Strain Name:
C57BL/6J-MtgxR4904Btlr/Mmmh
Stock Number:
042507-MU
Citation ID:
RRID:MMRRC_042507-MU
Other Names:
R4904 (G1), C57BL/6J-MtgxR4904Btlr
Major Collection:

Gene Information

Hfe
Name: homeostatic iron regulator
Synonyms: MR2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 15216
HGNC: HGNC:4886
Homologene: 88330
Dicer1
Name: dicer 1, ribonuclease type III
Synonyms: D12Ertd7e, 1110006F08Rik, Dicer1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 192119
VEGA: 12
Homologene: 13251
Sod1
Name: superoxide dismutase 1, soluble
Synonyms: Ipo1, Cu/Zn-SOD, Sod-1, Cu(2+)-Zn2+ superoxide dismutase, SODC, Ipo-1, B430204E11Rik, CuZnSOD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 20655
VEGA: 16
Homologene: 392
Itgb8
Name: integrin beta 8
Synonyms: 4832412O06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 320910
HGNC: HGNC:6163
Homologene: 18567
Ptch1
Name: patched 1
Synonyms: Patched 1, wig, A230106A15Rik, Ptc, Ptc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 19206
HGNC: HGNC:9585
Homologene: 223
Sez6
Name: seizure related gene 6
Synonyms: D11Bhm177e, sez-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20370
Homologene: 10948
Dst
Name: dystonin
Synonyms: ah, athetoid, A830042E19Rik, nmf203, Macf2, BPAG1, 2310001O04Rik, BPAG1-n, bullous pemphigoid antigen 1, bullous pemphigoid antigen 1, Bpag, Bpag1, nmf339
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Med26
Name: mediator complex subunit 26
Synonyms: Crsp7, 5730493L18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 70625
HGNC: HGNC:2376
Homologene: 68417
Rilpl1
Name: Rab interacting lysosomal protein-like 1
Synonyms: GOSPEL, 2900002H16Rik, 6330559I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 75695
Homologene: 15619
Arhgap21
Name: Rho GTPase activating protein 21
Synonyms: ARHGAP10, 5530401C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71435
Homologene: 10822
Kntc1
Name: kinetochore associated 1
Synonyms: jgl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 208628
Homologene: 32227
Pds5a
Name: PDS5 cohesin associated factor A
Synonyms: 9030416H16Rik, E230024D05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71521
Homologene: 22877
Herc2
Name: HECT and RLD domain containing E3 ubiquitin protein ligase 2
Synonyms: D7H15F37S1, jdf2, D7H15F32S1, D15F32S1h, rjs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 15204
HGNC: HGNC:4868
Homologene: 3430
Ankfy1
Name: ankyrin repeat and FYVE domain containing 1
Synonyms: Ankhzn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11736
Homologene: 9491
Slc9a8
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 8
Synonyms: NHE8, 1200006P13Rik, 6430709P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 77031
Homologene: 75041
Slc45a4
Name: solute carrier family 45, member 4
Synonyms: 9330175B01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 106068
Homologene: 69908
Syn3
Name: synapsin III
Synonyms: Synapsin IIIa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 27204
Homologene: 68320
Adgrb2
Name: adhesion G protein-coupled receptor B2
Synonyms: Bai2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230775
HGNC: HGNC:944
Homologene: 1288
Vps13d
Name: vacuolar protein sorting 13D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230895
Homologene: 15583
Xpot
Name: exportin, tRNA (nuclear export receptor for tRNAs)
Synonyms: EXPORTIN-T, 1110004L07Rik, C79645
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 73192
VEGA: 10
Homologene: 38291
Dtl
Name: denticleless E3 ubiquitin protein ligase
Synonyms: 5730564G15Rik, 2810047L02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 76843
Homologene: 32313
Gprc5c
Name: G protein-coupled receptor, family C, group 5, member C
Synonyms: 3200002M13Rik, 1110028I06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 70355
Homologene: 11099
