Strain Name:
C57BL/6J-MtgxR5029Btlr/Mmmh
Stock Number:
042620-MU
Citation ID:
RRID:MMRRC_042620-MU
Other Names:
R5029 (G1), C57BL/6J-MtgxR5029Btlr
Major Collection:

Gene Information

Pik3cb
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
Synonyms: 1110001J02Rik, p110beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74769
HGNC: HGNC:8976
Homologene: 21250
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Pam, C130061D10Rik, Phr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105689
Homologene: 9005
Ndc80
Name: NDC80 kinetochore complex component
Synonyms: HEC1, 2610020P18Rik, Kntc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 67052
VEGA: 17
Homologene: 38141
St13
Name: suppression of tumorigenicity 13
Synonyms: PRO0786, HSPABP1, SNC6, p48, Hsp70 interacting protein, 3110002K08Rik, 1110007I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 70356
Homologene: 2921
Cnot4
Name: CCR4-NOT transcription complex, subunit 4
Synonyms: Not4h, Not4, Not4hp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 53621
HGNC: HGNC:7880
Homologene: 40870
Nup205
Name: nucleoporin 205
Synonyms: 3830404O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 70699
Homologene: 45971
Ints4
Name: integrator complex subunit 4
Synonyms: 2610034N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101861
Homologene: 69427
Bnip3
Name: BCL2/adenovirus E1B interacting protein 3
Synonyms: Nip3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12176
HGNC: HGNC:1084
Homologene: 2990
Dync1h1
Name: dynein cytoplasmic 1 heavy chain 1
Synonyms: MAP1C, dynein heavy chain, retrograde transport, Dnec1, Loa, 9930018I23Rik, Dnchc1, Swl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 13424
HGNC: HGNC:2961
Homologene: 1053
N4bp2
Name: NEDD4 binding protein 2
Synonyms: LOC333789, LOC386488, B3bp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 333789
Homologene: 32396
Ccdc117
Name: coiled-coil domain containing 117
Synonyms: 1700026O03Rik, 1110004K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 104479
Homologene: 15886
Tomm70a
Name: translocase of outer mitochondrial membrane 70A
Synonyms: D16Ium22, D16Ium22e, 2610044B22Rik, Tomm70a, D16Wsu109e, Tom70
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 28185
VEGA: 16
Homologene: 40112
Slc39a4
Name: solute carrier family 39 (zinc transporter), member 4
Synonyms: zip4, 1600025H15Rik, AWMS2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 72027
VEGA: 15
Homologene: 15638
Vps13d
Name: vacuolar protein sorting 13D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230895
Homologene: 15583
Pacs1
Name: phosphofurin acidic cluster sorting protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 107975
VEGA: 19
Homologene: 9970
Nxn
Name: nucleoredoxin
Synonyms: l11Jus13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18230
Homologene: 69028
M1ap
Name: meiosis 1 associated protein
Synonyms: D6Mm5e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 110958
Homologene: 13210
Zfyve26
Name: zinc finger, FYVE domain containing 26
Synonyms: 9330197E15Rik, LOC380767, A630028O16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 211978
VEGA: 12
Homologene: 9102
Mfng
Name: MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Synonyms: manic fringe
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 17305
HGNC: HGNC:7038
Homologene: 1803
Dact2
Name: dishevelled-binding antagonist of beta-catenin 2
Synonyms: dapper2, 2900084M21Rik, Frd2, Dpr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 240025
VEGA: 17
Homologene: 18237
Ank
Name: progressive ankylosis
Synonyms: D15Ertd221e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 11732
Homologene: 10664
Sh3bgrl2
Name: SH3 domain binding glutamic acid-rich protein like 2
Synonyms: A930014C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 212531
Homologene: 12876
Klrg1
Name: killer cell lectin-like receptor subfamily G, member 1
Synonyms: 2F1-Ag
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 50928
HGNC: HGNC:6380
Homologene: 4244
Tnik
Name: TRAF2 and NCK interacting kinase
Synonyms: 4831440I19Rik, 1500031A17Rik, C530008O15Rik, C630040K21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 665113
Homologene: 77943
Myh11
Name: myosin, heavy polypeptide 11, smooth muscle
Synonyms: smMHC, SM2, SM1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 17880
VEGA: 16
HGNC: HGNC:7569
Homologene: 128512
Fer1l6
Name: fer-1-like 6 (C. elegans)
Synonyms: EG631797
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 631797
Homologene: 53396
Olfr371
Name: olfactory receptor 371
Synonyms: GA_x6K02T2NUPS-13298842-13299780, MOR141-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 258858
Homologene: 65998
Ppfia2
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
Synonyms: E130120L08Rik, Liprin-alpha2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 327814
VEGA: 10
HGNC: HGNC:9246
Homologene: 27953
Defa21
Name: defensin, alpha, 21
Synonyms: 2010016B13Rik, Defcr21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 66298
Homologene: 113382
Gm4787
Name: predicted gene 4787
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 214321
Homologene: 86950
Cdh4
Name: cadherin 4
Synonyms: Rcad, R-cadherin, R-Cadh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12561
HGNC: HGNC:1763
Homologene: 48044
C1galt1
Name: core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
Synonyms: core 1 beta3-Gal-T, 2210410E06Rik, T-synthase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 94192
Homologene: 10599
Zmynd15
Name: zinc finger, MYND-type containing 15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 574428
Homologene: 12995
Plxnb1
Name: plexin B1
