Strain Name:
C57BL/6J-MtgxR5087Btlr/Mmmh
Stock Number:
042676-MU
Citation ID:
RRID:MMRRC_042676-MU
Other Names:
R5087 (G1), C57BL/6J-MtgxR5087Btlr
Major Collection:

Strain Information

Cnst
Name: consortin, connexin sorting protein
Synonyms: 9630058J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226744
Homologene: 17139
Hells
Name: helicase, lymphoid specific
Synonyms: Lysh, proliferation-associated SNF2-like, PASG, LSH, YFK8, E130115I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 15201
HGNC: HGNC:4861
Homologene: 50037
Vps35l
Name: VPS35 endosomal protein sorting factor like
Synonyms: 9030624J02Rik, Vsp35l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 71517
Homologene: 10659
Hdlbp
Name: high density lipoprotein (HDL) binding protein
Synonyms: D1Ertd101e, 1110005P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 110611
HGNC: HGNC:4857
Homologene: 38035
Naa15
Name: N(alpha)-acetyltransferase 15, NatA auxiliary subunit
Synonyms: 5730450D16Rik, tubedown, Tbdn-1, mNAT1, Narg1, ASTBDN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 74838
Homologene: 14211
Usp25
Name: ubiquitin specific peptidase 25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 30940
VEGA: 16
Homologene: 8374
Dctn1
Name: dynactin 1
Synonyms: Glued, p150, p150glued
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 13191
HGNC: HGNC:2711
Homologene: 3011
Anln
Name: anillin, actin binding protein
Synonyms: 1110037A17Rik, Scraps, 2900037I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 68743
VEGA: 9
Homologene: 41281
Lrrc1
Name: leucine rich repeat containing 1
Synonyms: A430093J20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 214345
Homologene: 44445
Naa16
Name: N(alpha)-acetyltransferase 16, NatA auxiliary subunit
Synonyms: 1300019C06Rik, Narg1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 66897
Homologene: 134838
Gucy2c
Name: guanylate cyclase 2c
Synonyms: GC-C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14917
HGNC: HGNC:4688
Homologene: 3641
Got2
Name: glutamatic-oxaloacetic transaminase 2, mitochondrial
Synonyms: mAspAT, mitochondrial aspartate aminotransferase, FABP-pm, plasma membrane fatty acid binding protein, Kyat4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14719
HGNC: HGNC:4433
Homologene: 1572
Ntng1
Name: netrin G1
Synonyms: Lmnt1, A930010C08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 80883
Homologene: 8949
Zfy1
Name: zinc finger protein 1, Y-linked
Synonyms: Zfy-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
NCBI: 22767
Homologene: 56456
Eipr1
Name: EARP complex and GARP complex interacting protein 1
Synonyms: D12Ertd604e, Tssc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 380752
VEGA: 12
Homologene: 2481
Cpq
Name: carboxypeptidase Q
Synonyms: HLS2, 1190003P12Rik, 2610034C17Rik, Lal-1, Pgcp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 54381
VEGA: 15
Homologene: 9401
Sass6
Name: SAS-6 centriolar assembly protein
Synonyms: 2810453L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 72776
Homologene: 45668
Slc25a27
Name: solute carrier family 25, member 27
Synonyms: D530043E16Rik, Ucp4, 3632410G24Rik, 9430092A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 74011
VEGA: 17
Homologene: 12523
Ighd
Name: immunoglobulin heavy constant delta
Synonyms: IgD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 380797
HGNC: HGNC:5480
Fbxo33
Name: F-box protein 33
Synonyms: 5730501N20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 70611
Homologene: 16501
Ghr
Name: growth hormone receptor
Synonyms: GHBP, GHR/BP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 14600
HGNC: HGNC:4263
Homologene: 134
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Pld1
Name: phospholipase D1
Synonyms: Pld1b, Pld1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18805
HGNC: HGNC:9067
Homologene: 116234
Itga4
Name: integrin alpha 4
Synonyms: VLA-4 receptor, alpha 4 subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16401
HGNC: HGNC:6140
Homologene: 37364
Stard9
Name: START domain containing 9
Synonyms: N-3 kinesin, Kif16a, 4831403C07Rik, E230025N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 668880
Homologene: 130712
Vmn1r58
Name: vomeronasal 1 receptor 58
