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Strain Name:
C57BL/6J-MtgxR4709Btlr/Mmmh
Stock Number:
042018-MU
Citation ID:
RRID:MMRRC_042018-MU
Other Names:
R4709 (G1), C57BL/6J-MtgxR4709Btlr
Major Collection:

Strain Information

Myh9
Name: myosin, heavy polypeptide 9, non-muscle
Synonyms: D0Jmb2, E030044M24Rik, NMHC II-A, Myhn-1, Myhn1, myosin IIA, Fltn
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 17886
HGNC: HGNC:7579
Homologene: 129835
En1
Name: engrailed 1
Synonyms: Mo-en.1, En-1, engrailed-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13798
HGNC: HGNC:3342
Homologene: 50663
Odf2l
Name: outer dense fiber of sperm tails 2-like
Synonyms: 4733401D09Rik, 9630045K08Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 52184
Homologene: 12011
Cers2
Name: ceramide synthase 2
Synonyms: Trh3, 0610013I17Rik, CerS2, Lass2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 76893
Homologene: 39581
Fryl
Name: FRY like transcription coactivator
Synonyms: 2310004H21Rik, 2510002A14Rik, 9030227G01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72313
Homologene: 103956
Ldlrad3
Name: low density lipoprotein receptor class A domain containing 3
Synonyms: Lrad3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241576
Homologene: 18377
Smarcad1
Name: SNF2 related chromatin remodeling ATPase with DExD box 1
Synonyms: D6Pas1, Etl1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 13990
Homologene: 5301
Arhgap35
Name: Rho GTPase activating protein 35
Synonyms: P190 RhoGAP, 6430596G11Rik, p190RhoGAP, p190A, Grlf1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 232906
HGNC: HGNC:4591
Homologene: 35136
Plxna1
Name: plexin A1
Synonyms: NOV, Plxn1, 2600013D04Rik, PlexA1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 18844
HGNC: HGNC:9099
Homologene: 56426
Ptpn23
Name: protein tyrosine phosphatase, non-receptor type 23
Synonyms: PTP-TD14
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 104831
Homologene: 135706
Hectd1
Name: HECT domain E3 ubiquitin protein ligase 1
Synonyms: A630086P08Rik, opm, b2b327Clo
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 207304
VEGA: 12
Homologene: 9115
Stat1
Name: signal transducer and activator of transcription 1
Synonyms: 2010005J02Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20846
Homologene: 21428
Gtf2ird1
Name: general transcription factor II I repeat domain-containing 1
Synonyms: WBSCR11, Cream1, GTF3, MusTRD1, binding factor for early enhancer, BEN, ESTM9
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 57080
HGNC: HGNC:4661
Homologene: 4158
Stag1
Name: STAG1 cohesin complex component
Synonyms: SA-1, Scc3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20842
Homologene: 21191
Rlig1
Name: RNA 5'-phosphate and 3'-OH ligase 1
Synonyms: 4930430F08Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 68281
VEGA: 10
Homologene: 18409
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20191
VEGA: 13
Homologene: 37423
Zfp719
Name: zinc finger protein 719
Synonyms: C630016O21Rik, mszf6, 9430094P17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 210105
Nectin3
Name: nectin cell adhesion molecule 3
Synonyms: nectin-3, 4921513D19Rik, 2610301B19Rik, 3000002N23Rik, Pvrl3
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 58998
Homologene: 9162
Hey1
Name: hairy/enhancer-of-split related with YRPW motif 1
Synonyms: hesr-1, HRT1, Herp2, Hesr1, bHLHb31, CHF2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 15213
HGNC: HGNC:4880
Homologene: 7756
Grid2ip
Name: glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1
Synonyms: delphilin
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 170935
Homologene: 15781
Rtn4r
Name: reticulon 4 receptor
Synonyms: Nogo-66 receptor, NgR, NgR1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 65079
Homologene: 11299
Abcf1
Name: ATP-binding cassette, sub-family F member 1
Synonyms: Abc50, D17Wsu166e, GCN20
