Strain Name:
C57BL/6J-MtgxR4765Btlr/Mmmh
Stock Number:
042406-MU
Citation ID:
RRID:MMRRC_042406-MU
Other Names:
R4765 (G1), C57BL/6J-MtgxR4765Btlr
Major Collection:

Strain Information

Ubn2
Name: ubinuclein 2
Synonyms: 2900060J04Rik, D130059P03Rik, 6030408G03Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 320538
Homologene: 45564
Mrtfb
Name: myocardin related transcription factor B
Synonyms: MRTF-B, Mkl2, Mrtfb, Gt4-1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 239719
Homologene: 40917
Gpr37
Name: G protein-coupled receptor 37
Synonyms: Pael-R, parkin-associated endothelin B-like receptor
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14763
HGNC: HGNC:4494
Homologene: 3875
Vldlr
Name: very low density lipoprotein receptor
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 22359
Homologene: 443
Slc4a7
Name: solute carrier family 4, sodium bicarbonate cotransporter, member 7
Synonyms: NBCn1, NBC3, E430014N10Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218756
VEGA: 14
Homologene: 2680
Foxj2
Name: forkhead box J2
Synonyms: Fhx
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 60611
Homologene: 10187
Stk11ip
Name: serine/threonine kinase 11 interacting protein
Synonyms: LKB1IP, 1200014D22Rik, LIP1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 71728
Homologene: 12406
Hcn4
Name: hyperpolarization-activated, cyclic nucleotide-gated K+ 4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 330953
VEGA: 9
Homologene: 3997
Enpp2
Name: ectonucleotide pyrophosphatase/phosphodiesterase 2
Synonyms: Autotaxin, Npps2, PD-Ialpha, ATX, Pdnp2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 18606
HGNC: HGNC:3357
Homologene: 4526
Uhmk1
Name: U2AF homology motif (UHM) kinase 1
Synonyms: KIS, C820018A03Rik, OTTMUSG00000021542, Kist
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16589
Homologene: 7801
Scn8a
Name: sodium channel, voltage-gated, type VIII, alpha
Synonyms: nmf58, med, motor end-plate disease, Nav1.6, nmf2, NMF335, ataxia 3, NaCh6, seal, mnd2, nmf335, nur14, mnd-2, C630029C19Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20273
Homologene: 7927
Depdc5
Name: DEP domain containing 5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 277854
Homologene: 34718
Ubr1
Name: ubiquitin protein ligase E3 component n-recognin 1
Synonyms: E3 alpha
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22222
Homologene: 7582
Bend3
Name: BEN domain containing 3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 331623
VEGA: 10
Homologene: 19511
Spast
Name: spastin
Synonyms: Spg4
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 50850
VEGA: 17
Homologene: 8970
Ankfy1
Name: ankyrin repeat and FYVE domain containing 1
Synonyms: Ankhzn
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11736
Homologene: 9491
Pole2
Name: polymerase (DNA directed), epsilon 2 (p59 subunit)
Synonyms: DNA polymerase epsilon small subunit
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 18974
VEGA: 12
HGNC: HGNC:9178
Homologene: 2015
Sin3a
Name: transcriptional regulator, SIN3A (yeast)
Synonyms: mSin3A, Sin3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20466
Homologene: 32124
Fermt2
Name: fermitin family member 2
Synonyms: Plekhc1, Kindlin-2, Mig2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218952
Homologene: 4976
Afg3l2
Name: AFG3-like AAA ATPase 2
Synonyms: 2310036I02Rik, par, Emv66
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 69597
VEGA: 18
HGNC: HGNC:315
Homologene: 4947
Dtymk
Name: deoxythymidylate kinase
Synonyms: D10Ertd203e, CDC8, Tmk, TYPK, mtmk
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 21915
HGNC: HGNC:3061
Homologene: 6285
Bicc1
Name: BicC family RNA binding protein 1
Synonyms: Bic-C, jcpk
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 83675
Homologene: 12856
Vps50
Name: VPS50 EARP/GARPII complex subunit
Synonyms: Ccdc132, 8430415E05Rik, 1700034M03Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 73288
Homologene: 11498
Scyl2
Name: SCY1-like 2 (S. cerevisiae)
Synonyms: D10Ertd802e, CVAK104
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 213326
Homologene: 13349
Cpsf2
Name: cleavage and polyadenylation specific factor 2
Synonyms: 100kDa, 2610024B04Rik, Cpsf
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 51786
VEGA: 12
HGNC: HGNC:2325
Homologene: 6460
Shoc2
Name: Shoc2, leucine rich repeat scaffold protein
