Strain Name:
C57BL/6J-MtgxR4938Btlr/Mmmh
Stock Number:
042537-MU
Citation ID:
RRID:MMRRC_042537-MU
Other Names:
R4938 (G1), C57BL/6J-MtgxR4938Btlr
Major Collection:

Gene Information

Fgg
Name: fibrinogen gamma chain
Synonyms: gamma-fibrinogen, 3010002H13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99571
HGNC: HGNC:3694
Homologene: 429
Tyrp1
Name: tyrosinase-related protein 1
Synonyms: TRP-1, isa, Tyrp, TRP1, Oca3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 22178
Homologene: 464
Plekhj1
Name: pleckstrin homology domain containing, family J member 1
Synonyms: 9530063M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 78670
VEGA: 10
Homologene: 11389
Grm1
Name: glutamate receptor, metabotropic 1
Synonyms: rcw, nmf373, mGluR1, Grm1, Gprc1a, 4930455H15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 14816
HGNC: HGNC:4593
Homologene: 649
Ngf
Name: nerve growth factor
Synonyms: Ngfb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 18049
HGNC: HGNC:7808
Homologene: 1876
Cyp19a1
Name: cytochrome P450, family 19, subfamily a, polypeptide 1
Synonyms: aromatase, ArKO, Cyp19, Int5, Ar, Int-5, p450arom
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 13075
VEGA: 9
HGNC: HGNC:2594
Homologene: 30955
Cacna1g
Name: calcium channel, voltage-dependent, T type, alpha 1G subunit
Synonyms: a1G, Cav3.1d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 12291
HGNC: HGNC:1394
Homologene: 22544
Cep55
Name: centrosomal protein 55
Synonyms: 1200008O12Rik, 2700032M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 74107
VEGA: 19
HGNC: HGNC:1161
Homologene: 10019
Trmo
Name: tRNA methyltransferase O
Synonyms: 5830415F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 74753
Homologene: 32316
Lrp2
Name: low density lipoprotein receptor-related protein 2
Synonyms: D230004K18Rik, b2b1625.2Clo, Gp330, Megalin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 14725
HGNC: HGNC:6694
Homologene: 20952
Kcnq2
Name: potassium voltage-gated channel, subfamily Q, member 2
Synonyms: KQT2, Nmf134
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16536
HGNC: HGNC:6296
Homologene: 26174
Zfp532
Name: zinc finger protein 532
Synonyms: C530030I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 328977
Homologene: 138627
Pdxdc1
Name: pyridoxal-dependent decarboxylase domain containing 1
Synonyms: 2210010A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 94184
Homologene: 22858
Mllt6
Name: myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6
Synonyms: Af17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 246198
HGNC: HGNC:7138
Homologene: 31347
Vasp
Name: vasodilator-stimulated phosphoprotein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22323
Homologene: 7592
Fry
Name: FRY microtubule binding protein
Synonyms: 9330186A19Rik, cg003
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 320365
Homologene: 113770
Nsrp1
Name: nuclear speckle regulatory protein 1
Synonyms: NSpr70, Ccdc55
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237859
Homologene: 134095
Etl4
Name: enhancer trap locus 4
Synonyms: Sickle tail, 6620402G01Rik, 9430077C05Rik, Etl-4, Skt, E330027G05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 208618
Homologene: 10477
Mettl3
Name: methyltransferase like 3
Synonyms: M6A, Spo8, 2310024F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 56335
Homologene: 10501
Nup214
Name: nucleoporin 214
Synonyms: D2H9S46E, CAN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227720
HGNC: HGNC:8064
Homologene: 38008
Taf1c
Name: TATA-box binding protein associated factor, RNA polymerase I, C
Synonyms: mTAFI95
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 21341
