Strain Name:
C57BL/6J-MtgxR5208Btlr/Mmmh
Stock Number:
042783-MU
Citation ID:
RRID:MMRRC_042783-MU
Other Names:
R5208 (G1), C57BL/6J-MtgxR5208Btlr
Major Collection:

Gene Information

Sp4
Name: trans-acting transcription factor 4
Synonyms: HF1-b, 5730497N03Rik, HF-1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 20688
VEGA: 12
Homologene: 2341
Cadps
Name: Ca2+-dependent secretion activator
Synonyms: CAPS1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 27062
VEGA: 14
HGNC: HGNC:1426
Homologene: 2755
Bmp6
Name: bone morphogenetic protein 6
Synonyms: D13Wsu115e, Vgr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 12161
VEGA: 13
HGNC: HGNC:1073
Homologene: 1300
Met
Name: met proto-oncogene
Synonyms: Par4, c-Met, HGF receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 17295
HGNC: HGNC:7029
Homologene: 206
Mga
Name: MAX gene associated
Synonyms: Mga, Mad5, C130042M01Rik, D030062C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 29808
Homologene: 49351
Lars
Name: leucyl-tRNA synthetase
Synonyms: 2310045K21Rik, 3110009L02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 107045
VEGA: 18
HGNC: HGNC:6512
Homologene: 7083
Ehmt1
Name: euchromatic histone methyltransferase 1
Synonyms: 9230102N17Rik, KMT1D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 77683
Homologene: 11698
Cdk18
Name: cyclin-dependent kinase 18
Synonyms: Pctk3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18557
HGNC: HGNC:8751
Homologene: 1949
Aplf
Name: aprataxin and PNKP like factor
Synonyms: 2010301N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 72103
Homologene: 49753
Zfat
Name: zinc finger and AT hook domain containing
Synonyms: Zfat1, Zfp406, LOC380993
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 380993
Homologene: 16829
Setx
Name: senataxin
Synonyms: A930037J23Rik, Als4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 269254
HGNC: HGNC:445
Homologene: 41003
Tars2
Name: threonyl-tRNA synthetase 2, mitochondrial (putative)
Synonyms: Tarsl1, 2610024N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 71807
Homologene: 23520
Psmd14
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
Synonyms: Pad1, 3200001M20Rik, POH1, 2610312C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 59029
Homologene: 4240
Caprin1
Name: cell cycle associated protein 1
Synonyms: Gpiap1, MMGPIP137, RNG105, caprin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 53872
HGNC: HGNC:6743
Homologene: 4310
Zwilch
Name: zwilch kinetochore protein
Synonyms: 2310031L18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 68014
Homologene: 32381
Eftud2
Name: elongation factor Tu GTP binding domain containing 2
Synonyms: U5-116kD, 116kDa, Snrp116
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20624
Homologene: 3133
Cenpf
Name: centromere protein F
Synonyms: 6530404A22Rik, mitosin, Lek1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 108000
HGNC: HGNC:1857
Homologene: 22969
Ank3
Name: ankyrin 3, epithelial
Synonyms: Ank-3, AnkG, Ankyrin-G, Ankyrin-3, 2900054D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 11735
HGNC: HGNC:494
Homologene: 56908
Ttc37
Name: tetratricopeptide repeat domain 37
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218343
VEGA: 13
Homologene: 40966
Cdc42bpg
Name: CDC42 binding protein kinase gamma (DMPK-like)
Synonyms: MRCKgamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 240505
Homologene: 28384
Akt2
Name: thymoma viral proto-oncogene 2
Synonyms: PKBbeta, 2410016A19Rik, PKB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11652
HGNC: HGNC:392
Homologene: 48773
Chn2
Name: chimerin 2
Synonyms: 4930557O16Rik, 1700026N20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 69993
