Strain Name:
C57BL/6J-MtgxR5197Btlr/Mmmh
Stock Number:
042773-MU
Citation ID:
RRID:MMRRC_042773-MU
Other Names:
R5197 (G1), C57BL/6J-MtgxR5197Btlr
Major Collection:

Gene Information

Vps33a
Name: VPS33A CORVET/HOPS core subunit
Synonyms: bf, 3830421M04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 77573
Homologene: 11294
Htr3b
Name: 5-hydroxytryptamine (serotonin) receptor 3B
Synonyms: 5-HT3B, 5-HT3 receptor subunit B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 57014
VEGA: 9
HGNC: HGNC:5298
Homologene: 38131
Slc1a2
Name: solute carrier family 1 (glial high affinity glutamate transporter), member 2
Synonyms: MGLT1, 2900019G14Rik, GLT-1, 1700091C19Rik, Eaat2, GLT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20511
Homologene: 3075
Sash1
Name: SAM and SH3 domain containing 1
Synonyms: A330076K04Rik, 1100001C18Rik, 2500002E12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 70097
Homologene: 69182
Ppp1r9a
Name: protein phosphatase 1, regulatory subunit 9A
Synonyms: 4930518N04Rik, neurabin-I, A230094E16Rik, Neurabin I, NRB, 2810430P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 243725
Homologene: 14247
Eps8
Name: epidermal growth factor receptor pathway substrate 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 13860
HGNC: HGNC:3420
Homologene: 3272
Psmd13
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
Synonyms: S11, 26S proteasome subunit p40.5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 23997
HGNC: HGNC:9558
Homologene: 2110
Mgll
Name: monoglyceride lipase
Synonyms: Magl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 23945
Homologene: 38298
Cyp39a1
Name: cytochrome P450, family 39, subfamily a, polypeptide 1
Synonyms: oxysterol 7-alpha-hydroxylase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 56050
VEGA: 17
Homologene: 9580
Pard3
Name: par-3 family cell polarity regulator
Synonyms: Pard3a, PAR-3, Par3, ASIP, D8Ertd580e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 93742
Homologene: 10489
Mob2
Name: MOB kinase activator 2
Synonyms: 2700078K21Rik, 1110017M21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 101513
Homologene: 12477
Anln
Name: anillin, actin binding protein
Synonyms: Scraps, 1110037A17Rik, 2900037I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 68743
VEGA: 9
Homologene: 41281
Wdr7
Name: WD repeat domain 7
Synonyms: TGF-beta resistance associated gene, TRAG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 104082
VEGA: 18
Homologene: 11408
Srrm2
Name: serine/arginine repetitive matrix 2
Synonyms: 5033413A03Rik, SRm300
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 75956
Herc1
Name: HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Synonyms: D130015N03Rik, 2810449H11Rik, tbl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235439
HGNC: HGNC:4867
Homologene: 31207
Brpf1
Name: bromodomain and PHD finger containing, 1
Synonyms: 4833438B11Rik, 4930540D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 78783
Homologene: 31251
Ttk
Name: Ttk protein kinase
Synonyms: Esk1, Mps1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 22137
Homologene: 2489
Tmprss6
Name: transmembrane serine protease 6
Synonyms: matriptase-2, 1300008A22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 71753
VEGA: 15
Homologene: 12408
Aldh4a1
Name: aldehyde dehydrogenase 4 family, member A1
Synonyms: Ahd-1, Ssdh1, P5CDH, A930035F14Rik, ALDH4, Ahd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 212647
HGNC: HGNC:406
Homologene: 6081
Tram1
Name: translocating chain-associating membrane protein 1
Synonyms: TRAMP, 1810049E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 72265
Homologene: 8621
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 20191
VEGA: 13
Homologene: 37423
Afg3l2
Name: AFG3-like AAA ATPase 2
Synonyms: 2310036I02Rik, Emv66, par
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 69597
VEGA: 18
HGNC: HGNC:315
Homologene: 4947
Ift74
Name: intraflagellar transport 74
Synonyms: 1700029H06Rik, Cmg1, b2b796Clo, Ccdc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 67694
Homologene: 11831
Cftr
Name: cystic fibrosis transmembrane conductance regulator
Synonyms: Abcc7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 12638
HGNC: HGNC:1884
Homologene: 55465
Prkcq
Name: protein kinase C, theta
Synonyms: Pkcq, PKCtheta, PKC theta, PKC-0, A130035A12Rik, PKC-theta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18761
HGNC: HGNC:9410
Homologene: 21263
Lipc
Name: lipase, hepatic
Synonyms: Hpl, HL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 15450
VEGA: 9
HGNC: HGNC:6619
Homologene: 199
Ubr4
Name: ubiquitin protein ligase E3 component n-recognin 4
Synonyms: p600, A930005E13Rik, 1810009A16Rik, LOC381562, D930005K06Rik, Zubr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 69116
Homologene: 10804
Adgra3
Name: adhesion G protein-coupled receptor A3