Homologene: 21163
Mmp27
Name: matrix metallopeptidase 27
Synonyms: LOC234911
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 234911
Homologene: 23345
Notch1
Name: notch 1
Synonyms: lin-12, Tan1, N1, Motch A, 9930111A19Rik, Mis6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18128
HGNC: HGNC:7881
Homologene: 32049
Slc20a2
Name: solute carrier family 20, member 2
Synonyms: Ram1, Ram-1, PiT-2, MolPit2, Pit-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 20516
Homologene: 68531
Stmn2
Name: stathmin-like 2
Synonyms: Scgn10, SCG10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 20257
Homologene: 5102
Sec13
Name: SEC13 homolog, nuclear pore and COPII coat complex component
Synonyms: Sec13r, 1110003H02Rik, Sec13l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 110379
Homologene: 6479
Riok3
Name: RIO kinase 3
Synonyms: D18Ertd331e, Sudd, E130306C24Rik, 1200013N13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 66878
VEGA: 18
Homologene: 2843
Zfp296
Name: zinc finger protein 296
Synonyms: 2210018A16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 63872
Homologene: 11185
Ncapg
Name: non-SMC condensin I complex, subunit G
Synonyms: 5730507H05Rik, MFT.M05.13, Hcapg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 54392
Homologene: 44071
Papln
Name: papilin, proteoglycan-like sulfated glycoprotein
Synonyms: E030033C16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 170721
Homologene: 71541
Lrrc4c
Name: leucine rich repeat containing 4C
Synonyms: netrin g1 ligand, 6430556C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241568
Homologene: 18696
Pnp
Name: purine-nucleoside phosphorylase
Synonyms: Pnp1, Pnp, Np, Np-2, Np-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 18950
HGNC: HGNC:7892
Homologene: 227
Dnajc6
Name: DnaJ heat shock protein family (Hsp40) member C6
Synonyms: 2810027M23Rik, auxilin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 72685
Homologene: 8865
Zfyve28
Name: zinc finger, FYVE domain containing 28
Synonyms: 9630058O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231125
Homologene: 15119
Atp6v0a4
Name: ATPase, H+ transporting, lysosomal V0 subunit A4
Synonyms: V-ATPase alpha 4, Atp6n1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 140494
HGNC: HGNC:866
Homologene: 39904
Col12a1
Name: collagen, type XII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 12816
HGNC: HGNC:2188
Homologene: 3217
Glp2r
Name: glucagon-like peptide 2 receptor
Synonyms: GLP-2, 9530092J08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 93896
HGNC: HGNC:4325
Homologene: 3132
Mdh1b
Name: malate dehydrogenase 1B, NAD (soluble)
Synonyms: 1700124B08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 76668
Homologene: 57110
Kcnab1
Name: potassium voltage-gated channel, shaker-related subfamily, beta member 1
Synonyms: Kvbeta1.1, Akr8a8, mKv(beta)1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 16497
HGNC: HGNC:6228
Homologene: 56491
Fras1
Name: Fraser extracellular matrix complex subunit 1
Synonyms: E130113P14Rik, bl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231470
Homologene: 23516
Tnxb
Name: tenascin XB
Synonyms: Tnx, TN-MHC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 81877
Homologene: 49589
Vmn1r231
Name: vomeronasal 1 receptor 231
Synonyms: V1re7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 171230
HGNC: null
Homologene: null
Thsd7a
Name: thrombospondin, type I, domain containing 7A
Synonyms: LOC330267
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 330267
Homologene: 46582
Cdr2l
Name: cerebellar degeneration-related protein 2-like
Synonyms: D030068L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237988