Synonyms: soc-2 (suppressor of clear) homolog (C. elegans), Sur-8
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 56392
VEGA: 19
Homologene: 7219
2810021J22Rik
Name: RIKEN cDNA 2810021J22 gene
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69944
Homologene: 138400
Mei1
Name: meiotic double-stranded break formation protein 1
Synonyms: mei1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 74369
Homologene: 46535
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: DHC1b, m152Asp, b2b414Clo, D030010H02Rik, D330044F14Rik, Dnchc2, DHC2, 4432416O06Rik, m407Asp
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Drg1
Name: developmentally regulated GTP binding protein 1
Synonyms: Nedd3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 13494
HGNC: HGNC:3029
Homologene: 3060
Azi2
Name: 5-azacytidine induced gene 2
Synonyms: AZ2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 27215
Homologene: 8443
Elac2
Name: elaC ribonuclease Z 2
Synonyms: tRNase Z(L), 1110017O07Rik, D11Wsu80e
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 68626
Homologene: 6403
Gps2
Name: G protein pathway suppressor 2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 56310
HGNC: HGNC:4550
Homologene: 49599
Chd6
Name: chromodomain helicase DNA binding protein 6
Synonyms: 5430439G14Rik, 6330406J24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71389
Homologene: 32772
Katnal2
Name: katanin p60 subunit A-like 2
Synonyms: 4933439B08Rik, 3110023G01Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 71206
Homologene: 41725
Dnaja3
Name: DnaJ heat shock protein family (Hsp40) member A3
Synonyms: Tid-1, 1810053A11Rik, 1200003J13Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 83945
Homologene: 36170
Dennd1a
Name: DENN domain containing 1A
Synonyms: 6030446I19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227801
Homologene: 17141
Tnrc6c
Name: trinucleotide repeat containing 6C
Synonyms: 9930033H14Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217351
Homologene: 23137
Thoc6
Name: THO complex 6
Synonyms: F830014G06Rik, Wdr58
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 386612
Homologene: 11533
Zfhx4
Name: zinc finger homeodomain 4
Synonyms: C130041O22Rik, Zfh4, Zfh-4
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 80892
Homologene: 23477
Acta2
Name: actin alpha 2, smooth muscle, aorta
Synonyms: SMAalpha, alphaSMA, Actvs, SMalphaA, 0610041G09Rik, a-SMA
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 11475
VEGA: 19
HGNC: HGNC:130
Homologene: 133938
Ttn
Name: titin
Synonyms: connectin, 1100001C23Rik, D330041I19Rik, D830007G01Rik, 2310074I15Rik, 2310036G12Rik, mdm, 2310057K23Rik, shru, L56
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Fat2
Name: FAT atypical cadherin 2
Synonyms: Fath2, EMI2, LOC245827, mKIAA0811
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 245827
HGNC: HGNC:3596
Homologene: 1110
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: Mgr1, Gpr98, Mass1, VLGR1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 110789
Homologene: 19815
Megf10
Name: multiple EGF-like-domains 10
Synonyms: LOC240312, 3000002B06Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 70417
Homologene: 23771
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: Dnahc9, D11Ertd686e
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Hfm1
Name: HFM1, ATP-dependent DNA helicase homolog
Synonyms: A330009G12Rik, LOC381663, Mer3, Sec63d1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 330149
Homologene: 87103
Ephb3
Name: Eph receptor B3
Synonyms: HEK2, Sek4, MDK5, Cek10, Etk2, Tyro6
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 13845
HGNC: HGNC:3394
Homologene: 20938
D430041D05Rik
Name: RIKEN cDNA D430041D05 gene
Synonyms: G2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241589
Homologene: 115928
Slc26a2
Name: solute carrier family 26 (sulfate transporter), member 2
Synonyms: ST-OB, Dtd
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13521
Homologene: 73876
Abcb11
Name: ATP-binding cassette, sub-family B member 11
Synonyms: sister of P-glycoprotein, PGY4, ABC16, PFIC2, Lith1, Bsep
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 27413
HGNC: HGNC:42
Homologene: 74509
Myo7b
Name: myosin VIIB
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 17922
HGNC: HGNC:7607
Homologene: 81947
Vmn2r25
Name: vomeronasal 2, receptor 25
Synonyms: EG545874
