Strain Name:
C57BL/6J-MtgxR4870Btlr/Mmmh
Stock Number:
042480-MU
Citation ID:
RRID:MMRRC_042480-MU
Other Names:
R4870 (G1), C57BL/6J-MtgxR4870Btlr
Major Collection:

Gene Information

Kif3c
Name: kinesin family member 3C
Synonyms: N-4 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 16570
VEGA: 12
HGNC: HGNC:6321
Homologene: 55640
Th
Name: tyrosine hydroxylase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 21823
Homologene: 307
Vcan
Name: versican
Synonyms: 5430420N07Rik, heart defect, DPEAAE, hdf, PG-M, Cspg2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 13003
HGNC: HGNC:2464
Homologene: 3228
Cyp11b2
Name: cytochrome P450, family 11, subfamily b, polypeptide 2
Synonyms: Cyp11b-2, Cyp11b, steroid-11-beta-hydroxylase, aldosterone synthase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 13072
Homologene: 128035
Trp53bp1
Name: transformation related protein 53 binding protein 1
Synonyms: p53BP1, 53BP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 27223
Homologene: 4137
Abcc8
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 8
Synonyms: D930031B21Rik, SUR1, Sur
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20927
HGNC: HGNC:59
Homologene: 68048
Znfx1
Name: zinc finger, NFX1-type containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 98999
Homologene: 10877
Dnmt3b
Name: DNA methyltransferase 3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 13436
HGNC: HGNC:2979
Homologene: 56000
Dip2b
Name: disco interacting protein 2 homolog B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239667
Homologene: 72227
Ttc17
Name: tetratricopeptide repeat domain 17
Synonyms: D2Bwg1005e, 9130020K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74569
Homologene: 10100
Knl1
Name: kinetochore scaffold 1
Synonyms: 2310043D08Rik, Casc5, 5730505K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 76464
Homologene: 44890
Ankle2
Name: ankyrin repeat and LEM domain containing 2
Synonyms: 1110001J12Rik, D5Ertd585e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71782
Homologene: 35424
Trrap
Name: transformation/transcription domain-associated protein
Synonyms: transactivation/transformation-domain associated protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100683
Homologene: 39246
Clcn7
Name: chloride channel, voltage-sensitive 7
Synonyms: ClC-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 26373
HGNC: HGNC:2025
Homologene: 56546
Zfp292
Name: zinc finger protein 292
Synonyms: Zn-15, Krox-10, Zfp15, Zfp-15, 9430062L07Rik, Zn-16, 5730450D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 30046
Homologene: 8493
F2rl1
Name: coagulation factor II (thrombin) receptor-like 1
Synonyms: Protease-activated receptor-2, Gpcr11, PAR-2, Par2, proteinase-activated receptor-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 14063
VEGA: 13
HGNC: HGNC:3538
Homologene: 21087
Mcm10
Name: minichromosome maintenance 10 replication initiation factor
Synonyms: C330019M07Rik, 2410041F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 70024
Homologene: 41275
Tenm2
Name: teneurin transmembrane protein 2
Synonyms: D3Bwg1534e, 9330187F13Rik, Odz2, Ten-m2, 2610040L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 23964
Homologene: 22672
Ubn1
Name: ubinuclein 1
Synonyms: 2610108L02Rik, 1110029L11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 170644
VEGA: 16
Homologene: 9656
Gpbp1l1
Name: GC-rich promoter binding protein 1-like 1
Synonyms: 5330440M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 77110
Homologene: 84840
Pirb
Name: paired Ig-like receptor B
Synonyms: Gp91, Lilrb3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18733
HGNC: HGNC:6607
Homologene: 134028
Ntn1
Name: netrin 1
Synonyms: Netrin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18208
HGNC: HGNC:8029