Synonyms: V3R4, V1rd4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 81014
Homologene: 41799
Rabgap1l
Name: RAB GTPase activating protein 1-like
Synonyms: Hh1, 9630005B12Rik, 5830411O09Rik, 8430421H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 29809
Homologene: 8143
Stab1
Name: stabilin 1
Synonyms: MS-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 192187
Homologene: 9035
Syde2
Name: synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
Synonyms: C430017H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 214804
Homologene: 19035
Tmc5
Name: transmembrane channel-like gene family 5
Synonyms: 4932443L08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74424
Homologene: 11713
Gm8909
Name: predicted gene 8909
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 667977
Homologene: 128352
Or1e29
Name: olfactory receptor family 1 subfamily E member 29
Synonyms: GA_x6K02T2P1NL-3932085-3931147, MOR135-6, Olfr389
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 259011
Homologene: 85925
Moxd2
Name: monooxygenase, DBH-like 2
Synonyms: Dbhl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 194357
Homologene: 77226
Pcnx
Name: pecanex homolog
Synonyms: 3526401J03Rik, 2900024E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 54604
VEGA: 12
Homologene: 40997
Sspo
Name: SCO-spondin
Synonyms: C79529, Scospondin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243369
Homologene: 45453
Myh4
Name: myosin, heavy polypeptide 4, skeletal muscle
Synonyms: MyHC-IIb, MHC2B, Myhsf, MM, MYH-2B, Minmus, Minimsc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17884
HGNC: HGNC:7574
Homologene: 123880
Cyp2j6
Name: cytochrome P450, family 2, subfamily j, polypeptide 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13110
HGNC: HGNC:2634
Homologene: 68091
Itgbl1
Name: integrin, beta-like 1
Synonyms: with EGF-like repeat domains, B930011D01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 223272
HGNC: HGNC:6164
Homologene: 3519
Inhca
Name: inhibitor of carbonic anhydrase
Synonyms: mICA, 1300017J02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71775
Homologene: 826
Or2g25
Name: olfactory receptor family 2 subfamily G member 25
Synonyms: GA_x6K02T2PSCP-2119438-2118485, MOR256-33, Olfr117
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258263
Homologene: 105876
Mc2r
Name: melanocortin 2 receptor
Synonyms: adrenocorticotropic hormone receptor, Acthr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17200
VEGA: 18
HGNC: HGNC:6930
Homologene: 444
Gbp2b
Name: guanylate binding protein 2b
Synonyms: Mag-1, Mpa-1, Gbp-1, Mpa1, Gbp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 14468
HGNC: HGNC:4183
Homologene: 137233
Disc1
Name: disrupted in schizophrenia 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244667
HGNC: HGNC:2888
Homologene: 10257
Pccb
Name: propionyl Coenzyme A carboxylase, beta polypeptide
Synonyms: 1300012P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 66904
HGNC: HGNC:8654
Homologene: 447
Sp110
Name: Sp110 nuclear body protein
Synonyms: 52kDa, Ipr1, 5031415C07Rik, 5830484A20Rik, Ifi75
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 109032
HGNC: HGNC:5401
Homologene: 82192
Cd44
Name: CD44 antigen
Synonyms: Ly-24, Pgp-1, HERMES
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12505
HGNC: HGNC:1681
Homologene: 508
Best3
Name: bestrophin 3
Synonyms: mBest4, Vmd2l3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 382427
VEGA: 10
Homologene: 33850
Fut11
Name: fucosyltransferase 11
Synonyms: 3110009G03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 73068
VEGA: 14
Homologene: 18313
Pfkfb3
Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Synonyms: E330010H22Rik, uPFK-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 170768
HGNC: HGNC:8874
Homologene: 88708
Cdk5rap1
Name: CDK5 regulatory subunit associated protein 1
Synonyms: 2310066P17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66971
Homologene: 9502
Reep6
Name: receptor accessory protein 6
Synonyms: Dp1l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70335
Homologene: 133833
Smok2b
Name: sperm motility kinase 2B
Synonyms: LOC236574
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 236574
Homologene: 128738
Gipr
Name: gastric inhibitory polypeptide receptor