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 545874
Homologene: 135915
Igsf10
Name: immunoglobulin superfamily, member 10
Synonyms: CMF608, Adlican2, 6530405F15Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 242050
Homologene: 18712
Cyp4a12a
Name: cytochrome P450, family 4, subfamily a, polypeptide 12a
Synonyms: Cyp4a12
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 277753
Homologene: 134044
Tnfrsf8
Name: tumor necrosis factor receptor superfamily, member 8
Synonyms: CD30
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21941
Homologene: 949
Sp100
Name: nuclear antigen Sp100
Synonyms: A430075G10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20684
Homologene: 86761
Snx19
Name: sorting nexin 19
Synonyms: 3526401K03Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 102607
VEGA: 9
Homologene: 8846
Gadl1
Name: glutamate decarboxylase-like 1
Synonyms: 1110027M19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73748
Homologene: 45812
Drc1
Name: dynein regulatory complex subunit 1
Synonyms: Ccdc164, b2b1654Clo, Gm1060, LOC381738
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 381738
Homologene: 35977
Serpina3f
Name: serine (or cysteine) peptidase inhibitor, clade A, member 3F
Synonyms: antitrypsin, alpha-1 antiproteinasin, 2A1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238393
HGNC: HGNC:16
Homologene: 115927
Kctd8
Name: potassium channel tetramerisation domain containing 8
Synonyms: A730087N02Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 243043
Homologene: 18464
Cenpj
Name: centromere protein J
Synonyms: Sas4, 4932437H03Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 219103
Homologene: 10204
Or5b24
Name: olfactory receptor family 5 subfamily B member 24
Synonyms: GA_x6K02T2RE5P-3264213-3265157, Olfr1449, MOR202-34
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258300
Homologene: 17184
Xrra1
Name: X-ray radiation resistance associated 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 446101
Homologene: 19547
Nfkbiz
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
Synonyms: Mail
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 80859
Homologene: 12734
Cdh10
Name: cadherin 10
Synonyms: T2-cadherin, C030003B10Rik, C030011H18Rik, A830016G23Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 320873
HGNC: HGNC:1749
Homologene: 68530
Lrp8
Name: low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
Synonyms: 4932703M08Rik, apoER2, Lr8b
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 16975
HGNC: HGNC:6700
Homologene: 31250
Vmn1r1
Name: vomeronasal 1 receptor 1
Synonyms: Gm6628
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 625823
Homologene: 83459
Gata6
Name: GATA binding protein 6
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 14465
VEGA: 18
HGNC: HGNC:4174
Homologene: 68449
Or4b13
Name: olfactory receptor family 4 subfamily B member 13
Synonyms: MOR227-2, GA_x6K02T2Q125-51607674-51606757, K20, Olfr142
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 406186
HGNC: HGNC:8290
Homologene: 45081
Commd2
Name: COMM domain containing 2
Synonyms: 1190017G07Rik, HSPC042, D3Ertd176e
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 52245
Homologene: 9381
Zscan4d
Name: zinc finger and SCAN domain containing 4D
Synonyms: EG545913
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 545913
Homologene: 85986
Rad9a
Name: RAD9 checkpoint clamp component A
Synonyms: Rad9
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 19367
VEGA: 19
HGNC: HGNC:9827
Homologene: 32118
Slc5a6
Name: solute carrier family 5 (sodium-dependent vitamin transporter), member 6
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 330064
Homologene: 23277
Gm16503
Name: predicted gene 16503
Type: Gene
Species: Mouse
Chromosome: 4
Cflar
Name: CASP8 and FADD-like apoptosis regulator
Synonyms: Flip, 2310024N18Rik, A430105C05Rik, c-Flip, Cash, Casper
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12633
HGNC: HGNC:1876
Homologene: 7652
Ly6l
Name: lymphocyte antigen 6 family member L
Synonyms: Gm20654
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 102637705
Homologene: 140539
Gm6866
Name: predicted gene 6866
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 628304
Homologene: 80005
Mark1-ps3
Name: MAP/microtubule affinity-regulating kinase 1, pseudogene 3
Synonyms: Gm19518
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Gm14455
