Strain Name:
C57BL/6J-MtgxR4998Btlr/Mmmh
Stock Number:
042592-MU
Citation ID:
RRID:MMRRC_042592-MU
Other Names:
R4998 (G1), C57BL/6J-MtgxR4998Btlr
Major Collection:

Gene Information

Icos
Name: inducible T cell co-stimulator
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 54167
HGNC: HGNC:5351
Homologene: 8097
Gon4l
Name: gon-4-like (C.elegans)
Synonyms: 2610100B20Rik, 1500041I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 76022
Homologene: 13002
Socs3
Name: suppressor of cytokine signaling 3
Synonyms: cytokine-inducible SH2 protein 3, Cish3, CIS3, STAT-induced STAT inhibitor 3, SSI-3, E2a-Pbx1 target gene in fibroblasts 10, EF-10, SOCS-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 12702
Homologene: 2941
Rgs4
Name: regulator of G-protein signaling 4
Synonyms: ESTM48, ESTM50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 19736
Homologene: 4100
Brpf3
Name: bromodomain and PHD finger containing, 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 268936
Homologene: 16092
Npepps
Name: aminopeptidase puromycin sensitive
Synonyms: MP100, Psa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 19155
HGNC: HGNC:7900
Homologene: 36199
Rbbp6
Name: retinoblastoma binding protein 6, ubiquitin ligase
Synonyms: C030034J04Rik, 4933422O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 19647
HGNC: HGNC:9889
Homologene: 136812
Tg
Name: thyroglobulin
Synonyms: Tgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 21819
Homologene: 2430
Zfyve1
Name: zinc finger, FYVE domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217695
VEGA: 12
Homologene: 10945
Prdm15
Name: PR domain containing 15
Synonyms: E130018M06Rik, Zfp298
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 114604
Homologene: 56941
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 20191
VEGA: 13
Homologene: 37423
Pip4k2b
Name: phosphatidylinositol-5-phosphate 4-kinase, type II, beta
Synonyms: PI5P4Kbeta, c11, Pip5k2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 108083
HGNC: HGNC:8998
Homologene: 2634
Card6
Name: caspase recruitment domain family, member 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239319
Homologene: 13067
Enpp3
Name: ectonucleotide pyrophosphatase/phosphodiesterase 3
Synonyms: CD203c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 209558
VEGA: 10
HGNC: HGNC:3358
Homologene: 3683
Dnaaf4
Name: dynein axonemal assembly factor 4
Synonyms: 1700010I24Rik, b2b811Clo, EKN1, Dyx1c1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 67685
Homologene: 12173
Egfr
Name: epidermal growth factor receptor
Synonyms: Errb1, Wa5, 9030024J15Rik, Erbb, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 13649
HGNC: HGNC:3236
Homologene: 74545
Clca4b
Name: chloride channel accessory 4B
Synonyms: AI747448
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99709
HGNC: HGNC:2018
Homologene: 40808
Fchsd1
Name: FCH and double SH3 domains 1
Synonyms: A030002D08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 319262
Homologene: 14127
Dsg2
Name: desmoglein 2
Synonyms: D18Ertd293e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 13511
HGNC: HGNC:3049
Homologene: 1464
Baz1a
Name: bromodomain adjacent to zinc finger domain 1A
Synonyms: Gtl5, Wcrf180, Acf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217578
HGNC: HGNC:960
Homologene: 45654
Eif2b3
Name: eukaryotic translation initiation factor 2B, subunit 3
Synonyms: 1190002P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 108067
HGNC: HGNC:3259
Homologene: 7005
Ncstn
Name: nicastrin
Synonyms: Nct, nicastrin, D1Dau13e, 9430068N19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 59287
Homologene: 41029
2310022A10Rik
Name: RIKEN cDNA 2310022A10 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 66367
Homologene: 35272
Lsm14a
Name: LSM14A mRNA processing body assembly factor
Synonyms: 2700023B17Rik, Tral
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 67070
Homologene: 40537
Ttc13
Name: tetratricopeptide repeat domain 13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234875
Homologene: 11569
Otop1
Name: otopetrin 1
Synonyms: tlt, A530025J20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 21906
Homologene: 35244
Kif27
Name: kinesin family member 27
Synonyms: 4930517I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 75050
VEGA: 13
Homologene: 69235
Calcrl
Name: calcitonin receptor-like
Synonyms: CRLR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 54598
Homologene: 21179
Fcsk
Name: fucose kinase