HGNC: HGNC:1944
Homologene: 31213
Dars2
Name: aspartyl-tRNA synthetase 2 (mitochondrial)
Synonyms: 5830468K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226539
Homologene: 7093
Map3k14
Name: mitogen-activated protein kinase kinase kinase 14
Synonyms: Nik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 53859
HGNC: HGNC:6853
Homologene: 2940
Chrdl2
Name: chordin-like 2
Synonyms: Chl2, 1810022C01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 69121
Homologene: 128795
Adgra3
Name: adhesion G protein-coupled receptor A3
Synonyms: Gpr125, 3830613O22Rik, Tem5-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 70693
Homologene: 19235
Inpp5b
Name: inositol polyphosphate-5-phosphatase B
Synonyms: 75kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 16330
HGNC: HGNC:6077
Homologene: 69021
Zfp142
Name: zinc finger protein 142
Synonyms: 9330177B18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 77264
Homologene: 3723
Ttc13
Name: tetratricopeptide repeat domain 13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234875
Homologene: 11569
Tnks1bp1
Name: tankyrase 1 binding protein 1
Synonyms: TAB182
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228140
Homologene: 14117
Pde4a
Name: phosphodiesterase 4A, cAMP specific
Synonyms: Dpde2, D9Ertd60e, dunce
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 18577
HGNC: HGNC:8780
Homologene: 4520
Asic4
Name: acid-sensing (proton-gated) ion channel family member 4
Synonyms: Accn4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241118
Homologene: 11166
Pex2
Name: peroxisomal biogenesis factor 2
Synonyms: D3Ertd138e, Pxmp3, PMP35, Zellweger syndrome homolog
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 19302
HGNC: HGNC:9717
Homologene: 269
Hormad1
Name: HORMA domain containing 1
Synonyms: Nohma, 4921522K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 67981
Homologene: 69415
Dnah2
Name: dynein, axonemal, heavy chain 2
Synonyms: 2900022L05Rik, Dnahc2, D330014H01Rik, Dnhd3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 327954
HGNC: HGNC:2948
Homologene: 72110
Dnah3
Name: dynein, axonemal, heavy chain 3
Synonyms: Dnahc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 381917
HGNC: HGNC:2949
Homologene: 19674
Lonp1
Name: lon peptidase 1, mitochondrial
Synonyms: LON, 1200017E13Rik, Prss15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 74142
VEGA: 17
HGNC: HGNC:9479
Homologene: 3521
BC024139
Name: cDNA sequence BC024139
Synonyms: 6230424I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 271278
Homologene: 129974
Col6a3
Name: collagen, type VI, alpha 3
Synonyms: Col6a-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12835
HGNC: HGNC:2213
Homologene: 37917
5830411N06Rik
Name: RIKEN cDNA 5830411N06 gene
Synonyms: Scart2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 244234
Homologene: 133218
Gdpd4
Name: glycerophosphodiester phosphodiesterase domain containing 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233537
Homologene: 18606
Aadacl4
Name: arylacetamide deacetylase like 4
Synonyms: Gm13177
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 435815
Homologene: 82530
Slc20a1
Name: solute carrier family 20, member 1
Synonyms: Glvr1, PiT-1, Glvr-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20515
Homologene: 38049
Mybph
Name: myosin binding protein H
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 53311
HGNC: HGNC:7552
Homologene: 3661
Ptprn2
Name: protein tyrosine phosphatase, receptor type, N polypeptide 2
Synonyms: phogrin, PTP-NP, IA-2 beta, 4930425H11Rik, IA-2beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 19276
HGNC: HGNC:9677
Homologene: 2134
