Strain Name:
C57BL/6J-MtgxR5017Btlr/Mmmh
Stock Number:
042608-MU
Citation ID:
RRID:MMRRC_042608-MU
Other Names:
R5017 (G1), C57BL/6J-MtgxR5017Btlr
Major Collection:

Gene Information

Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: trabeculin alpha, Acf7, Aclp7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11426
Homologene: 136191
Birc2
Name: baculoviral IAP repeat-containing 2
Synonyms: Api1, cIAP1, IAP1, cIAP-1, MIAP1, mcIAP1, MIHB, HIAP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 11797
HGNC: HGNC:590
Homologene: 900
Polr1c
Name: polymerase (RNA) I polypeptide C
Synonyms: Rpo1-1, 40kDa, RPA40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20016
Homologene: 3586
Tpr
Name: translocated promoter region, nuclear basket protein
Synonyms: 2610029M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 108989
Homologene: 37753
Trip11
Name: thyroid hormone receptor interactor 11
Synonyms: 3110031G15Rik, 6030460N08Rik, 2610511G22Rik, GMAP-210, TRIP230
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 109181
Homologene: 20897
Cog5
Name: component of oligomeric golgi complex 5
Synonyms: GOLTC1, GTC90, 5430405C01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238123
VEGA: 12
Homologene: 42221
Uhrf1bp1
Name: UHRF1 (ICBP90) binding protein 1
Synonyms: F830021D11Rik, 1110020K19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224648
Homologene: 9816
Xpo6
Name: exportin 6
Synonyms: Ranbp20, 2610005L19Rik, C230091E20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74204
Homologene: 12544
Phkb
Name: phosphorylase kinase beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 102093
HGNC: HGNC:8927
Homologene: 247
Slc25a46
Name: solute carrier family 25, member 46
Synonyms: 1200007B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 67453
VEGA: 18
Homologene: 14518
Mafa
Name: v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
Synonyms: RIPE3b1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 378435
VEGA: 15
Homologene: 65867
Fchsd1
Name: FCH and double SH3 domains 1
Synonyms: A030002D08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 319262
Homologene: 14127
Arhgef3
Name: Rho guanine nucleotide exchange factor (GEF) 3
Synonyms: 9830169H03Rik, C76747, 1200004I24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 71704
VEGA: 14
HGNC: HGNC:683
Homologene: 41329
Siglecg
Name: sialic acid binding Ig-like lectin G
Synonyms: mSiglec-G, A630096C01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243958
Homologene: 13228
Muc6
Name: mucin 6, gastric
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 353328
HGNC: HGNC:7517
Homologene: 18768
Trpm1
Name: transient receptor potential cation channel, subfamily M, member 1
Synonyms: Mlsn1, melastatin, LTRPC1, 4732499L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17364
HGNC: HGNC:7146
Homologene: 19940
Gdpd4
Name: glycerophosphodiester phosphodiesterase domain containing 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233537
Homologene: 18606
Sycp1
Name: synaptonemal complex protein 1
Synonyms: SCP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20957
Homologene: 2389
Phldb3
Name: pleckstrin homology like domain, family B, member 3
Synonyms: Gm10102, EG232970
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232970
Homologene: 109375
Shank2
Name: SH3 and multiple ankyrin repeat domains 2
Synonyms: ProSAP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 210274
Homologene: 105965
Zfp276
Name: zinc finger protein (C2H2 type) 276
Synonyms: D8Ertd377e, D8Ertd370e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 57247
Homologene: 10731
Pla2r1
Name: phospholipase A2 receptor 1
Synonyms: M-type receptor, Pla2g1br, PLA2-I receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18779
HGNC: HGNC:9042
Homologene: 32016
Tmem132c
Name: transmembrane protein 132C
Synonyms: 2810482M11Rik, 4632425D07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 208213
Homologene: 76567
Gm10722
Name: predicted gene 10722
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Lrrc9
Name: leucine rich repeat containing 9
Synonyms: 4930432K16Rik, 4921529O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 78257
Homologene: 12692
Adamdec1
Name: ADAM-like, decysin 1
Synonyms: 2210414L24Rik, Dcsn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 58860
VEGA: 14
Homologene: 8711
Olfr44
Name: olfactory receptor 44
Synonyms: MOR171-5, GA_x6K02T2PVTD-33181773-33180838, IB3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 18343
VEGA: 9
Homologene: 133633
Kcnh8
Name: potassium voltage-gated channel, subfamily H (eag-related), member 8
Synonyms: Kv12.1, ELK1, C130090D05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 211468
