Strain Name:
C57BL/6J-MtgxR5377Btlr/Mmmh
Stock Number:
042845-MU
Citation ID:
RRID:MMRRC_042845-MU
Other Names:
R5377 (G1), C57BL/6J-MtgxR5377Btlr
Major Collection:

Gene Information

B4galnt1
Name: beta-1,4-N-acetyl-galactosaminyl transferase 1
Synonyms: GalNAc-T, Ggm2, GM2/GD2 synthase, Ggm-2, beta1,4GalNAC-T, 4933429D13Rik, Galgt1, GalNAcT, Gal-NAc-T
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 14421
VEGA: 10
HGNC: HGNC:4117
Homologene: 1133
Nos2
Name: nitric oxide synthase 2, inducible
Synonyms: Nos2a, Nos-2, iNOS, NOS-II
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 18126
HGNC: HGNC:7873
Homologene: 55473
Adcy10
Name: adenylate cyclase 10
Synonyms: soluble adenylyl cyclase, sAC, 4930431D04Rik, Sacy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 271639
Homologene: 10188
Nucks1
Name: nuclear casein kinase and cyclin-dependent kinase substrate 1
Synonyms: 8430423A01Rik, 2700010L10Rik, Nucks
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 98415
Homologene: 23377
Trpm7
Name: transient receptor potential cation channel, subfamily M, member 7
Synonyms: LTRPC7, 5033407O22Rik, CHAK1, CHAK, 2310022G15Rik, Ltpr7, TRP-PLIK, 4833414K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 58800
Homologene: 9774
Asxl2
Name: additional sex combs like 2, transcriptional regulator
Synonyms: 4930556B16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 75302
Homologene: 10102
Zfhx3
Name: zinc finger homeobox 3
Synonyms: WBP9, Sci, A230102L03Rik, Atbf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 11906
HGNC: HGNC:777
Homologene: 21366
Lin9
Name: lin-9 homolog (C. elegans)
Synonyms: 2700022J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 72568
Homologene: 35252
Esrrb
Name: estrogen related receptor, beta
Synonyms: Err2, ERRb, ERR2, Estrrb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 26380
HGNC: HGNC:3473
Homologene: 69108
Ankrd11
Name: ankyrin repeat domain 11
Synonyms: 3010027A04Rik, Yod, 9530048I21Rik, 2410104C19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 77087
Homologene: 69134
Aspm
Name: abnormal spindle microtubule assembly
Synonyms: Sha1, D330028K02Rik, Calmbp1, Aspm, MCPH5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12316
Homologene: 7650
Trip12
Name: thyroid hormone receptor interactor 12
Synonyms: 6720416K24Rik, Gtl6, 1110036I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 14897
Homologene: 44226
Nav2
Name: neuron navigator 2
Synonyms: RAINB2, HELAD1, Unc53H2, 5330421F07Rik, POMFIL2, Rainb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 78286
Homologene: 52330
Akap8l
Name: A kinase (PRKA) anchor protein 8-like
Synonyms: Nakap95
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 54194
VEGA: 17
Homologene: 8658
Tmem245
Name: transmembrane protein 245
Synonyms: A630051L19Rik, D730040F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242474
HGNC: HGNC:1363
Homologene: 41841
Tacc1
Name: transforming, acidic coiled-coil containing protein 1
Synonyms: Tacc1, B230378H13Rik, 4833447E04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 320165
Homologene: 4575
Cftr
Name: cystic fibrosis transmembrane conductance regulator
Synonyms: Abcc7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 12638
HGNC: HGNC:1884
Homologene: 55465
Oga
Name: O-GlcNAcase
Synonyms: 2810009A20Rik, Hy5, 4833427O07Rik, 5830447M11Rik, Mgea5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 76055
VEGA: 19
HGNC: HGNC:7056
Homologene: 8154
Lepr
Name: leptin receptor
Synonyms: Leprb, LEPROT, Modb1, OB-RGRP, leptin receptor gene-related protein, obl, obese-like, Obr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 16847
