Strain Name:
C57BL/6J-MtgxR5303Btlr/Mmmh
Stock Number:
042886-MU
Citation ID:
RRID:MMRRC_042886-MU
Other Names:
R5303 (G1), C57BL/6J-MtgxR5303Btlr
Major Collection:

Gene Information

Ppp5c
Name: protein phosphatase 5, catalytic subunit
Synonyms: PP5, ANP receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 19060
HGNC: HGNC:9322
Homologene: 4550
Ank2
Name: ankyrin 2, brain
Synonyms: Ank-2, ankyrin B, Gm4392, Ankyrin-B, Ankyrin-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 109676
HGNC: HGNC:493
Wdfy3
Name: WD repeat and FYVE domain containing 3
Synonyms: Bchs, D5Ertd66e, Alfy, 2610509D04Rik, Ggtb3, Bwf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 72145
Homologene: 22855
Eif4g3
Name: eukaryotic translation initiation factor 4 gamma, 3
Synonyms: eIF4GII, 1500002J22Rik, G1-419-52, repro8, 4930523M17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230861
HGNC: HGNC:3298
Homologene: 2789
Zfat
Name: zinc finger and AT hook domain containing
Synonyms: Zfat1, Zfp406, LOC380993
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 380993
Homologene: 16829
Arid2
Name: AT rich interactive domain 2 (ARID, RFX-like)
Synonyms: 4432409D24Rik, zipzap/p200, 1700124K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 77044
Homologene: 14601
Mical3
Name: microtubule associated monooxygenase, calponin and LIM domain containing 3
Synonyms: C130040D16Rik, MICAL-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 194401
Homologene: 85288
Epb41l3
Name: erythrocyte membrane protein band 4.1 like 3
Synonyms: DAL1P, Epb4.1l3, 4.1B, NBL3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13823
HGNC: HGNC:3380
Homologene: 49308
Ube4b
Name: ubiquitination factor E4B
Synonyms: D4Bwg0973e, 4933406G05Rik, UFD2, Ufd2p, UFD2a, 4930551I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 63958
Homologene: 107623
Tbc1d5
Name: TBC1 domain family, member 5
Synonyms: 1600014N05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 72238
VEGA: 17
Homologene: 8834
Zfyve1
Name: zinc finger, FYVE domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217695
VEGA: 12
Homologene: 10945
Map3k20
Name: mitogen-activated protein kinase kinase kinase 20
Synonyms: MLTKalpha, Zak, MLTKbeta, B230120H23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 65964
Homologene: 32331
Syne1
Name: spectrin repeat containing, nuclear envelope 1
Synonyms: enaptin165, C130039F11Rik, A330049M09Rik, nesprin-1, SYNE-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 64009
VEGA: 10
Homologene: 52329
Cinp
Name: cyclin-dependent kinase 2 interacting protein
Synonyms: 2810452K22Rik, 1810047K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 67236
VEGA: 12
Homologene: 12103
Abr
Name: active BCR-related gene
Synonyms: 6330400K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 109934
HGNC: HGNC:81
Homologene: 11081
Notch1
Name: notch 1
Synonyms: Mis6, Tan1, N1, lin-12, 9930111A19Rik, Motch A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18128
HGNC: HGNC:7881
Homologene: 32049
Eapp
Name: E2F-associated phosphoprotein
Synonyms: 1810011O16Rik, EAPP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 66266
Homologene: 10206
Sugp2
Name: SURP and G patch domain containing 2
Synonyms: Srsf14, Sfrs14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234373
Homologene: 8923
1600029O15Rik
Name: RIKEN cDNA 1600029O15 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 665268
Itpr3
Name: inositol 1,4,5-triphosphate receptor 3
Synonyms: Itpr-3, tf, Ip3r3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16440
HGNC: HGNC:6182
Homologene: 1675
Ryr1
Name: ryanodine receptor 1, skeletal muscle
Synonyms: calcium release channel isoform 1, skrr, Ryr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20190
Homologene: 68069
Foxp2
Name: forkhead box P2
Synonyms: D0Kist7, 2810043D05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 114142
Homologene: 134404
Spdye4b
Name: speedy/RINGO cell cycle regulator family, member E4B
Synonyms: 4933411G11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 330228
Homologene: 138445
Mylk3
Name: myosin light chain kinase 3
Synonyms: D830007F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 213435
Homologene: 35278
C3ar1
Name: complement component 3a receptor 1
Synonyms: anaphylatoxin C3a receptor, C3aR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12267
HGNC: HGNC:1319
Homologene: 2992
Cplane1
Name: ciliogenesis and planar polarity effector 1
Synonyms: Jbts17, b2b012Clo, 2410089E03Rik, Hug
