Strain Name:
C57BL/6J-MtgxR5096Btlr/Mmmh
Stock Number:
042685-MU
Citation ID:
RRID:MMRRC_042685-MU
Other Names:
R5096 (G1), C57BL/6J-MtgxR5096Btlr
Major Collection:

Gene Information

Fzd9
Name: frizzled class receptor 9
Synonyms: frizzled 9, mfz9, Fz9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 14371
VEGA: 5
HGNC: HGNC:4047
Homologene: 2619
Ntmt1
Name: N-terminal Xaa-Pro-Lys N-methyltransferase 1
Synonyms: Mettl11a, 2610205E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 66617
VEGA: 2
Homologene: 5439
Tbce
Name: tubulin-specific chaperone E
Synonyms: C530005D02Rik, 2610206D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 70430
VEGA: 13
Homologene: 37744
Lcmt1
Name: leucine carboxyl methyltransferase 1
Synonyms: Lcmt, LCMT-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 30949
VEGA: 7
Homologene: 41123
Pkn2
Name: protein kinase N2
Synonyms: PRK2, Stk7, 6030436C20Rik, Prkcl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 109333
VEGA: 3
HGNC: HGNC:9406
Homologene: 2054
Tpr
Name: translocated promoter region, nuclear basket protein
Synonyms: 2610029M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 108989
VEGA: 1
Homologene: 37753
Ap3b1
Name: adaptor-related protein complex 3, beta 1 subunit
Synonyms: Hps2, recombination induced mutation 2, beta3A, rim2, AP-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 11774
VEGA: 13
HGNC: HGNC:566
Homologene: 68125
Smc4
Name: structural maintenance of chromosomes 4
Synonyms: Smc4l1, 2500002A22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 70099
VEGA: 3
Homologene: 4015
Atp9b
Name: ATPase, class II, type 9B
Synonyms: IIb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 50771
VEGA: 18
Homologene: 21915
Acin1
Name: apoptotic chromatin condensation inducer 1
Synonyms: 2610036I19Rik, Acinus, 2610510L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 56215
VEGA: 14
Homologene: 22853
Mmp17
Name: matrix metallopeptidase 17
Synonyms: membrane type-4 matrix metalloproteinase, MT4-MMP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 23948
VEGA: 5
HGNC: HGNC:7163
Homologene: 22669
Scube2
Name: signal peptide, CUB domain, EGF-like 2
Synonyms: 4932442O19Rik, ICRFP703N2430Q5.1, Cegf1, ICRFP703B1614Q5.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 56788
VEGA: 7
Homologene: 36383
Iqsec3
Name: IQ motif and Sec7 domain 3
Synonyms: synarfGEF, BRAG3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 243621
VEGA: 6
Homologene: 46091
Cir1
Name: corepressor interacting with RBPJ, 1
Synonyms: CIR, 1700023B02Rik, 2810021A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 66935
VEGA: 2
Homologene: 3589
Grhl1
Name: grainyhead like transcription factor 1
Synonyms: p61 MGR, p70 MGR, Tcfcp2l2, LBP-32
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 195733
VEGA: 12
Homologene: 32219
Cthrc1
Name: collagen triple helix repeat containing 1
Synonyms: 1110014B07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 68588
VEGA: 15
Homologene: 16320
Adar
Name: adenosine deaminase, RNA-specific
Synonyms: Adar1p110, ADAR1, Adar1p150, mZaADAR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 56417
VEGA: 3
HGNC: HGNC:225
Homologene: 9281
Kbtbd2
Name: kelch repeat and BTB (POZ) domain containing 2
Synonyms: Bklhd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 210973
VEGA: 6
Homologene: 17122
Nos3
Name: nitric oxide synthase 3, endothelial cell
Synonyms: eNOS, ecNOS, Nos-3, 2310065A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 18127
VEGA: 5
HGNC: HGNC:7876
Homologene: 504
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 545370
VEGA: 1
Homologene: 23741
Myo3a
Name: myosin IIIA
Synonyms: 9030416P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 667663
VEGA: 2