Homologene: 21008
Dnajc14
Name: DnaJ heat shock protein family (Hsp40) member C14
Synonyms: DRIP78, 5730551F12Rik, HDJ3, LIP6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 74330
VEGA: 10
Homologene: 12553
Acsf2
Name: acyl-CoA synthetase family member 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 264895
Homologene: 23519
Tax1bp1
Name: Tax1 (human T cell leukemia virus type I) binding protein 1
Synonyms: 1700069J21Rik, TXBP151, T6BP, D6Ertd772e, 1200003J11Rik, D6Ertd404e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 52440
Homologene: 4395
Dmrt1
Name: doublesex and mab-3 related transcription factor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 50796
HGNC: HGNC:2934
Homologene: 9280
Csnk1d
Name: casein kinase 1, delta
Synonyms: 1200006A05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 104318
HGNC: HGNC:2452
Homologene: 74841
Tmem68
Name: transmembrane protein 68
Synonyms: 2010300G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 72098
Homologene: 12440
Ints7
Name: integrator complex subunit 7
Synonyms: 5930412E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 77065
Homologene: 9136
Gm7102
Name: predicted gene 7102
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 633057
Limd2
Name: LIM domain containing 2
Synonyms: 0610025L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67803
Homologene: 12731
Ppp1r12b
Name: protein phosphatase 1, regulatory subunit 12B
Synonyms: 1810037O03Rik, 9530009M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329251
HGNC: HGNC:7619
Homologene: 135710
Nr4a3
Name: nuclear receptor subfamily 4, group A, member 3
Synonyms: TEC, Nor1, MINOR, NOR-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18124
HGNC: HGNC:7982
Homologene: 5074
H2-T22
Name: histocompatibility 2, T region locus 22
Synonyms: H-2T22, H-2T17, H2-T17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 15039
Homologene: 79525
Isl1
Name: ISL1 transcription factor, LIM/homeodomain
Synonyms: Islet 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 16392
HGNC: HGNC:6132
Homologene: 1661
Cilp
Name: cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
Synonyms: C130036G17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 214425
HGNC: HGNC:1980
Homologene: 2679
Ceacam18
Name: carcinoembryonic antigen-related cell adhesion molecule 18
Synonyms: 2010110O04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 72431
Homologene: 48111
Garre1
Name: granule associated Rac and RHOG effector 1
Synonyms: 4931406P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233103
Homologene: 8795
Insrr
Name: insulin receptor-related receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 23920
HGNC: HGNC:6093
Homologene: 56539
Ptpro
Name: protein tyrosine phosphatase, receptor type, O
Synonyms: PTP-oc, GLEPP1, D28, PTP-U2, PTP-BK, PTP-phi, PTPROt, Ptpn15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 19277
HGNC: HGNC:9678
Homologene: 21564
Abcb11
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 11
Synonyms: Bsep, PGY4, ABC16, PFIC2, Lith1, sister of P-glycoprotein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 27413
HGNC: HGNC:42
Homologene: 74509
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: OTTMUSG00000005786, LOC380698
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380698
Homologene: 70869
Stab1
Name: stabilin 1
Synonyms: MS-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 192187
Homologene: 9035
Trp63
Name: transformation related protein 63
Synonyms: deltaNp63, KET protein, p63, p73L, TAp63, p51/p63, Trp53rp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 22061
Homologene: 31189
Plcl2
Name: phospholipase C-like 2
Synonyms: Plce2, PRIP-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224860
VEGA: 17
HGNC: HGNC:9064
Homologene: 9052
Sytl2