Mpp3
Name: membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
Synonyms: Dlgh3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13384
HGNC: HGNC:7221
Homologene: 31065
Def8
Name: differentially expressed in FDCP 8
Synonyms: D8Ertd713e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 23854
Homologene: 14279
Dcbld1
Name: discoidin, CUB and LCCL domain containing 1
Synonyms: 4631413K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 66686
Homologene: 12010
Trim33
Name: tripartite motif-containing 33
Synonyms: Tif1g, ectodermin, 8030451N04Rik, Ecto
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 94093
Homologene: 9296
Jag1
Name: jagged 1
Synonyms: Gsfabe2, Ozz, ABE2, Headturner, Htu, Serrate-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16449
HGNC: HGNC:6188
Homologene: 180
Ebf1
Name: early B cell factor 1
Synonyms: Olf-1, O/E-1, Olf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13591
HGNC: HGNC:3126
Homologene: 7297
Hspa1a
Name: heat shock protein 1A
Synonyms: Hsp68, Hsp70a1, Hsp70-3, Hsp70.3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 193740
Homologene: 74294
Aqp9
Name: aquaporin 9
Synonyms: 1700020I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 64008
HGNC: HGNC:643
Homologene: 41405
Tspear
Name: thrombospondin type laminin G domain and EAR repeats
Synonyms: ORF65, C330046G03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 252974
HGNC: HGNC:1268
Homologene: 36972
Afap1l1
Name: actin filament associated protein 1-like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 106877
Homologene: 18728
Col6a3
Name: collagen, type VI, alpha 3
Synonyms: Col6a-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12835
HGNC: HGNC:2213
Homologene: 37917
Pak5
Name: p21 (RAC1) activated kinase 5
Synonyms: 2900083L08Rik, Pak7, Pak5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241656
Homologene: 22211
Myoc
Name: myocilin
Synonyms: GLC1A, TIGR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 17926
HGNC: HGNC:7610
Homologene: 220
Hrg
Name: histidine-rich glycoprotein
Synonyms: D18020, D16JH2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 94175
HGNC: HGNC:5181
Homologene: 137650
Rpgrip1
Name: retinitis pigmentosa GTPase regulator interacting protein 1
Synonyms: nmf247, 4930401L23Rik, 4930505G06Rik, A930002K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 77945
Homologene: 10679
Duox1
Name: dual oxidase 1
Synonyms: NOXEF1, THOX1, LNOX1, 9930101G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99439
HGNC: HGNC:3062
Homologene: 68136
Sema3a
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
Synonyms: semaphorin III, collapsin-1, SemD, sema III, Semad
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20346
Homologene: 31358
Rflnb
Name: refilin B
Synonyms: 1500005K14Rik, Fam101b, cfm, RefilinB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 76566
Homologene: 18809
Golgb1
Name: golgi autoantigen, golgin subfamily b, macrogolgin 1
Synonyms: Gm6840, F730017E11Rik, C130074L01Rik, Giantin, 6330407A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224139
HGNC: HGNC:4429
Homologene: 68401
Ly86
Name: lymphocyte antigen 86
Synonyms: MD-1, MD1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17084
VEGA: 13
Homologene: 48274
Shank1
Name: SH3 and multiple ankyrin repeat domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243961
Homologene: 22949
Tcaf3
Name: TRPM8 channel-associated factor 3
Synonyms: Fam115e, Eapa2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 403088
Homologene: 74374
Gm6327
Name: predicted gene 6327
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Zfp955a
Name: zinc finger protein 955A
Synonyms: AI842447
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 77652
VEGA: 17
Homologene: 104925
Tmem236
Name: transmembrane protein 236
