Strain Name:
C57BL/6J-MtgxR5285Btlr/Mmmh
Stock Number:
042869-MU
Citation ID:
RRID:MMRRC_042869-MU
Other Names:
R5285 (G1), C57BL/6J-MtgxR5285Btlr
Major Collection:

Gene Information

Ncor1
Name: nuclear receptor co-repressor 1
Synonyms: N-CoR, Rxrip13, A230020K14Rik, 5730405M06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20185
HGNC: HGNC:7672
Homologene: 38166
Sh3gl2
Name: SH3-domain GRB2-like 2
Synonyms: EEN-B1, endophilin I, Sh3d2a, 9530001L19Rik, B930049H17Rik, endophilin A1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 20404
Homologene: 20652
Aldh1l1
Name: aldehyde dehydrogenase 1 family, member L1
Synonyms: 1810048F20Rik, Fthfd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 107747
HGNC: HGNC:3978
Homologene: 122031
Lyst
Name: lysosomal trafficking regulator
Synonyms: D13Sfk13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17101
VEGA: 13
HGNC: HGNC:1968
Homologene: 61
Crhr1
Name: corticotropin releasing hormone receptor 1
Synonyms: CRFR1, CRF-R1alpha, CRF 1 receptor, CRF1R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12921
HGNC: HGNC:2357
Homologene: 20920
Zfp7
Name: zinc finger protein 7
Synonyms: Krox-2, Zfp-7, Zfp65, mszf73-2, KRAB7, Zfp80, KRAB20, Zfp86-rs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223669
VEGA: 15
Homologene: 20729
Prmt7
Name: protein arginine N-methyltransferase 7
Synonyms: 4933402B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 214572
Homologene: 10382
Sorbs1
Name: sorbin and SH3 domain containing 1
Synonyms: c-Cbl-associated protein, CAP, Sh3d5, 9530001P15Rik, 2310065E01Rik, Ponsin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 20411
VEGA: 19
Homologene: 83252
Nav2
Name: neuron navigator 2
Synonyms: POMFIL2, Unc53H2, HELAD1, RAINB2, 5330421F07Rik, Rainb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 78286
Homologene: 52330
Usp24
Name: ubiquitin specific peptidase 24
Synonyms: 2810030C21Rik, 2700066K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329908
Homologene: 35420
Chek1
Name: checkpoint kinase 1
Synonyms: Chk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12649
HGNC: HGNC:1925
Homologene: 975
Acbd6
Name: acyl-Coenzyme A binding domain containing 6
Synonyms: 0610010G04Rik, 2610100E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 72482
Homologene: 12465
Polg
Name: polymerase (DNA directed), gamma
Synonyms: Pol gamma, polymerase gamma, mitochondrial DNA polymerase gamma, mitochondrial DNA polymerase-gamma, Polga
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18975
HGNC: HGNC:9179
Homologene: 2016
Lrrn2
Name: leucine rich repeat protein 2, neuronal
Synonyms: NLRR-2, 5730406J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16980
Homologene: 21274
Rhpn2
Name: rhophilin, Rho GTPase binding protein 2
Synonyms: 1300002E07Rik, D7Ertd784e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 52428
Homologene: 12407
Zfp940
Name: zinc finger protein 940
Synonyms: BC027344
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233057
Homologene: 138421
Gm6445
Name: predicted gene 6445
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 623688
Robo4
Name: roundabout guidance receptor 4
Synonyms: 1200012D01Rik, Magic roundabout
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74144
Homologene: 10397
Atl1
Name: atlastin GTPase 1
Synonyms: AD-FSP, SPG3, FSP1, Spg3a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 73991
VEGA: 12
Homologene: 9302
Cep295
Name: centrosomal protein 295
Synonyms: LOC382128, 5830418K08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 319675
Homologene: 27936
Avil
Name: advillin
Synonyms: DOC6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 11567
Homologene: 38200
Steap3
Name: STEAP family member 3
Synonyms: pHyde, 1010001D01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68428
Homologene: 10084
Pla2g4e
Name: phospholipase A2, group IVE
Synonyms: 2310026J01Rik, Pla2epsilon
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329502
Homologene: 65339
Msh4
Name: mutS homolog 4
Synonyms: mMsh4, 4930485C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 55993
HGNC: HGNC:7327
Homologene: 1830
Dcdc5
Name: doublecortin domain containing 5
Synonyms: 4732421G10Rik, EG436559
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329482
Homologene: 79722
Gucy2d
Name: guanylate cyclase 2d