HGNC: HGNC:6554
Homologene: 1731
Crebrf
Name: CREB3 regulatory factor
Synonyms: A930001N09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 77128
Homologene: 12672
Cecr2
Name: CECR2, histone acetyl-lysine reader
Synonyms: Gtl4, cat eye syndrome chromosome region, candidate 2, 2610101O16Rik, 2810409N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 330409
HGNC: HGNC:1840
Homologene: 64662
Eef1d
Name: eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
Synonyms: 5730529A16Rik, 1700026P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 66656
HGNC: HGNC:3211
Homologene: 23404
Lpin1
Name: lipin 1
Synonyms: Lipin1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 14245
VEGA: 12
Homologene: 9266
Npat
Name: nuclear protein in the AT region
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244879
HGNC: HGNC:7896
Homologene: 1888
Nus1
Name: NUS1 dehydrodolichyl diphosphate synthase subunit
Synonyms: NgBR, D10Ertd438e, 1600027K07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 52014
Homologene: 12719
Akr1a1
Name: aldo-keto reductase family 1, member A1 (aldehyde reductase)
Synonyms: Akr1a4, 2610201A18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 58810
HGNC: HGNC:380
Homologene: 74565
Rnf157
Name: ring finger protein 157
Synonyms: 2610036E23Rik, A130073L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217340
Homologene: 28235
Sec31b
Name: Sec31 homolog B (S. cerevisiae)
Synonyms: Sec31l2, LOC240667
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 240667
Homologene: 56708
Mlkl
Name: mixed lineage kinase domain-like
Synonyms: 9130019I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 74568
Homologene: 77416
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Acz, Pico
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 26875
Homologene: 69111
Dnah2
Name: dynein, axonemal, heavy chain 2
Synonyms: 2900022L05Rik, Dnahc2, D330014H01Rik, Dnhd3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 327954
HGNC: HGNC:2948
Homologene: 72110
Mttp
Name: microsomal triglyceride transfer protein
Synonyms: MTP, 1810043K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 17777
HGNC: HGNC:7467
Homologene: 212
Kctd18
Name: potassium channel tetramerisation domain containing 18
Synonyms: 4932411A20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 51960
Homologene: 12710
Fat3
Name: FAT atypical cadherin 3
Synonyms: LOC382129, 9430076A06Rik, LOC234973, D430038H04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 270120
VEGA: 9
Homologene: 82252
Ush2a
Name: usherin
Synonyms: Ush2a, Ushrn, MUSH2A, A930037M10Rik, A930011D15Rik, LOC269160, LOC381317
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 22283
Homologene: 66151
Hephl1
Name: hephaestin-like 1
Synonyms: LOC244698, cw, thd, Zp, zyklopen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244698
Homologene: 9112
Lama3
Name: laminin, alpha 3
Synonyms: nicein, 150kDa, [a]3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 16774
HGNC: HGNC:6483
Homologene: 18279
Cfap44
Name: cilia and flagella associated protein 44
Synonyms: 6330444M21Rik, D16Ertd642e, Wdr52
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 212517
Homologene: 75085
Cyp4f40
Name: cytochrome P450, family 4, subfamily f, polypeptide 40
Synonyms: EG631304
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 631304
VEGA: 17
Homologene: 117991
A2m
Name: alpha-2-macroglobulin
Synonyms: A2mp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232345
HGNC: HGNC:7
Homologene: 37248
Rpgrip1
Name: retinitis pigmentosa GTPase regulator interacting protein 1
