Strain Name:
C57BL/6J-MtgxR5323Btlr/Mmmh
Stock Number:
042906-MU
Citation ID:
RRID:MMRRC_042906-MU
Other Names:
R5323 (G1), C57BL/6J-MtgxR5323Btlr
Major Collection:

Gene Information

Shprh
Name: SNF2 histone linker PHD RING helicase
Synonyms: 2610103K11Rik, D230017O13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 268281
Homologene: 6489
Fn1
Name: fibronectin 1
Synonyms: Fn-1, Fn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14268
HGNC: HGNC:3778
Homologene: 1533
Tert
Name: telomerase reverse transcriptase
Synonyms: TR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 21752
VEGA: 13
Homologene: 31141
Zfp638
Name: zinc finger protein 638
Synonyms: Np220, Zfml
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 18139
Homologene: 7447
Polr3a
Name: polymerase (RNA) III (DNA directed) polypeptide A
Synonyms: RPC155, RPC1, 9330175N20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 218832
VEGA: 14
Homologene: 5124
Tex9
Name: testis expressed gene 9
Synonyms: tsec-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 21778
Homologene: 32072
Gabpa
Name: GA repeat binding protein, alpha
Synonyms: GABPalpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 14390
HGNC: HGNC:4071
Homologene: 1543
Atxn10
Name: ataxin 10
Synonyms: TEG-169, E46, Sca10, Tex169
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 54138
VEGA: 15
Homologene: 40858
Camsap1
Name: calmodulin regulated spectrin-associated protein 1
Synonyms: PRO2405, 9530003A05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227634
Homologene: 19202
Zfp318
Name: zinc finger protein 318
Synonyms: TZF, 2610034E08Rik, D530032D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 57908
Homologene: 22808
Zic2
Name: zinc finger protein of the cerebellum 2
Synonyms: GENA 29, Ku, odd-paired homolog
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 22772
Homologene: 5171
Capns1
Name: calpain, small subunit 1
Synonyms: Capa-4, Capa4, D7Ertd146e, Capn4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12336
HGNC: HGNC:1481
Homologene: 1327
Pirb
Name: paired Ig-like receptor B
Synonyms: Gp91, Lilrb3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18733
Homologene: 134028
Pum2
Name: pumilio RNA-binding family member 2
Synonyms: Pumm2, 5730503J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 80913
Homologene: 69183
Ganab
Name: alpha glucosidase 2 alpha neutral subunit
Synonyms: GluII, G2an
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 14376
VEGA: 19
HGNC: HGNC:4138
Homologene: 5426
Recql5
Name: RecQ protein-like 5
Synonyms: Recql5b, Recq5b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 170472
HGNC: HGNC:9950
Homologene: 31232
Pigk
Name: phosphatidylinositol glycan anchor biosynthesis, class K
Synonyms: 3000001O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 329777
HGNC: HGNC:8965
Homologene: 4002
Nup153
Name: nucleoporin 153
Synonyms: B130015D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218210
HGNC: HGNC:8062
Homologene: 68442
Lrrc4c
Name: leucine rich repeat containing 4C
Synonyms: 6430556C10Rik, netrin g1 ligand, NGL-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241568
Homologene: 18696
Syk
Name: spleen tyrosine kinase
Synonyms: Sykb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 20963
Homologene: 2390
Idh2
Name: isocitrate dehydrogenase 2 (NADP+), mitochondrial
Synonyms: Idh-2, IDPm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 269951
HGNC: HGNC:5383
Homologene: 37590
Mycbpap
Name: MYCBP associated protein
Synonyms: AMAP-1, 4932408B01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 104601
Homologene: 49982
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Pld1
Name: phospholipase D1
Synonyms: Pld1b, Pld1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18805
HGNC: HGNC:9067
Homologene: 116234
Ush2a
Name: usherin
Synonyms: MUSH2A, A930011D15Rik, LOC381317, LOC269160, A930037M10Rik, Ushrn, Ush2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22283
Homologene: 66151
Adgrb3
Name: adhesion G protein-coupled receptor B3
Synonyms: A830096D10Rik, Bai3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 210933
HGNC: HGNC:945
Homologene: 1289
Cldnd1
Name: claudin domain containing 1
Synonyms: 1110019C08Rik, Cldn25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224250
HGNC: HGNC:1322
Homologene: 10534
Dnah3
Name: dynein, axonemal, heavy chain 3
Synonyms: Dnahc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381917
HGNC: HGNC:2949
Homologene: 19674
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241516
Homologene: 110349
Ahnak2
Name: AHNAK nucleoprotein 2
Synonyms: LOC382643
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 100041194
Homologene: 131081
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380698
Homologene: 70869
Vsig8
Name: V-set and immunoglobulin domain containing 8
Synonyms: EG240916
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240916
Homologene: 18616
Insr
Name: insulin receptor