Synonyms: Gpr125, 3830613O22Rik, Tem5-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 70693
Homologene: 19235
Lgr6
Name: leucine-rich repeat-containing G protein-coupled receptor 6
Synonyms: A530037C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 329252
Homologene: 49680
Lrrc4
Name: leucine rich repeat containing 4
Synonyms: NGL-2, NGL2, Nag14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 192198
Homologene: 36403
Zfp54
Name: zinc finger protein 54
Synonyms: clone 18, Zfp-54, KRAB10, Zfp76
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 22712
Homologene: 129791
Tapt1
Name: transmembrane anterior posterior transformation 1
Synonyms: 4932414K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231225
Homologene: 80206
Zdhhc11
Name: zinc finger, DHHC domain containing 11
Synonyms: 4933421L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 71164
VEGA: 13
Homologene: 128723
Rag2
Name: recombination activating gene 2
Synonyms: Rag-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 19374
HGNC: HGNC:9832
Homologene: 7507
Mfsd14a
Name: major facilitator superfamily domain containing 14A
Synonyms: Hiat1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 15247
Homologene: 22456
Fshb
Name: follicle stimulating hormone beta
Synonyms: FSH, Fshbeta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 14308
HGNC: HGNC:3964
Homologene: 430
Col5a2
Name: collagen, type V, alpha 2
Synonyms: 1110014L14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12832
HGNC: HGNC:2210
Homologene: 20119
Aste1
Name: asteroid homolog 1
Synonyms: 1100001A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 66595
Homologene: 130666
Sugct
Name: succinyl-CoA glutarate-CoA transferase
Synonyms: 5033411D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 192136
VEGA: 13
Homologene: 11681
Nckap5
Name: NCK-associated protein 5
Synonyms: E030049G20Rik, D130011D22Rik, LOC380609
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 210356
Homologene: 35542
Cyp2d41-ps
Name: cytochrome P450, family 2, subfamily d, member 41, pseudogene
Synonyms: Gm5062
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 271300
Olfr1477
Name: olfactory receptor 1477
Synonyms: GA_x6K02T2RE5P-3834960-3835907, MOR202-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258691
Homologene: 110492
Tdrd7
Name: tudor domain containing 7
Synonyms: 5730495N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100121
Homologene: 8618
Ngef
Name: neuronal guanine nucleotide exchange factor
Synonyms: Tims2, ephexin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 53972
HGNC: HGNC:7807
Homologene: 75120
Col22a1
Name: collagen, type XXII, alpha 1
Synonyms: C80743, 2310067L16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 69700
Homologene: 43567
Rufy4
Name: RUN and FYVE domain containing 4
Synonyms: F930048N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 435626
Homologene: 52359
Gm13089
Name: predicted gene 13089
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 277667
Sun1
Name: Sad1 and UNC84 domain containing 1
Synonyms: 4632417G13Rik, Unc84a, 5730434D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 77053
Homologene: 11544
Olfr593
Name: olfactory receptor 593
Synonyms: GA_x6K02T2PBJ9-5927412-5928362, MOR24-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258378
Homologene: 27147
Kif21b
Name: kinesin family member 21B
Synonyms: 2610511N21Rik, N-5 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 16565
Homologene: 56868
Catsper3
Name: cation channel, sperm associated 3
Synonyms: 4921522D01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 76856
Homologene: 12658
Btbd2
Name: BTB (POZ) domain containing 2
Synonyms: 4930512K17Rik, 2610037C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 208198
Homologene: 32365
Pgm2
Name: phosphoglucomutase 2
Synonyms: 3230402E02Rik, Pgm1, Pgm-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 66681
HGNC: HGNC:8906
Homologene: 6693
Cfap43
Name: cilia and flagella associated protein 43
Synonyms: 4930428C11Rik, Wdr96, D19Ertd652e, 4930463G05Rik, 4632415N18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 100048534
Homologene: 36425
Olfr31
Name: olfactory receptor 31
Synonyms: MTPCR53, GA_x6K02T2PLTE-6714644-6715597, MOR274-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 18330
HGNC: HGNC:8277
Homologene: 74028
Elmo1
Name: engulfment and cell motility 1
Synonyms: 6330578D22Rik, C230095H21Rik, CED-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 140580
Homologene: 56685
Acsbg1
Name: acyl-CoA synthetase bubblegum family member 1
Synonyms: Bgm, E230019G03Rik, Lpd, BG1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 94180
Homologene: 9044
Fam71f2
Name: family with sequence similarity 71, member F2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 245884
Homologene: 52974
Lrrc63
Name: leucine rich repeat containing 63
Synonyms: 4921509B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 70859