Name: predicted gene 14455
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 118568483
AC146980.1
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Sprr4
Name: small proline-rich protein 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229562
E030037K01Rik
Name: RIKEN cDNA E030037K01 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Pcdhgc5
Name: protocadherin gamma subfamily C, 5
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93708
HGNC: HGNC:8718
Homologene: 110933
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 58,732,321 bp
  • T to G, chromosome 1 at 75,527,155 bp
  • T to C, chromosome 1 at 85,694,275 bp
  • T to C, chromosome 1 at 93,792,909 bp
  • T to C, chromosome 1 at 170,199,901 bp
  • C to T, chromosome 1 at 182,157,906 bp
  • G to A, chromosome 2 at 38,159,780 bp
  • A to T, chromosome 2 at 69,245,867 bp
  • A to G, chromosome 2 at 76,710,987 bp
  • T to C, chromosome 2 at 76,772,507 bp
  • T to A, chromosome 2 at 90,252,463 bp
  • T to A, chromosome 2 at 104,214,096 bp
  • A to T, chromosome 2 at 120,963,442 bp
  • A to T, chromosome 2 at 160,966,244 bp
  • A to C, chromosome 2 at 172,427,559 bp
  • T to C, chromosome 3 at 5,400,152 bp
  • A to G, chromosome 3 at 40,802,022 bp
  • A to T, chromosome 3 at 57,651,397 bp
  • A to T, chromosome 3 at 59,329,705 bp
  • G to A, chromosome 3 at 92,500,409 bp
  • T to C, chromosome 4 at 107,854,395 bp
  • A to G, chromosome 4 at 115,326,191 bp
  • A to T, chromosome 4 at 145,296,877 bp
  • G to T, chromosome 4 at 147,541,097 bp
  • G to T, chromosome 5 at 30,348,731 bp
  • A to T, chromosome 5 at 31,038,083 bp
  • A to C, chromosome 5 at 32,937,635 bp
  • T to C, chromosome 5 at 69,340,848 bp
  • T to A, chromosome 5 at 106,842,539 bp
  • C to T, chromosome 6 at 3,578,885 bp
  • T to G, chromosome 6 at 25,669,108 bp
  • T to A, chromosome 6 at 38,479,140 bp
  • G to T, chromosome 6 at 122,833,271 bp
  • C to T, chromosome 6 at 123,823,223 bp
  • T to A, chromosome 7 at 11,162,667 bp
  • G to T, chromosome 7 at 41,216,118 bp
  • T to C, chromosome 7 at 99,906,568 bp
  • C to A, chromosome 8 at 47,713,547 bp
  • A to G, chromosome 9 at 7,157,591 bp
  • A to C, chromosome 9 at 30,440,157 bp
  • G to A, chromosome 9 at 57,096,803 bp
  • A to T, chromosome 9 at 58,857,977 bp
  • A to G, chromosome 9 at 115,966,313 bp
  • A to T, chromosome 9 at 118,061,471 bp
  • A to T, chromosome 10 at 43,510,750 bp
  • T to C, chromosome 10 at 70,940,593 bp
  • C to T, chromosome 10 at 89,659,298 bp
  • T to C, chromosome 11 at 3,250,280 bp
  • T to C, chromosome 11 at 55,281,187 bp
  • C to T, chromosome 11 at 58,881,161 bp
  • T to G, chromosome 11 at 64,992,222 bp
  • C to T, chromosome 11 at 65,927,726 bp
  • T to C, chromosome 11 at 69,916,361 bp
  • T to G, chromosome 11 at 72,712,291 bp
  • A to G, chromosome 11 at 117,742,927 bp
  • A to T, chromosome 12 at 69,222,052 bp
  • A to G, chromosome 12 at 101,997,440 bp
  • G to C, chromosome 12 at 104,219,431 bp
  • A to G, chromosome 13 at 81,106,919 bp
  • T to G, chromosome 14 at 14,762,414 bp
  • G to T, chromosome 14 at 45,462,236 bp
  • G to A, chromosome 14 at 56,549,545 bp
  • G to T, chromosome 15 at 19,013,278 bp
  • A to G, chromosome 15 at 54,875,672 bp
  • A to T, chromosome 15 at 75,449,694 bp
  • A to T, chromosome 15 at 82,112,485 bp
  • A to G, chromosome 15 at 101,040,471 bp
  • T to A, chromosome 16 at 4,693,432 bp
  • C to A, chromosome 16 at 13,412,594 bp
  • T to C, chromosome 16 at 21,222,092 bp
  • T to C, chromosome 16 at 55,819,024 bp
  • A to G, chromosome 17 at 23,670,888 bp
  • G to T, chromosome 17 at 53,724,960 bp
  • C to A, chromosome 17 at 74,369,216 bp
  • A to G, chromosome 18 at 11,054,394 bp
  • G to C, chromosome 18 at 31,961,900 bp
  • T to C, chromosome 18 at 37,822,069 bp
  • A to T, chromosome 18 at 57,287,794 bp
  • A to T, chromosome 18 at 61,199,486 bp
  • G to T, chromosome 18 at 67,421,259 bp
  • C to T, chromosome 18 at 76,977,543 bp
  • C to A, chromosome 19 at 4,200,489 bp
  • T to C, chromosome 19 at 12,935,076 bp
  • T to C, chromosome 19 at 27,240,547 bp
  • T to C, chromosome 19 at 34,246,152 bp
  • A to G, chromosome 19 at 53,988,303 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4765 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
042406-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.