Name: synaptotagmin-like 2
Synonyms: Slp2-b, Slp2-d, Slp2-c, Slp2, Slp2-a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 83671
Homologene: 131343
Vmn2r58
Name: vomeronasal 2, receptor 58
Synonyms: EG628422
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 628422
Urad
Name: ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5) decarboxylase
Synonyms: EG231903, Prhoxnb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231903
Homologene: 82563
Zfp955a
Name: zinc finger protein 955A
Synonyms: AI842447
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 77652
VEGA: 17
Homologene: 104925
Lats1
Name: large tumor suppressor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16798
VEGA: 10
HGNC: HGNC:6514
Homologene: 55843
Simc1
Name: SUMO-interacting motifs containing 1
Synonyms: 4732471D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 319719
Homologene: 131217
Tssk4
Name: testis-specific serine kinase 4
Synonyms: 4933424F08Rik, 1700020B19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 71099
VEGA: 14
Homologene: 57078
Olfr1161
Name: olfactory receptor 1161
Synonyms: MOR174-2, GA_x6K02T2Q125-49516664-49517629
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258845
Homologene: 138318
H2-Q10
Name: histocompatibility 2, Q region locus 10
Synonyms: Q10, H-2Q10, Qa10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 15007
HGNC: HGNC:4931
Homologene: 128352
Galk2
Name: galactokinase 2
Synonyms: Gk2, 2810017M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 69976
HGNC: HGNC:4119
Homologene: 13654
Rita1
Name: RBPJ interacting and tubulin associated 1
Synonyms: 1110008J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100764
Homologene: 12585
Tmem44
Name: transmembrane protein 44
Synonyms: 1700007N03Rik, 9330161C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224090
Homologene: 26702
Mixl1
Name: Mix1 homeobox-like 1 (Xenopus laevis)
Synonyms: Mml
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 27217
Homologene: 8445
Vmn2r69
Name: vomeronasal 2, receptor 69
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 330581
Homologene: 115466
Alox8
Name: arachidonate 8-lipoxygenase
Synonyms: 8S-LOX, 8S-lipoxygenase, Alox15b, 8-LOX
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11688
HGNC: HGNC:434
Homologene: 886
Ndufaf6
Name: NADH:ubiquinone oxidoreductase complex assembly factor 6
Synonyms: 2310030N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 76947
Homologene: 43831
Mob1a
Name: MOB kinase activator 1A
Synonyms: Mobkl1b, 4022402H07Rik, Mobk1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232157
Homologene: 10076
Mipep
Name: mitochondrial intermediate peptidase
Synonyms: 5730405E07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 70478
VEGA: 14
HGNC: HGNC:7104
Homologene: 4337
Mmp21
Name: matrix metallopeptidase 21
Synonyms: b2b2458Clo, b2b873Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 214766
Homologene: 17519
Cdc14a
Name: CDC14 cell division cycle 14A
Synonyms: Cdc14, A830059A17Rik, CDC14A2, CDC14a1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229776
HGNC: HGNC:1718
Homologene: 75343
Rptn
Name: repetin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20129
Homologene: 84780
Exoc3l2
Name: exocyst complex component 3-like 2
Synonyms: Gm19857, 4933417E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74463
Homologene: 16328
Tsen34
Name: tRNA splicing endonuclease subunit 34
Synonyms: 0610027F08Rik, Leng5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 66078
Homologene: 44182
Olfr603
Name: olfactory receptor 603
Synonyms: MOR32-14_i, MOR32-2, GA_x6K02T2PBJ9-6096387-6095449, GA_x6K02T2PBJ9-6092550-6092362, Olfr604
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259073
Homologene: 121535
Ttll2
Name: tubulin tyrosine ligase-like family, member 2