Homologene: 52823
Zfp647
Name: zinc finger protein 647
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239546
VEGA: 15
Homologene: 27805
Xrcc2
Name: X-ray repair complementing defective repair in Chinese hamster cells 2
Synonyms: RecA, 8030409M04Rik, 4921524O04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 57434
Homologene: 3964
Rab3gap1
Name: RAB3 GTPase activating protein subunit 1
Synonyms: 1700003B17Rik, p130, 4732493F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226407
Homologene: 45617
Olfr1
Name: olfactory receptor 1
Synonyms: I54, MOR135-13, GA_x6K02T2P1NL-3556334-3555390
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 258923
Homologene: 115482
Sike1
Name: suppressor of IKBKE 1
Synonyms: 5730470L24Rik, 2810005O12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 66641
Homologene: 32622
Atp6v0e2
Name: ATPase, H+ transporting, lysosomal V0 subunit E2
Synonyms: 0610006O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 76252
Homologene: 44221
Olfr1000
Name: olfactory receptor 1000
Synonyms: GA_x6K02T2Q125-47087719-47086775, MOR175-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 257899
Rnase6
Name: ribonuclease, RNase A family, 6
Synonyms: 9530043P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 78416
VEGA: 14
Homologene: 4102
Gm4705
Name: predicted gene 4705
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 100043876
Homologene: 105146
CR974439.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
Hist1h3d
Name: histone cluster 1, H3d
Synonyms: H3-b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 319149
HGNC: HGNC:4766
Homologene: 134332
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 13,571,902 bp
  • G to T, chromosome 1 at 45,393,081 bp
  • T to C, chromosome 1 at 74,147,663 bp
  • C to A, chromosome 1 at 87,509,368 bp
  • T to A, chromosome 1 at 126,222,673 bp
  • T to A, chromosome 1 at 127,889,194 bp
  • C to T, chromosome 1 at 134,994,010 bp
  • A to T, chromosome 1 at 136,144,625 bp
  • C to T, chromosome 2 at 11,299,416 bp
  • T to C, chromosome 2 at 85,608,447 bp
  • C to A, chromosome 2 at 101,630,740 bp
  • A to G, chromosome 2 at 102,756,115 bp
  • T to C, chromosome 2 at 107,057,509 bp
  • T to C, chromosome 3 at 102,997,239 bp
  • A to T, chromosome 3 at 116,648,501 bp
  • T to C, chromosome 4 at 46,034,350 bp
  • T to A, chromosome 4 at 94,662,596 bp
  • A to G, chromosome 4 at 139,468,097 bp
  • A to C, chromosome 4 at 139,648,301 bp
  • A to C, chromosome 4 at 143,698,062 bp
  • G to T, chromosome 5 at 25,692,658 bp
  • G to A, chromosome 5 at 44,194,374 bp
  • A to G, chromosome 5 at 49,960,754 bp
  • C to T, chromosome 5 at 64,105,832 bp
  • A to T, chromosome 5 at 123,563,410 bp
  • A to G, chromosome 5 at 139,226,881 bp
  • T to A, chromosome 6 at 5,156,177 bp
  • T to C, chromosome 6 at 18,255,414 bp
  • G to T, chromosome 6 at 28,830,143 bp
  • G to T, chromosome 6 at 29,281,222 bp
  • G to A, chromosome 6 at 48,540,117 bp
  • A to G, chromosome 6 at 88,766,281 bp
  • A to G, chromosome 6 at 113,319,941 bp
  • C to A, chromosome 6 at 137,490,290 bp
  • T to C, chromosome 6 at 137,490,291 bp
  • G to A, chromosome 7 at 103,212,000 bp
  • T to A, chromosome 7 at 140,894,461 bp
  • T to C, chromosome 7 at 142,009,537 bp
  • A to G, chromosome 8 at 127,073,290 bp
  • A to T, chromosome 9 at 22,352,781 bp
  • T to C, chromosome 9 at 48,945,515 bp
  • T to C, chromosome 9 at 54,622,582 bp
  • C to A, chromosome 9 at 66,448,504 bp
  • T to A, chromosome 9 at 70,798,391 bp
  • T to C, chromosome 9 at 83,839,341 bp
  • T to C, chromosome 9 at 105,405,054 bp
  • T to G, chromosome 10 at 8,740,225 bp
  • T to C, chromosome 10 at 80,646,419 bp
  • AGCGGTCGTAGGC to AGC, chromosome 11 at 73,395,654 bp
  • A to T, chromosome 13 at 11,638,430 bp
  • C to T, chromosome 13 at 17,323,276 bp
  • T to G, chromosome 13 at 20,564,437 bp
  • T to A, chromosome 13 at 23,576,130 bp
  • T to C, chromosome 13 at 55,808,176 bp
  • A to G, chromosome 13 at 73,965,569 bp
  • T to A, chromosome 14 at 14,328,462 bp
  • A to G, chromosome 14 at 51,130,213 bp
  • T to A, chromosome 14 at 75,084,882 bp
  • C to T, chromosome 15 at 72,009,406 bp
  • G to A, chromosome 15 at 76,912,085 bp
  • T to A, chromosome 15 at 78,454,189 bp
  • A to G, chromosome 15 at 82,778,780 bp
  • C to T, chromosome 17 at 21,434,180 bp
  • T to C, chromosome 17 at 23,817,384 bp
  • T to G, chromosome 17 at 37,575,220 bp
  • T to G, chromosome 17 at 43,746,538 bp
  • C to G, chromosome 17 at 66,413,819 bp
  • A to G, chromosome 18 at 63,738,866 bp
  • G to T, chromosome 18 at 67,421,259 bp
  • G to T, chromosome 19 at 13,502,384 bp
  • A to G, chromosome 19 at 47,897,372 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5197 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042773-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.