Strain Name:
C57BL/6J-MtgxR4994Btlr/Mmmh
Stock Number:
042588-MU
Citation ID:
RRID:MMRRC_042588-MU
Other Names:
R4994 (G1), C57BL/6J-MtgxR4994Btlr
Major Collection:

Gene Information

Acadm
Name: acyl-Coenzyme A dehydrogenase, medium chain
Synonyms: MCAD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 11364
HGNC: HGNC:89
Homologene: 3
Sort1
Name: sortilin 1
Synonyms: Ntr3, neurotensin receptor 3, 2900053A11Rik, sortilin, Ntsr3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 20661
Homologene: 136097
Blm
Name: Bloom syndrome, RecQ like helicase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 12144
HGNC: HGNC:1058
Homologene: 47902
Csnk1e
Name: casein kinase 1, epsilon
Synonyms: CKI epsilon, tau, CK1epsilon, CKIepsilon, KC1epsilon
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 27373
HGNC: HGNC:2453
Homologene: 121695
Maco1
Name: macoilin 1
Synonyms: Tmem57, 9230118A01Rik, C61, 1110007C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 66146
Homologene: 14449
Trnt1
Name: tRNA nucleotidyl transferase, CCA-adding, 1
Synonyms: 2410043H24Rik, CGI-47, 2610044E04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 70047
Homologene: 9333
Mtif3
Name: mitochondrial translational initiation factor 3
Synonyms: 2810012L14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 76366
Homologene: 49927
Cdk7
Name: cyclin-dependent kinase 7
Synonyms: Crk4, CRK4 PK (CDC2-related-kinase-4 protein kinase), Cdkn7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 12572
VEGA: 13
HGNC: HGNC:1778
Homologene: 1363
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Phr1, C130061D10Rik, Pam
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 105689
Homologene: 9005
Arhgap21
Name: Rho GTPase activating protein 21
Synonyms: ARHGAP10, 5530401C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 71435
Homologene: 10822
Fbrsl1
Name: fibrosin-like 1
Synonyms: LOC381668, Gm29766, 2410025L10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 381668
Homologene: 45966
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: apollon, D630005A10Rik, A430040A19Rik, Bruce, A430032G04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 12211
Homologene: 7248
Lgr4
Name: leucine-rich repeat-containing G protein-coupled receptor 4
Synonyms: A930009A08Rik, A330106J01Rik, Gpr48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 107515
Homologene: 10226
Rsf1
Name: remodeling and spacing factor 1
Synonyms: XAP8, p325, 4832420A03Rik, C030033M12Rik, Hbxap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233532
Homologene: 41142
Nop56
Name: NOP56 ribonucleoprotein
Synonyms: Nol5a, 56kDa with KKE/D repeat, NOP56, 2310044F10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 67134
Homologene: 4660
Marf1
Name: meiosis regulator and mRNA stability 1
Synonyms: 4921513D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 223989
VEGA: 16
Homologene: 40967
Pigr
Name: polymeric immunoglobulin receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18703
HGNC: HGNC:8968
Homologene: 1984
Echdc2
Name: enoyl Coenzyme A hydratase domain containing 2
Synonyms: 1300017C12Rik, 2610009M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 52430
Homologene: 23088
Clec14a
Name: C-type lectin domain family 14, member a
Synonyms: 1200003C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 66864
VEGA: 12
Homologene: 12047
Ubxn7
Name: UBX domain protein 7
Synonyms: Ubxd7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 224111
VEGA: 16
Homologene: 45585
Slc39a6
Name: solute carrier family 39 (metal ion transporter), member 6
Synonyms: Zip6, Ermelin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 106957
Homologene: 8199
Taf4b
Name: TATA-box binding protein associated factor 4b
Synonyms: 105kDa, 2610524B04Rik, TAFII105, Taf2c2, 4932409F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 72504
VEGA: 18
Homologene: 28266
Peak1
Name: pseudopodium-enriched atypical kinase 1
Synonyms: 1110049L02Rik, C230081A13Rik, NKF3 kinase family member
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244895
Homologene: 18259
