Strain Name:
C57BL/6J-MtgxR5183Btlr/Mmmh
Stock Number:
042762-MU
Citation ID:
RRID:MMRRC_042762-MU
Other Names:
R5183 (G1), C57BL/6J-MtgxR5183Btlr
Major Collection:

Gene Information

Slc6a5
Name: solute carrier family 6 (neurotransmitter transporter, glycine), member 5
Synonyms: Glyt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 104245
Homologene: 37901
Galnt10
Name: polypeptide N-acetylgalactosaminyltransferase 10
Synonyms: C330012K04Rik, Galnt9, GalNAc-T10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 171212
Homologene: 14924
Ptprk
Name: protein tyrosine phosphatase, receptor type, K
Synonyms: PTPk, RPTPkappa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 19272
VEGA: 10
HGNC: HGNC:9674
Homologene: 55693
Mthfr
Name: methylenetetrahydrofolate reductase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 17769
HGNC: HGNC:7436
Homologene: 4349
Iqgap1
Name: IQ motif containing GTPase activating protein 1
Synonyms: D7Ertd237e, D7Ertd257e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 29875
HGNC: HGNC:6110
Homologene: 74514
Secisbp2
Name: SECIS binding protein 2
Synonyms: 2210413N07Rik, 2810012K13Rik, SBP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 75420
Homologene: 11415
Ehmt1
Name: euchromatic histone methyltransferase 1
Synonyms: 9230102N17Rik, KMT1D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 77683
Homologene: 11698
Adk
Name: adenosine kinase
Synonyms: AK, 5033405D03Rik, 2310026J05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 11534
VEGA: 14
HGNC: HGNC:257
Homologene: 4891
Shmt1
Name: serine hydroxymethyltransferase 1 (soluble)
Synonyms: mshmt2, Shmt, mshmt1, mshmt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20425
Homologene: 3074
Vps13c
Name: vacuolar protein sorting 13C
Synonyms: C230055H22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 320528
VEGA: 9
Homologene: 41188
Dock6
Name: dedicator of cytokinesis 6
Synonyms: C330023D02Rik, 4931431C02Rik, 2410095B20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 319899
VEGA: 9
Homologene: 83291
Kdm5a
Name: lysine (K)-specific demethylase 5A
Synonyms: Rbbp2, Jarid1a, RBP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 214899
HGNC: HGNC:9886
Homologene: 3419
Msh2
Name: mutS homolog 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 17685
HGNC: HGNC:7325
Homologene: 210
Pan2
Name: PAN2 poly(A) specific ribonuclease subunit
Synonyms: 1200014O24Rik, Usp52
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 103135
VEGA: 10
Homologene: 5918
Orc2
Name: origin recognition complex, subunit 2
Synonyms: Orc2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18393
HGNC: HGNC:8488
Homologene: 4512
Fasn
Name: fatty acid synthase
Synonyms: A630082H08Rik, FAS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14104
HGNC: HGNC:3594
Homologene: 55800
Cdc42bpg
Name: CDC42 binding protein kinase gamma (DMPK-like)
Synonyms: MRCKgamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 240505
Homologene: 28384
Trio
Name: triple functional domain (PTPRF interacting)
Synonyms: Solo, 6720464I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223435
VEGA: 15
Homologene: 20847
Stt3b
Name: STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
Synonyms: Simp, 1300006C19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 68292
VEGA: 9
Homologene: 7387
Cftr
Name: cystic fibrosis transmembrane conductance regulator
Synonyms: Abcc7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 12638
HGNC: HGNC:1884
Homologene: 55465
Robo1
Name: roundabout guidance receptor 1
Synonyms: DUTT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 19876
Homologene: 2206
4930522L14Rik
Name: RIKEN cDNA 4930522L14 gene
Synonyms: Gm42152
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100041734
HGNC: null
Homologene: null
Cdan1
Name: congenital dyserythropoietic anemia, type I (human)
