Strain Name:
C57BL/6J-MtgxR5098Btlr/Mmmh
Stock Number:
042687-MU
Citation ID:
RRID:MMRRC_042687-MU
Other Names:
R5098 (G1), C57BL/6J-MtgxR5098Btlr
Major Collection:

Gene Information

Map4
Name: microtubule-associated protein 4
Synonyms: MAP 4, Mtap4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17758
HGNC: HGNC:6862
Homologene: 1780
Kat6b
Name: K(lysine) acetyltransferase 6B
Synonyms: qkf, querkopf, Morf, B130044K16Rik, monocytic leukemia, Myst4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 54169
Homologene: 136480
Exoc5
Name: exocyst complex component 5
Synonyms: PRO1912, SEC10, Sec10l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105504
Homologene: 38195
Cdc27
Name: cell division cycle 27
Synonyms: APC3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217232
HGNC: HGNC:1728
Homologene: 960
Rad17
Name: RAD17 checkpoint clamp loader component
Synonyms: MmRad24, 9430035O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 19356
VEGA: 13
HGNC: HGNC:9807
Homologene: 32117
Tmem126b
Name: transmembrane protein 126B
Synonyms: 1110001A23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 68472
Homologene: 10222
Ecpas
Name: Ecm29 proteasome adaptor and scaffold
Synonyms: AI314180
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230249
Homologene: 6056
Capns1
Name: calpain, small subunit 1
Synonyms: Capa-4, Capa4, Capn4, D7Ertd146e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12336
HGNC: HGNC:1481
Homologene: 1327
Cd72
Name: CD72 antigen
Synonyms: Ly-m19, Lyb-2, Ly-32, Ly-19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 12517
HGNC: HGNC:1696
Homologene: 1350
Serf1
Name: small EDRK-rich factor 1
Synonyms: 4F5, m4F5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 20365
Homologene: 49268
Dennd1b
Name: DENN/MADD domain containing 1B
Synonyms: F730008N07Rik, 4632404N19Rik, 4930467M19Rik, 6820401H01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329260
Homologene: 11739
Zc3h18
Name: zinc finger CCCH-type containing 18
Synonyms: 1190001B23Rik, 5830416A07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 76014
Homologene: 44894
Slc39a8
Name: solute carrier family 39 (metal ion transporter), member 8
Synonyms: BIGM103, 4933419D20Rik, ZIP8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67547
Homologene: 11155
Map3k14
Name: mitogen-activated protein kinase kinase kinase 14
Synonyms: Nik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 53859
HGNC: HGNC:6853
Homologene: 2940
Scin
Name: scinderin
Synonyms: adseverin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20259
Homologene: 36296
Olfr720
Name: olfactory receptor 720
Synonyms: GA_x6K02T2PLTE-6544896-6543946, MOR274-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 258387
Homologene: 74036
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 329628
Homologene: 14377
Dclre1b
Name: DNA cross-link repair 1B
Synonyms: mSNM1B, Apollo, SNMIB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 140917
Homologene: 32553
Zfp652
Name: zinc finger protein 652
Synonyms: 9530033F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268469
Homologene: 54768
Trpc3
Name: transient receptor potential cation channel, subfamily C, member 3
Synonyms: Trp3, Trrp3, Trcp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 22065
Homologene: 20708
Dnaaf9
Name: dynein axonemal assembly factor 9
Synonyms: 4930402H24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228602
Homologene: 12623
Lpcat3
Name: lysophosphatidylcholine acyltransferase 3
Synonyms: Grcc3f, Oact5, Mboat5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14792
Homologene: 14678
Kdm1b
Name: lysine (K)-specific demethylase 1B
Synonyms: 4632428N09Rik, Aof1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218214
Homologene: 14695
Abca8b
Name: ATP-binding cassette, sub-family A (ABC1), member 8b
Synonyms: Abca8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 27404
HGNC: HGNC:38
Homologene: 56029
Commd3
Name: COMM domain containing 3
Synonyms: D2Ertd542e, Bup
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12238
Homologene: 15693
Sik2
Name: salt inducible kinase 2
Synonyms: G630080D20Rik, Snf1lk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235344
Homologene: 22875
Gm4787
Name: predicted gene 4787
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 214321
Homologene: 86950
Ugt2b37
Name: UDP glucuronosyltransferase 2 family, polypeptide B37
Synonyms: 0610033E06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 112417
Homologene: 137225
Olfr998
Name: olfactory receptor 998
Synonyms: GA_x6K02T2Q125-47069356-47070300, MOR175-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258428
Homologene: 74236
Mybpc1
Name: myosin binding protein C, slow-type
Synonyms: Slow-type C-protein, 8030451F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 109272
HGNC: HGNC:7549
Homologene: 1846
Dhx58
Name: DEXH (Asp-Glu-X-His) box polypeptide 58
Synonyms: B430001I08Rik, LPG2, D11Lgp2e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 80861
Homologene: 69371
Krtap9-3
Name: keratin associated protein 9-3
Synonyms: 2310040M23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 75586
Homologene: 137392
Slc22a19
Name: solute carrier family 22 (organic anion transporter), member 19
