Strain Name:
C57BL/6J-MtgxR4971Btlr/Mmmh
Stock Number:
042566-MU
Citation ID:
RRID:MMRRC_042566-MU
Other Names:
R4971 (G1), C57BL/6J-MtgxR4971Btlr
Major Collection:

Gene Information

Ing4
Name: inhibitor of growth family, member 4
Synonyms: D6Xrf92, p29ING4, D6Wsu147e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 28019
Homologene: 22952
Map4k5
Name: mitogen-activated protein kinase kinase kinase kinase 5
Synonyms: KHS, MAPKKKK5, 4432415E19Rik, GCKR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 399510
HGNC: HGNC:6867
Homologene: 38199
Kmt2c
Name: lysine (K)-specific methyltransferase 2C
Synonyms: E330008K23Rik, HALR, Mll3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231051
Homologene: 46480
Nos1
Name: nitric oxide synthase 1, neuronal
Synonyms: nNOS, Nos-1, bNOS, NO, 2310005C01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 18125
HGNC: HGNC:7872
Homologene: 37327
Frem2
Name: Fras1 related extracellular matrix protein 2
Synonyms: b2b1562Clo, my, 6030440P17Rik, ne, 8430406N05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 242022
Homologene: 18454
Txndc2
Name: thioredoxin domain containing 2 (spermatozoa)
Synonyms: Sptrx-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 213272
VEGA: 17
Homologene: 41856
Jade1
Name: jade family PHD finger 1
Synonyms: D530048A03Rik, Phf17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 269424
Homologene: 18162
Map3k4
Name: mitogen-activated protein kinase kinase kinase 4
Synonyms: D17Rp17e, MAPKKK4, D17Rp17, MTK1, Tas, RP17, Mekk4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 26407
VEGA: 17
HGNC: HGNC:6856
Homologene: 31346
Prdx1
Name: peroxiredoxin 1
Synonyms: Paga, Prx I, TDX2, thioredoxin dependent peroxide reductase 2, Trx dependent peroxide reductase 2, osteoblast specific factor 3, macrophase stress protein 22kDa, macrophage 23kDa stress protein, Tdpx2, MSP23, PrxI, PAG, OSF-3, prx1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 18477
HGNC: HGNC:9352
Homologene: 99789
Rab1a
Name: RAB1A, member RAS oncogene family
Synonyms: Rab-1, Gtbp, Rab1, ras-related YPT1 protein, Ypt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 19324
HGNC: HGNC:9758
Homologene: 36154
Nf1
Name: neurofibromin 1
Synonyms: neurofibromin, Nf-1, Mhdadsk9, Dsk9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 18015
HGNC: HGNC:7765
Homologene: 226
Kif13b
Name: kinesin family member 13B
Synonyms: 5330429L19Rik, N-3 kinesin, GAKIN, C130021D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 16554
VEGA: 14
Homologene: 9073
Resf1
Name: retroelement silencing factor 1
Synonyms: 2810474O19Rik, GET
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 67246
Homologene: 19251
Top2a
Name: topoisomerase (DNA) II alpha
Synonyms: Top-2, DNA Topoisomerase II alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 21973
Homologene: 830
Cnot1
Name: CCR4-NOT transcription complex, subunit 1
Synonyms: 6030411K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234594
HGNC: HGNC:7877
Homologene: 9453
Mdn1
Name: midasin AAA ATPase 1
Synonyms: LOC213784, D4Abb1e, 4833432B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100019
Homologene: 39689
Cyb5r4
Name: cytochrome b5 reductase 4
Synonyms: b5/b5r, B5+B5R, Ncb5or, 2810034J18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 266690
Homologene: 69207
Oga
Name: O-GlcNAcase
Synonyms: 2810009A20Rik, Hy5, 4833427O07Rik, 5830447M11Rik, Mgea5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 76055
VEGA: 19
HGNC: HGNC:7056
Homologene: 8154
Nr3c1
Name: nuclear receptor subfamily 3, group C, member 1
Synonyms: Grl1, GR, glucocorticoid receptor, Grl-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 14815
HGNC: HGNC:7978
Homologene: 30960
Rhot1
Name: ras homolog family member T1
Synonyms: Arht1, 2210403N23Rik, FLJ11040, C430039G08Rik, Miro1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 59040
Homologene: 56803
Eif2ak1
Name: eukaryotic translation initiation factor 2 alpha kinase 1
Synonyms: Hri
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 15467
Homologene: 8290
Cul7
Name: cullin 7
Synonyms: p185, p193, 2510004L20Rik, C230011P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 66515
Homologene: 56683
Adamtsl1
Name: ADAMTS-like 1
Synonyms: 6720426B09Rik, 5930437A14Rik, punctin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 77739