Synonyms: 2900002G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235611
HGNC: HGNC:9103
Homologene: 130508
Olfr1057
Name: olfactory receptor 1057
Synonyms: GA_x6K02T2Q125-47844843-47843896, MOR185-11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 404325
Homologene: 83135
Dstyk
Name: dual serine/threonine and tyrosine protein kinase
Synonyms: A930019K20Rik, C430014H23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 213452
Homologene: 19711
Hpx
Name: hemopexin
Synonyms: hx, Hpxn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 15458
HGNC: HGNC:5171
Homologene: 511
Col17a1
Name: collagen, type XVII, alpha 1
Synonyms: BPAg2, BP180, Bpag, Bpag2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 12821
HGNC: HGNC:2194
Homologene: 7276
Ebf4
Name: early B cell factor 4
Synonyms: Olf-1/EBF-like 4, O/E-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228598
Homologene: 65064
Tlr1
Name: toll-like receptor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 21897
Homologene: 20694
Cbs
Name: cystathionine beta-synthase
Synonyms: HIP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12411
Homologene: 37258
Dimt1
Name: DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)
Synonyms: 1500031M22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 66254
VEGA: 13
Homologene: 7047
Psg22
Name: pregnancy-specific glycoprotein 22
Synonyms: cea9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243862
Homologene: 110989
Vmn2r97
Name: vomeronasal 2, receptor 97
Synonyms: EG627367
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 627367
Homologene: 115024
Jph1
Name: junctophilin 1
Synonyms: mitsugumin72, JP-1, ENSMUSG00000054314
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 57339
Homologene: 10761
Stpg3
Name: sperm tail PG rich repeat containing 3
Synonyms: 4933433C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74472
Homologene: 52838
Actbl2
Name: actin, beta-like 2
Synonyms: 4732495G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238880
Homologene: 134276
Olfr776
Name: olfactory receptor 776
Synonyms: GA_x6K02T2PULF-10947193-10948131, MOR111-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 404321
Homologene: 115559
Saraf
Name: store-operated calcium entry-associated regulatory factor
Synonyms: 1810045K07Rik, Tmem66
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 67887
Homologene: 9398
Gm4744
Name: predicted gene 4744
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 194360
Pcdhga12
Name: protocadherin gamma subfamily A, 12
Synonyms: pc2c, Pcdh13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93724
HGNC: HGNC:8699
Homologene: 134588
Gm26996
Name: predicted gene, 26996
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Taf1a
Name: TATA-box binding protein associated factor, RNA polymerase I, A
Synonyms: mTAFI48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 21339
Homologene: 4155
1500002C15Rik
Name: RIKEN cDNA 1500002C15 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 102636313
B230344G16Rik
Name: RIKEN cDNA B230344G16 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 100038636
VEGA: 11
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 17,091,391 bp
  • G to T, chromosome 1 at 132,449,324 bp
  • T to A, chromosome 1 at 183,395,935 bp
  • T to C, chromosome 2 at 25,214,564 bp
  • A to G, chromosome 2 at 86,374,890 bp
  • A to G, chromosome 2 at 130,361,685 bp
  • T to A, chromosome 2 at 179,881,949 bp
  • G to A, chromosome 3 at 28,665,844 bp
  • T to C, chromosome 4 at 145,156,282 bp
  • T to C, chromosome 4 at 155,734,176 bp
  • T to A, chromosome 5 at 64,925,681 bp
  • A to G, chromosome 5 at 65,814,780 bp
  • A to G, chromosome 6 at 7,863,931 bp
  • T to C, chromosome 6 at 35,078,027 bp
  • C to T, chromosome 6 at 35,224,676 bp
  • T to A, chromosome 6 at 40,949,407 bp
  • A to C, chromosome 6 at 83,003,832 bp
  • A to G, chromosome 6 at 122,282,735 bp
  • C to T, chromosome 6 at 130,578,877 bp
  • A to G, chromosome 7 at 18,719,737 bp
  • A to G, chromosome 7 at 97,509,774 bp
  • T to G, chromosome 7 at 105,591,764 bp
  • T to A, chromosome 7 at 138,898,119 bp
  • A to T, chromosome 8 at 21,026,365 bp
  • G to T, chromosome 8 at 34,161,258 bp
  • C to T, chromosome 8 at 85,231,206 bp
  • T to C, chromosome 9 at 83,548,489 bp
  • A to T, chromosome 9 at 99,054,060 bp
  • T to C, chromosome 9 at 109,114,655 bp
  • C to A, chromosome 10 at 106,857,443 bp
  • T to A, chromosome 10 at 129,261,838 bp
  • T to C, chromosome 11 at 5,534,897 bp
  • G to T, chromosome 11 at 70,462,561 bp
  • A to C, chromosome 11 at 76,274,530 bp
  • A to T, chromosome 11 at 115,988,591 bp
  • A to T, chromosome 12 at 79,286,323 bp
  • G to C, chromosome 12 at 81,377,830 bp
  • T to A, chromosome 12 at 110,618,010 bp
  • A to G, chromosome 13 at 106,957,122 bp
  • T to A, chromosome 13 at 111,255,593 bp
  • A to G, chromosome 14 at 103,156,510 bp
  • T to C, chromosome 15 at 27,590,353 bp
  • A to T, chromosome 15 at 58,643,920 bp
  • C to T, chromosome 15 at 76,614,083 bp
  • C to T, chromosome 15 at 78,764,388 bp
  • G to C, chromosome 15 at 81,399,585 bp
  • T to A, chromosome 16 at 14,205,625 bp
  • T to A, chromosome 16 at 57,122,151 bp
  • A to T, chromosome 17 at 14,195,852 bp
  • T to A, chromosome 17 at 18,947,911 bp
  • T to A, chromosome 17 at 31,615,482 bp
  • A to C, chromosome 17 at 71,508,765 bp
  • T to C, chromosome 18 at 37,766,811 bp
  • A to G, chromosome 19 at 5,142,271 bp
  • A to G, chromosome 19 at 47,669,368 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5029 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042620-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.