Strain Name:
C57BL/6J-MtgxR4944Btlr/Mmmh
Stock Number:
042541-MU
Citation ID:
RRID:MMRRC_042541-MU
Other Names:
R4944 (G1), C57BL/6J-MtgxR4944Btlr
Major Collection:

Gene Information

Plxnd1
Name: plexin D1
Synonyms: 6230425C21Rik, b2b553Clo, b2b1863Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 67784
HGNC: HGNC:9107
Homologene: 22866
Armc9
Name: armadillo repeat containing 9
Synonyms: 5730415N24Rik, 3830422A13Rik, 4831423D23Rik, 4930438O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 78795
Homologene: 11847
Ints1
Name: integrator complex subunit 1
Synonyms: 1110015K06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 68510
Homologene: 53111
Cabin1
Name: calcineurin binding protein 1
Synonyms: Ppp3in, Cain, A330070M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 104248
VEGA: 10
Homologene: 49307
Slx4ip
Name: SLX4 interacting protein
Synonyms: 2410004I22Rik, 2210009G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74243
Homologene: 49913
Top2a
Name: topoisomerase (DNA) II alpha
Synonyms: DNA Topoisomerase II alpha, Top-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 21973
Homologene: 830
Mon2
Name: MON2 homolog, regulator of endosome to Golgi trafficking
Synonyms: SF21, 2610528O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67074
VEGA: 10
Homologene: 44309
Zgrf1
Name: zinc finger, GRF-type containing 1
Synonyms: 4930422G04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 71643
Homologene: 34708
Kat14
Name: lysine acetyltransferase 14
Synonyms: 2510008M08Rik, D2Ertd473e, D2Wsu131e, ATAC2, Csrp2bp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228714
Homologene: 10745
Tg
Name: thyroglobulin
Synonyms: Tgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 21819
Homologene: 2430
Psmg1
Name: proteasome (prosome, macropain) assembly chaperone 1
Synonyms: Dscr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 56088
HGNC: HGNC:3043
Homologene: 2759
Gp5
Name: glycoprotein 5 (platelet)
Synonyms: GPV, GP V
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 14729
VEGA: 16
HGNC: HGNC:4443
Homologene: 74523
Gprin3
Name: GPRIN family member 3
Synonyms: C030038J10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243385
Homologene: 52334
Utp25
Name: UTP25 small subunit processome component
Synonyms: AA408296, Diexf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 215193
Homologene: 6170
Angptl7
Name: angiopoietin-like 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 654812
Homologene: 133923
Tcea3
Name: transcription elongation factor A (SII), 3
Synonyms: S-II, SII-K1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 21401
Homologene: 20684
Gpn3
Name: GPN-loop GTPase 3
Synonyms: A930018B01Rik, D5Ertd708e, Atpbd1c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 68080
Homologene: 6487
Lamtor1
Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
Synonyms: p18, 2400001E08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 66508
Homologene: 9909
Szt2
Name: SZT2 subunit of KICSTOR complex
Synonyms: seaizure threshold 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230676
Homologene: 49413
Tm4sf20
Name: transmembrane 4 L six family member 20
Synonyms: 1810018L02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 66261
Homologene: 11722
Dnajc13
Name: DnaJ heat shock protein family (Hsp40) member C13
Synonyms: Rme8, LOC382100, D030002L11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235567
Homologene: 13574
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 94109
Homologene: 69536
Pla2g4e
Name: phospholipase A2, group IVE
Synonyms: 2310026J01Rik, Pla2epsilon
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329502
Homologene: 65339
Ndst3
Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
Synonyms: 4930511P15Rik, 4921531K01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 83398
HGNC: HGNC:7682
Homologene: 3513
Abcb4
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 4
Synonyms: mdr-2, Mdr2, Pgy-2, Pgy2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18670
HGNC: HGNC:45
Homologene: 136368
Arhgap30
Name: Rho GTPase activating protein 30
Synonyms: 6030405P05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226652
Homologene: 18766
Ptprd
Name: protein tyrosine phosphatase, receptor type, D
Synonyms: 3000002J10Rik, B230219D21Rik, 1110002J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 19266
HGNC: HGNC:9668
Pkhd1
Name: polycystic kidney and hepatic disease 1
Synonyms: tigmin, FPC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241035