Synonyms: 1500015A01Rik, CDA1, CDA-I, codanin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 68968
HGNC: HGNC:1713
Homologene: 16324
Coq7
Name: demethyl-Q 7
Synonyms: clk-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 12850
HGNC: HGNC:2244
Homologene: 6953
Ncoa2
Name: nuclear receptor coactivator 2
Synonyms: SRC-2, TIF-2, D1Ertd433e, TIF2, Grip1, bHLHe75, glucocorticoid receptor-interacting protein 1, KAT13C, TIF2/GRIP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 17978
HGNC: HGNC:7669
Homologene: 4768
Gps2
Name: G protein pathway suppressor 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 56310
HGNC: HGNC:4550
Homologene: 49599
Cep152
Name: centrosomal protein 152
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 99100
Homologene: 37159
Asxl3
Name: additional sex combs like 3, transcriptional regulator
Synonyms: LOC381127, D430002O22Rik, C230079D11Rik, D930044O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 211961
Homologene: 19371
Moxd1
Name: monooxygenase, DBH-like 1
Synonyms: 3230402N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 59012
Homologene: 22904
Dnhd1
Name: dynein heavy chain domain 1
Synonyms: 8030491N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 77505
Homologene: 131117
Grn
Name: granulin
Synonyms: progranulin, epithelin, PC cell-derived growth factor, Pgrn, acrogranulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14824
HGNC: HGNC:4601
Homologene: 1577
Aqp11
Name: aquaporin 11
Synonyms: sjds, 1700015P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 66333
Homologene: 18269
Prl
Name: prolactin
Synonyms: Prl1a1, Prl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 19109
HGNC: HGNC:9445
Homologene: 732
Abca3
Name: ATP-binding cassette, sub-family A (ABC1), member 3
Synonyms: ABC-C, Abc3, 1810036E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 27410
HGNC: HGNC:33
Homologene: 37437
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Kidins220
Name: kinase D-interacting substrate 220
Synonyms: 3110039L19Rik, C330002I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 77480
VEGA: 12
Homologene: 14254
Fat3
Name: FAT atypical cadherin 3
Synonyms: LOC382129, 9430076A06Rik, LOC234973, D430038H04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 270120
VEGA: 9
Homologene: 82252
Myo1g
Name: myosin IG
Synonyms: E430002D17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 246177
Homologene: 27996
Myo3a
Name: myosin IIIA
Synonyms: 9030416P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 667663
HGNC: HGNC:7601
Homologene: 49486
Pik3r4
Name: phosphoinositide-3-kinase regulatory subunit 4
Synonyms: p150, Vps15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 75669
HGNC: HGNC:8982
Homologene: 24678
Nwd1
Name: NACHT and WD repeat domain containing 1
Synonyms: A230063L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 319555
Homologene: 72261
Man2b1
Name: mannosidase 2, alpha B1
Synonyms: lysosomal alpha-mannosidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 17159
HGNC: HGNC:6826
Homologene: 37322
Trim34b
Name: tripartite motif-containing 34B
Synonyms: Gm15134, Trim34-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 434218
Homologene: 128238
Gm884
Name: predicted gene 884
Synonyms: LOC380730
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 380730
Homologene: 134511
Gpr179
Name: G protein-coupled receptor 179
Synonyms: 5330439C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217143
Homologene: 34917
Htra1
Name: HtrA serine peptidase 1
Synonyms: insulin-like growth factor binding protein 5 protease, RSPP11, L56, HtrA1, Prss11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 56213
HGNC: HGNC:9476
Homologene: 31114
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: MUC5, MUC9, 2300002I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Gatm
Name: glycine amidinotransferase (L-arginine:glycine amidinotransferase)
Synonyms: 1810003P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 67092