Synonyms: D630043A20Rik, Oat5, Slc22a9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 207151
Homologene: 133125
Ccdc66
Name: coiled-coil domain containing 66
Synonyms: E230015L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 320234
VEGA: 14
Homologene: 35309
Bcl2a1b
Name: B cell leukemia/lymphoma 2 related protein A1b
Synonyms: A1-b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12045
HGNC: HGNC:991
Homologene: 2988
Suox
Name: sulfite oxidase
Synonyms: SO
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 211389
VEGA: 10
Homologene: 394
Vmn1r40
Name: vomeronasal 1 receptor 40
Synonyms: V1rb7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 113855
Homologene: 113975
Cyp2f2
Name: cytochrome P450, family 2, subfamily f, polypeptide 2
Synonyms: Cyp2f
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13107
Homologene: 73898
Card10
Name: caspase recruitment domain family, member 10
Synonyms: CARMA3, Bimp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 105844
Homologene: 8728
Pgap6
Name: post-glycosylphosphatidylinositol attachment to proteins 6
Synonyms: M83, Rxylt1, Tmem8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 60455
Homologene: 10944
Art5
Name: ADP-ribosyltransferase 5
Synonyms: Yac-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11875
Homologene: 7231
Pcdhb20
Name: protocadherin beta 20
Synonyms: Pcdhb14, PcdhbT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93891
HGNC: HGNC:8685
Homologene: 134303
Ppil6
Name: peptidylprolyl isomerase (cyclophilin)-like 6
Synonyms: 2900084F20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 73075
VEGA: 10
Homologene: 52155
Olfr1
Name: olfactory receptor 1
Synonyms: MOR135-13, GA_x6K02T2P1NL-3556334-3555390, I54
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258923
Homologene: 115482
Agxt
Name: alanine-glyoxylate aminotransferase
Synonyms: Agxt1, Agt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 11611
HGNC: HGNC:341
Homologene: 37251
Gpr15
Name: G protein-coupled receptor 15
Synonyms: 4933439K08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 71223
VEGA: 16
HGNC: HGNC:4469
Homologene: 3869
Spint3
Name: serine peptidase inhibitor, Kunitz type, 3
Synonyms: Gm14315
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 629747
Homologene: 136351
Gm3327
Name: predicted gene 3327
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 102635261
Homologene: 128452
Tas2r119
Name: taste receptor, type 2, member 119
Synonyms: mt2r19, Tas2r19, mGR19, T2R19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 57254
Homologene: 10480
Hmga1b
Name: high mobility group AT-hook 1B
Synonyms: Hmgi-rs1, ENSMUSG00000041059, Hmga1-rs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 111241
HGNC: HGNC:5010
Homologene: 128226
Ugt2a2
Name: UDP glucuronosyltransferase 2 family, polypeptide A2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 552899
Homologene: 115736
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 93,137,307 bp
  • T to A, chromosome 1 at 139,133,721 bp
  • A to T, chromosome 2 at 18,674,177 bp
  • A to G, chromosome 2 at 85,590,632 bp
  • A to G, chromosome 2 at 130,798,181 bp
  • A to G, chromosome 2 at 164,569,901 bp
  • G to T, chromosome 3 at 36,662,898 bp
  • T to C, chromosome 3 at 38,888,289 bp
  • A to G, chromosome 3 at 103,809,136 bp
  • C to A, chromosome 3 at 135,858,157 bp
  • C to T, chromosome 4 at 43,452,610 bp
  • T to C, chromosome 4 at 58,877,048 bp
  • T to A, chromosome 5 at 87,242,953 bp
  • T to C, chromosome 5 at 87,464,181 bp
  • T to C, chromosome 6 at 89,714,948 bp
  • A to T, chromosome 6 at 124,700,831 bp
  • A to G, chromosome 7 at 27,129,879 bp
  • G to A, chromosome 7 at 30,190,677 bp
  • A to G, chromosome 7 at 90,469,642 bp
  • A to G, chromosome 7 at 102,097,970 bp
  • A to G, chromosome 8 at 122,386,869 bp
  • T to C, chromosome 9 at 50,995,591 bp
  • T to A, chromosome 9 at 89,199,379 bp
  • T to C, chromosome 9 at 110,026,210 bp
  • A to G, chromosome 10 at 41,490,620 bp
  • T to C, chromosome 10 at 88,546,064 bp
  • A to T, chromosome 10 at 128,671,158 bp
  • AGCGGTCGTAGGC to AGC, chromosome 11 at 73,395,654 bp
  • T to C, chromosome 11 at 95,752,936 bp
  • C to A, chromosome 11 at 99,597,990 bp
  • T to C, chromosome 11 at 100,695,173 bp
  • T to A, chromosome 11 at 103,224,359 bp
  • T to C, chromosome 11 at 104,507,287 bp
  • T to C, chromosome 11 at 109,957,118 bp
  • T to C, chromosome 11 at 120,763,192 bp
  • A to T, chromosome 12 at 40,077,542 bp
  • G to C, chromosome 12 at 81,377,830 bp
  • A to G, chromosome 13 at 47,062,991 bp
  • A to G, chromosome 13 at 100,109,067 bp
  • A to T, chromosome 13 at 100,617,646 bp
  • A to G, chromosome 14 at 14,175,683 bp
  • G to A, chromosome 14 at 21,619,015 bp
  • G to A, chromosome 14 at 27,498,793 bp
  • A to T, chromosome 14 at 44,124,835 bp
  • T to C, chromosome 14 at 49,048,847 bp
  • A to G, chromosome 15 at 32,178,082 bp
  • G to A, chromosome 15 at 78,776,717 bp
  • T to A, chromosome 16 at 58,718,527 bp
  • A to T, chromosome 17 at 26,118,928 bp
  • A to G, chromosome 18 at 37,504,805 bp
  • T to C, chromosome 19 at 7,709,719 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5098 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
042687-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.