Synonyms: Fuk, L-fucose kinase, 1110046B12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234730
Homologene: 15452
Slc5a8
Name: solute carrier family 5 (iodide transporter), member 8
Synonyms: SMCT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216225
VEGA: 10
Homologene: 64832
Tmem202
Name: transmembrane protein 202
Synonyms: 4930425N13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 73893
VEGA: 9
Homologene: 52264
Fbxo30
Name: F-box protein 30
Synonyms: 1700026A16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 71865
Homologene: 12959
Espn
Name: espin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 56226
Homologene: 23164
Fbn2
Name: fibrillin 2
Synonyms: Sne, Fib-2, sy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 14119
VEGA: 18
HGNC: HGNC:3604
Homologene: 1515
Plek
Name: pleckstrin
Synonyms: 2010300B13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 56193
HGNC: HGNC:9070
Homologene: 2000
Prr29
Name: proline rich 29
Synonyms: 2310007L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 75573
Homologene: 130357
Ucp1
Name: uncoupling protein 1 (mitochondrial, proton carrier)
Synonyms: Slc25a7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 22227
Homologene: 22524
Slc25a45
Name: solute carrier family 25, member 45
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 107375
Homologene: 76679
Shmt2
Name: serine hydroxymethyltransferase 2 (mitochondrial)
Synonyms: 2700043D08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 108037
VEGA: 10
Homologene: 133984
Pcdha1
Name: protocadherin alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 116731
HGNC: HGNC:8663
Homologene: 75093
Gypa
Name: glycophorin A
Synonyms: CD235a, GPA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 14934
HGNC: HGNC:4702
Gpr158
Name: G protein-coupled receptor 158
Synonyms: 5330427M13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241263
Homologene: 19381
Slc4a10
Name: solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
Synonyms: NCBE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 94229
Homologene: 23340
Cldn10
Name: claudin 10
Synonyms: 6720456I16Rik, D14Ertd728e, Cldn10b, Cldn10a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 58187
HGNC: HGNC:2033
Homologene: 5076
Col6a4
Name: collagen, type VI, alpha 4
Synonyms: Dvwa, Vwa6, EG235580, 1110001D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 68553
Homologene: 130754
Zbtb4
Name: zinc finger and BTB domain containing 4
Synonyms: 9230111I22Rik, 2310026P19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 75580
Homologene: 10846
Gys1
Name: glycogen synthase 1, muscle
Synonyms: MGS, Gys3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 14936
HGNC: HGNC:4706
Homologene: 113557
Edar
Name: ectodysplasin-A receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 13608
HGNC: HGNC:2895
Homologene: 7699
Ninl
Name: ninein-like
Synonyms: LOC381388, LOC381387, 4930519N13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 78177
Homologene: 57024
Rap1gap
Name: Rap1 GTPase-activating protein
Synonyms: 1300019I11Rik, Rap1ga1, Gap, 2310004O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 110351
HGNC: HGNC:9858
Homologene: 2163
Ankrd42
Name: ankyrin repeat domain 42
Synonyms: 4933417L02Rik, Ikbn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 73845
Homologene: 23652
Zfp879
Name: zinc finger protein 879
Synonyms: 9630041N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 214779
Homologene: 45452
Tmc3
Name: transmembrane channel-like gene family 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233424
Homologene: 45588
Them4
Name: thioesterase superfamily member 4
Synonyms: 4921507I02Rik, 2700077M13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 75778
Homologene: 14208
Igfn1
Name: immunoglobulin-like and fibronectin type III domain containing 1
Synonyms: 9830123M21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226438
Homologene: 130054
Gm10722
Name: predicted gene 10722
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
Tkt
Name: transketolase
Synonyms: p68
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 21881
Homologene: 68154
Pcyt1a
Name: phosphate cytidylyltransferase 1, choline, alpha isoform
Synonyms: Ctpct, Cctalpha, Cttalpha, CTP:phosphocholine cytidylyltransferase alpha, CTalpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 13026
HGNC: HGNC:8754
Homologene: 3680
Hdac10
Name: histone deacetylase 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 170787
Homologene: 23749
Chil5
Name: chitinase-like 5