Mthfsd
Name: methenyltetrahydrofolate synthetase domain containing
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234814
Homologene: 11245
Pfkfb4
Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 270198
HGNC: HGNC:8875
Homologene: 48288
Disp2
Name: dispatched RND tramsporter family member 2
Synonyms: DispB, B230210L08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 214240
Homologene: 24916
Kcnk4
Name: potassium channel, subfamily K, member 4
Synonyms: TRAAKt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 16528
VEGA: 19
HGNC: HGNC:6279
Homologene: 7391
Fam20c
Name: family with sequence similarity 20, member C
Synonyms: DMP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 80752
Homologene: 56879
Mpl
Name: myeloproliferative leukemia virus oncogene
Synonyms: c-mpl-I, CD110, thrombopoietin receptor, c-mpl, hlb219, c-mpl-II, TPO-R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 17480
HGNC: HGNC:7217
Homologene: 7845
Alcam
Name: activated leukocyte cell adhesion molecule
Synonyms: BEN, SC1, CD166, DM-GRASP, MuSC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 11658
HGNC: HGNC:400
Homologene: 1229
Olfr1278
Name: olfactory receptor 1278
Synonyms: MOR245-11, GA_x6K02T2Q125-72343713-72344654
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258389
Homologene: 74061
Bbs12
Name: Bardet-Biedl syndrome 12 (human)
Synonyms: LOC386537, LOC241950, LOC241950
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 241950
Homologene: 17634
Stt3a
Name: STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)
Synonyms: Itm1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 16430
HGNC: HGNC:6172
Homologene: 40617
Tmem129
Name: transmembrane protein 129
Synonyms: 2410015J15Rik, 0610039G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 68366
Homologene: 44528
Sema4c
Name: sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
Synonyms: Semacl1, Semacl1, Semai, Semaf, M-Sema F
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 20353
Homologene: 23047
Tmem200a
Name: transmembrane protein 200A
Synonyms: C030003D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 77220
VEGA: 10
Homologene: 14175
Olfr988
Name: olfactory receptor 988
Synonyms: GA_x6K02T2Q125-46830591-46829662, MOR203-5P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258166
Homologene: 103791
Tll1
Name: tolloid-like
Synonyms: Tll-1, b2b2476Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 21892
Homologene: 49202
Cfhr1
Name: complement factor H-related 1
Synonyms: Cfhl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 50702
HGNC: HGNC:4888
Homologene: 55632
Psg25
Name: pregnancy-specific glycoprotein 25
Synonyms: cea13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 114868
Homologene: 110989
Spaca7
Name: sperm acrosome associated 7
Synonyms: 1700094C09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 78634
Homologene: 49754
Mup4
Name: major urinary protein 4
Synonyms: Mup-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 17843
Homologene: 74304
Olfr668
Name: olfactory receptor 668
Synonyms: GA_x6K02T2PBJ9-7554614-7553658, MOR34-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 259061
Homologene: 64947
Efcab8
Name: EF-hand calcium binding domain 8
Synonyms: EG329541
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 100504221
Gulp1
Name: GULP, engulfment adaptor PTB domain containing 1
Synonyms: 3110030A04Rik, GULP, Ced6, 5730529O06Rik, CED-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 70676
Homologene: 9467
Gm8674
Name: predicted gene 8674
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 667507
VEGA: 13
Homologene: 140547
Gm7356
Name: predicted gene 7356
