrd9
Name: tudor domain containing 9
Synonyms: 4930441E05Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 74691
Homologene: 14311
Ammecr1l
Name: AMME chromosomal region gene 1-like
Synonyms: 5430429D03Rik, E230022H04Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225339
VEGA: 18
Homologene: 69488
Ubash3b
Name: ubiquitin associated and SH3 domain containing, B
Synonyms: 2810457I06Rik, Sts-1, TULA-2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 72828
Homologene: 13152
Or7g19
Name: olfactory receptor family 7 subfamily G member 19
Synonyms: Olfr832, MOR153-1, GA_x6K02T2PVTD-12687800-12688738
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258075
HGNC: HGNC:8467
Homologene: 128143
Alox8
Name: arachidonate 8-lipoxygenase
Synonyms: 8-LOX, 8S-lipoxygenase, 8S-LOX, Alox15b
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11688
HGNC: HGNC:434
Homologene: 886
Or2t46
Name: olfactory receptor family 2 subfamily T member 46
Synonyms: MOR275-5, MOR275-11_p, GA_x6K02T2NKPP-844642-843680, Olfr325
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258261
Homologene: 133015
Med11
Name: mediator complex subunit 11
Synonyms: 1110030J09Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 66172
Homologene: 32630
Fpr-rs7
Name: formyl peptide receptor, related sequence 7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 321021
HGNC: HGNC:3827
Cdk5rap1
Name: CDK5 regulatory subunit associated protein 1
Synonyms: 2310066P17Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66971
Homologene: 9502
Podnl1
Name: podocan-like 1
Synonyms: 5832418A03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244550
Homologene: 41590
Slc25a18
Name: solute carrier family 25 (mitochondrial carrier), member 18
Synonyms: 1500015I14Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 71803
Homologene: 57151
Or4k42
Name: olfactory receptor family 4 subfamily K member 42
Synonyms: Olfr1290, MOR248-9, GA_x6K02T2Q125-72541649-72540711
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 257662
Homologene: 74248
B4galt2
Name: UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 53418
HGNC: HGNC:925
Homologene: 2804
Cdc42ep3
Name: CDC42 effector protein 3
Synonyms: Borg2, 3200001F04Rik, UB1, Cep3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 260409
VEGA: 17
Homologene: 4708
Or7g26
Name: olfactory receptor family 7 subfamily G member 26
Synonyms: GA_x6K02T2PVTD-13056760-13057689, MOR153-3, Olfr844
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 100503048
HGNC: HGNC:8466
Tmem37
Name: transmembrane protein 37
Synonyms: Pr1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 170706
Homologene: 10447
Rspo2
Name: R-spondin 2
Synonyms: ftls, 2610028F08Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239405
VEGA: 15
Homologene: 18235
Smpd5
Name: sphingomyelin phosphodiesterase 5
Synonyms: Gm10345
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 100503915
Homologene: 132205
Gm8267
Name: predicted gene 8267
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 666744
Homologene: 115686
Sco1
Name: SCO1 cytochrome c oxidase assembly protein
Synonyms: 2610001C07Rik, D11Bwg1310e
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 52892
Homologene: 3374
Heatr2
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Tmem200c
Name: transmembrane protein 200C
Synonyms: Gm6338
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 622645
VEGA: 17
Homologene: 78765
Mrpl33
Name: mitochondrial ribosomal protein L33
Synonyms: 0610009M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 66845
Homologene: 81733
Igkv18-36
Name: immunoglobulin kappa chain variable 18-36
Synonyms: Gm16689
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 620088
Gm10698
Name: predicted gene 10698
Synonyms: Gm19904
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
2310058D17Rik
Name: RIKEN cDNA 2310058D17 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Ggact