Homologene: 35390
Prss37
Name: protease, serine 37
Synonyms: 1700016G05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 67690
Homologene: 12174
Irf2bpl
Name: interferon regulatory factor 2 binding protein-like
Synonyms: 6430527G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 238330
VEGA: 12
Homologene: 11555
Zfp563
Name: zinc finger protein 563
Synonyms: Zfp413, zinc finger protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 240068
Homologene: 77346
Olfr1444
Name: olfactory receptor 1444
Synonyms: MOR202-4, GA_x6K02T2RE5P-3191201-3192160
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258697
Homologene: 64906
Insyn2b
Name: inhibitory synaptic factor family member 2B
Synonyms: Fam196b, Gm6041
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 574403
VEGA: 11
Homologene: 107175
Polrmt
Name: polymerase (RNA) mitochondrial (DNA directed)
Synonyms: 1110018N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216151
HGNC: HGNC:9200
Homologene: 37996
E330013P04Rik
Name: RIKEN cDNA E330013P04 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 107376
HGNC: null
Homologene: null
Zfp647
Name: zinc finger protein 647
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239546
VEGA: 15
Homologene: 27805
Cfhr2
Name: complement factor H-related 2
Synonyms: FHR-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 545366
HGNC: null
Homologene: 134349
Mstn
Name: myostatin
Synonyms: Gdf8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 17700
HGNC: HGNC:4223
Homologene: 3850
Zfp964
Name: zinc finger protein 964
Synonyms: Gm7187
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 636741
HGNC: null
Homologene: 130114
Hspa14
Name: heat shock protein 14
Synonyms: NST-1, Hsp70-4, HSP70L1, 70kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 50497
Homologene: 74307
Ptx4
Name: pentraxin 4
Synonyms: 1110018H23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 68509
VEGA: 17
Homologene: 19179
Fitm1
Name: fat storage-inducing transmembrane protein 1
Synonyms: 1110028A07Rik, Fit1, Cg10671
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 68680
Homologene: 41695
Npdc1
Name: neural proliferation, differentiation and control 1
Synonyms: NPDC-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18146
HGNC: HGNC:7899
Homologene: 32050
Polr3gl
Name: polymerase (RNA) III (DNA directed) polypeptide G like
Synonyms: 2010003I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 69870
Homologene: 41712
Ifnlr1
Name: interferon lambda receptor 1
Synonyms: Il28ra, CRF2-12, IFNLR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242700
Homologene: 52086
Galnt17
Name: polypeptide N-acetylgalactosaminyltransferase 17
Synonyms: Galnt19, Wbscr17, E330012B09Rik, Gcap8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 212996
Homologene: 49707
Zfp703
Name: zinc finger protein 703
Synonyms: Zeppo1, Csmn1, End2, 1110032O19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 353310
Homologene: 81391
Hoxd13
Name: homeobox D13
Synonyms: Hox-4.8, spdh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 15433
HGNC: HGNC:5136
Homologene: 20147
Qsox1
Name: quiescin Q6 sulfhydryl oxidase 1
Synonyms: b2b2673Clo, Qscn6, 1300003H02Rik, QSOX
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 104009
HGNC: HGNC:9756
Homologene: 37690
Smad9
Name: SMAD family member 9
Synonyms: Madh9, SMAD8B, SMAD8A, MADH6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 55994
HGNC: HGNC:6774
Homologene: 21198
Olfr902
Name: olfactory receptor 902
Synonyms: GA_x6K02T2PVTD-32141623-32142552, MOR169-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258798
VEGA: 9
HGNC: null
Homologene: null
Fam107b
Name: family with sequence similarity 107, member B