Synonyms: Bclp1, Chi3l7, Bclp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229687
Homologene: 132668
Zfp422-ps
Name: zinc finger protein 422, pseudogene
Synonyms: Zfp422-rs1, Krox-25-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 100416808
Ptpru
Name: protein tyrosine phosphatase, receptor type, U
Synonyms: Ptprl, RPTPlambda
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 19273
HGNC: HGNC:9683
Homologene: 4168
Olfr1076
Name: olfactory receptor 1076
Synonyms: MOR189-2, GA_x6K02T2Q125-47993761-47994702
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258401
Homologene: 17233
Dip2a
Name: disco interacting protein 2 homolog A
Synonyms: 4931420H10Rik, Dip2, Kiaa0184-hp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 64451
Homologene: 41012
Cyp2a4
Name: cytochrome P450, family 2, subfamily a, polypeptide 4
Synonyms: D7Ucla4, Cyp15a1, testosterone 15alpha-hydroxylase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 13086
Homologene: 85917
Fam57b
Name: family with sequence similarity 57, member B
Synonyms: A330104J06Rik, 1500016O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 68952
Homologene: 69491
Fam107a
Name: family with sequence similarity 107, member A
Synonyms: DRR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 268709
Homologene: 48509
Cyp27b1
Name: cytochrome P450, family 27, subfamily b, polypeptide 1
Synonyms: 1alpha(OH)ase, 25-hydroxyvitamin D3 1alpha-hydroxylase, 25(OH)D 1alpha-hydroxylase, VddrI, P450c1, Cyp27b, Vddr, Vdd1, Pddr, Cyp1, Cp2b, Cyp40, P450VD1alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 13115
HGNC: HGNC:2606
Homologene: 37139
Shc3
Name: src homology 2 domain-containing transforming protein C3
Synonyms: N-Shc, ShcC, Rai
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 20418
VEGA: 13
Homologene: 7536
Zfp69
Name: zinc finger protein 69
Synonyms: Zfp63, KRAB2, LOC381549
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 381549
Homologene: 45693
Tmem132a
Name: transmembrane protein 132A
Synonyms: Hspa5bp1, 6720481D13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 98170
Homologene: 75076
Lrriq3
Name: leucine-rich repeats and IQ motif containing 3
Synonyms: 4933403H06Rik, Lrrc44, 4930511J15Rik, 4930438B07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 74435
Homologene: 23668
Trhr2
Name: thyrotropin releasing hormone receptor 2
Synonyms: TRH-R2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 170732
Homologene: 44052
Sema6c
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
Synonyms: Semay, Sema Y
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 20360
Homologene: 7931
Lin28a
Name: lin-28 homolog A (C. elegans)
Synonyms: Tex17, Lin-28, Lin28, Lin28a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 83557
Homologene: 32592
Npb
Name: neuropeptide B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 208990
Homologene: 102151
Pdpr
Name: pyruvate dehydrogenase phosphatase regulatory subunit
Synonyms: 4930402E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 319518
Homologene: 9948
Gm6994
Name: predicted gene 6994
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 629678
Snx31
Name: sorting nexin 31
Synonyms: 4631426E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 66696
Homologene: 23551
Platr26
Name: pluripotency associated transcript 26
Synonyms: LOC381371, Gm1631
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 381371
Mmel1
Name: membrane metallo-endopeptidase-like 1
Synonyms: NEPLP gamma, NEPLP beta, Mell1, Nep2, NEPLP alpha, SEP, Nl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 27390
Homologene: 22778
Defb8
Name: defensin beta 8
Synonyms: Defr1, mBD8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244334
Coq3
Name: coenzyme Q3 methyltransferase
Synonyms: C77934
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230027
Homologene: 9683
Cd70
Name: CD70 antigen
Synonyms: Tnfsf7, CD27LG, Ki-24 antigen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 21948
VEGA: 17
Homologene: 956
Cx3cl1
Name: chemokine (C-X3-C motif) ligand 1
Synonyms: fractalkine, D8Bwg0439e, neurotactin, Scyd1, CX3C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 20312
Homologene: 2251
Ramp2
Name: receptor (calcitonin) activity modifying protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 54409
HGNC: HGNC:9844
Homologene: 4274
Cox8b
Name: cytochrome c oxidase subunit 8B
Synonyms: COX8H, COX VIII-H
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 12869
Homologene: 7277
Gm26919
Name: predicted gene, 26919
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