Synonyms: EG625850
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 100216474
VEGA: 17
Homologene: 12917
Kcng2
Name: potassium voltage-gated channel, subfamily G, member 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240444
HGNC: HGNC:6249
Homologene: 8178
Pcdha11
Name: protocadherin alpha 11
Synonyms: A830022B16Rik, Crnr7, Cnr7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 12942
HGNC: HGNC:8665
Homologene: 75095
Gm26658
Name: predicted gene, 26658
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 134,949,033 bp
  • A to G, chromosome 1 at 180,694,672 bp
  • A to G, chromosome 1 at 191,596,331 bp
  • A to T, chromosome 2 at 5,004,159 bp
  • A to T, chromosome 2 at 69,239,196 bp
  • T to C, chromosome 2 at 88,025,460 bp
  • A to T, chromosome 2 at 94,366,609 bp
  • A to G, chromosome 2 at 119,081,513 bp
  • A to G, chromosome 2 at 121,256,641 bp
  • C to G, chromosome 2 at 125,929,637 bp
  • A to G, chromosome 2 at 153,670,364 bp
  • A to C, chromosome 2 at 167,055,269 bp
  • G to A, chromosome 3 at 87,811,604 bp
  • A to T, chromosome 3 at 93,396,469 bp
  • A to G, chromosome 3 at 116,423,460 bp
  • A to G, chromosome 4 at 3,569,500 bp
  • T to C, chromosome 4 at 11,060,917 bp
  • A to G, chromosome 4 at 34,808,917 bp
  • A to T, chromosome 4 at 48,051,651 bp
  • A to G, chromosome 4 at 116,573,517 bp
  • T to A, chromosome 5 at 110,251,478 bp
  • T to A, chromosome 5 at 120,611,383 bp
  • C to T, chromosome 5 at 144,833,311 bp
  • T to A, chromosome 5 at 147,315,454 bp
  • A to G, chromosome 6 at 52,729,493 bp
  • T to C, chromosome 6 at 83,340,239 bp
  • A to G, chromosome 6 at 137,377,132 bp
  • T to C, chromosome 7 at 3,694,381 bp
  • T to A, chromosome 7 at 3,712,662 bp
  • T to A, chromosome 7 at 19,495,192 bp
  • C to A, chromosome 7 at 34,284,887 bp
  • A to G, chromosome 7 at 41,837,215 bp
  • T to C, chromosome 7 at 43,641,904 bp
  • G to A, chromosome 7 at 46,107,259 bp
  • C to A, chromosome 7 at 85,411,585 bp
  • A to T, chromosome 7 at 90,388,898 bp
  • T to A, chromosome 7 at 103,383,633 bp
  • A to G, chromosome 7 at 133,678,677 bp
  • G to T, chromosome 7 at 142,894,097 bp
  • T to C, chromosome 9 at 65,279,698 bp
  • A to G, chromosome 10 at 7,705,785 bp
  • T to C, chromosome 10 at 128,817,350 bp
  • A to T, chromosome 11 at 36,078,569 bp
  • A to T, chromosome 11 at 59,136,206 bp
  • CCTTCTTCT to CCTTCT, chromosome 11 at 68,213,026 bp
  • T to C, chromosome 11 at 69,186,568 bp
  • A to G, chromosome 11 at 94,570,680 bp
  • T to C, chromosome 11 at 106,159,389 bp
  • A to T, chromosome 11 at 120,983,188 bp
  • C to T, chromosome 12 at 3,401,735 bp
  • A to G, chromosome 13 at 54,539,763 bp
  • T to C, chromosome 13 at 89,704,739 bp
  • A to T, chromosome 13 at 95,513,984 bp
  • A to G, chromosome 13 at 116,308,270 bp
  • T to A, chromosome 14 at 31,142,043 bp
  • C to T, chromosome 14 at 55,651,815 bp
  • T to A, chromosome 14 at 60,802,880 bp
  • A to G, chromosome 15 at 74,853,146 bp
  • T to A, chromosome 15 at 100,195,784 bp
  • A to G, chromosome 16 at 5,077,313 bp
  • A to G, chromosome 16 at 25,866,218 bp
  • A to T, chromosome 16 at 30,540,773 bp
  • C to T, chromosome 17 at 7,351,599 bp
  • G to T, chromosome 17 at 25,153,565 bp
  • G to A, chromosome 17 at 33,241,725 bp
  • A to T, chromosome 17 at 35,470,460 bp
  • T to C, chromosome 17 at 36,039,032 bp
  • A to G, chromosome 17 at 50,607,226 bp
  • T to A, chromosome 18 at 31,447,356 bp
  • T to C, chromosome 18 at 37,012,660 bp
  • A to G, chromosome 18 at 80,322,868 bp
  • T to A, chromosome 19 at 25,505,855 bp
  • C to T, chromosome 19 at 61,175,926 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4870 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042480-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.