Synonyms: Fam23a, 2010003H20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 625286
Homologene: 46598
Pde6a
Name: phosphodiesterase 6A, cGMP-specific, rod, alpha
Synonyms: Pdea
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225600
HGNC: HGNC:8785
Homologene: 380
Pcdhb12
Name: protocadherin beta 12
Synonyms: PcdhbL, Pcdh3, Pcdhb5F
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93883
Homologene: 87126
Polrmt
Name: polymerase (RNA) mitochondrial (DNA directed)
Synonyms: 1110018N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216151
HGNC: HGNC:9200
Homologene: 37996
Plch1
Name: phospholipase C, eta 1
Synonyms: PLCeta1, Plcl3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 269437
Homologene: 88833
Olfr111
Name: olfactory receptor 111
Synonyms: MOR249-1P, GA_x6K02T2PSCP-1989071-1990024
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 545205
Homologene: 73968
Sult1b1
Name: sulfotransferase family 1B, member 1
Synonyms: Dopa/tyrosine sulfotransferase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56362
Homologene: 69169
Cfap61
Name: cilia and flagella associated protein 61
Synonyms: 4930529M08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 78774
Tll1
Name: tolloid-like
Synonyms: b2b2476Clo, Tll-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 21892
Homologene: 49202
AW822073
Name: expressed sequence AW822073
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 100504180
Homologene: 134545
Olfr1418
Name: olfactory receptor 1418
Synonyms: GA_x6K02T2RE5P-2207258-2206302, MOR266-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258227
Homologene: 79372
Taar8c
Name: trace amine-associated receptor 8C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 494546
Homologene: 77586
Pigq
Name: phosphatidylinositol glycan anchor biosynthesis, class Q
Synonyms: Gpi1, Gpih, Gpi1h, Gpi1p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14755
Homologene: 31228
Kcnq5
Name: potassium voltage-gated channel, subfamily Q, member 5
Synonyms: D1Mgi1, 9230107O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226922
HGNC: HGNC:6299
Homologene: 28270
Cybb
Name: cytochrome b-245, beta polypeptide
Synonyms: gp91phox, Nox2, Cgd, gp91phox
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 13058
HGNC: HGNC:2578
Homologene: 68054
Olfr574
Name: olfactory receptor 574
Synonyms: GA_x6K02T2PBJ9-5659738-5660748, MOR14-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258357
Homologene: 27137
Zdhhc3
Name: zinc finger, DHHC domain containing 3
Synonyms: 2210017C02Rik, 1110020O22Rik, 1810006O10Rik, Zfp373, GODZ
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 69035
Homologene: 9582
Gtf2a1l
Name: general transcription factor IIA, 1-like
Synonyms: Alf, Gtf2a1lf, 1700011N16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 71828
Homologene: 86732
Tbx20
Name: T-box 20
Synonyms: 9430010M06Rik, Tbx12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 57246
VEGA: 9
Homologene: 32476
Dnah7c
Name: dynein, axonemal, heavy chain 7C
Synonyms: Dnahc7c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 100101919
Homologene: 41287
Coq8a
Name: coenzyme Q8A
Synonyms: 4632432J16Rik, Cabc1, Adck3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 67426
Homologene: 11345
Arrdc1
Name: arrestin domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 215705
Homologene: 34835
Armc7
Name: armadillo repeat containing 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 276905
Homologene: 11603
Uros
Name: uroporphyrinogen III synthase
Synonyms: URO-synthase, Uros3, hydroxymethylbilane hydrolyase (cyclizing), uroporphyrinogen-III synthase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22276
Homologene: 37296
Nlrp1c-ps
Name: NLR family, pyrin domain containing 1C, pseudogene
Synonyms: Nalp1c, OTTMUSG00000006090
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 627984