HGNC: HGNC:7601
Homologene: 49486
Agl
Name: amylo-1,6-glucosidase, 4-alpha-glucanotransferase
Synonyms: 9630046L06Rik, 1110061O17Rik, 9430004C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 77559
VEGA: 3
HGNC: HGNC:321
Homologene: 536
Gbp5
Name: guanylate binding protein 5
Synonyms: 5330409J06Rik, Gbp5a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229898
VEGA: 3
Homologene: 14183
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241516
VEGA: 2
Homologene: 110349
D930020B18Rik
Name: RIKEN cDNA D930020B18 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216393
VEGA: 10
Homologene: 87610
Lrp4
Name: low density lipoprotein receptor-related protein 4
Synonyms: 6430526J12Rik, Megf7, mdig
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228357
VEGA: 2
HGNC: HGNC:6696
Homologene: 17964
Olfr638
Name: olfactory receptor 638
Synonyms: MOR5-1, GA_x6K02T2PBJ9-6737723-6738670
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 259124
VEGA: 7
Homologene: 133592
Olfr356
Name: olfactory receptor 356
Synonyms: MOR134-1, GA_x6K02T2NLDC-33631647-33632594
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258617
VEGA: 2
Homologene: 85948
Snx19
Name: sorting nexin 19
Synonyms: 3526401K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 102607
VEGA: 9
Homologene: 8846
Sytl2
Name: synaptotagmin-like 2
Synonyms: Slp2-c, Slp2-a, Slp2-b, Slp2, Slp2-d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 83671
VEGA: 7
Homologene: 131343
Wt1
Name: Wilms tumor 1 homolog
Synonyms: Wt-1, D630046I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22431
VEGA: 2
Homologene: 11536
Cep89
Name: centrosomal protein 89
Synonyms: 2610507L03Rik, Ccdc123
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 72140
VEGA: 7
Homologene: 12444
Inpp5e
Name: inositol polyphosphate-5-phosphatase E
Synonyms: 1200002L24Rik, 72kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 64436
VEGA: 2
Homologene: 56863
Fam163b
Name: family with sequence similarity 163, member B
Synonyms: C630035N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 109349
VEGA: 2
Homologene: 106097
Kcnb2
Name: potassium voltage gated channel, Shab-related subfamily, member 2
Synonyms: Kv2.2, 9630047L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 98741
VEGA: 1
HGNC: HGNC:6232
Homologene: 31263
Ica1l
Name: islet cell autoantigen 1-like
Synonyms: 1700030B17Rik, Als2cr15, b2b3465Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 70375
VEGA: 1
Homologene: 16323
Colq
Name: collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 102639719
VEGA: 14
HGNC: HGNC:2226
Skint7
Name: selection and upkeep of intraepithelial T cells 7
Synonyms: C130057D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 328505
VEGA: 4
Homologene: 106613
Olfr52
Name: olfactory receptor 52
Synonyms: IE6, GA_x6K02T2Q125-47650922-47649963, MOR185-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18352
VEGA: 2
Homologene: 105200
Ccdc185
Name: coiled-coil domain containing 185
Synonyms: 4922505E12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 433386
Homologene: 17631
Eif3i
Name: eukaryotic translation initiation factor 3, subunit I
Synonyms: Eif3s2, TRIP-1, 36kDa, D4Ertd632e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 54709
VEGA: 4
HGNC: HGNC:3272
Homologene: 2786
Hspa8
Name: heat shock protein 8
Synonyms: Hsp73, 2410008N15Rik, Hsc73, Hsc71, Hsc70
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 15481
VEGA: 9
HGNC: HGNC:5241
Homologene: 68524
Ifi209
Name: interferon activated gene 209
Synonyms: Ifix, Pyhin1, Pyhin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 236312
VEGA: 1
HGNC: HGNC:5395
Homologene: 115929
Fam114a1
Name: family with sequence similarity 114, member A1