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 664821
Homologene: 133217
Prl4a1
Name: prolactin family 4, subfamily a, member 1
Synonyms: PLP-A, Prlpa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 19110
Homologene: 7900
Arl4a
Name: ADP-ribosylation factor-like 4A
Synonyms: Arl4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 11861
HGNC: HGNC:695
Homologene: 4194
Gm26735
Name: predicted gene, 26735
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 36,550,326 bp
  • T to G, chromosome 1 at 44,781,039 bp
  • A to T, chromosome 1 at 74,570,868 bp
  • A to G, chromosome 1 at 75,451,226 bp
  • G to C, chromosome 1 at 90,801,531 bp
  • A to T, chromosome 1 at 132,117,480 bp
  • T to A, chromosome 1 at 134,193,535 bp
  • A to T, chromosome 1 at 139,556,330 bp
  • A to G, chromosome 1 at 161,062,769 bp
  • A to T, chromosome 1 at 189,671,046 bp
  • A to C, chromosome 2 at 24,801,533 bp
  • A to T, chromosome 2 at 29,166,367 bp
  • G to A, chromosome 2 at 61,711,821 bp
  • T to C, chromosome 2 at 85,070,632 bp
  • T to A, chromosome 2 at 85,353,798 bp
  • A to C, chromosome 2 at 103,769,433 bp
  • A to T, chromosome 2 at 111,292,601 bp
  • G to T, chromosome 2 at 118,791,805 bp
  • T to G, chromosome 2 at 119,947,981 bp
  • T to G, chromosome 2 at 129,199,681 bp
  • T to A, chromosome 2 at 153,802,423 bp
  • C to T, chromosome 3 at 5,561,368 bp
  • T to C, chromosome 3 at 37,320,273 bp
  • T to C, chromosome 3 at 95,578,107 bp
  • A to G, chromosome 3 at 95,747,593 bp
  • A to G, chromosome 4 at 59,958,119 bp
  • T to G, chromosome 4 at 118,455,881 bp
  • G to A, chromosome 4 at 124,751,317 bp
  • A to T, chromosome 4 at 144,617,828 bp
  • A to T, chromosome 5 at 33,655,506 bp
  • T to C, chromosome 5 at 50,011,515 bp
  • T to C, chromosome 5 at 138,758,022 bp
  • T to A, chromosome 6 at 17,526,423 bp
  • A to T, chromosome 6 at 54,295,801 bp
  • G to T, chromosome 6 at 87,642,026 bp
  • A to T, chromosome 7 at 18,526,535 bp
  • G to A, chromosome 7 at 27,634,720 bp
  • A to C, chromosome 7 at 98,014,911 bp
  • A to G, chromosome 7 at 100,023,922 bp
  • A to G, chromosome 7 at 104,925,726 bp
  • C to G, chromosome 7 at 120,032,638 bp
  • C to A, chromosome 7 at 140,298,036 bp
  • A to G, chromosome 8 at 12,586,456 bp
  • G to A, chromosome 8 at 64,051,493 bp
  • G to A, chromosome 8 at 121,108,319 bp
  • G to A, chromosome 8 at 124,674,421 bp
  • T to C, chromosome 9 at 21,203,558 bp
  • T to G, chromosome 9 at 36,746,595 bp
  • T to C, chromosome 9 at 64,152,923 bp
  • T to C, chromosome 9 at 109,010,452 bp
  • T to A, chromosome 10 at 25,994,153 bp
  • G to A, chromosome 10 at 70,002,565 bp
  • C to T, chromosome 11 at 69,458,920 bp
  • G to A, chromosome 11 at 102,841,185 bp
  • A to T, chromosome 11 at 103,239,146 bp
  • A to T, chromosome 12 at 40,036,745 bp
  • A to G, chromosome 12 at 116,858,928 bp
  • A to G, chromosome 12 at 118,299,546 bp
  • T to C, chromosome 13 at 28,018,484 bp
  • C to A, chromosome 13 at 28,950,938 bp
  • G to A, chromosome 13 at 38,469,697 bp
  • A to T, chromosome 13 at 49,901,921 bp
  • G to A, chromosome 13 at 76,147,767 bp
  • A to G, chromosome 14 at 12,457,711 bp
  • A to T, chromosome 15 at 68,180,721 bp
  • A to G, chromosome 15 at 76,124,665 bp
  • C to A, chromosome 16 at 52,295,048 bp
  • T to C, chromosome 17 at 14,001,194 bp
  • A to G, chromosome 17 at 56,617,793 bp
  • A to C, chromosome 18 at 42,217,557 bp
  • G to A, chromosome 19 at 6,321,720 bp
  • T to A, chromosome 19 at 6,927,701 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5208 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042783-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.