Synonyms: guanylyl cyclase D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 14918
Homologene: 71540
Stxbp5
Name: syntaxin binding protein 5 (tomosyn)
Synonyms: 0710001E20Rik, LGL3, 4930565N16Rik, tomosyn 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 78808
Homologene: 16402
Sarm1
Name: sterile alpha and HEAT/Armadillo motif containing 1
Synonyms: MyD88-5, A830091I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237868
Homologene: 9015
Adcy8
Name: adenylate cyclase 8
Synonyms: AC8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 11514
VEGA: 15
HGNC: HGNC:239
Homologene: 37443
Inhbc
Name: inhibin beta-C
Synonyms: activin beta-C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16325
VEGA: 10
HGNC: HGNC:6068
Homologene: 21142
Sycp2
Name: synaptonemal complex protein 2
Synonyms: 3830402K23Rik, 4930518F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 320558
Homologene: 8604
Stab1
Name: stabilin 1
Synonyms: MS-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 192187
Homologene: 9035
Olfr195
Name: olfactory receptor 195
Synonyms: GA_x54KRFPKG5P-55369823-55370749, MOR184-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 259000
Homologene: 128109
Tm6sf1
Name: transmembrane 6 superfamily member 1
Synonyms: C630016D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 107769
Homologene: 11305
Gm16432
Name: predicted gene 16432
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
4933405L10Rik
Name: RIKEN cDNA 4933405L10 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 71046
Homologene: 19274
Mug1
Name: murinoglobulin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 17836
Homologene: 136663
Mroh5
Name: maestro heat-like repeat family member 5
Synonyms: LOC268816, Gm628
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 268816
Plxnb1
Name: plexin B1
Synonyms: 2900002G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235611
HGNC: HGNC:9103
Homologene: 130508
Ergic3
Name: ERGIC and golgi 3
Synonyms: CGI-54, NY-BR-84, 2310015B14Rik, D2Ucla1, Sdbcag84
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66366
Homologene: 5289
Olfr593
Name: olfactory receptor 593
Synonyms: GA_x6K02T2PBJ9-5927412-5928362, MOR24-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258378
Homologene: 27147
Ap1m2
Name: adaptor protein complex AP-1, mu 2 subunit
Synonyms: [m]1B, mu1B, D9Ertd818e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 11768
VEGA: 9
HGNC: HGNC:558
Homologene: 55906
Vmn2r120
Name: vomeronasal 2, receptor 120
Synonyms: EG224916
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224916
Cfh
Name: complement component factor h
Synonyms: Sas-1, Mud-1, Sas1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12628
HGNC: HGNC:4883
Homologene: 20086
Sgip1
Name: SH3-domain GRB2-like (endophilin) interacting protein 1
Synonyms: 3110007P09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 73094
Homologene: 13001
Vmn2r14
Name: vomeronasal 2, receptor 14
Synonyms: EG231591
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231591
Homologene: 129606
Cyp3a11
Name: cytochrome P450, family 3, subfamily a, polypeptide 11
Synonyms: IIIAm1, Cyp3a, Pcn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13112
HGNC: HGNC:2638
Homologene: 133568
Cpox
Name: coproporphyrinogen oxidase
Synonyms: clone 560, cac, Cpo, nct
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 12892
VEGA: 16
HGNC: HGNC:2321
Homologene: 76
Vmn1r200
Name: vomeronasal 1 receptor 200
Synonyms: V1rh3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 171246
Homologene: 110880
Cd177
Name: CD177 antigen
Synonyms: Pdp3, 1190003K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 68891
Homologene: 49628
Fabp3-ps1
Name: fatty acid binding protein 3, muscle and heart, pseudogene 1
Synonyms: Fabph-3, Fabph3, Fabph-ps1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14074
VEGA: 10
Prl8a2
Name: prolactin family 8, subfamily a, member 2
Synonyms: D/tPRP, DPRP, mdPRP, Dtprp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 13529
Homologene: 49230
Olfr384
Name: olfactory receptor 384
Synonyms: GA_x6K02T2P1NL-3773152-3774090, GA_x6K02T2P1NL-3739520-3740032, MOR135-5, Olfr386
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 193053
Homologene: 105206
Caps2
Name: calcyphosphine 2
Synonyms: D630005B03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 353025
Homologene: 72278
Apobr
Name: apolipoprotein B receptor