HGNC: HGNC:4175
Homologene: 1136
Slc8a3
Name: solute carrier family 8 (sodium/calcium exchanger), member 3
Synonyms: Ncx3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 110893
Homologene: 62645
Itgad
Name: integrin, alpha D
Synonyms: Cd11d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 381924
HGNC: HGNC:6146
Homologene: 56919
Slco1a4
Name: solute carrier organic anion transporter family, member 1a4
Synonyms: Oatp1a4, Oatp2, Slc21a5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 28250
Homologene: 130782
Krt72
Name: keratin 72
Synonyms: Krt72-ps, K6irs2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 105866
Homologene: 25876
Celsr3
Name: cadherin, EGF LAG seven-pass G-type receptor 3
Synonyms: flamingo, Fmi1, Adgrc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 107934
HGNC: HGNC:3230
Homologene: 1077
Zfp108
Name: zinc finger protein 108
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 54678
HGNC: null
Homologene: 117959
Ttc7
Name: tetratricopeptide repeat domain 7
Synonyms: 1700007L07Rik, 1110035E02Rik, fsn, hea
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 225049
Homologene: 12515
Miip
Name: migration and invasion inhibitory protein
Synonyms: D4Wsu114e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 28010
Homologene: 15879
Arhgef40
Name: Rho guanine nucleotide exchange factor (GEF) 40
Synonyms: E130112L23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 268739
Homologene: 19560
Dnase2a
Name: deoxyribonuclease II alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 13423
HGNC: HGNC:2960
Homologene: 68179
Lrmp
Name: lymphoid-restricted membrane protein
Synonyms: D6Int8, Jaw1, D6Int4, D6Int7, D6Int3, D6Int5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16970
HGNC: HGNC:6690
Homologene: 4483
Zfp618
Name: zinc finger protein 618
Synonyms: D430033D05Rik, 2810040O04Rik, 2810031P15Rik, Nedd10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 72701
Homologene: 18975
Icosl
Name: icos ligand
Synonyms: B7h, GL50-B, B7-H2, ICOS-L, B7RP-1, LICOS, GL50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 50723
VEGA: 10
Homologene: 49412
Ufsp2
Name: UFM1-specific peptidase 2
Synonyms: 1810047C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 192169
Homologene: 10151
Mrpl45
Name: mitochondrial ribosomal protein L45
Synonyms: 2600005P05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 67036
Homologene: 32647
Tle6
Name: transducin-like enhancer of split 6
Synonyms: Grg6, 1810057E06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 114606
Homologene: 11701
Gpam
Name: glycerol-3-phosphate acyltransferase, mitochondrial
Synonyms: GPAT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 14732
Homologene: 7343
Slc27a3
Name: solute carrier family 27 (fatty acid transporter), member 3
Synonyms: FATP3, Acsvl3, fatty acid transport protein 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 26568
Homologene: 11529
Oscp1
Name: organic solute carrier partner 1
Synonyms: 6030436A01Rik, 1810007P19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230751
Homologene: 71010
Olfr726
Name: olfactory receptor 726
Synonyms: GA_x6K02T2PMLR-5775299-5774334, MOR246-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 258313
Homologene: 44957
Commd2
Name: COMM domain containing 2
Synonyms: D3Ertd176e, HSPC042, 1190017G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 52245
Homologene: 9381
Rflna
Name: refilin A
Synonyms: Fam101a, cfm2, 3110032G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 73121
Homologene: 18764
Gm6768
Name: predicted gene 6768
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 627557
VEGA: 12
HGNC: null
Homologene: null
Gsg1
Name: germ cell associated 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 14840
Homologene: 7745
Glrp1
Name: glutamine repeat protein 1
Synonyms: GRP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 14659