Homologene: 64642
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: 4432416O06Rik, DHC2, b2b414Clo, Dnchc2, m407Asp, m152Asp, D030010H02Rik, D330044F14Rik, DHC1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Myo19
Name: myosin XIX
Synonyms: Myohd1, 1110055A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 66196
Homologene: 49819
Gak
Name: cyclin G associated kinase
Synonyms: D130045N16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231580
HGNC: HGNC:4113
Homologene: 3846
Rbp3
Name: retinol binding protein 3, interstitial
Synonyms: Rbp-3, Irbp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 19661
VEGA: 14
HGNC: HGNC:9921
Homologene: 9261
Muc5ac
Name: mucin 5, subtypes A and C, tracheobronchial/gastric
Synonyms: MGM, 2210005L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 17833
HGNC: HGNC:7515
Homologene: 137237
Mroh7
Name: maestro heat-like repeat family member 7
Synonyms: Gm1027, LOC381538, Heatr8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 381538
Homologene: 19633
Zscan10
Name: zinc finger and SCAN domain containing 10
Synonyms: Zfp206, Zscan10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 332221
Homologene: 13122
F5
Name: coagulation factor V
Synonyms: Cf5, Cf-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 14067
HGNC: HGNC:3542
Homologene: 104
Abcg4
Name: ATP binding cassette subfamily G member 4
Synonyms: 6430517O04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 192663
Homologene: 75179
Stat4
Name: signal transducer and activator of transcription 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 20849
Homologene: 20679
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241516
Homologene: 110349
Cdkl3
Name: cyclin-dependent kinase-like 3
Synonyms: B230379H01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 213084
Homologene: 49467
Sema3d
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
Synonyms: 4631426B19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 108151
Homologene: 23664
Abca9
Name: ATP-binding cassette, sub-family A (ABC1), member 9
Synonyms: D630040K07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217262
HGNC: HGNC:39
Homologene: 33332
A2ml1
Name: alpha-2-macroglobulin like 1
Synonyms: BC048546, Ovos2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232400
Homologene: 45969
Slfn10-ps
Name: schlafen 10, pseudogene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237887
Ctse
Name: cathepsin E
Synonyms: A430072O03Rik, C920004C08Rik, CE, CatE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 13034
HGNC: HGNC:2530
Homologene: 37551
Tbc1d2b
Name: TBC1 domain family, member 2B
Synonyms: 1810061M12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 67016
Homologene: 56694
Slc13a3
Name: solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
Synonyms: SDCT2, NaDC3, NaDC-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 114644
Homologene: 11266
Abca2
Name: ATP-binding cassette, sub-family A (ABC1), member 2
Synonyms: D2H0S1474E, Abc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 11305
HGNC: HGNC:32
Homologene: 55590
Gzmc
Name: granzyme C
Synonyms: Ctla-5, Ctla5, CCP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 14940
VEGA: 14
Homologene: 105844
Mup5
Name: major urinary protein 5
Synonyms: Mup V
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 17844
Homologene: 74304
Olfr1212
Name: olfactory receptor 1212
Synonyms: MOR233-20, GA_x6K02T2Q125-50437014-50437949, MOR233-17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258241
Homologene: 66154
Colq
Name: collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 102639719
HGNC: HGNC:2226
Gm15448
Name: predicted gene 15448
Synonyms: ENSMUSG00000074419
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 100041146
HGNC: HGNC:6607
Homologene: 134028
Ikbke
Name: inhibitor of kappaB kinase epsilon
Synonyms: IKKepsilon, IKK-i
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 56489
Homologene: 23168
Irs3
Name: insulin receptor substrate 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 16369
HGNC: HGNC:6127
Homologene: 84788
Abcd2
Name: ATP-binding cassette, sub-family D (ALD), member 2
Synonyms: adrenoleukodystrophy related, ALDL1, ABC39, ALDR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 26874
VEGA: 15
HGNC: HGNC:66
Homologene: 55873
Actl9
Name: actin-like 9