Gm6625
Name: predicted gene 6625
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 625801
Gm44501
Name: predicted readthrough transcript, 44501
Synonyms: Esp6Esp5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 102577428
VEGA: 17
Homologene: 136357
Pcdhga2
Name: protocadherin gamma subfamily A, 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93710
HGNC: HGNC:8700
Homologene: 69262
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 21,424,100 bp
  • A to T, chromosome 1 at 34,169,798 bp
  • T to C, chromosome 1 at 46,654,039 bp
  • A to T, chromosome 1 at 90,801,442 bp
  • G to A, chromosome 1 at 162,639,425 bp
  • C to T, chromosome 1 at 180,178,603 bp
  • A to T, chromosome 1 at 191,568,345 bp
  • T to A, chromosome 2 at 14,195,992 bp
  • A to G, chromosome 2 at 20,850,061 bp
  • C to A, chromosome 2 at 24,926,664 bp
  • T to A, chromosome 2 at 122,320,864 bp
  • A to T, chromosome 2 at 136,083,347 bp
  • A to G, chromosome 2 at 137,087,142 bp
  • A to G, chromosome 2 at 146,153,849 bp
  • A to G, chromosome 2 at 167,471,396 bp
  • T to C, chromosome 3 at 63,698,975 bp
  • T to C, chromosome 3 at 103,331,647 bp
  • T to G, chromosome 4 at 130,012,539 bp
  • T to C, chromosome 4 at 145,155,445 bp
  • A to C, chromosome 5 at 13,581,098 bp
  • A to T, chromosome 5 at 65,620,658 bp
  • T to C, chromosome 5 at 87,535,053 bp
  • T to C, chromosome 5 at 123,778,333 bp
  • C to A, chromosome 5 at 124,514,744 bp
  • C to A, chromosome 6 at 42,593,997 bp
  • G to T, chromosome 7 at 44,334,040 bp
  • T to C, chromosome 7 at 56,157,486 bp
  • A to G, chromosome 7 at 102,949,065 bp
  • T to C, chromosome 7 at 133,700,851 bp
  • A to T, chromosome 8 at 64,070,199 bp
  • A to T, chromosome 8 at 72,496,847 bp
  • T to C, chromosome 8 at 89,146,751 bp
  • A to G, chromosome 8 at 123,461,480 bp
  • T to C, chromosome 9 at 24,758,833 bp
  • A to C, chromosome 9 at 71,162,403 bp
  • A to T, chromosome 9 at 123,100,387 bp
  • C to T, chromosome 10 at 24,101,249 bp
  • C to T, chromosome 10 at 52,319,970 bp
  • T to A, chromosome 10 at 58,223,487 bp
  • T to A, chromosome 10 at 77,869,655 bp
  • A to G, chromosome 10 at 79,746,551 bp
  • T to G, chromosome 10 at 86,467,086 bp
  • C to T, chromosome 10 at 121,617,178 bp
  • T to C, chromosome 11 at 44,869,169 bp
  • A to G, chromosome 11 at 71,242,628 bp
  • C to A, chromosome 11 at 72,752,105 bp
  • A to T, chromosome 11 at 76,022,138 bp
  • A to G, chromosome 11 at 77,975,254 bp
  • T to C, chromosome 11 at 102,000,587 bp
  • G to T, chromosome 11 at 114,864,267 bp
  • A to G, chromosome 11 at 115,488,974 bp
  • C to T, chromosome 12 at 104,713,066 bp
  • T to C, chromosome 12 at 119,170,871 bp
  • A to T, chromosome 13 at 23,708,054 bp
  • G to T, chromosome 13 at 37,415,520 bp
  • A to C, chromosome 13 at 63,523,004 bp
  • T to C, chromosome 14 at 52,121,087 bp
  • A to T, chromosome 14 at 52,160,129 bp
  • G to A, chromosome 15 at 73,586,842 bp
  • G to A, chromosome 16 at 12,760,145 bp
  • A to G, chromosome 16 at 22,951,250 bp
  • A to T, chromosome 16 at 36,893,386 bp
  • T to A, chromosome 16 at 90,222,844 bp
  • A to G, chromosome 17 at 25,931,060 bp
  • A to T, chromosome 17 at 33,242,188 bp
  • T to C, chromosome 17 at 34,970,451 bp
  • A to G, chromosome 17 at 37,530,631 bp
  • A to T, chromosome 17 at 40,578,993 bp
  • G to A, chromosome 17 at 88,690,043 bp
  • T to C, chromosome 18 at 37,437,856 bp
  • A to G, chromosome 18 at 37,669,879 bp
  • A to T, chromosome 18 at 61,265,034 bp
  • A to G, chromosome 18 at 61,738,715 bp
  • C to T, chromosome 19 at 11,855,867 bp
  • C to G, chromosome X at 9,450,750 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4904 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042507-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.