Strain Name:
C57BL/6J-MtgxR4775Btlr/Mmmh
Stock Number:
041991-MU
Citation ID:
RRID:MMRRC_041991-MU
Other Names:
R4775 (G1), C57BL/6J-MtgxR4775Btlr
Major Collection:

Gene Information

Gnai2
Name: guanine nucleotide binding protein (G protein), alpha inhibiting 2
Synonyms: Galphai2, Gia, Gnai-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 14678
HGNC: HGNC:4385
Homologene: 55539
Cwf19l2
Name: CWF19-like 2, cell cycle control (S. pombe)
Synonyms: 3230401L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244672
Homologene: 12366
Foxj2
Name: forkhead box J2
Synonyms: Fhx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 60611
Homologene: 10187
Slc2a3
Name: solute carrier family 2 (facilitated glucose transporter), member 3
Synonyms: Glut-3, Glut3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 20527
Homologene: 74302
Stk11ip
Name: serine/threonine kinase 11 interacting protein
Synonyms: LKB1IP, LIP1, 1200014D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 71728
Homologene: 12406
Ndc80
Name: NDC80 kinetochore complex component
Synonyms: Kntc2, 2610020P18Rik, HEC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 67052
VEGA: 17
Homologene: 38141
Tars2
Name: threonyl-tRNA synthetase 2, mitochondrial (putative)
Synonyms: Tarsl1, 2610024N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 71807
Homologene: 23520
Prr12
Name: proline rich 12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233210
Homologene: 18957
Atp9b
Name: ATPase, class II, type 9B
Synonyms: IIb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 50771
VEGA: 18
Homologene: 21915
Nfrkb
Name: nuclear factor related to kappa B binding protein
Synonyms: A530090G11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235134
HGNC: HGNC:7802
Homologene: 4492
Afg3l2
Name: AFG3-like AAA ATPase 2
Synonyms: 2310036I02Rik, Emv66, par
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 69597
VEGA: 18
HGNC: HGNC:315
Homologene: 4947
Trim66
Name: tripartite motif-containing 66
Synonyms: D7H11orf29, Tif1d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 330627
Homologene: 28044
Trio
Name: triple functional domain (PTPRF interacting)
Synonyms: Solo, 6720464I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223435
VEGA: 15
Homologene: 20847
Wipf2
Name: WAS/WASL interacting protein family, member 2
Synonyms: 5730509C05Rik, 1110014J05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 68524
Homologene: 15777
Myt1
Name: myelin transcription factor 1
Synonyms: NZF-2a, Nztf2, Nzf2, NZF-2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17932
HGNC: HGNC:7622
Homologene: 3332
Grm7
Name: glutamate receptor, metabotropic 7
Synonyms: Tg(SMN2)89Ahmb, SMN2, 6330570A01Rik, mGlu7a receptor, E130018M02Rik, Gpr1g, mGluR7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 108073
HGNC: HGNC:4599
Homologene: 20233
Rph3a
Name: rabphilin 3A
Synonyms: Doc2 family, 2900002P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 19894
Homologene: 7921
Acaca
Name: acetyl-Coenzyme A carboxylase alpha
Synonyms: acetyl-CoA carboxylase, LOC327983, Acac, A530025K05Rik, Acc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 107476
HGNC: HGNC:84
Homologene: 31015
Dsg4
Name: desmoglein 4
Synonyms: CDHF13, lah
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 16769
Homologene: 65341
Ppp4r3a
Name: protein phosphatase 4 regulatory subunit 3A
Synonyms: Smek1, 1110034C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 68734
VEGA: 12
Homologene: 69510
Gm94
Name: predicted gene 94
Synonyms: LOC225443
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225443
VEGA: 18
Homologene: 19192
Mpzl3
Name: myelin protein zero-like 3