Homologene: 14332
Nostrin
Name: nitric oxide synthase trafficker
Synonyms: mDaIP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329416
Homologene: 43142
Tmem256
Name: transmembrane protein 256
Synonyms: 3110009M16Rik, 1810027O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69186
Homologene: 45148
Pde11a
Name: phosphodiesterase 11A
Synonyms: A630086N24Rik, 6330414F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241489
HGNC: HGNC:8773
Homologene: 56763
Cep44
Name: centrosomal protein 44
Synonyms: 4933440G23Rik, BC088983
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 382010
Homologene: 12738
Hapln2
Name: hyaluronan and proteoglycan link protein 2
Synonyms: 4930401E20Rik, Bral1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 73940
Homologene: 11045
Agbl5
Name: ATP/GTP binding protein-like 5
Synonyms: 9430057O19Rik, Ccp5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231093
Homologene: 11053
Trdn
Name: triadin
Synonyms: triadin-2, EG432451, triadin 2, triadin-3, 2310045H21Rik, triadin 3, triadin-1, triadin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 76757
VEGA: 10
Homologene: 38137
Clstn2
Name: calsyntenin 2
Synonyms: CSTN2, 2900042C18Rik, CS2, Cst-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 64085
Homologene: 49698
Olfr981
Name: olfactory receptor 981
Synonyms: GA_x6K02T2PVTD-33720892-33721824, MOR223-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258283
VEGA: 9
Homologene: 64849
Endod1
Name: endonuclease domain containing 1
Synonyms: 2210414F18Rik, 2310067E08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71946
VEGA: 9
Homologene: 12425
Setbp1
Name: SET binding protein 1
Synonyms: Seb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240427
Homologene: 9192
Pigu
Name: phosphatidylinositol glycan anchor biosynthesis, class U
Synonyms: Cdc91l1, 5430426F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228812
Homologene: 6553
Ifit3
Name: interferon-induced protein with tetratricopeptide repeats 3
Synonyms: Ifi49
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 15959
HGNC: HGNC:5411
Homologene: 1189
Olfr160
Name: olfactory receptor 160
Synonyms: MOR171-3, MOR171-3, GA_x6K02T2PVTD-31389446-31388517, M72
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 80706
HGNC: HGNC:8469
Homologene: 12726
Vmn1r227
Name: vomeronasal 1 receptor 227
Synonyms: V1re6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 171229
Gm15587
Name: predicted gene 15587
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
RP23-37I24.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 150,398,637 bp
  • A to G, chromosome 2 at 60,522,760 bp
  • G to A, chromosome 2 at 69,183,883 bp
  • A to T, chromosome 2 at 76,136,367 bp
  • A to T, chromosome 2 at 155,299,208 bp
  • A to G, chromosome 3 at 88,024,001 bp
  • A to T, chromosome 3 at 102,895,987 bp
  • A to G, chromosome 4 at 123,452,113 bp
  • A to G, chromosome 5 at 24,366,719 bp
  • G to A, chromosome 5 at 30,903,059 bp
  • T to A, chromosome 5 at 63,650,141 bp
  • A to G, chromosome 5 at 127,563,350 bp
  • C to T, chromosome 7 at 24,620,096 bp
  • T to A, chromosome 7 at 43,411,386 bp
  • T to C, chromosome 7 at 64,244,832 bp
  • C to A, chromosome 7 at 98,004,275 bp
  • G to A, chromosome 7 at 126,104,747 bp
  • T to C, chromosome 7 at 141,640,528 bp
  • T to C, chromosome 7 at 144,420,754 bp
  • A to G, chromosome 8 at 56,544,207 bp
  • A to T, chromosome 8 at 86,049,809 bp
  • A to G, chromosome 8 at 123,264,977 bp
  • T to C, chromosome 9 at 3,000,937 bp
  • A to T, chromosome 9 at 7,818,885 bp
  • G to A, chromosome 9 at 14,356,891 bp
  • A to T, chromosome 9 at 37,711,525 bp
  • A to T, chromosome 9 at 39,484,755 bp
  • A to T, chromosome 9 at 40,022,376 bp
  • A to G, chromosome 9 at 97,483,086 bp
  • A to G, chromosome 10 at 33,468,159 bp
  • T to C, chromosome 11 at 69,838,992 bp
  • T to A, chromosome 12 at 31,920,605 bp
  • C to A, chromosome 12 at 72,506,325 bp
  • T to C, chromosome 12 at 101,846,620 bp
  • G to T, chromosome 14 at 27,265,530 bp
  • T to C, chromosome 14 at 68,573,245 bp
  • T to C, chromosome 15 at 75,747,489 bp
  • T to C, chromosome 17 at 20,736,078 bp
  • T to A, chromosome 17 at 27,894,739 bp
  • G to T, chromosome 17 at 46,247,709 bp
  • T to C, chromosome 17 at 52,893,930 bp
  • A to T, chromosome 18 at 31,605,783 bp
  • C to T, chromosome 18 at 37,959,873 bp
  • C to A, chromosome 18 at 78,856,594 bp
  • A to C, chromosome 19 at 34,587,192 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5017 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042608-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.