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 73692
Homologene: 11315
Col6a3
Name: collagen, type VI, alpha 3
Synonyms: Col6a-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12835
HGNC: HGNC:2213
Homologene: 37917
Abcc12
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 12
Synonyms: MRP9, 4930467B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244562
Homologene: 57211
Acss3
Name: acyl-CoA synthetase short-chain family member 3
Synonyms: LOC380660, 8430416H19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 380660
Homologene: 11587
Rhbdl2
Name: rhomboid like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230726
Homologene: 49508
Myh1
Name: myosin, heavy polypeptide 1, skeletal muscle, adult
Synonyms: IId, IId/x, Myhs-f2, Myhs-f, A530084A17Rik, MyHC-IId/x, MYHC-IIX, myosin heavy chain 2X, Myhsf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17879
HGNC: HGNC:7567
Homologene: 133718
Olfr1245
Name: olfactory receptor 1245
Synonyms: MOR231-12, GA_x6K02T2Q125-51020951-51020028
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258784
Homologene: 121560
Hal
Name: histidine ammonia lyase
Synonyms: Hsd, histidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 15109
HGNC: HGNC:4806
Homologene: 68229
Nlrc3
Name: NLR family, CARD domain containing 3
Synonyms: Caterpiller 16.2, CLR16.2, D230007K08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 268857
Homologene: 18720
Gria1
Name: glutamate receptor, ionotropic, AMPA1 (alpha 1)
Synonyms: Glur-1, GluA1, GluR-A, Glr1, GluR1, HIPA1, GluRA, Glr-1, 2900051M01Rik, Glur1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14799
HGNC: HGNC:4571
Homologene: 20226
Zyg11a
Name: zyg-11 family member A, cell cycle regulator
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230590
Homologene: 66294
1700006A11Rik
Name: RIKEN cDNA 1700006A11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 71824
Disp2
Name: dispatched RND tramsporter family member 2
Synonyms: DispB, B230210L08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 214240
Homologene: 24916
Chrna1
Name: cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
Synonyms: Acra, Achr-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11435
HGNC: HGNC:1955
Homologene: 59
Postn
Name: periostin, osteoblast specific factor
Synonyms: peri, Osf2, OSF-2, A630052E07Rik, Periostin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 50706
Homologene: 4730
Tmem260
Name: transmembrane protein 260
Synonyms: 6720456H20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 218989
Homologene: 49506
Vmn1r235
Name: vomeronasal 1 receptor 235
Synonyms: V1rf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 171233
Homologene: 74360
B3glct
Name: beta-3-glucosyltransferase
Synonyms: B3galtl, LOC381694
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381694
Homologene: 14978
Adra1d
Name: adrenergic receptor, alpha 1d
Synonyms: Gpcr8, Adra1a, Adra1, Adra-1, alpha1D-AR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11550
HGNC: HGNC:280
Homologene: 551
Cd46
Name: CD46 antigen, complement regulatory protein
Synonyms: Mcp, CD46
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 17221
HGNC: HGNC:6953
Homologene: 7832
Hdac7
Name: histone deacetylase 7
Synonyms: 5830434K02Rik, Hdac7a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 56233
Homologene: 9124
Cd1d1
Name: CD1d1 antigen
Synonyms: Cd1d, CD1.1, Ly-38, Cd1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12479
HGNC: HGNC:1637
Homologene: 1337
Niban3
Name: niban apoptosis regulator 3
Synonyms: Fam129c, Bcnp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 100037278
Homologene: 45462
4921504E06Rik
Name: RIKEN cDNA 4921504E06 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 70909
Homologene: 87049
Gm11595
Name: predicted gene 11595
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 100040276
Homologene: 124486
Olfr1454
Name: olfactory receptor 1454
Synonyms: MOR202-14, GA_x6K02T2RE5P-3390804-3391727
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258687
Homologene: 120159
4930516K23Rik
Name: RIKEN cDNA 4930516K23 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Septin14
Name: septin 14
Synonyms: 1700016K13Rik, Sept14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74222
Homologene: 87501
Zfp850
Name: zinc finger protein 850
Synonyms: Gm4636, C130069I09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100043772
Fermt1
Name: fermitin family member 1
Synonyms: 5830467P10Rik, Kindlin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241639