Synonyms: 3110001A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 66540
Homologene: 75316
Ighv5-9
Name: immunoglobulin heavy variable 5-9
Synonyms: Gm16949
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 544896
HGNC: null
Homologene: null
Arl14ep
Name: ADP-ribosylation factor-like 14 effector protein
Synonyms: 4930448O08Rik, 2700007P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 212772
Homologene: 17546
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 53,066,423 bp
  • T to C, chromosome 1 at 63,711,504 bp
  • C to T, chromosome 1 at 139,813,527 bp
  • T to C, chromosome 1 at 155,779,668 bp
  • A to T, chromosome 2 at 3,491,609 bp
  • A to T, chromosome 2 at 3,772,870 bp
  • A to G, chromosome 2 at 20,798,649 bp
  • A to G, chromosome 2 at 25,399,417 bp
  • G to A, chromosome 2 at 26,474,124 bp
  • C to A, chromosome 2 at 31,983,159 bp
  • G to A, chromosome 2 at 69,472,368 bp
  • A to G, chromosome 2 at 74,668,683 bp
  • A to T, chromosome 2 at 97,629,301 bp
  • G to T, chromosome 2 at 106,969,318 bp
  • A to G, chromosome 2 at 181,086,973 bp
  • A to G, chromosome 3 at 8,545,732 bp
  • G to A, chromosome 3 at 54,789,230 bp
  • A to G, chromosome 3 at 65,295,284 bp
  • A to T, chromosome 3 at 83,012,868 bp
  • T to C, chromosome 3 at 96,579,892 bp
  • C to T, chromosome 3 at 102,520,474 bp
  • G to T, chromosome 4 at 46,382,388 bp
  • C to T, chromosome 4 at 80,840,646 bp
  • T to G, chromosome 4 at 101,636,813 bp
  • A to G, chromosome 4 at 135,705,282 bp
  • A to C, chromosome 5 at 34,233,354 bp
  • A to G, chromosome 5 at 45,671,209 bp
  • A to G, chromosome 5 at 96,776,724 bp
  • A to T, chromosome 5 at 131,306,399 bp
  • C to T, chromosome 5 at 150,477,989 bp
  • T to A, chromosome 6 at 12,330,992 bp
  • T to A, chromosome 6 at 38,078,814 bp
  • A to G, chromosome 6 at 40,514,983 bp
  • A to G, chromosome 6 at 113,735,192 bp
  • T to C, chromosome 7 at 19,257,717 bp
  • A to G, chromosome 7 at 19,584,778 bp
  • T to C, chromosome 8 at 22,561,205 bp
  • C to A, chromosome 8 at 26,979,773 bp
  • A to G, chromosome 8 at 69,664,108 bp
  • A to G, chromosome 8 at 119,598,798 bp
  • G to T, chromosome 9 at 7,578,982 bp
  • T to A, chromosome 9 at 38,449,383 bp
  • T to A, chromosome 9 at 54,173,363 bp
  • C to A, chromosome 9 at 79,700,350 bp
  • C to T, chromosome 9 at 79,700,351 bp
  • C to T, chromosome 10 at 10,936,513 bp
  • A to G, chromosome 10 at 79,746,551 bp
  • A to T, chromosome 10 at 80,797,775 bp
  • G to A, chromosome 11 at 34,402,231 bp
  • G to T, chromosome 11 at 67,757,593 bp
  • T to C, chromosome 11 at 77,045,744 bp
  • G to A, chromosome 11 at 94,415,818 bp
  • A to G, chromosome 11 at 97,678,407 bp
  • A to G, chromosome 11 at 115,393,825 bp
  • C to T, chromosome 12 at 83,782,903 bp
  • A to G, chromosome 12 at 86,882,118 bp
  • A to G, chromosome 12 at 113,661,962 bp
  • A to G, chromosome 14 at 50,963,568 bp
  • A to T, chromosome 14 at 52,299,727 bp
  • A to C, chromosome 14 at 55,576,619 bp
  • TGCACG to TGCACGCACG, chromosome 15 at 76,911,044 bp
  • A to G, chromosome 16 at 13,876,069 bp
  • T to C, chromosome 17 at 20,890,351 bp
  • C to T, chromosome 17 at 25,123,165 bp
  • G to A, chromosome 17 at 33,105,709 bp
  • A to G, chromosome 17 at 34,713,632 bp
  • T to A, chromosome 18 at 12,155,243 bp
  • T to C, chromosome 18 at 65,623,766 bp
  • T to A, chromosome 19 at 12,862,552 bp
  • A to G, chromosome 19 at 38,069,916 bp
  • C to G, chromosome 19 at 60,162,021 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4938 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042537-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.