Synonyms: LOC381853, LOC232937, glucose-dependent insulinotropic polypeptide receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381853
HGNC: HGNC:4271
Homologene: 20081
Wfikkn2
Name: WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
Synonyms: Gasp1, 2610304F08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 278507
Homologene: 35284
Ptpn20
Name: protein tyrosine phosphatase, non-receptor type 20
Synonyms: typ
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 19256
VEGA: 14
Homologene: 74905
Dnaja4
Name: DnaJ heat shock protein family (Hsp40) member A4
Synonyms: Dj4, 1110021L12Rik, Hsj4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 58233
Homologene: 23110
Gm26919
Name: predicted gene, 26919
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Homologene: 134227
2610203C22Rik
Name: RIKEN cDNA 2610203C22 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 72481
Kat2b-ps
Name: K(lysine) acetyltransferase 2B, pseudogene
Synonyms: P/CAF pseudogene, Pcaf-ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100504388
5830432E09Rik
Name: RIKEN cDNA 5830432E09 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67765
Dnase1l1
Name: deoxyribonuclease 1-like 1
Synonyms: G4.8, Dnl1ll, 2310005K03Rik, Dnase1ll
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 69537
HGNC: HGNC:2957
Homologene: 4896
AC132393.1
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 9,561,626 bp
  • C to G, chromosome 1 at 85,589,118 bp
  • A to G, chromosome 1 at 93,431,114 bp
  • G to T, chromosome 1 at 119,527,371 bp
  • C to A, chromosome 1 at 160,722,239 bp
  • A to G, chromosome 1 at 179,622,813 bp
  • G to A, chromosome 2 at 11,484,014 bp
  • A to G, chromosome 2 at 76,736,360 bp
  • A to C, chromosome 2 at 79,315,629 bp
  • C to T, chromosome 2 at 102,831,354 bp
  • T to A, chromosome 2 at 120,697,019 bp
  • T to C, chromosome 2 at 154,342,395 bp
  • A to G, chromosome 3 at 28,124,582 bp
  • T to A, chromosome 3 at 51,457,285 bp
  • A to T, chromosome 3 at 110,135,329 bp
  • T to C, chromosome 3 at 116,610,298 bp
  • C to T, chromosome 3 at 142,598,254 bp
  • CAGTT to CAGTTAGTT, chromosome 3 at 146,001,408 bp
  • T to A, chromosome 3 at 146,007,126 bp
  • T to C, chromosome 4 at 96,531,699 bp
  • A to G, chromosome 5 at 93,391,726 bp
  • A to C, chromosome 6 at 40,879,336 bp
  • T to C, chromosome 6 at 48,488,471 bp
  • T to A, chromosome 6 at 83,191,639 bp
  • A to T, chromosome 6 at 130,677,670 bp
  • A to G, chromosome 6 at 136,767,035 bp
  • C to T, chromosome 7 at 5,410,667 bp
  • C to A, chromosome 7 at 19,159,764 bp
  • G to A, chromosome 7 at 118,645,386 bp
  • T to C, chromosome 7 at 118,753,877 bp
  • C to T, chromosome 7 at 135,652,049 bp
  • C to A, chromosome 8 at 95,872,323 bp
  • A to C, chromosome 8 at 125,132,160 bp
  • T to C, chromosome 9 at 22,375,044 bp
  • A to G, chromosome 9 at 54,699,739 bp
  • A to T, chromosome 9 at 77,457,458 bp
  • T to C, chromosome 9 at 100,985,243 bp
  • C to T, chromosome 9 at 103,266,221 bp
  • A to G, chromosome 10 at 80,335,175 bp
  • A to T, chromosome 10 at 117,009,002 bp
  • A to T, chromosome 11 at 67,255,409 bp
  • T to C, chromosome 11 at 73,777,258 bp
  • A to T, chromosome 11 at 94,238,347 bp
  • C to A, chromosome 12 at 28,828,856 bp
  • T to C, chromosome 12 at 59,204,699 bp
  • C to A, chromosome 12 at 81,994,939 bp
  • G to A, chromosome 12 at 113,414,427 bp
  • A to G, chromosome 14 at 20,696,161 bp
  • G to A, chromosome 14 at 31,159,304 bp
  • A to T, chromosome 14 at 33,614,441 bp
  • G to A, chromosome 14 at 79,377,415 bp
  • T to A, chromosome 14 at 123,966,739 bp
  • T to G, chromosome 15 at 3,320,140 bp
  • T to C, chromosome 15 at 33,212,862 bp
  • A to C, chromosome 16 at 77,077,119 bp
  • T to A, chromosome 17 at 13,235,124 bp
  • C to A, chromosome 17 at 36,165,416 bp
  • A to T, chromosome 17 at 37,659,721 bp
  • A to G, chromosome 17 at 43,666,930 bp
  • A to T, chromosome 18 at 68,408,203 bp
  • T to C, chromosome 19 at 38,943,745 bp
  • C to T, chromosome X at 74,277,038 bp
  • A to C, chromosome Y at 732,964 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5087 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
042676-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.