Strain Name:
C57BL/6J-MtgxR4878Btlr/Mmmh
Stock Number:
042487-MU
Citation ID:
RRID:MMRRC_042487-MU
Other Names:
R4878 (G1), C57BL/6J-MtgxR4878Btlr
Major Collection:

Gene Information

Nefh
Name: neurofilament, heavy polypeptide
Synonyms: NEFH, NF200, NF-H
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380684
HGNC: HGNC:7737
Homologene: 40755
Wnt3
Name: wingless-type MMTV integration site family, member 3
Synonyms: Wnt-3, Int-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 22415
Homologene: 22527
Utrn
Name: utrophin
Synonyms: G-utrophin, Dmdl, DRP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 22288
VEGA: 10
Homologene: 21398
Cnnm2
Name: cyclin M2
Synonyms: Acdp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 94219
VEGA: 19
HGNC: HGNC:103
Homologene: 9761
Gga3
Name: golgi associated, gamma adaptin ear containing, ARF binding protein 3
Synonyms: C230037M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 260302
Homologene: 121703
Notch3
Name: notch 3
Synonyms: N3, hpbk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 18131
HGNC: HGNC:7883
Homologene: 376
Met
Name: met proto-oncogene
Synonyms: Par4, c-Met, HGF receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 17295
HGNC: HGNC:7029
Homologene: 206
Epb41l4a
Name: erythrocyte membrane protein band 4.1 like 4a
Synonyms: NBL4, Epb4.1l4a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 13824
VEGA: 18
Homologene: 8398
Tfpi
Name: tissue factor pathway inhibitor
Synonyms: A630013F22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 21788
Homologene: 4579
Ubr5
Name: ubiquitin protein ligase E3 component n-recognin 5
Synonyms: 4432411E13Rik, Edd1, Edd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 70790
VEGA: 15
Homologene: 9295
Kif16b
Name: kinesin family member 16B
Synonyms: 8430434E15Rik, N-3 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16558
Homologene: 135708
Agrn
Name: agrin
Synonyms: NMF380, Agrin, nmf380
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11603
HGNC: HGNC:329
Homologene: 27907
Virma
Name: vir like m6A methyltransferase associated
Synonyms: 1110037F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66185
Homologene: 41043
Kif13b
Name: kinesin family member 13B
Synonyms: GAKIN, N-3 kinesin, 5330429L19Rik, C130021D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 16554
VEGA: 14
Homologene: 9073
Rps6kc1
Name: ribosomal protein S6 kinase polypeptide 1
Synonyms: B130003F20Rik, RPK118
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 320119
Homologene: 8244
Mical3
Name: microtubule associated monooxygenase, calponin and LIM domain containing 3
Synonyms: C130040D16Rik, MICAL-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 194401
Homologene: 85288
Dmxl1
Name: Dmx-like 1
Synonyms: C630007L23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240283
HGNC: HGNC:2937
Homologene: 21136
Nup107
Name: nucleoporin 107
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 103468
VEGA: 10
Homologene: 5555
Otud7b
Name: OTU domain containing 7B
Synonyms: 4930463P07Rik, 2900060B22Rik, Za20d1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229603
Homologene: 10624
Piwil1
Name: piwi-like RNA-mediated gene silencing 1
Synonyms: MIWI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 57749
HGNC: HGNC:9007
Homologene: 37963
Sqle
Name: squalene epoxidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 20775
Homologene: 2355
Rad51
Name: RAD51 recombinase
Synonyms: Rad51a, Reca
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19361
HGNC: HGNC:9817
Homologene: 2155
Efemp2
Name: epidermal growth factor-containing fibulin-like extracellular matrix protein 2
Synonyms: MBP1, 0610011K11Rik, Fbln4, fibulin 4, fibulin-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 58859
HGNC: HGNC:3219
Homologene: 32339
Rbm48
Name: RNA binding motif protein 48
Synonyms: C030048B08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 269623
Homologene: 12944
Casc4
Name: cancer susceptibility candidate 4
Synonyms: D130060C09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 319996
Homologene: 16310
Cep295
Name: centrosomal protein 295
Synonyms: LOC382128, 5830418K08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 319675
Homologene: 27936
Ncoa1
Name: nuclear receptor coactivator 1
Synonyms: KAT13A, SRC1, bHLHe74, SRC-1, SRC-a/NCoA-1, steroid receptor coactivator-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 17977
VEGA: 12
HGNC: HGNC:7668
Homologene: 7859
Dnajc6
Name: DnaJ heat shock protein family (Hsp40) member C6
Synonyms: 2810027M23Rik, auxilin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 72685