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224742
HGNC: HGNC:70
Homologene: 849
Grhl1
Name: grainyhead like transcription factor 1
Synonyms: p70 MGR, p61 MGR, LBP-32, Tcfcp2l2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 195733
VEGA: 12
Homologene: 32219
Rbm43
Name: RNA binding motif protein 43
Synonyms: 0610033I05Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71684
Homologene: 12715
Cnbp
Name: cellular nucleic acid binding protein
Synonyms: Znf9
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12785
Homologene: 2567
Khdrbs1
Name: KH domain containing, RNA binding, signal transduction associated 1
Synonyms: p62, Sam68
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 20218
Homologene: 4781
Incenp
Name: inner centromere protein
Synonyms: 2700067E22Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 16319
VEGA: 19
HGNC: HGNC:6058
Homologene: 9624
Map3k7
Name: mitogen-activated protein kinase kinase kinase 7
Synonyms: Tak1, TGF-beta activated kinase 1, transforming growth factor-beta-activated kinase 1, TAK1, transforming growth factor beta-activated kinase 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 26409
HGNC: HGNC:6859
Homologene: 118818
Pdlim1
Name: PDZ and LIM domain 1 (elfin)
Synonyms: mClim1, CLP36
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 54132
HGNC: HGNC:2067
Homologene: 9643
Arhgdia
Name: Rho GDP dissociation inhibitor alpha
Synonyms: 5330430M07Rik, Rho-GDI, Rho GDIalpha
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192662
HGNC: HGNC:678
Homologene: 908
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 94109
Homologene: 69536
Dhodh
Name: dihydroorotate dehydrogenase
Synonyms: 2810417D19Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 56749
HGNC: HGNC:2867
Homologene: 1043
Itgam
Name: integrin alpha M
Synonyms: complement component receptor 3 alpha, CD11B (p170), Mac-1 alpha, Mac-1, complement receptor type 3, CR3, CD11b/CD18, Mac-1a, F730045J24Rik, Ly-40, Cd11b
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16409
HGNC: HGNC:6149
Homologene: 526
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Acz, Pico
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 26875
Homologene: 69111
Ttc8
Name: tetratricopeptide repeat domain 8
Synonyms: 0610012F22Rik, BBS8
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 76260
Homologene: 14988
Dnah11
Name: dynein, axonemal, heavy chain 11
Synonyms: lrd, b2b598Clo, b2b1203Clo, b2b1279Clo, b2b1289Clo, b2b1727Clo, Dnahc11, avc4
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 13411
HGNC: HGNC:2942
Homologene: 2801
Ephb2
Name: Eph receptor B2
Synonyms: eteck, Erk, Tyro5, Prkm5, Nuk, Drt, Hek5, Sek3, Qek5, Cek5
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13844
HGNC: HGNC:3393
Homologene: 37925
Slc45a1
Name: solute carrier family 45, member 1
Synonyms: Dnb5
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242773
Homologene: 44908
Gm10800
Name: predicted gene 10800
Type: Gene
Species: Mouse
Chromosome: 2
Scube3
Name: signal peptide, CUB domain, EGF-like 3
Synonyms: D030038I21Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 268935
Homologene: 65059
Vmn2r26
Name: vomeronasal 2, receptor 26
Synonyms: V2r1b
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56552
Homologene: 135915
Or5h17
Name: olfactory receptor family 5 subfamily H member 17
Synonyms: GA_x54KRFPKG5P-55229158-55230087, MOR183-2, Olfr183
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 258478
Homologene: 27178
Ypel5
Name: yippee like 5
Synonyms: CGI-127, 2310076K21Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 383295
VEGA: 17
Homologene: 41097
Myo1c
Name: myosin IC
Synonyms: myosin-Ibeta, myr2, C80397, mm1beta
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17913
HGNC: HGNC:7597
Homologene: 32046
Slc4a10
Name: solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
Synonyms: NCBE