Name: gamma-glutamylamine cyclotransferase
Synonyms: A2ld1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 223267
Homologene: 15522
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 40,019,564 bp
  • T to C, chromosome 1 at 59,696,026 bp
  • A to T, chromosome 1 at 120,068,205 bp
  • C to T, chromosome 1 at 135,257,752 bp
  • T to C, chromosome 1 at 174,028,321 bp
  • A to G, chromosome 1 at 181,757,223 bp
  • A to G, chromosome 1 at 184,912,132 bp
  • T to C, chromosome 2 at 52,073,139 bp
  • C to A, chromosome 2 at 73,823,300 bp
  • A to C, chromosome 2 at 111,489,744 bp
  • T to A, chromosome 2 at 126,729,222 bp
  • T to C, chromosome 2 at 131,074,436 bp
  • C to A, chromosome 2 at 154,361,835 bp
  • A to T, chromosome 2 at 179,780,467 bp
  • C to A, chromosome 3 at 94,779,438 bp
  • T to C, chromosome 3 at 101,591,806 bp
  • T to C, chromosome 3 at 102,110,244 bp
  • T to C, chromosome 3 at 104,366,508 bp
  • T to C, chromosome 3 at 104,794,039 bp
  • C to A, chromosome 4 at 53,826,076 bp
  • T to C, chromosome 4 at 76,107,333 bp
  • A to T, chromosome 4 at 115,525,338 bp
  • T to C, chromosome 4 at 117,760,536 bp
  • T to C, chromosome 4 at 117,877,179 bp
  • T to C, chromosome 4 at 118,734,655 bp
  • A to G, chromosome 5 at 31,616,358 bp
  • G to T, chromosome 5 at 62,749,094 bp
  • A to C, chromosome 5 at 62,888,187 bp
  • A to T, chromosome 5 at 139,178,000 bp
  • A to G, chromosome 6 at 40,887,247 bp
  • C to T, chromosome 6 at 69,992,591 bp
  • T to A, chromosome 6 at 87,912,286 bp
  • T to C, chromosome 6 at 120,786,090 bp
  • A to G, chromosome 7 at 46,815,412 bp
  • T to C, chromosome 7 at 49,770,844 bp
  • G to A, chromosome 7 at 83,622,396 bp
  • G to T, chromosome 8 at 4,203,552 bp
  • C to A, chromosome 8 at 84,126,061 bp
  • A to G, chromosome 8 at 84,263,874 bp
  • G to A, chromosome 8 at 111,830,891 bp
  • A to G, chromosome 9 at 18,945,446 bp
  • C to A, chromosome 9 at 19,319,147 bp
  • A to T, chromosome 9 at 33,728,488 bp
  • T to C, chromosome 9 at 41,016,600 bp
  • T to C, chromosome 9 at 44,683,318 bp
  • A to C, chromosome 9 at 54,446,405 bp
  • A to C, chromosome 9 at 65,312,114 bp
  • T to A, chromosome 9 at 75,012,968 bp
  • T to C, chromosome 9 at 81,631,510 bp
  • T to C, chromosome 10 at 76,296,406 bp
  • T to C, chromosome 10 at 79,622,379 bp
  • T to C, chromosome 11 at 34,294,118 bp
  • A to G, chromosome 11 at 58,581,429 bp
  • A to C, chromosome 11 at 58,968,450 bp
  • T to A, chromosome 11 at 60,742,997 bp
  • A to G, chromosome 11 at 67,056,599 bp
  • A to T, chromosome 11 at 69,186,549 bp
  • T to C, chromosome 11 at 70,453,196 bp
  • G to T, chromosome 11 at 107,047,181 bp
  • T to A, chromosome 12 at 8,747,272 bp
  • T to A, chromosome 12 at 55,693,458 bp
  • T to G, chromosome 12 at 112,041,689 bp
  • A to C, chromosome 13 at 29,911,275 bp
  • T to A, chromosome 13 at 49,147,232 bp
  • A to T, chromosome 13 at 95,513,267 bp
  • A to G, chromosome 13 at 99,414,815 bp
  • CT to C, chromosome 14 at 13,285,198 bp
  • A to G, chromosome 14 at 44,717,835 bp
  • A to G, chromosome 14 at 62,423,017 bp
  • A to T, chromosome 14 at 122,891,635 bp
  • G to T, chromosome 15 at 12,419,516 bp
  • A to T, chromosome 15 at 43,075,904 bp
  • A to T, chromosome 15 at 76,295,693 bp
  • G to T, chromosome 16 at 20,398,876 bp
  • A to G, chromosome 16 at 87,418,494 bp
  • T to A, chromosome 17 at 3,454,168 bp
  • C to T, chromosome 17 at 20,113,428 bp
  • A to C, chromosome 17 at 38,335,840 bp
  • A to T, chromosome 17 at 68,840,470 bp
  • G to T, chromosome 17 at 78,951,937 bp
  • G to A, chromosome 17 at 79,335,458 bp
  • C to T, chromosome 18 at 31,774,653 bp
  • T to C, chromosome 19 at 5,706,253 bp
  • A to C, chromosome 19 at 43,816,882 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4715 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
041982-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.