Synonyms: 4930505G06Rik, nmf247, A930002K18Rik, 4930401L23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 77945
Homologene: 10679
Irs2
Name: insulin receptor substrate 2
Synonyms: Irs-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 384783
HGNC: HGNC:6126
Homologene: 2778
Pign
Name: phosphatidylinositol glycan anchor biosynthesis, class N
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 27392
HGNC: HGNC:8967
Homologene: 6330
Slc22a30
Name: solute carrier family 22, member 30
Synonyms: C730048C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 319800
Homologene: 77136
Rufy4
Name: RUN and FYVE domain containing 4
Synonyms: F930048N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 435626
Homologene: 52359
Vmn2r66
Name: vomeronasal 2, receptor 66
Synonyms: F830104D24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233437
Homologene: 115466
Rfx4
Name: regulatory factor X, 4 (influences HLA class II expression)
Synonyms: 4933412G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 71137
HGNC: HGNC:9985
Homologene: 31119
Lrit2
Name: leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
Synonyms: A930010E21Rik, Lrrc22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 239038
VEGA: 14
Homologene: 18292
Atp6v0a1
Name: ATPase, H+ transporting, lysosomal V0 subunit A1
Synonyms: V-ATPase a1, Vpp1, Atp6n1a, Atp6n1, Vpp-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 11975
HGNC: HGNC:865
Homologene: 3795
Alk
Name: anaplastic lymphoma kinase
Synonyms: CD246, Tcrz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 11682
VEGA: 17
HGNC: HGNC:427
Homologene: 68387
Wdhd1
Name: WD repeat and HMG-box DNA binding protein 1
Synonyms: D630024B06Rik, AND-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 218973
Homologene: 56019
Scaf11
Name: SR-related CTD-associated factor 11
Synonyms: SRRP129, 2610510E10Rik, SIP1, 1110061H03Rik, CASP11, Sfrs2ip, Srsf2ip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 72193
VEGA: 15
Homologene: 37957
Vmn2r99
Name: vomeronasal 2, receptor 99
Synonyms: EG665376
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 665376
Homologene: 115024
Defb12
Name: defensin beta 12
Synonyms: 9230103N16Rik, mBD-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 77674
Homologene: 17531
Exd2
Name: exonuclease 3'-5' domain containing 2
Synonyms: Exdl2, 4930539P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 97827
VEGA: 12
Homologene: 10066
Olfr881
Name: olfactory receptor 881
Synonyms: MOR162-7, GA_x6K02T2PVTD-31676771-31677700
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258413
Homologene: 74013
Zfp82
Name: zinc finger protein 82
Synonyms: KRAB16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 330502
Homologene: 51177
Olfr1230
Name: olfactory receptor 1230
Synonyms: GA_x6K02T2Q125-50741934-50741017, MOR237-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258785
Homologene: 81570
Dpysl5
Name: dihydropyrimidinase-like 5
Synonyms: CRAM, CRMP-5, Crmp5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 65254
Homologene: 41347
Zfp446
Name: zinc finger protein 446
Synonyms: A630035I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 269870
Homologene: 9910
Slc17a2
Name: solute carrier family 17 (sodium phosphate), member 2
Synonyms: NPT3, C730032N17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218103
Homologene: 4260
Adgrg7
Name: adhesion G protein-coupled receptor G7
Synonyms: 9130020O16Rik, Gpr128
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 239853
Homologene: 13115
Ccdc114
Name: coiled-coil domain containing 114
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 211535
