Strain Name:
C57BL/6J-MtgxR5096Btlr/Mmmh
Stock Number:
042685-MU
Citation ID:
RRID:MMRRC_042685-MU
Other Names:
R5096 (G1), C57BL/6J-MtgxR5096Btlr
Major Collection:

Strain Information

Fzd9
Name: frizzled class receptor 9
Synonyms: mfz9, frizzled 9, Fz9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14371
HGNC: HGNC:4047
Homologene: 2619
Ntmt1
Name: N-terminal Xaa-Pro-Lys N-methyltransferase 1
Synonyms: 2610205E22Rik, Mettl11a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66617
Homologene: 5439
Tbce
Name: tubulin-specific chaperone E
Synonyms: 2610206D02Rik, C530005D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 70430
Homologene: 37744
Lcmt1
Name: leucine carboxyl methyltransferase 1
Synonyms: Lcmt, LCMT-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 30949
Homologene: 41123
Pkn2
Name: protein kinase N2
Synonyms: PRK2, 6030436C20Rik, Stk7, Prkcl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 109333
HGNC: HGNC:9406
Homologene: 2054
Tpr
Name: translocated promoter region, nuclear basket protein
Synonyms: 2610029M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 108989
Homologene: 37753
Ap3b1
Name: adaptor-related protein complex 3, beta 1 subunit
Synonyms: rim2, Hps2, recombination induced mutation 2, beta3A, AP-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 11774
VEGA: 13
HGNC: HGNC:566
Homologene: 68125
Smc4
Name: structural maintenance of chromosomes 4
Synonyms: 2500002A22Rik, Smc4l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 70099
Homologene: 4015
Atp9b
Name: ATPase, class II, type 9B
Synonyms: IIb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 50771
VEGA: 18
Homologene: 21915
Acin1
Name: apoptotic chromatin condensation inducer 1
Synonyms: 2610510L13Rik, 2610036I19Rik, Acinus
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 56215
Homologene: 22853
Mmp17
Name: matrix metallopeptidase 17
Synonyms: MT4-MMP, membrane type-4 matrix metalloproteinase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 23948
HGNC: HGNC:7163
Homologene: 22669
Scube2
Name: signal peptide, CUB domain, EGF-like 2
Synonyms: ICRFP703N2430Q5.1, ICRFP703B1614Q5.1, 4932442O19Rik, Cegf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56788
Homologene: 36383
Iqsec3
Name: IQ motif and Sec7 domain 3
Synonyms: BRAG3, synarfGEF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243621
Homologene: 46091
Cir1
Name: corepressor interacting with RBPJ, 1
Synonyms: 2810021A19Rik, CIR, 1700023B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66935
Homologene: 3589
Grhl1
Name: grainyhead like transcription factor 1
Synonyms: p70 MGR, p61 MGR, LBP-32, Tcfcp2l2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 195733
VEGA: 12
Homologene: 32219
Cthrc1
Name: collagen triple helix repeat containing 1
Synonyms: 1110014B07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 68588
Homologene: 16320
Adar
Name: adenosine deaminase, RNA-specific
Synonyms: ADAR1, mZaADAR, Adar1p150, Adar1p110
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 56417
HGNC: HGNC:225
Homologene: 9281
Kbtbd2
Name: kelch repeat and BTB (POZ) domain containing 2
Synonyms: Bklhd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 210973
Homologene: 17122
Nos3
Name: nitric oxide synthase 3, endothelial cell
Synonyms: eNOS, ecNOS, Nos-3, 2310065A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18127
HGNC: HGNC:7876
Homologene: 504
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 545370
Homologene: 23741
Myo3a
Name: myosin IIIA
Synonyms: 9030416P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 667663
HGNC: HGNC:7601
Homologene: 49486
Agl
Name: amylo-1,6-glucosidase, 4-alpha-glucanotransferase
Synonyms: 9430004C13Rik, 9630046L06Rik, 1110061O17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 77559
HGNC: HGNC:321
Homologene: 536
Gbp5
Name: guanylate binding protein 5
Synonyms: 5330409J06Rik, Gbp5a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229898
Homologene: 14183
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241516
Homologene: 110349
D930020B18Rik
Name: RIKEN cDNA D930020B18 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216393
Homologene: 87610
Lrp4
Name: low density lipoprotein receptor-related protein 4
Synonyms: 6430526J12Rik, Megf7, mdig
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228357
HGNC: HGNC:6696
Homologene: 17964
Or51q1c
Name: olfactory receptor family 51 subfamily Q member 1C
Synonyms: GA_x6K02T2PBJ9-6737723-6738670, MOR5-1, Olfr638
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259124
Homologene: 133592
Or1ak2
Name: olfactory receptor family 1 subfamily AK member 2
Synonyms: GA_x6K02T2NLDC-33631647-33632594, MOR134-1, Olfr356
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258617
Homologene: 85948
Snx19
Name: sorting nexin 19
Synonyms: 3526401K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 102607
VEGA: 9
Homologene: 8846
Sytl2
Name: synaptotagmin-like 2
Synonyms: Slp2-a, Slp2, Slp2-d, Slp2-c, Slp2-b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 83671
Homologene: 131343
Wt1
Name: WT1 transcription factor
Synonyms: Wt-1, D630046I19Rik, Wilms tumor 1 homolog
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22431
Homologene: 11536
Cep89
Name: centrosomal protein 89
Synonyms: 2610507L03Rik, Ccdc123
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 72140
Homologene: 12444
Inpp5e
Name: inositol polyphosphate-5-phosphatase E
Synonyms: 1200002L24Rik, 72kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 64436