Synonyms: ruf, A530065I17Rik, rc, 5430427F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 319742
Homologene: 18867
F11r
Name: F11 receptor
Synonyms: Jcam1, BV11 antigen, ESTM33, JAM-1, JAM-A, Ly106
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 16456
Homologene: 14255
Dapk1
Name: death associated protein kinase 1
Synonyms: 2810425C21Rik, 2310039H24Rik, DAP-Kinase, D13Ucla1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 69635
VEGA: 13
HGNC: HGNC:2674
Homologene: 3626
Gle1
Name: GLE1 RNA export mediator (yeast)
Synonyms: 4933405K21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 74412
HGNC: HGNC:4315
Homologene: 20379
Qser1
Name: glutamine and serine rich 1
Synonyms: 4732486I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 99003
Homologene: 11710
Svil
Name: supervillin
Synonyms: B430302E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225115
Homologene: 25090
Pask
Name: PAS domain containing serine/threonine kinase
Synonyms: Paskin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 269224
Homologene: 9038
Rab40c
Name: Rab40C, member RAS oncogene family
Synonyms: RAR3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224624
Homologene: 10907
Tpcn2
Name: two pore segment channel 2
Synonyms: D830047E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233979
Homologene: 16375
Eml5
Name: echinoderm microtubule associated protein like 5
Synonyms: C130068M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 319670
VEGA: 12
Homologene: 26807
Ccdc174
Name: coiled-coil domain containing 174
Synonyms: C130022K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232236
Homologene: 9523
Grin1
Name: glutamate receptor, ionotropic, NMDA1 (zeta 1)
Synonyms: M100174, NR1, GluRzeta1, Nmdar, Rgsc174, NMDAR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 14810
HGNC: HGNC:4584
Homologene: 7187
Marveld2
Name: MARVEL (membrane-associating) domain containing 2
Synonyms: Tric-c, Tric-a, Tricellulin, Tric-b, Tric, Mrvldc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218518
VEGA: 13
Homologene: 27037
Tns2
Name: tensin 2
Synonyms: nep, Tenc1, nph
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 209039
VEGA: 15
Homologene: 37077
BC067074
Name: cDNA sequence BC067074
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 408066
Mylk3
Name: myosin light chain kinase 3
Synonyms: D830007F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 213435
Homologene: 35278
C5ar2
Name: complement component 5a receptor 2
Synonyms: C5L2, E030029A11Rik, Gpr77
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 319430
HGNC: HGNC:4527
Homologene: 49549
Taok2
Name: TAO kinase 2
Synonyms: TAO2, TAO1, 1110033K02Rik, PSK1, MAP3K17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 381921
Homologene: 74531
Pglyrp3
Name: peptidoglycan recognition protein 3
Synonyms: LOC242100
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 242100
Homologene: 71559
Dis3l
Name: DIS3 like exosome 3'-5' exoribonuclease
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 213550
Homologene: 15797
Stkld1
Name: serine/threonine kinase-like domain containing 1
Synonyms: LOC279029, Gm711
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 279029
Homologene: 19586
Gtf2ird2
Name: GTF2I repeat domain containing 2
Synonyms: 1700012P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 114674
Homologene: 24941
Olfr389
Name: olfactory receptor 389
Synonyms: MOR135-6, GA_x6K02T2P1NL-3932085-3931147
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 259011
Homologene: 85925
Mppe1
Name: metallophosphoesterase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225651
VEGA: 18
Homologene: 41512
Fanca
Name: Fanconi anemia, complementation group A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 14087