HGNC: HGNC:9016
Homologene: 16336
Stradb
Name: STE20-related kinase adaptor beta
Synonyms: PRO1038, D1Ucla2, Als2cr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227154
Homologene: 10237
Slc1a5
Name: solute carrier family 1 (neutral amino acid transporter), member 5
Synonyms: ASCT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20514
Homologene: 21155
Col11a2
Name: collagen, type XI, alpha 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12815
HGNC: HGNC:2187
Homologene: 22547
Clcn3
Name: chloride channel, voltage-sensitive 3
Synonyms: Clc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12725
HGNC: HGNC:2021
Homologene: 20435
Tecta
Name: tectorin alpha
Synonyms: [a]-tectorin, Tctna
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 21683
Homologene: 3955
Usp40
Name: ubiquitin specific peptidase 40
Synonyms: B230215L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227334
Homologene: 32400
Galnt11
Name: polypeptide N-acetylgalactosaminyltransferase 11
Synonyms: E430002F06Rik, A430075I06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231050
Homologene: 11126
Col5a2
Name: collagen, type V, alpha 2
Synonyms: 1110014L14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12832
HGNC: HGNC:2210
Homologene: 20119
Hfm1
Name: HFM1, ATP-dependent DNA helicase homolog
Synonyms: LOC381663, A330009G12Rik, Sec63d1, Mer3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 330149
Homologene: 87103
Usp29
Name: ubiquitin specific peptidase 29
Synonyms: Ocat
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 57775
Homologene: 49641
Cntn1
Name: contactin 1
Synonyms: CNTN, F3cam, usl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12805
HGNC: HGNC:2171
Homologene: 7274
Gm884
Name: predicted gene 884
Synonyms: LOC380730
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380730
Homologene: 134511
Taar6
Name: trace amine-associated receptor 6
Synonyms: LOC215855
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215855
Homologene: 27874
Slc5a3
Name: solute carrier family 5 (inositol transporters), member 3
Synonyms: Smit1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 53881
Homologene: 31412
Cdh2
Name: cadherin 2
Synonyms: N-cadherin, Ncad, N-CAD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 12558
HGNC: HGNC:1759
Homologene: 20424
Oas1h
Name: 2'-5' oligoadenylate synthetase 1H
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 246729
HGNC: HGNC:8086
Homologene: 77345
Atxn1
Name: ataxin 1
Synonyms: Atx1, Sca1, 2900016G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 20238
VEGA: 13
Homologene: 281
Mog
Name: myelin oligodendrocyte glycoprotein
Synonyms: B230317G11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17441
HGNC: HGNC:7197
Homologene: 111009
Rgs22
Name: regulator of G-protein signalling 22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 626596
Homologene: 75047
Ovgp1
Name: oviductal glycoprotein 1
Synonyms: MOGP, muc9, mucin 9, oviductin, Chit5, OGP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12659
HGNC: HGNC:8524
Homologene: 74442
Smtn
Name: smoothelin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 29856
Homologene: 8482
Scg2
Name: secretogranin II
Synonyms: SgII, Chgc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20254
Homologene: 2591
Vmn1r121
Name: vomeronasal 1 receptor 121
Synonyms: Gm8533
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 667240
Homologene: 104166
Nacad
Name: NAC alpha domain containing
Synonyms: mKIAA0363
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192950
Homologene: 135717
Dhcr7
Name: 7-dehydrocholesterol reductase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13360
HGNC: HGNC:2860
Homologene: 1042
Lrrc24
Name: leucine rich repeat containing 24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 378937
Homologene: 86785
Vmn2r49
Name: vomeronasal 2, receptor 49
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 625605
Homologene: 113703
Catsperd
Name: cation channel sperm associated auxiliary subunit delta
Synonyms: 4933402B14Rik, Gm6095, 4921529N20Rik, Tmem146
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 106757
VEGA: 17
Homologene: 51896
Sema4c
Name: sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
Synonyms: M-Sema F, Semaf, Semacl1, Semai, Semacl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20353
Homologene: 23047
Prrxl1
Name: paired related homeobox protein-like 1
Synonyms: Drg11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 107751