Homologene: 56863
Fam163b
Name: family with sequence similarity 163, member B
Synonyms: C630035N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 109349
Homologene: 106097
Kcnb2
Name: potassium voltage gated channel, Shab-related subfamily, member 2
Synonyms: Kv2.2, 9630047L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98741
HGNC: HGNC:6232
Homologene: 31263
Ica1l
Name: islet cell autoantigen 1-like
Synonyms: 1700030B17Rik, Als2cr15, b2b3465Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 70375
Homologene: 16323
Colq
Name: collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 382864
HGNC: HGNC:2226
Skint7
Name: selection and upkeep of intraepithelial T cells 7
Synonyms: C130057D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 328505
Homologene: 106613
Or8u8
Name: olfactory receptor family 8 subfamily U member 8
Synonyms: IE6, MOR185-6, GA_x6K02T2Q125-47650922-47649963, Olfr52
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18352
Homologene: 105200
Ccdc185
Name: coiled-coil domain containing 185
Synonyms: 4922505E12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 433386
Homologene: 17631
Eif3i
Name: eukaryotic translation initiation factor 3, subunit I
Synonyms: D4Ertd632e, 36kDa, Eif3s2, TRIP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 54709
HGNC: HGNC:3272
Homologene: 2786
Hspa8
Name: heat shock protein 8
Synonyms: Hsp73, Hsc71, Hsc70, 2410008N15Rik, Hsc73
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 15481
HGNC: HGNC:5241
Homologene: 68524
Ifi209
Name: interferon activated gene 209
Synonyms: Ifix, Pyhin1, Pyhin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 236312
Homologene: 115929
Fam114a1
Name: family with sequence similarity 114, member A1
Synonyms: 1190001N04Rik, 9130005N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 68303
Homologene: 12259
Tmem221
Name: transmembrane protein 221
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 434325
Homologene: 110174
Speer3
Name: spermatogenesis associated glutamate (E)-rich protein 3
Synonyms: SPEER-3, 4933405P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71026
Homologene: 69402
Tmem92
Name: transmembrane protein 92
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 544806
Homologene: 136274
Or4p22
Name: olfactory receptor family 4 subfamily P member 22
Synonyms: GA_x6K02T2Q125-49974190-49975125, MOR225-3, Olfr1184
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258820
Homologene: 73980
Gm11131
Name: predicted gene 11131
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Gm6047
Name: predicted gene 6047
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 606510
Gm26870
Name: predicted gene, 26870
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Tdpoz2
Name: TD and POZ domain containing 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 399673
Homologene: 133956
Fam181b
Name: family with sequence similarity 181, member B
Synonyms: A830059I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 58238
Homologene: 32504
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 15,710,844 bp
  • T to C, chromosome 1 at 60,028,154 bp
  • A to G, chromosome 1 at 150,446,202 bp
  • C to A, chromosome 1 at 150,610,669 bp
  • T to A, chromosome 1 at 173,644,734 bp
  • A to G, chromosome 1 at 182,748,789 bp
  • A to T, chromosome 2 at 22,574,242 bp
  • G to T, chromosome 2 at 26,399,525 bp
  • A to G, chromosome 2 at 27,112,749 bp
  • C to T, chromosome 2 at 30,820,556 bp
  • T to C, chromosome 2 at 36,937,803 bp
  • A to G, chromosome 2 at 73,303,761 bp
  • G to A, chromosome 2 at 82,991,116 bp
  • A to G, chromosome 2 at 86,181,932 bp
  • C to T, chromosome 2 at 88,487,302 bp
  • A to G, chromosome 2 at 91,485,792 bp
  • A to G, chromosome 2 at 105,143,125 bp
  • T to A, chromosome 3 at 69,021,279 bp
  • T to A, chromosome 3 at 89,747,291 bp
  • T to C, chromosome 3 at 93,652,512 bp
  • A to G, chromosome 3 at 116,780,995 bp
  • A to G, chromosome 3 at 142,501,361 bp
  • A to C, chromosome 3 at 142,839,331 bp
  • A to G, chromosome 4 at 111,981,955 bp
  • C to T, chromosome 4 at 129,600,444 bp
  • C to G, chromosome 5 at 13,796,380 bp
  • C to T, chromosome 5 at 24,371,957 bp
  • T to A, chromosome 5 at 64,979,891 bp
  • C to A, chromosome 5 at 129,605,563 bp
  • C to T, chromosome 5 at 135,249,859 bp
  • A to G, chromosome 6 at 56,779,275 bp
  • C to T, chromosome 6 at 121,386,698 bp
  • C to A, chromosome 7 at 35,428,356 bp
  • T to A, chromosome 7 at 90,376,082 bp
  • T to G, chromosome 7 at 93,081,245 bp
  • T to C, chromosome 7 at 104,003,460 bp
  • T to C, chromosome 7 at 109,799,244 bp
  • T to G, chromosome 7 at 123,401,468 bp
  • A to G, chromosome 8 at 71,558,709 bp
  • T to C, chromosome 9 at 3,038,157 bp
  • T to A, chromosome 9 at 30,428,786 bp
  • T to C, chromosome 9 at 40,802,901 bp
  • A to T, chromosome 10 at 121,667,804 bp
  • T to C, chromosome 11 at 94,779,036 bp
  • A to T, chromosome 12 at 24,603,050 bp
  • A to T, chromosome 13 at 14,029,405 bp
  • A to G, chromosome 13 at 94,479,849 bp
  • C to T, chromosome 14 at 31,552,954 bp
  • A to C, chromosome 14 at 51,826,118 bp
  • A to T, chromosome 14 at 54,679,222 bp
  • T to A, chromosome 15 at 39,084,420 bp
  • T to A, chromosome 17 at 35,379,713 bp
  • C to T, chromosome 18 at 80,762,184 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5096 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
042685-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.