Homologene: 8865
Klb
Name: klotho beta
Synonyms: betaKlotho
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 83379
Homologene: 12820
Enpep
Name: glutamyl aminopeptidase
Synonyms: Bp-1/6C3, Ly51, APA, 6030431M22Rik, aminopeptidase-A, Ly-51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 13809
HGNC: HGNC:3355
Homologene: 68216
Neb
Name: nebulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Cdh16
Name: cadherin 16
Synonyms: KSP-cadherin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12556
HGNC: HGNC:1755
Homologene: 2997
Aadacl4
Name: arylacetamide deacetylase like 4
Synonyms: Gm13177
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 435815
Homologene: 82530
Gm884
Name: predicted gene 884
Synonyms: LOC380730
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380730
Homologene: 134511
Kif6
Name: kinesin family member 6
Synonyms: D130004B10Rik, D130084M03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 319991
Homologene: 35308
Slc25a39
Name: solute carrier family 25, member 39
Synonyms: D11Ertd333e, 3010027G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68066
Homologene: 69200
Rufy2
Name: RUN and FYVE domain-containing 2
Synonyms: ZFYVE13, 2610111M19Rik, Denn, LZ-FYVE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70432
Homologene: 23064
Mybpc1
Name: myosin binding protein C, slow-type
Synonyms: 8030451F13Rik, Slow-type C-protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 109272
HGNC: HGNC:7549
Homologene: 1846
Pde1a
Name: phosphodiesterase 1A, calmodulin-dependent
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18573
HGNC: HGNC:8774
Homologene: 21043
Atg2a
Name: autophagy related 2A
Synonyms: 1810013C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 329015
Homologene: 86985
Fbln2
Name: fibulin 2
Synonyms: 5730577E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14115
HGNC: HGNC:3601
Homologene: 1514
Adgrg3
Name: adhesion G protein-coupled receptor G3
Synonyms: Pb99, Gpr97, A030001G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 54672
Homologene: 18129
Ppef2
Name: protein phosphatase, EF hand calcium-binding domain 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19023
HGNC: HGNC:9244
Homologene: 55959
Ccndbp1
Name: cyclin D-type binding-protein 1
Synonyms: SSEC-8, stage specific embryonic cDNA-8, GCIP, Maid, DIP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17151
HGNC: HGNC:1587
Homologene: 7826
Emilin1
Name: elastin microfibril interfacer 1
Synonyms: EMILIN-1, gp115, 5830419M17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100952
Homologene: 5117
Daam2
Name: dishevelled associated activator of morphogenesis 2
Synonyms: 2310016D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 76441
VEGA: 17
Homologene: 69186
Msh5
Name: mutS homolog 5
Synonyms: Mut5, G7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17687
HGNC: HGNC:7328
Homologene: 8415
Erlin2
Name: ER lipid raft associated 2
Synonyms: Spfh2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244373
HGNC: HGNC:1356
Homologene: 5193
Olfr412
Name: olfactory receptor 412
Synonyms: MOR127-5P, GA_x6K02T2P1NL-4500587-4501525
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258153
HGNC: HGNC:8183
Homologene: 37634
Rft1
Name: RFT1 homolog
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 328370
Homologene: 5343
Olfr136
Name: olfactory receptor 136
Synonyms: GA_x6K02T2PSCP-2779375-2780313, MOR256-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258803
Homologene: 119758
Zkscan7
Name: zinc finger with KRAB and SCAN domains 7
Synonyms: Zfp167
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 382118
VEGA: 9
Homologene: 83284
Tnk2
Name: tyrosine kinase, non-receptor, 2
Synonyms: Pyk1, P21cdc42Hs kinase, Ack, activated p21cdc42Hs kinase, ACK1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 51789
Homologene: 4224
Rabac1
Name: Rab acceptor 1 (prenylated)
Synonyms: PRA1, 2310040I06Rik, prenylin, Gbpap1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 14470
HGNC: HGNC:9794
Homologene: 38182
Lrif1
Name: ligand dependent nuclear receptor interacting factor 1
Synonyms: 4933421E11Rik, 2010012G17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 321000
Homologene: 10160
Gtpbp6
Name: GTP binding protein 6 (putative)
Synonyms: pgpl, Pgbpll
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 107999
Homologene: 8157
Mios
Name: meiosis regulator for oocyte development
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 252875
Homologene: 10371
Smo
Name: smoothened, frizzled class receptor
Synonyms: E130215L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 319757