Synonyms: 1700029I08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 69481
Homologene: 77642
Cd3eap
Name: CD3E antigen, epsilon polypeptide associated protein
Synonyms: PAF49, 2610103M17Rik, Ase1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 70333
Homologene: 17107
Anks6
Name: ankyrin repeat and sterile alpha motif domain containing 6
Synonyms: Samd6, 2210417J20Rik, LOC269533, SamCystin, b2b1801.1Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 75691
Homologene: 19545
Rbfox1
Name: RNA binding protein, fox-1 homolog (C. elegans) 1
Synonyms: FOX1, HRNBP1, A2bp, A2bp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 268859
VEGA: 16
Homologene: 69339
Zfp456
Name: zinc finger protein 456
Synonyms: Rslcan-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 408065
Homologene: 110878
Pdlim2
Name: PDZ and LIM domain 2
Synonyms: 4732462F18Rik, mystique, SLIM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 213019
Homologene: 11006
Setbp1
Name: SET binding protein 1
Synonyms: Seb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 240427
Homologene: 9192
Runx1t1
Name: RUNX1 translocation partner 1
Synonyms: Cbfa2t1h, MTG8, ETO
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 12395
HGNC: HGNC:1535
Homologene: 3801
Ptma-ps1
Name: prothymosin alpha, pseudogene 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 622446
Eif1-ps1
Name: eukaryotic translation initiation factor 1, pseudogene 1
Synonyms: Gm10713
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 100040439
VEGA: 14
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 52,106,949 bp
  • GCC to G, chromosome 1 at 131,275,267 bp
  • A to T, chromosome 1 at 131,664,392 bp
  • A to T, chromosome 1 at 164,194,186 bp
  • T to C, chromosome 2 at 25,441,994 bp
  • C to T, chromosome 2 at 82,985,878 bp
  • A to T, chromosome 2 at 88,958,519 bp
  • A to G, chromosome 2 at 165,448,699 bp
  • T to A, chromosome 3 at 41,601,401 bp
  • T to C, chromosome 3 at 53,539,183 bp
  • C to T, chromosome 4 at 13,837,978 bp
  • T to C, chromosome 4 at 32,739,827 bp
  • C to T, chromosome 4 at 47,030,795 bp
  • T to A, chromosome 4 at 61,833,060 bp
  • T to C, chromosome 4 at 86,336,931 bp
  • A to G, chromosome 4 at 106,691,552 bp
  • T to C, chromosome 4 at 116,691,931 bp
  • C to T, chromosome 5 at 12,463,241 bp
  • A to G, chromosome 5 at 25,310,872 bp
  • T to C, chromosome 5 at 108,596,806 bp
  • T to C, chromosome 5 at 117,943,834 bp
  • T to A, chromosome 5 at 137,644,492 bp
  • A to G, chromosome 5 at 143,882,168 bp
  • A to T, chromosome 6 at 125,043,998 bp
  • A to T, chromosome 6 at 128,547,227 bp
  • T to C, chromosome 6 at 149,325,599 bp
  • T to A, chromosome 7 at 3,822,806 bp
  • T to C, chromosome 7 at 19,357,562 bp
  • T to G, chromosome 7 at 24,064,096 bp
  • T to C, chromosome 7 at 141,816,278 bp
  • A to G, chromosome 8 at 95,721,626 bp
  • A to T, chromosome 9 at 7,131,949 bp
  • A to C, chromosome 9 at 44,278,056 bp
  • G to T, chromosome 9 at 87,057,171 bp
  • A to T, chromosome 9 at 90,218,870 bp
  • T to C, chromosome 11 at 20,218,935 bp
  • T to C, chromosome 11 at 52,011,168 bp
  • T to A, chromosome 11 at 79,444,643 bp
  • T to A, chromosome 11 at 80,233,474 bp
  • C to T, chromosome 11 at 83,030,381 bp
  • T to A, chromosome 11 at 84,892,197 bp
  • T to C, chromosome 11 at 98,993,841 bp
  • A to T, chromosome 11 at 110,152,048 bp
  • C to T, chromosome 12 at 69,852,719 bp
  • T to C, chromosome 13 at 67,366,876 bp
  • T to C, chromosome 14 at 31,545,077 bp
  • T to A, chromosome 14 at 33,954,470 bp
  • C to T, chromosome 14 at 40,006,469 bp
  • G to T, chromosome 14 at 56,232,369 bp
  • T to A, chromosome 14 at 64,757,562 bp
  • A to G, chromosome 14 at 70,167,759 bp
  • T to C, chromosome 15 at 91,163,110 bp
  • C to T, chromosome 16 at 7,294,088 bp
  • A to G, chromosome 17 at 12,249,495 bp
  • A to G, chromosome 17 at 23,607,173 bp
  • T to A, chromosome 17 at 33,433,908 bp
  • G to T, chromosome 17 at 46,659,119 bp
  • A to T, chromosome 17 at 65,638,854 bp
  • T to C, chromosome 18 at 39,486,877 bp
  • A to G, chromosome 18 at 78,858,167 bp
  • C to A, chromosome 19 at 45,770,046 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4971 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042566-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.