Cd209a
Name: CD209a antigen
Synonyms: Dcsign, DC-SIGN, SIGNR5, CIRE, DC-SIGN1, CD209
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 170786
Homologene: 129771
Six3
Name: sine oculis-related homeobox 3
Synonyms: E130112M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 20473
Homologene: 3947
Fbxo33
Name: F-box protein 33
Synonyms: 5730501N20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 70611
Homologene: 16501
Hmcn2
Name: hemicentin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 665700
Homologene: 90772
Dennd5b
Name: DENN/MADD domain containing 5B
Synonyms: 9330160C06Rik, D030011O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 320560
Homologene: 44911
Abcb4
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 4
Synonyms: mdr-2, Mdr2, Pgy2, Pgy-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 18670
HGNC: HGNC:45
Homologene: 136368
Trappc11
Name: trafficking protein particle complex 11
Synonyms: D030016E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 320714
Homologene: 11076
Zfp605
Name: zinc finger protein 605
Synonyms: A830023I12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 675812
Homologene: 52335
Zhx2
Name: zinc fingers and homeoboxes 2
Synonyms: Afr-1, Afr1, Raf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 387609
Homologene: 8968
Stab2
Name: stabilin 2
Synonyms: STAB-2, FEEL-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 192188
Homologene: 23022
Cyb5d1
Name: cytochrome b5 domain containing 1
Synonyms: LOC327951
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 327951
Homologene: 15945
Cma1
Name: chymase 1, mast cell
Synonyms: Mcp-5, Mcp5, MMCP-5, Mcpt5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 17228
VEGA: 14
HGNC: HGNC:2097
Homologene: 55606
Kif6
Name: kinesin family member 6
Synonyms: D130004B10Rik, D130084M03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 319991
Homologene: 35308
Stk33
Name: serine/threonine kinase 33
Synonyms: 4921505G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 117229
Homologene: 75307
Unc13a
Name: unc-13 homolog A
Synonyms: Munc13-1, 2410078G03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 382018
Homologene: 11279
Lingo4
Name: leucine rich repeat and Ig domain containing 4
Synonyms: A530050P17Rik, Lrrn6d, LERN4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 320747
Homologene: 18563
Kif14
Name: kinesin family member 14
Synonyms: N-3 kinesin, D1Ertd367e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 381293
Homologene: 8916
Gm13089
Name: predicted gene 13089
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 277667
Col5a1
Name: collagen, type V, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 12831
HGNC: HGNC:2209
Homologene: 55434
Esm1
Name: endothelial cell-specific molecule 1
Synonyms: 0610042H23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 71690
HGNC: HGNC:3466
Homologene: 5107
Dipk2a
Name: divergent protein kinase domain 2A
Synonyms: 1190002N15Rik, GoPro49
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 68861
Homologene: 18315
Tpte
Name: transmembrane phosphatase with tensin homology
Synonyms: Pten2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234129
Homologene: 50411
Serpina3f
Name: serine (or cysteine) peptidase inhibitor, clade A, member 3F
Synonyms: 2A1, antitrypsin, alpha-1 antiproteinasin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 238393
HGNC: HGNC:16
Homologene: 115927
Il3ra
Name: interleukin 3 receptor, alpha chain
Synonyms: SUT-1, IL-3 receptor alpha chain, CD123
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 16188
VEGA: 14
HGNC: HGNC:6012
Homologene: 48088
Wdhd1
Name: WD repeat and HMG-box DNA binding protein 1
Synonyms: D630024B06Rik, AND-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 218973
Homologene: 56019
Ppfia3
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
Synonyms: 2410127E16Rik, Liprin-alpha3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 76787
HGNC: HGNC:9247
Homologene: 37833
Nrd1
Name: nardilysin, N-arginine dibasic convertase, NRD convertase 1