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 94229
Homologene: 23340
Or10d5
Name: olfactory receptor family 10 subfamily D member 5
Synonyms: GA_x6K02T2PVTD-33651220-33650288, MOR224-2, Olfr975
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258825
VEGA: 9
Homologene: 27275
Zyg11a
Name: zyg-11 family member A, cell cycle regulator
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230590
Homologene: 66294
Postn
Name: periostin, osteoblast specific factor
Synonyms: OSF-2, Periostin, Osf2, peri, A630052E07Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 50706
Homologene: 4730
Ranbp6
Name: RAN binding protein 6
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 240614
HGNC: HGNC:9851
Homologene: 18935
Hpx
Name: hemopexin
Synonyms: hx, Hpxn
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 15458
HGNC: HGNC:5171
Homologene: 511
Bpifb6
Name: BPI fold containing family B, member 6
Synonyms: LOC228796, Bpil3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228796
Homologene: 18375
Parp6
Name: poly (ADP-ribose) polymerase family, member 6
Synonyms: 2310028P13Rik, 1700119G14Rik, C030013N01Rik, 3110038K10Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 67287
VEGA: 9
Homologene: 10627
Or9i14
Name: olfactory receptor family 9 subfamily I member 14
Synonyms: GA_x6K02T2RE5P-4147744-4146800, MOR211-2, Olfr1499
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258792
Homologene: 17393
Gzmd
Name: granzyme D
Synonyms: CCP5, Ctla-5, Ctla5
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 14941
Homologene: 133275
Plxnc1
Name: plexin C1
Synonyms: vespr, 2510048K12Rik, CD232
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 54712
HGNC: HGNC:9106
Homologene: 4211
Pcdhb12
Name: protocadherin beta 12
Synonyms: Pcdhb5F, PcdhbL, Pcdh3
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93883
HGNC: HGNC:8690
Homologene: 87126
Atp8b3
Name: ATPase, class I, type 8B, member 3
Synonyms: SAPLT, 1700042F02Rik, 1700056N23Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67331
VEGA: 10
Homologene: 19034
Vmn2r118
Name: vomeronasal 2, receptor 118
Synonyms: EG668547, Vmn2r119, EG383258
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 383258
Homologene: 129687
Vmn2r96
Name: vomeronasal 2, receptor 96
Synonyms: EG433070
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 433070
Gimap3
Name: GTPase, IMAP family member 3
Synonyms: 2010110D23Rik, Ian4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 83408
Homologene: 41257
Nlrp4c
Name: NLR family, pyrin domain containing 4C
Synonyms: Nalp-alpha, Rnh2, Nalp4c
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 83564
Homologene: 75315
Or9a2
Name: olfactory receptor family 9 subfamily A member 2
Synonyms: GA_x6K02T2P3E9-5780974-5781915, MOR120-1, Olfr459
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 258569
Homologene: 83448
Vmn1r172
Name: vomeronasal 1 receptor 172
Synonyms: V3R9, V1rd9
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 81010
Homologene: 79577
Plscr2
Name: phospholipid scramblase 2
Synonyms: PL scramblase
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18828
Homologene: 134152
Cbr4
Name: carbonyl reductase 4
Synonyms: A730083J17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234309
Homologene: 57181
Nek5
Name: NIMA (never in mitosis gene a)-related expressed kinase 5
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 330721
HGNC: HGNC:7748
Homologene: 87952
Or2at1
Name: olfactory receptor family 2 subfamily AT member 1
Synonyms: GA_x6K02T2PBJ9-2443810-2444775, MOR101-2, Olfr521
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258353
Homologene: 128108
Gtf2h2
Name: general transcription factor II H, polypeptide 2
Synonyms: Btf2p44, basal transcription factor 2, p44 subunit, 44kDa, p44
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 23894
Homologene: 1159
Pfkfb3
Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Synonyms: E330010H22Rik, uPFK-2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 170768
HGNC: HGNC:8874
Homologene: 88708
Sbk2
Name: SH3-binding domain kinase family, member 2
Synonyms: LOC381836
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 381836
Homologene: 30927
Or2ak4
Name: olfactory receptor family 2 subfamily AK member 4
Synonyms: GA_x6K02T2NKPP-648708-647788, MOR285-3P, MOR285-6_p, Olfr316
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258064
Homologene: 133825
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 52,126,521 bp
  • A to T, chromosome 1 at 120,607,143 bp
  • G to A, chromosome 2 at 11,493,908 bp
  • A to T, chromosome 2 at 51,929,716 bp
  • A to G, chromosome 2 at 62,257,517 bp
  • A to G, chromosome 2 at 76,752,084 bp
  • T to G, chromosome 2 at 98,663,901 bp
  • A to G, chromosome 2 at 102,069,998 bp
  • T to A, chromosome 2 at 153,908,516 bp
  • A to G, chromosome 3 at 8,665,903 bp
  • T to A, chromosome 3 at 54,384,610 bp
  • A to G, chromosome 3 at 95,320,223 bp
  • G to A, chromosome 3 at 145,136,714 bp
  • G to T, chromosome 4 at 31,985,700 bp
  • T to C, chromosome 4 at 108,205,071 bp
  • A to T, chromosome 4 at 129,741,942 bp
  • C to A, chromosome 4 at 136,696,052 bp
  • G to A, chromosome 4 at 150,638,240 bp
  • A to G, chromosome 5 at 14,778,558 bp
  • A to G, chromosome 5 at 73,080,972 bp
  • T to C, chromosome 5 at 134,404,734 bp
  • T to A, chromosome 5 at 143,388,903 bp
  • G to T, chromosome 6 at 41,771,508 bp
  • A to T, chromosome 6 at 48,765,393 bp
  • A to G, chromosome 6 at 65,075,115 bp
  • C to A, chromosome 6 at 84,097,715 bp
  • A to T, chromosome 6 at 87,844,138 bp
  • T to C, chromosome 6 at 89,334,751 bp
  • A to G, chromosome 6 at 124,053,965 bp
  • G to T, chromosome 7 at 4,957,578 bp
  • T to A, chromosome 7 at 6,065,425 bp
  • C to T, chromosome 7 at 16,563,586 bp
  • A to G, chromosome 7 at 23,660,181 bp
  • C to T, chromosome 7 at 43,590,232 bp
  • A to T, chromosome 7 at 99,767,782 bp
  • A to G, chromosome 7 at 105,600,036 bp
  • T to C, chromosome 7 at 128,101,537 bp
  • A to T, chromosome 8 at 16,023,891 bp
  • A to G, chromosome 8 at 16,710,506 bp
  • A to T, chromosome 8 at 22,083,427 bp
  • T to C, chromosome 8 at 61,490,027 bp
  • T to C, chromosome 8 at 109,601,538 bp
  • A to T, chromosome 9 at 39,949,869 bp
  • T to C, chromosome 9 at 59,641,769 bp
  • A to G, chromosome 9 at 92,291,014 bp
  • G to T, chromosome 9 at 100,738,039 bp
  • A to G, chromosome 9 at 110,388,856 bp
  • T to C, chromosome 10 at 80,536,770 bp
  • A to G, chromosome 10 at 94,843,768 bp
  • T to C, chromosome 10 at 100,578,381 bp
  • G to A, chromosome 11 at 3,524,663 bp
  • T to C, chromosome 11 at 58,758,187 bp
  • C to T, chromosome 11 at 75,670,030 bp
  • A to G, chromosome 11 at 120,579,691 bp
  • A to G, chromosome 12 at 24,586,133 bp
  • A to G, chromosome 12 at 51,787,912 bp
  • A to T, chromosome 12 at 98,979,825 bp
  • T to A, chromosome 12 at 118,018,760 bp
  • A to G, chromosome 13 at 11,716,998 bp
  • G to T, chromosome 13 at 100,469,015 bp
  • T to C, chromosome 14 at 56,130,241 bp
  • A to T, chromosome 15 at 77,787,517 bp
  • A to G, chromosome 16 at 18,151,182 bp
  • T to A, chromosome 16 at 46,463,943 bp
  • A to T, chromosome 16 at 59,000,095 bp
  • T to C, chromosome 17 at 18,582,826 bp
  • G to A, chromosome 17 at 28,167,192 bp
  • G to A, chromosome 17 at 35,960,177 bp
  • A to T, chromosome 17 at 55,610,860 bp
  • G to A, chromosome 17 at 72,848,731 bp
  • A to G, chromosome 18 at 37,437,495 bp
  • G to A, chromosome 19 at 9,876,600 bp
  • T to A, chromosome 19 at 13,815,450 bp
  • C to T, chromosome 19 at 29,811,584 bp
  • T to A, chromosome 19 at 40,222,736 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4709 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
042018-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.