HGNC: null
Homologene: null
Nme6
Name: NME/NM23 nucleoside diphosphate kinase 6
Synonyms: nm23-M6, non-metastatic cells 6, protein expressed in (nucleoside-diphosphate kinase)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 54369
Homologene: 4231
Gm5455
Name: predicted pseudogene 5455
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 432803
VEGA: 13
HGNC: null
Homologene: null
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to C, chromosome 1 at 13,174,366 bp
  • A to T, chromosome 1 at 58,474,818 bp
  • A to T, chromosome 1 at 88,509,852 bp
  • A to T, chromosome 2 at 22,578,158 bp
  • G to T, chromosome 2 at 24,877,497 bp
  • A to T, chromosome 2 at 76,980,181 bp
  • T to A, chromosome 2 at 120,729,580 bp
  • A to T, chromosome 2 at 122,595,503 bp
  • A to G, chromosome 2 at 125,566,638 bp
  • A to T, chromosome 3 at 57,646,814 bp
  • A to G, chromosome 3 at 90,389,170 bp
  • G to A, chromosome 4 at 63,099,282 bp
  • A to T, chromosome 4 at 126,087,729 bp
  • A to T, chromosome 4 at 147,863,069 bp
  • T to A, chromosome 4 at 148,051,360 bp
  • A to T, chromosome 5 at 109,739,305 bp
  • A to T, chromosome 5 at 125,011,405 bp
  • T to C, chromosome 6 at 18,299,833 bp
  • C to A, chromosome 6 at 120,430,016 bp
  • T to A, chromosome 6 at 135,241,370 bp
  • A to T, chromosome 6 at 141,839,631 bp
  • A to G, chromosome 6 at 145,138,220 bp
  • G to T, chromosome 7 at 24,260,738 bp
  • T to C, chromosome 7 at 49,936,209 bp
  • T to C, chromosome 7 at 80,723,065 bp
  • T to C, chromosome 7 at 97,737,756 bp
  • C to A, chromosome 7 at 104,329,911 bp
  • G to A, chromosome 7 at 105,703,209 bp
  • T to A, chromosome 7 at 118,528,267 bp
  • T to C, chromosome 7 at 128,198,223 bp
  • C to T, chromosome 7 at 130,983,716 bp
  • T to A, chromosome 7 at 141,850,810 bp
  • T to C, chromosome 8 at 45,994,089 bp
  • T to A, chromosome 8 at 72,671,086 bp
  • T to C, chromosome 8 at 84,909,578 bp
  • T to A, chromosome 8 at 85,095,784 bp
  • T to A, chromosome 9 at 15,960,313 bp
  • C to T, chromosome 9 at 21,841,603 bp
  • T to C, chromosome 9 at 67,908,052 bp
  • T to C, chromosome 9 at 105,682,308 bp
  • A to G, chromosome 9 at 108,837,560 bp
  • T to A, chromosome 9 at 109,841,489 bp
  • A to T, chromosome 9 at 115,266,143 bp
  • T to G, chromosome 10 at 24,279,547 bp
  • T to G, chromosome 10 at 24,287,136 bp
  • T to C, chromosome 10 at 28,475,236 bp
  • C to T, chromosome 10 at 78,069,485 bp
  • T to A, chromosome 10 at 81,592,801 bp
  • T to C, chromosome 10 at 128,317,969 bp
  • G to C, chromosome 11 at 6,508,243 bp
  • T to C, chromosome 11 at 57,769,588 bp
  • A to G, chromosome 11 at 60,797,482 bp
  • A to G, chromosome 11 at 69,915,197 bp
  • T to C, chromosome 11 at 97,316,751 bp
  • T to G, chromosome 11 at 97,351,728 bp
  • C to A, chromosome 11 at 102,430,554 bp
  • T to C, chromosome 11 at 103,543,121 bp
  • T to C, chromosome 11 at 120,808,882 bp
  • T to C, chromosome 12 at 25,051,126 bp
  • A to G, chromosome 12 at 81,314,491 bp
  • A to C, chromosome 12 at 119,261,288 bp
  • T to C, chromosome 13 at 27,057,596 bp
  • T to C, chromosome 13 at 51,665,424 bp
  • T to A, chromosome 13 at 110,305,428 bp
  • A to G, chromosome 14 at 21,240,531 bp
  • A to C, chromosome 14 at 50,084,546 bp
  • T to C, chromosome 14 at 52,004,099 bp
  • C to A, chromosome 15 at 27,902,600 bp
  • T to G, chromosome 15 at 101,776,725 bp
  • T to C, chromosome 16 at 72,742,150 bp
  • T to G, chromosome 17 at 24,374,453 bp
  • A to T, chromosome 17 at 87,292,878 bp
  • C to A, chromosome 17 at 87,723,413 bp
  • C to G, chromosome 18 at 22,525,299 bp
  • A to G, chromosome 19 at 6,321,805 bp
  • C to T, chromosome 19 at 55,083,227 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5183 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042762-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.