Synonyms: NRD-C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230598
HGNC: HGNC:7995
Homologene: 68260
Hspa4l
Name: heat shock protein 4 like
Synonyms: 94kDa, APG-1, Osp94
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 18415
Homologene: 22610
Cntnap3
Name: contactin associated protein-like 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 238680
VEGA: 13
Homologene: 129602
Timd4
Name: T cell immunoglobulin and mucin domain containing 4
Synonyms: TIM-4, Tim4, B430010N18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 276891
Homologene: 51381
Plekhg3
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 3
Synonyms: MGC40768
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 263406
VEGA: 12
Homologene: 77478
Ankrd6
Name: ankyrin repeat domain 6
Synonyms: diversin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 140577
Homologene: 8967
Slc40a1
Name: solute carrier family 40 (iron-regulated transporter), member 1
Synonyms: IREG1, Pcm, Dusg, Slc11a3, metal transporting protein 1, MTP1, Ol5, ferroportin1, FPN1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 53945
Homologene: 40959
Fbh1
Name: F-box DNA helicase 1
Synonyms: Fbxo18, Fbx18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 50755
Homologene: 9272
Tspyl5
Name: testis-specific protein, Y-encoded-like 5
Synonyms: E130308C19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239364
VEGA: 15
Homologene: 14134
Dzank1
Name: double zinc ribbon and ankyrin repeat domains 1
Synonyms: 2810039F03Rik, 6330439K17Rik, Ankrd64
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241688
Homologene: 10037
4930505A04Rik
Name: RIKEN cDNA 4930505A04 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 75087
Homologene: 18988
Sestd1
Name: SEC14 and spectrin domains 1
Synonyms: 1500031J16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228071
Homologene: 45505
1700030K09Rik
Name: RIKEN cDNA 1700030K09 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 72254
Homologene: 12975
Olfr715
Name: olfactory receptor 715
Synonyms: MOR260-1, GA_x6K02T2PBJ9-9479517-9478573
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258776
HGNC: HGNC:8244
Homologene: 81541
Terf2
Name: telomeric repeat binding factor 2
Synonyms: TRF2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 21750
Homologene: 4133
Fbxo6
Name: F-box protein 6
Synonyms: Fbs2, FBG2, Fbx6b, Fbxo6b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 50762
Homologene: 9274
Aldh1b1
Name: aldehyde dehydrogenase 1 family, member B1
Synonyms: 2700007F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 72535
HGNC: HGNC:407
Homologene: 115470
Adrb3
Name: adrenergic receptor, beta 3
Synonyms: Beta-3 AR, beta 3-AR, beta3-adrenergic receptor, Adrb-3, Beta-3 adrenoceptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 11556
HGNC: HGNC:288
Homologene: 37250
Trabd2b
Name: TraB domain containing 2B
Synonyms: Hkat, Gm12824
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 666048
Homologene: 85034
Gm17093
Name: predicted gene 17093
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
Homologene: 128452
Irx5
Name: Iroquois homeobox 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 54352
Homologene: 38105
Slc35f6
Name: solute carrier family 35, member F6
Synonyms: p40, 5730478O19Rik, Tango9, 4930471M23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 74919
Homologene: 9896
Drp2
Name: dystrophin related protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 13497
HGNC: HGNC:3032
Homologene: 55620
Mtfmt
Name: mitochondrial methionyl-tRNA formyltransferase
Synonyms: 2310020P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 69606
Homologene: 12320
Rnase2b
Name: ribonuclease, RNase A family, 2B (liver, eosinophil-derived neurotoxin)
Synonyms: Ear5, murine ribonuclease 5, mR5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 54159
VEGA: 14
Homologene: 121614
Lag3
Name: lymphocyte-activation gene 3
Synonyms: CD223, LAG-3, Ly66
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16768
HGNC: HGNC:6476
Homologene: 1719
Lkaaear1
Name: LKAAEAR motif containing 1 (IKAAEAR murine motif)