Homologene: 9773
Zfp758
Name: zinc finger protein 758
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224598
Homologene: 138293
Slc38a8
Name: solute carrier family 38, member 8
Synonyms: LOC234788
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234788
Homologene: 19028
Dnaaf6
Name: dynein axonemal assembly factor 6
Synonyms: Pih1d3, 4930521A18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74708
Homologene: 16553
Olfr979
Name: olfactory receptor 979
Synonyms: GA_x6K02T2PVTD-33699706-33698771, MOR223-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 259112
VEGA: 9
Homologene: 81556
Qsox1
Name: quiescin Q6 sulfhydryl oxidase 1
Synonyms: b2b2673Clo, 1300003H02Rik, QSOX, Qscn6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 104009
HGNC: HGNC:9756
Homologene: 37690
Saysd1
Name: SAYSVFN motif domain containing 1
Synonyms: 4930488P03Rik, 1810063B07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 67509
VEGA: 14
Homologene: 41248
Tmed1
Name: transmembrane p24 trafficking protein 1
Synonyms: Ly84l, Il1rl1l, St2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17083
VEGA: 9
Homologene: 21360
Sh3bp5
Name: SH3-domain binding protein 5 (BTK-associated)
Synonyms: Sab
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 24056
Homologene: 23450
Ttc6
Name: tetratricopeptide repeat domain 6
Synonyms: 4921506M07Rik, AU024163, EG639426, Gm9813, LOC217602
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 70846
Homologene: 78002
Gm27516
Name: predicted gene, 27516
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 31,223,456 bp
  • G to C, chromosome 1 at 90,801,531 bp
  • T to C, chromosome 1 at 155,779,293 bp
  • T to C, chromosome 1 at 195,062,399 bp
  • A to G, chromosome 2 at 19,516,299 bp
  • C to T, chromosome 2 at 26,478,619 bp
  • C to T, chromosome 2 at 72,355,626 bp
  • T to C, chromosome 2 at 73,566,274 bp
  • T to A, chromosome 2 at 89,575,001 bp
  • T to C, chromosome 2 at 118,810,848 bp
  • G to A, chromosome 2 at 131,546,249 bp
  • T to C, chromosome 2 at 132,911,339 bp
  • A to G, chromosome 3 at 54,377,597 bp
  • A to G, chromosome 3 at 86,998,120 bp
  • C to G, chromosome 3 at 124,406,350 bp
  • A to T, chromosome 3 at 126,945,804 bp
  • C to T, chromosome 4 at 108,184,432 bp
  • A to G, chromosome 4 at 123,810,221 bp
  • T to C, chromosome 4 at 138,126,562 bp
  • T to C, chromosome 4 at 149,383,803 bp
  • T to C, chromosome 5 at 101,952,983 bp
  • T to A, chromosome 5 at 129,689,648 bp
  • C to T, chromosome 5 at 143,202,403 bp
  • C to T, chromosome 5 at 149,754,023 bp
  • T to A, chromosome 6 at 15,324,637 bp
  • G to T, chromosome 6 at 120,959,980 bp
  • A to T, chromosome 6 at 122,849,835 bp
  • G to T, chromosome 7 at 17,005,284 bp
  • C to T, chromosome 7 at 28,008,413 bp
  • C to T, chromosome 7 at 29,068,482 bp
  • T to C, chromosome 7 at 104,069,032 bp
  • T to A, chromosome 8 at 70,242,177 bp
  • C to T, chromosome 8 at 71,607,648 bp
  • T to A, chromosome 8 at 85,350,476 bp
  • C to A, chromosome 8 at 86,509,786 bp
  • C to A, chromosome 8 at 119,486,041 bp
  • G to T, chromosome 9 at 21,510,047 bp
  • A to G, chromosome 9 at 40,000,588 bp
  • A to T, chromosome 9 at 58,208,275 bp
  • T to C, chromosome 10 at 5,420,464 bp
  • A to G, chromosome 10 at 93,516,365 bp
  • T to A, chromosome 10 at 107,084,851 bp
  • A to G, chromosome 11 at 57,243,025 bp
  • T to C, chromosome 11 at 67,202,017 bp
  • A to G, chromosome 11 at 76,472,567 bp
  • G to A, chromosome 11 at 99,772,555 bp
  • G to A, chromosome 12 at 54,692,918 bp
  • T to A, chromosome 12 at 57,575,820 bp
  • A to T, chromosome 12 at 83,575,056 bp
  • G to A, chromosome 12 at 110,876,861 bp
  • T to A, chromosome 13 at 31,626,480 bp
  • T to C, chromosome 14 at 20,082,958 bp
  • C to A, chromosome 14 at 31,377,495 bp
  • T to C, chromosome 14 at 48,507,176 bp
  • G to A, chromosome 15 at 8,260,690 bp
  • A to T, chromosome 15 at 68,110,486 bp
  • G to A, chromosome 15 at 96,392,468 bp
  • C to A, chromosome 15 at 97,798,018 bp
  • A to T, chromosome 16 at 3,963,614 bp
  • C to A, chromosome 17 at 21,262,006 bp
  • A to G, chromosome 17 at 22,374,861 bp
  • T to C, chromosome 17 at 27,116,689 bp
  • A to T, chromosome 17 at 50,736,200 bp
  • G to C, chromosome 17 at 69,257,449 bp
  • T to A, chromosome 19 at 13,063,775 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5303 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042886-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.