Synonyms: 9130005N14Rik, 1190001N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 68303
VEGA: 5
Homologene: 12259
Tmem221
Name: transmembrane protein 221
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 434325
Homologene: 110174
Speer3
Name: spermatogenesis associated glutamate (E)-rich protein 3
Synonyms: 4933405P08Rik, SPEER-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 71026
VEGA: 5
Homologene: 69402
Tmem92
Name: transmembrane protein 92
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 544806
VEGA: 11
Homologene: 136274
Olfr1184
Name: olfactory receptor 1184
Synonyms: MOR225-3, GA_x6K02T2Q125-49974190-49975125
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258820
VEGA: 2
Homologene: 73980
Gm11131
Name: predicted gene 11131
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
Gm6047
Name: predicted gene 6047
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 606510
Gm26870
Name: predicted gene, 26870
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
Tdpoz2
Name: TD and POZ domain containing 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 399673
VEGA: 3
Homologene: 133956
Fam181b
Name: family with sequence similarity 181, member B
Synonyms: A830059I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 58238
VEGA: 7
Homologene: 32504
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 15,710,844 bp
  • T to C, chromosome 1 at 60,028,154 bp
  • A to G, chromosome 1 at 150,446,202 bp
  • C to A, chromosome 1 at 150,610,669 bp
  • T to A, chromosome 1 at 173,644,734 bp
  • A to G, chromosome 1 at 182,748,789 bp
  • A to T, chromosome 2 at 22,574,242 bp
  • G to T, chromosome 2 at 26,399,525 bp
  • A to G, chromosome 2 at 27,112,749 bp
  • C to T, chromosome 2 at 30,820,556 bp
  • T to C, chromosome 2 at 36,937,803 bp
  • A to G, chromosome 2 at 73,303,761 bp
  • G to A, chromosome 2 at 82,991,116 bp
  • A to G, chromosome 2 at 86,181,932 bp
  • C to T, chromosome 2 at 88,487,302 bp
  • A to G, chromosome 2 at 91,485,792 bp
  • A to G, chromosome 2 at 105,143,125 bp
  • T to A, chromosome 3 at 69,021,279 bp
  • T to A, chromosome 3 at 89,747,291 bp
  • T to C, chromosome 3 at 93,652,512 bp
  • A to G, chromosome 3 at 116,780,995 bp
  • A to G, chromosome 3 at 142,501,361 bp
  • A to C, chromosome 3 at 142,839,331 bp
  • A to G, chromosome 4 at 111,981,955 bp
  • C to T, chromosome 4 at 129,600,444 bp
  • C to G, chromosome 5 at 13,796,380 bp
  • C to T, chromosome 5 at 24,371,957 bp
  • T to A, chromosome 5 at 64,979,891 bp
  • C to A, chromosome 5 at 129,605,563 bp
  • C to T, chromosome 5 at 135,249,859 bp
  • A to G, chromosome 6 at 56,779,275 bp
  • C to T, chromosome 6 at 121,386,698 bp
  • C to A, chromosome 7 at 35,428,356 bp
  • T to A, chromosome 7 at 90,376,082 bp
  • T to G, chromosome 7 at 93,081,245 bp
  • T to C, chromosome 7 at 104,003,460 bp
  • T to C, chromosome 7 at 109,799,244 bp
  • T to G, chromosome 7 at 123,401,468 bp
  • A to G, chromosome 8 at 71,558,709 bp
  • T to C, chromosome 9 at 3,038,157 bp
  • T to A, chromosome 9 at 30,428,786 bp
  • T to C, chromosome 9 at 40,802,901 bp
  • A to T, chromosome 10 at 121,667,804 bp
  • T to C, chromosome 11 at 94,779,036 bp
  • A to T, chromosome 12 at 24,603,050 bp
  • A to T, chromosome 13 at 14,029,405 bp
  • A to G, chromosome 13 at 94,479,849 bp
  • C to T, chromosome 14 at 31,552,954 bp
  • A to C, chromosome 14 at 51,826,118 bp
  • A to T, chromosome 14 at 54,679,222 bp
  • T to A, chromosome 15 at 39,084,420 bp
  • T to A, chromosome 17 at 35,379,713 bp
  • C to T, chromosome 18 at 80,762,184 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5096 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042685-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.