Homologene: 4115
Anks6
Name: ankyrin repeat and sterile alpha motif domain containing 6
Synonyms: 2210417J20Rik, Samd6, LOC269533, SamCystin, b2b1801.1Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 75691
Homologene: 19545
Olfr1033
Name: olfactory receptor 1033
Synonyms: GA_x6K02T2Q125-47516301-47517233, MOR199-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258571
Homologene: 138314
Slc17a1
Name: solute carrier family 17 (sodium phosphate), member 1
Synonyms: Npt1, NAPI-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 20504
Homologene: 48324
Pnma2
Name: paraneoplastic antigen MA2
Synonyms: A830049P17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239157
HGNC: HGNC:9159
Homologene: 5249
Hps4
Name: HPS4, biogenesis of lysosomal organelles complex 3 subunit 2
Synonyms: 2010205O06Rik, BLOC-3, C130020P05Rik, Hermansky-Pudlak syndrome 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 192232
Homologene: 11123
Rgs13
Name: regulator of G-protein signaling 13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 246709
HGNC: HGNC:9995
Homologene: 14774
Gm38392
Name: predicted gene, 38392
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Rpl30-ps8
Name: ribosomal protein L30, pseudogene 8
Synonyms: Gm8808
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 667779
VEGA: 12
Ighv1-50
Name: immunoglobulin heavy variable 1-50
Synonyms: Gm16829
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 780929
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 144,171,479 bp
  • A to G, chromosome 1 at 190,800,091 bp
  • T to C, chromosome 2 at 52,219,394 bp
  • A to T, chromosome 2 at 79,878,139 bp
  • A to G, chromosome 2 at 84,452,555 bp
  • A to G, chromosome 2 at 86,041,455 bp
  • T to C, chromosome 2 at 119,120,492 bp
  • T to A, chromosome 2 at 121,014,691 bp
  • C to G, chromosome 2 at 121,867,234 bp
  • T to C, chromosome 2 at 142,848,003 bp
  • A to C, chromosome 3 at 88,247,453 bp
  • T to A, chromosome 3 at 96,136,510 bp
  • A to T, chromosome 3 at 106,735,640 bp
  • A to T, chromosome 3 at 129,276,771 bp
  • T to A, chromosome 4 at 11,544,971 bp
  • C to T, chromosome 4 at 47,030,795 bp
  • T to C, chromosome 4 at 101,599,034 bp
  • C to A, chromosome 4 at 144,613,845 bp
  • A to T, chromosome 4 at 156,170,845 bp
  • A to T, chromosome 5 at 3,591,853 bp
  • A to G, chromosome 5 at 30,917,066 bp
  • A to T, chromosome 5 at 65,348,490 bp
  • A to C, chromosome 5 at 92,228,740 bp
  • A to G, chromosome 5 at 110,105,067 bp
  • C to T, chromosome 5 at 110,107,311 bp
  • T to C, chromosome 5 at 112,375,368 bp
  • G to T, chromosome 5 at 128,740,981 bp
  • A to G, chromosome 6 at 8,215,094 bp
  • A to G, chromosome 6 at 17,549,059 bp
  • A to G, chromosome 6 at 29,753,571 bp
  • T to C, chromosome 6 at 91,256,995 bp
  • A to T, chromosome 6 at 120,969,387 bp
  • T to A, chromosome 7 at 24,969,967 bp
  • T to A, chromosome 8 at 27,027,166 bp
  • A to T, chromosome 8 at 95,035,086 bp
  • A to T, chromosome 8 at 104,618,064 bp
  • A to T, chromosome 9 at 15,334,956 bp
  • G to T, chromosome 9 at 122,890,800 bp
  • T to A, chromosome 10 at 12,727,758 bp
  • A to T, chromosome 10 at 63,002,211 bp
  • T to C, chromosome 10 at 88,551,430 bp
  • A to T, chromosome 10 at 117,751,418 bp
  • A to G, chromosome 11 at 4,941,333 bp
  • T to C, chromosome 11 at 74,364,848 bp
  • G to A, chromosome 11 at 102,403,675 bp
  • A to G, chromosome 11 at 103,617,891 bp
  • G to T, chromosome 11 at 103,808,205 bp
  • A to T, chromosome 11 at 115,591,321 bp
  • C to T, chromosome 12 at 4,275,004 bp
  • T to A, chromosome 12 at 99,047,519 bp
  • T to C, chromosome 12 at 115,119,947 bp
  • T to C, chromosome 13 at 23,880,654 bp
  • C to T, chromosome 14 at 30,677,804 bp
  • T to C, chromosome 14 at 64,806,154 bp
  • G to A, chromosome 14 at 66,917,054 bp
  • A to T, chromosome 15 at 38,006,564 bp
  • A to G, chromosome 15 at 59,316,085 bp
  • A to G, chromosome 16 at 32,679,630 bp
  • C to T, chromosome 17 at 32,147,085 bp
  • G to A, chromosome 17 at 35,038,456 bp
  • T to G, chromosome 17 at 38,335,627 bp
  • C to A, chromosome 17 at 49,460,710 bp
  • T to A, chromosome 17 at 49,722,267 bp
  • A to G, chromosome 18 at 33,798,572 bp
  • T to A, chromosome 18 at 49,851,476 bp
  • A to T, chromosome 19 at 5,480,761 bp
  • A to T, chromosome 19 at 6,250,244 bp
  • C to T, chromosome 19 at 46,859,083 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4878 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042487-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.