HGNC: HGNC:3582
Homologene: 108
Adamts1
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
Synonyms: METH-1, METH1, ADAM-TS1, ADAMTS-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 11504
HGNC: HGNC:217
Homologene: 21381
Engase
Name: endo-beta-N-acetylglucosaminidase
Synonyms: D230014K01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217364
Homologene: 13666
Gpaa1
Name: GPI anchor attachment protein 1
Synonyms: mGAA1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 14731
HGNC: HGNC:4446
Homologene: 37852
Adam7
Name: a disintegrin and metallopeptidase domain 7
Synonyms: EAP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 11500
HGNC: HGNC:214
Homologene: 2830
Ankzf1
Name: ankyrin repeat and zinc finger domain containing 1
Synonyms: D1Ertd161e, 1300008P06Rik, 2810025E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 52231
Homologene: 41225
Adgrf1
Name: adhesion G protein-coupled receptor F1
Synonyms: Gpr110, 5031409J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 77596
Homologene: 124643
Zfp286
Name: zinc finger protein 286
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 192651
Homologene: 56892
Mpl
Name: myeloproliferative leukemia virus oncogene
Synonyms: c-mpl-I, CD110, thrombopoietin receptor, c-mpl, hlb219, c-mpl-II, TPO-R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 17480
HGNC: HGNC:7217
Homologene: 7845
Trappc3l
Name: trafficking protein particle complex 3 like
Synonyms: ENSMUSG00000071340, Bet3l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 692132
VEGA: 10
Homologene: 82663
Ptdss1
Name: phosphatidylserine synthase 1
Synonyms: PtdSer Synthase-1, PSS-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 19210
VEGA: 13
HGNC: HGNC:9587
Homologene: 7494
Nlrp4e
Name: NLR family, pyrin domain containing 4E
Synonyms: Nalp4e, 4930406H16Rik, Nalp-epsilon
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 446099
Homologene: 75315
Skint4
Name: selection and upkeep of intraepithelial T cells 4
Synonyms: 9530098N22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 320640
Smyd4
Name: SET and MYND domain containing 4
Synonyms: G430029E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 319822
Homologene: 35098
Dvl1
Name: dishevelled segment polarity protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 13542
HGNC: HGNC:3084
Homologene: 20926
Col25a1
Name: collagen, type XXV, alpha 1
Synonyms: 2700062B08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 77018
Homologene: 57111
Nelfcd
Name: negative elongation factor complex member C/D, Th1l
Synonyms: 2410003I03Rik, trihydrophobin 1, Th1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 57314
Homologene: 9496
Lipo1
Name: lipase, member O1
Synonyms: Gm5097
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 329055
Homologene: 86428
Nt5c1b
Name: 5'-nucleotidase, cytosolic IB
Synonyms: CN-IB, 4921514H13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 70881
Homologene: 12370
Lonrf2
Name: LON peptidase N-terminal domain and ring finger 2
Synonyms: 2900060P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 381338
Homologene: 18871
Nipa2
Name: non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)
Synonyms: 3830408P04Rik, 2600017P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 93790
Homologene: 11368
Nr2e3
Name: nuclear receptor subfamily 2, group E, member 3
Synonyms: photoreceptor-specific nuclear receptor, RNR, Pnr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 23958
HGNC: HGNC:7974
Homologene: 84397
Olfr61
Name: olfactory receptor 61
Synonyms: GA_x6K02T2PBJ9-42783826-42784758, MOR253-1, IH7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18362