Homologene: 134227
Gm26870
Name: predicted gene, 26870
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
Trbc1
Name: T cell receptor beta, constant region 1
Synonyms: Tcrb-C1, Gm16802
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 100125262
Gm17416
Name: predicted gene, 17416
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
RP23-468H22.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 60,993,782 bp
  • T to A, chromosome 1 at 135,954,666 bp
  • C to T, chromosome 1 at 169,745,233 bp
  • T to A, chromosome 1 at 172,071,520 bp
  • G to A, chromosome 2 at 21,648,983 bp
  • G to C, chromosome 2 at 62,244,439 bp
  • G to A, chromosome 2 at 71,730,870 bp
  • A to T, chromosome 2 at 84,339,314 bp
  • T to C, chromosome 2 at 86,509,355 bp
  • A to G, chromosome 2 at 150,953,364 bp
  • C to A, chromosome 2 at 152,569,507 bp
  • G to T, chromosome 3 at 88,899,998 bp
  • G to T, chromosome 3 at 94,329,781 bp
  • T to C, chromosome 3 at 95,170,474 bp
  • T to A, chromosome 3 at 106,019,932 bp
  • C to T, chromosome 3 at 144,915,508 bp
  • T to A, chromosome 3 at 155,188,058 bp
  • A to G, chromosome 4 at 21,900,296 bp
  • A to C, chromosome 4 at 117,066,392 bp
  • A to T, chromosome 4 at 120,947,325 bp
  • A to G, chromosome 4 at 131,776,885 bp
  • A to C, chromosome 4 at 134,018,717 bp
  • A to G, chromosome 4 at 137,728,284 bp
  • A to T, chromosome 4 at 152,135,583 bp
  • A to G, chromosome 4 at 154,885,510 bp
  • G to A, chromosome 5 at 38,294,548 bp
  • G to A, chromosome 6 at 41,539,336 bp
  • A to T, chromosome 6 at 130,676,538 bp
  • G to T, chromosome 7 at 26,307,361 bp
  • T to C, chromosome 7 at 27,571,663 bp
  • T to C, chromosome 7 at 34,375,374 bp
  • C to A, chromosome 7 at 45,451,544 bp
  • C to A, chromosome 7 at 83,622,321 bp
  • T to C, chromosome 7 at 92,624,074 bp
  • T to A, chromosome 7 at 122,990,326 bp
  • C to T, chromosome 7 at 126,827,623 bp
  • T to C, chromosome 7 at 140,899,088 bp
  • T to C, chromosome 8 at 19,447,587 bp
  • G to C, chromosome 8 at 69,453,358 bp
  • T to A, chromosome 8 at 80,496,335 bp
  • A to G, chromosome 8 at 83,297,855 bp
  • C to G, chromosome 8 at 94,780,425 bp
  • G to A, chromosome 8 at 110,887,803 bp
  • G to T, chromosome 8 at 111,114,768 bp
  • A to G, chromosome 8 at 122,358,772 bp
  • A to T, chromosome 8 at 124,680,056 bp
  • A to C, chromosome 9 at 3,001,041 bp
  • T to G, chromosome 9 at 3,038,073 bp
  • A to G, chromosome 9 at 59,524,846 bp
  • A to G, chromosome 9 at 72,960,678 bp
  • A to G, chromosome 9 at 105,990,778 bp
  • T to A, chromosome 10 at 11,290,763 bp
  • C to A, chromosome 10 at 24,807,538 bp
  • T to C, chromosome 10 at 58,606,093 bp
  • A to T, chromosome 10 at 76,319,556 bp
  • T to C, chromosome 10 at 88,908,057 bp
  • T to C, chromosome 10 at 127,049,872 bp
  • A to T, chromosome 10 at 127,518,270 bp
  • A to G, chromosome 11 at 16,881,493 bp
  • A to G, chromosome 11 at 16,983,194 bp
  • A to G, chromosome 11 at 50,837,969 bp
  • C to T, chromosome 11 at 69,778,671 bp
  • A to G, chromosome 11 at 97,206,107 bp
  • T to C, chromosome 11 at 97,722,435 bp
  • T to A, chromosome 11 at 101,247,421 bp
  • T to G, chromosome 11 at 106,376,953 bp
  • T to C, chromosome 11 at 117,967,716 bp
  • T to C, chromosome 11 at 120,608,575 bp
  • T to C, chromosome 12 at 54,975,137 bp
  • T to C, chromosome 12 at 83,548,065 bp
  • C to T, chromosome 13 at 11,643,895 bp
  • G to A, chromosome 13 at 51,442,820 bp
  • A to G, chromosome 13 at 58,293,143 bp
  • T to C, chromosome 14 at 8,299,514 bp
  • G to A, chromosome 14 at 30,565,542 bp
  • A to T, chromosome 14 at 77,501,435 bp
  • G to A, chromosome 14 at 118,788,313 bp
  • T to C, chromosome 15 at 5,100,082 bp
  • A to G, chromosome 15 at 36,539,367 bp
  • A to G, chromosome 15 at 66,674,050 bp
  • T to A, chromosome 15 at 89,123,940 bp
  • A to G, chromosome 16 at 32,451,842 bp
  • A to T, chromosome 16 at 97,794,489 bp
  • C to T, chromosome 17 at 28,835,905 bp
  • T to A, chromosome 17 at 33,305,151 bp
  • A to T, chromosome 17 at 57,146,311 bp
  • A to T, chromosome 18 at 20,601,521 bp
  • T to C, chromosome 18 at 36,932,416 bp
  • C to T, chromosome 18 at 37,959,873 bp
  • A to T, chromosome 18 at 58,072,631 bp
  • A to T, chromosome 19 at 5,884,917 bp
  • G to T, chromosome 19 at 10,858,941 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4998 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042592-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.