Synonyms: LOC277496, 4930526D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 277496
Homologene: 52380
Erich2os
Name: glutamate rich 2, opposite strand
Synonyms: Gm16292
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
Vmn1r127
Name: vomeronasal 1 receptor 127
Synonyms: Gm6239
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 621561
Homologene: 104166
BC043934
Name: cDNA sequence BC043934
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 45,909,664 bp
  • G to A, chromosome 1 at 130,841,817 bp
  • G to T, chromosome 1 at 136,482,959 bp
  • T to A, chromosome 2 at 11,764,230 bp
  • T to A, chromosome 2 at 20,849,890 bp
  • A to C, chromosome 2 at 28,032,739 bp
  • T to C, chromosome 2 at 31,458,055 bp
  • T to C, chromosome 2 at 70,509,132 bp
  • G to A, chromosome 2 at 77,198,908 bp
  • A to G, chromosome 2 at 110,011,938 bp
  • C to A, chromosome 2 at 130,277,264 bp
  • T to G, chromosome 2 at 144,522,566 bp
  • C to A, chromosome 2 at 181,697,583 bp
  • C to A, chromosome 3 at 40,745,649 bp
  • A to G, chromosome 3 at 94,402,541 bp
  • T to A, chromosome 3 at 94,403,001 bp
  • G to A, chromosome 3 at 108,328,069 bp
  • C to T, chromosome 3 at 153,929,584 bp
  • A to G, chromosome 4 at 32,860,387 bp
  • A to G, chromosome 4 at 45,803,128 bp
  • A to G, chromosome 4 at 108,165,628 bp
  • A to G, chromosome 4 at 109,046,612 bp
  • T to C, chromosome 4 at 114,406,855 bp
  • A to G, chromosome 4 at 134,828,299 bp
  • T to A, chromosome 4 at 143,698,369 bp
  • A to T, chromosome 4 at 148,149,491 bp
  • A to G, chromosome 5 at 8,928,524 bp
  • A to G, chromosome 5 at 30,648,083 bp
  • A to G, chromosome 5 at 110,127,486 bp
  • A to G, chromosome 5 at 110,447,951 bp
  • G to A, chromosome 5 at 146,956,788 bp
  • C to T, chromosome 6 at 106,778,892 bp
  • T to A, chromosome 6 at 124,904,453 bp
  • T to C, chromosome 6 at 149,041,500 bp
  • A to T, chromosome 7 at 21,319,018 bp
  • T to C, chromosome 7 at 45,341,118 bp
  • A to C, chromosome 7 at 80,458,825 bp
  • CGGCGGC to CGGCGGCCGCGGCGGC, chromosome 7 at 97,579,923 bp
  • T to C, chromosome 7 at 107,129,064 bp
  • T to A, chromosome 7 at 109,340,398 bp
  • T to C, chromosome 8 at 3,747,713 bp
  • T to C, chromosome 8 at 22,318,346 bp
  • T to C, chromosome 8 at 27,227,827 bp
  • A to T, chromosome 8 at 47,522,441 bp
  • T to A, chromosome 8 at 71,643,172 bp
  • A to G, chromosome 8 at 72,455,118 bp
  • T to A, chromosome 8 at 92,360,781 bp
  • T to C, chromosome 8 at 107,076,478 bp
  • T to A, chromosome 9 at 56,241,276 bp
  • T to C, chromosome 9 at 65,443,851 bp
  • C to A, chromosome 9 at 94,537,433 bp
  • T to C, chromosome 9 at 96,437,120 bp
  • T to A, chromosome 10 at 86,949,907 bp
  • C to T, chromosome 11 at 30,426,349 bp
  • C to T, chromosome 11 at 46,815,517 bp
  • A to G, chromosome 11 at 69,393,771 bp
  • G to T, chromosome 12 at 58,268,284 bp
  • A to G, chromosome 12 at 59,204,387 bp
  • A to G, chromosome 12 at 76,565,537 bp
  • A to G, chromosome 12 at 104,220,356 bp
  • G to T, chromosome 13 at 64,761,984 bp
  • G to A, chromosome 13 at 100,717,595 bp
  • A to T, chromosome 13 at 113,213,431 bp
  • G to A, chromosome 14 at 14,351,080 bp
  • A to T, chromosome 14 at 44,519,322 bp
  • A to T, chromosome 14 at 47,268,654 bp
  • T to A, chromosome 14 at 51,162,751 bp
  • T to A, chromosome 14 at 55,941,671 bp
  • A to G, chromosome 14 at 103,169,994 bp
  • T to A, chromosome 15 at 33,687,055 bp
  • T to A, chromosome 15 at 57,821,359 bp
  • A to G, chromosome 15 at 79,424,929 bp
  • T to C, chromosome 16 at 14,114,231 bp
  • A to T, chromosome 16 at 32,381,504 bp
  • G to A, chromosome 17 at 49,901,818 bp
  • A to G, chromosome 17 at 74,594,324 bp
  • A to G, chromosome 17 at 85,621,292 bp
  • T to A, chromosome 18 at 14,898,043 bp
  • A to T, chromosome 18 at 24,596,294 bp
  • G to A, chromosome X at 134,441,316 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4994 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042588-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.