Homologene: 128610
Vmn1r192
Name: vomeronasal 1 receptor 192
Synonyms: V1ri1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 252907
Homologene: 110880
Slc16a9
Name: solute carrier family 16 (monocarboxylic acid transporters), member 9
Synonyms: 4930425B13Rik, 1200003C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 66859
Homologene: 32642
Gm5454
Name: predicted gene 5454
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 432800
VEGA: 13
AC161246.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 57,963,093 bp
  • T to C, chromosome 1 at 74,147,663 bp
  • T to C, chromosome 1 at 84,757,431 bp
  • A to T, chromosome 1 at 105,657,812 bp
  • T to C, chromosome 1 at 131,919,033 bp
  • T to A, chromosome 1 at 139,457,483 bp
  • A to G, chromosome 1 at 139,470,395 bp
  • G to A, chromosome 1 at 165,519,895 bp
  • A to C, chromosome 1 at 180,674,151 bp
  • G to A, chromosome 1 at 188,912,123 bp
  • G to T, chromosome 2 at 89,297,162 bp
  • C to A, chromosome 2 at 126,842,855 bp
  • C to T, chromosome 3 at 138,105,029 bp
  • G to A, chromosome 4 at 56,947,084 bp
  • T to C, chromosome 4 at 101,815,019 bp
  • A to T, chromosome 4 at 116,639,895 bp
  • A to G, chromosome 5 at 14,681,353 bp
  • A to T, chromosome 5 at 30,791,513 bp
  • T to C, chromosome 6 at 18,268,017 bp
  • A to G, chromosome 6 at 120,756,569 bp
  • G to T, chromosome 6 at 121,645,253 bp
  • T to C, chromosome 7 at 12,982,251 bp
  • T to C, chromosome 7 at 30,057,166 bp
  • C to T, chromosome 7 at 45,942,082 bp
  • T to C, chromosome 7 at 49,589,160 bp
  • A to T, chromosome 7 at 85,006,818 bp
  • A to G, chromosome 8 at 11,005,277 bp
  • C to A, chromosome 8 at 19,114,326 bp
  • A to G, chromosome 8 at 25,182,283 bp
  • C to T, chromosome 8 at 108,951,185 bp
  • T to A, chromosome 8 at 111,327,937 bp
  • T to C, chromosome 8 at 122,893,714 bp
  • T to C, chromosome 9 at 15,069,788 bp
  • T to A, chromosome 9 at 16,376,443 bp
  • A to T, chromosome 9 at 37,992,612 bp
  • A to G, chromosome 9 at 53,550,036 bp
  • T to C, chromosome 9 at 110,040,217 bp
  • T to C, chromosome 10 at 52,429,213 bp
  • T to A, chromosome 10 at 70,283,128 bp
  • A to G, chromosome 10 at 84,860,542 bp
  • A to G, chromosome 10 at 127,171,822 bp
  • T to C, chromosome 11 at 69,421,848 bp
  • A to T, chromosome 11 at 78,957,491 bp
  • A to G, chromosome 11 at 101,055,587 bp
  • G to A, chromosome 11 at 116,347,066 bp
  • G to A, chromosome 12 at 3,474,618 bp
  • C to T, chromosome 12 at 16,563,655 bp
  • T to C, chromosome 12 at 80,489,448 bp
  • C to T, chromosome 12 at 86,519,009 bp
  • C to T, chromosome 13 at 22,187,631 bp
  • T to C, chromosome 13 at 23,812,592 bp
  • C to A, chromosome 13 at 103,356,549 bp
  • A to C, chromosome 14 at 37,069,183 bp
  • A to C, chromosome 14 at 47,272,221 bp
  • A to T, chromosome 14 at 52,160,195 bp
  • G to T, chromosome 15 at 75,903,189 bp
  • T to A, chromosome 15 at 96,417,120 bp
  • T to C, chromosome 16 at 44,421,262 bp
  • A to C, chromosome 16 at 56,730,306 bp
  • T to C, chromosome 17 at 19,379,269 bp
  • T to C, chromosome 17 at 26,759,865 bp
  • T to C, chromosome 17 at 32,321,511 bp
  • A to T, chromosome 17 at 32,675,616 bp
  • T to G, chromosome 17 at 71,895,739 bp
  • A to G, chromosome 18 at 12,453,746 bp
  • G to A, chromosome 19 at 8,344,393 bp
  • G to T, chromosome 19 at 44,518,637 bp
  • A to T, chromosome 19 at 45,758,022 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5377 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042845-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.