Homologene: 79374
Cox6b2
Name: cytochrome c oxidase subunit 6B2
Synonyms: 1700067P11Rik, COXVIB2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 333182
Homologene: 16948
Cidec
Name: cell death-inducing DFFA-like effector c
Synonyms: Fsp27, CIDE-3, CIDE-3alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 14311
Homologene: 11128
Gm9830
Name: predicted gene 9830
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 100048057
VEGA: 9
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 38,818,059 bp
  • T to C, chromosome 1 at 75,196,347 bp
  • T to C, chromosome 1 at 75,533,853 bp
  • T to C, chromosome 1 at 93,337,524 bp
  • T to C, chromosome 1 at 171,461,641 bp
  • C to T, chromosome 2 at 25,292,463 bp
  • T to A, chromosome 2 at 26,951,745 bp
  • T to C, chromosome 2 at 29,936,061 bp
  • A to G, chromosome 2 at 104,789,901 bp
  • T to G, chromosome 2 at 174,426,576 bp
  • T to A, chromosome 2 at 181,822,677 bp
  • T to C, chromosome 3 at 92,025,730 bp
  • A to G, chromosome 3 at 95,746,647 bp
  • T to C, chromosome 3 at 130,182,819 bp
  • A to T, chromosome 4 at 112,136,064 bp
  • A to G, chromosome 4 at 118,448,580 bp
  • T to C, chromosome 4 at 155,858,127 bp
  • T to A, chromosome 5 at 120,954,488 bp
  • T to C, chromosome 5 at 134,214,128 bp
  • G to A, chromosome 6 at 91,890,894 bp
  • T to A, chromosome 6 at 110,914,371 bp
  • T to C, chromosome 6 at 113,434,734 bp
  • C to T, chromosome 6 at 122,739,793 bp
  • G to T, chromosome 6 at 122,833,271 bp
  • A to G, chromosome 7 at 4,752,075 bp
  • A to C, chromosome 7 at 16,237,615 bp
  • A to G, chromosome 7 at 23,343,100 bp
  • A to G, chromosome 7 at 45,051,325 bp
  • A to G, chromosome 7 at 55,935,863 bp
  • A to T, chromosome 7 at 109,457,589 bp
  • A to G, chromosome 7 at 126,870,768 bp
  • A to T, chromosome 7 at 140,637,916 bp
  • A to G, chromosome 7 at 145,267,342 bp
  • G to A, chromosome 8 at 85,359,060 bp
  • A to G, chromosome 8 at 123,296,306 bp
  • A to G, chromosome 9 at 3,430,973 bp
  • C to A, chromosome 9 at 31,419,049 bp
  • A to T, chromosome 9 at 44,464,424 bp
  • T to A, chromosome 9 at 45,066,432 bp
  • G to T, chromosome 9 at 59,947,281 bp
  • T to A, chromosome 9 at 64,330,908 bp
  • A to C, chromosome 9 at 107,620,498 bp
  • C to G, chromosome 10 at 34,098,811 bp
  • A to G, chromosome 11 at 62,783,809 bp
  • A to G, chromosome 11 at 73,776,551 bp
  • G to A, chromosome 11 at 75,391,192 bp
  • A to G, chromosome 11 at 84,243,339 bp
  • T to A, chromosome 11 at 98,890,732 bp
  • A to T, chromosome 11 at 118,482,671 bp
  • G to A, chromosome 12 at 10,375,449 bp
  • A to G, chromosome 12 at 98,802,307 bp
  • C to T, chromosome 12 at 101,053,566 bp
  • T to A, chromosome 13 at 60,749,342 bp
  • G to A, chromosome 13 at 66,987,858 bp
  • A to G, chromosome 13 at 100,616,795 bp
  • A to T, chromosome 13 at 113,317,695 bp
  • A to G, chromosome 14 at 68,507,912 bp
  • G to A, chromosome 15 at 27,881,342 bp
  • T to A, chromosome 15 at 76,334,691 bp
  • C to T, chromosome 15 at 102,108,934 bp
  • A to T, chromosome 16 at 85,800,390 bp
  • G to A, chromosome 17 at 25,883,778 bp
  • C to T, chromosome 17 at 43,311,163 bp
  • A to G, chromosome 17 at 71,514,270 bp
  • A to T, chromosome 18 at 5,058,205 bp
  • A to G, chromosome 18 at 20,471,127 bp
  • A to G, chromosome 18 at 43,792,771 bp
  • A to G, chromosome 18 at 67,226,859 bp
  • G to T, chromosome 18 at 67,421,259 bp
  • A to G, chromosome 18 at 80,765,769 bp
  • C to A, chromosome 19 at 33,780,395 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4775 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
041991-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.