Synonyms: Apob-48r, Apob48r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 171504
Homologene: 26695
Rad18
Name: RAD18 E3 ubiquitin protein ligase
Synonyms: 2810024C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 58186
Homologene: 48572
Spns2
Name: spinster homolog 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216892
Homologene: 71040
Vwa1
Name: von Willebrand factor A domain containing 1
Synonyms: WARP, 4932416A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 246228
Homologene: 11270
Psg17
Name: pregnancy specific glycoprotein 17
Synonyms: mmCGM5, Cea-2, Cea2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 26437
Homologene: 110989
Olfr645
Name: olfactory receptor 645
Synonyms: GA_x6K02T2PBJ9-6819097-6818150, MOR13-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258247
Homologene: 66155
Nipa2
Name: non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)
Synonyms: 2600017P10Rik, 3830408P04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 93790
Homologene: 11368
Olfr178
Name: olfactory receptor 178
Synonyms: GA_x54KRFPKG5P-55108059-55107100, MOR184-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 258999
Homologene: 79412
Igkv2-116
Name: immunoglobulin kappa variable 2-116
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 434026
Ighv1-19-1
Name: immunoglobulin heavy variable 1-19-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 668493
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 120,241,880 bp
  • T to A, chromosome 1 at 132,939,245 bp
  • T to C, chromosome 1 at 140,100,898 bp
  • T to A, chromosome 1 at 155,558,725 bp
  • A to G, chromosome 1 at 178,103,888 bp
  • A to T, chromosome 2 at 106,368,155 bp
  • T to C, chromosome 2 at 120,189,504 bp
  • A to G, chromosome 2 at 156,018,037 bp
  • A to T, chromosome 2 at 178,392,398 bp
  • T to C, chromosome 3 at 153,873,713 bp
  • A to G, chromosome 4 at 85,376,449 bp
  • T to A, chromosome 4 at 102,921,477 bp
  • T to A, chromosome 4 at 106,407,033 bp
  • C to T, chromosome 4 at 155,770,895 bp
  • T to C, chromosome 5 at 109,217,576 bp
  • A to G, chromosome 5 at 145,855,083 bp
  • G to T, chromosome 6 at 68,152,479 bp
  • A to T, chromosome 6 at 90,576,770 bp
  • T to C, chromosome 6 at 112,686,765 bp
  • G to A, chromosome 6 at 121,841,107 bp
  • T to A, chromosome 7 at 18,820,201 bp
  • A to T, chromosome 7 at 24,746,249 bp
  • A to T, chromosome 7 at 29,845,600 bp
  • G to T, chromosome 7 at 35,381,565 bp
  • T to C, chromosome 7 at 49,548,234 bp
  • A to T, chromosome 7 at 55,933,012 bp
  • A to G, chromosome 7 at 79,465,225 bp
  • A to G, chromosome 7 at 81,859,452 bp
  • C to A, chromosome 7 at 98,458,267 bp
  • C to T, chromosome 7 at 103,212,798 bp
  • A to G, chromosome 7 at 104,084,133 bp
  • A to G, chromosome 7 at 126,585,003 bp
  • A to G, chromosome 8 at 105,708,465 bp
  • G to A, chromosome 8 at 106,248,359 bp
  • T to C, chromosome 9 at 15,322,591 bp
  • G to T, chromosome 9 at 21,305,637 bp
  • T to C, chromosome 9 at 36,714,452 bp
  • CGG to CG, chromosome 9 at 37,411,490 bp
  • C to T, chromosome 9 at 109,108,459 bp
  • T to C, chromosome 10 at 9,798,275 bp
  • T to G, chromosome 10 at 86,732,202 bp
  • T to A, chromosome 10 at 112,208,311 bp
  • T to C, chromosome 10 at 127,018,459 bp
  • C to A, chromosome 10 at 127,357,400 bp
  • A to G, chromosome 11 at 62,392,649 bp
  • G to A, chromosome 11 at 72,489,479 bp
  • T to A, chromosome 11 at 73,602,941 bp
  • A to G, chromosome 11 at 78,497,439 bp
  • A to T, chromosome 11 at 104,170,497 bp
  • A to G, chromosome 12 at 69,954,499 bp
  • C to A, chromosome 12 at 114,704,252 bp
  • T to C, chromosome 13 at 13,634,426 bp
  • G to A, chromosome 13 at 22,395,287 bp
  • G to A, chromosome 13 at 27,350,133 bp
  • A to G, chromosome 14 at 31,143,476 bp
  • G to T, chromosome 15 at 64,767,857 bp
  • TGGAG to TG, chromosome 15 at 73,783,074 bp
  • G to A, chromosome 15 at 76,891,222 bp
  • G to A, chromosome 16 at 58,675,286 bp
  • A to T, chromosome 16 at 58,890,108 bp
  • T to C, chromosome 16 at 59,149,270 bp
  • A to G, chromosome 17 at 57,536,703 bp
  • C to A, chromosome 19 at 9,607,668 bp
  • G to A, chromosome 19 at 40,321,890 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5285 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042869-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.