Rgs7bp
Name: regulator of G-protein signalling 7 binding protein
Synonyms: A930030I01Rik, R7bp, D13Bwg1146e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 52882
VEGA: 13
Homologene: 78705
Ube2r2
Name: ubiquitin-conjugating enzyme E2R 2
Synonyms: Cdc34b, Ubc3b, 1200003M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67615
Homologene: 3210
Gm10083
Name: predicted gene 10083
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 102639847
Josd2
Name: Josephin domain containing 2
Synonyms: 1110007C05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 66124
Homologene: 26696
Mtx1
Name: metaxin 1
Synonyms: Gcap6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 17827
HGNC: HGNC:7504
Homologene: 37623
Nkx6-2
Name: NK6 homeobox 2
Synonyms: Gtx, Nkx6.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 14912
Homologene: 18580
Folr2
Name: folate receptor 2 (fetal)
Synonyms: FBP2, Folbp2, FR-P3, Folbp-2, Folbp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 14276
HGNC: HGNC:3793
Homologene: 627
Olfr936
Name: olfactory receptor 936
Synonyms: GA_x6K02T2PVTD-32743332-32742397, MOR171-37, EG628171
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 100503486
VEGA: 9
Rrp7a
Name: ribosomal RNA processing 7 homolog A
Synonyms: 1110014J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 74778
Homologene: 41060
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 20,288,205 bp
  • C to A, chromosome 1 at 36,550,311 bp
  • T to G, chromosome 1 at 45,376,695 bp
  • T to C, chromosome 1 at 58,980,440 bp
  • T to A, chromosome 1 at 79,436,476 bp
  • T to A, chromosome 1 at 82,768,363 bp
  • T to A, chromosome 1 at 86,274,534 bp
  • T to C, chromosome 1 at 87,952,355 bp
  • A to T, chromosome 1 at 171,402,254 bp
  • A to T, chromosome 1 at 193,114,954 bp
  • T to C, chromosome 2 at 120,171,237 bp
  • T to A, chromosome 2 at 137,046,767 bp
  • C to A, chromosome 2 at 144,375,953 bp
  • T to C, chromosome 3 at 89,213,898 bp
  • T to C, chromosome 3 at 105,979,953 bp
  • T to C, chromosome 3 at 123,607,027 bp
  • C to T, chromosome 3 at 127,561,868 bp
  • A to G, chromosome 4 at 41,190,742 bp
  • G to A, chromosome 4 at 76,128,899 bp
  • T to C, chromosome 4 at 118,388,669 bp
  • A to T, chromosome 4 at 136,268,093 bp
  • C to G, chromosome 4 at 148,500,077 bp
  • G to A, chromosome 5 at 8,934,327 bp
  • T to C, chromosome 5 at 25,265,338 bp
  • T to C, chromosome 5 at 106,874,213 bp
  • A to G, chromosome 5 at 120,862,783 bp
  • T to C, chromosome 5 at 122,382,240 bp
  • T to C, chromosome 5 at 139,758,092 bp
  • T to C, chromosome 6 at 59,354,659 bp
  • A to G, chromosome 6 at 115,955,765 bp
  • T to C, chromosome 7 at 6,961,928 bp
  • T to A, chromosome 7 at 9,989,032 bp
  • T to A, chromosome 7 at 16,797,743 bp
  • C to T, chromosome 7 at 21,097,613 bp
  • T to C, chromosome 7 at 44,471,168 bp
  • T to C, chromosome 7 at 101,840,290 bp
  • C to T, chromosome 7 at 101,909,764 bp
  • T to C, chromosome 7 at 139,581,570 bp
  • T to A, chromosome 7 at 143,837,791 bp
  • C to T, chromosome 8 at 15,998,772 bp
  • A to G, chromosome 8 at 47,413,265 bp
  • G to A, chromosome 8 at 60,929,179 bp
  • A to G, chromosome 9 at 39,046,862 bp
  • A to G, chromosome 9 at 42,330,277 bp
  • C to T, chromosome 9 at 104,167,387 bp
  • T to C, chromosome 10 at 23,984,715 bp
  • C to T, chromosome 10 at 75,721,363 bp
  • A to G, chromosome 10 at 75,739,421 bp
  • A to G, chromosome 10 at 123,038,459 bp
  • C to T, chromosome 11 at 3,522,916 bp
  • T to C, chromosome 11 at 6,598,507 bp
  • T to C, chromosome 11 at 98,997,850 bp
  • T to C, chromosome 11 at 103,613,460 bp
  • T to G, chromosome 13 at 45,566,931 bp
  • T to C, chromosome 13 at 104,951,564 bp
  • G to T, chromosome 14 at 32,608,249 bp
  • T to C, chromosome 15 at 36,025,942 bp
  • G to A, chromosome 15 at 66,764,337 bp
  • A to G, chromosome 15 at 76,718,346 bp
  • T to C, chromosome 15 at 83,119,809 bp
  • C to A, chromosome 15 at 92,228,668 bp
  • G to A, chromosome 16 at 30,309,508 bp
  • A to G, chromosome 16 at 92,078,683 bp
  • A to T, chromosome 16 at 95,989,612 bp
  • T to C, chromosome 17 at 34,042,190 bp
  • T to C, chromosome 17 at 37,020,541 bp
  • T to C, chromosome 17 at 56,662,744 bp
  • A to G, chromosome 18 at 16,650,409 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4944 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
042541-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.