Synonyms: IR, CD220, 4932439J01Rik, D630014A15Rik, IR-B, IR-A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 16337
HGNC: HGNC:6091
Homologene: 20090
Or14j10
Name: olfactory receptor family 14 subfamily J member 10
Synonyms: MOR218-2, GA_x6K02T2PSCP-2084102-2083137, Olfr116
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258625
Ntsr2
Name: neurotensin receptor 2
Synonyms: NTRL, NT2R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 18217
VEGA: 12
HGNC: HGNC:8040
Homologene: 7452
Kcnt1
Name: potassium channel, subfamily T, member 1
Synonyms: slo2, Slack, C030030G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227632
Homologene: 11055
Itgb7
Name: integrin beta 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16421
HGNC: HGNC:6162
Homologene: 20247
Or5p5
Name: olfactory receptor family 5 subfamily P member 5
Synonyms: GA_x6K02T2PBJ9-10144091-10145011, MOR204-33P, Olfr467
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 257919
Homologene: 81542
Ogn
Name: osteoglycin
Synonyms: OG, 3110079A16Rik, mimican, SLRR3A, mimecan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18295
VEGA: 13
HGNC: HGNC:8126
Homologene: 8542
Smcp
Name: sperm mitochondria-associated cysteine-rich protein
Synonyms: Mcsp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 17235
HGNC: HGNC:6962
Ppip5k1
Name: diphosphoinositol pentakisphosphate kinase 1
Synonyms: B430315C20Rik, Hisppd2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 327655
Homologene: 49395
Or9i1b
Name: olfactory receptor family 9 subfamily I member 1B
Synonyms: GA_x6K02T2RE5P-4250267-4251217, MOR211-10_i, MOR211-4P, Olfr1505
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258151
Homologene: 17394
Cntnap5b
Name: contactin associated protein-like 5B
Synonyms: Caspr5-2, C230078M14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241175
Homologene: 104295
Pde6a
Name: phosphodiesterase 6A, cGMP-specific, rod, alpha
Synonyms: Pdea
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225600
HGNC: HGNC:8785
Homologene: 380
Muc3
Name: mucin 3, intestinal
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 666339
Homologene: 141159
Cel
Name: carboxyl ester lipase
Synonyms: BAL, 1810036E18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12613
HGNC: HGNC:1848
Homologene: 37529
Sgip1
Name: SH3-domain GRB2-like (endophilin) interacting protein 1
Synonyms: 3110007P09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 73094
Homologene: 13001
Ggt1
Name: gamma-glutamyltransferase 1
Synonyms: GGT, CD224, Ggtp, dwg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14598
Homologene: 68450
St8sia6
Name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
Synonyms: ST8Sia VI, 1700007J08Rik, Siat8f
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241230
Homologene: 17112
Ceacam14
Name: CEA cell adhesion molecule 14
Synonyms: 1600025E09Rik, 1600021E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67084
HGNC: HGNC:1816
Homologene: 135962
Rxrg
Name: retinoid X receptor gamma
Synonyms: Nr2b3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20183
Homologene: 21373
Usp36
Name: ubiquitin specific peptidase 36
Synonyms: 2700002L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 72344
Homologene: 11828
B9d1
Name: B9 protein domain 1
Synonyms: B9, Eppb9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 27078
Homologene: 8440
Tmem132a
Name: transmembrane protein 132A
Synonyms: 6720481D13Rik, Hspa5bp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 98170
Homologene: 75076
Stk32c
Name: serine/threonine kinase 32C
Synonyms: YANK3, Pkek
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 57740
Homologene: 75157
Or5k8
Name: olfactory receptor family 5 subfamily K member 8
Synonyms: GA_x54KRFPKG5P-55026345-55025418, GA_x54KRFPKG5P-54993816-54992890, MOR184-10P, MOR184-1, Olfr174, Olfr175, Olfr175-ps1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 259004
Homologene: 17461
Stox1
Name: storkhead box 1
Synonyms: 4732470K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216021
Homologene: 17649
Or10d5j
Name: olfactory receptor family 10 subfamily D member 5J
Synonyms: GA_x6K02T2PVTD-33657378-33656440, MOR224-10, Olfr976
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258364
VEGA: 9
Homologene: 64863
Catsper2
Name: cation channel, sperm associated 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 212670
Homologene: 77423
Apon
Name: apolipoprotein N
Synonyms: D10Ucla2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 28194
VEGA: 10
Homologene: 51183
Hpgds
Name: hematopoietic prostaglandin D synthase
Synonyms: H-PGDS, Ptgds2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 54486
Homologene: 113741
Fbxw25
Name: F-box and WD-40 domain protein 25
Synonyms: E330001B16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 546160
Gm21957
Name: predicted gene, 21957
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 25,226,776 bp
  • T to C, chromosome 1 at 71,597,432 bp
  • T to A, chromosome 1 at 100,383,550 bp
  • A to G, chromosome 1 at 167,625,004 bp
  • A to G, chromosome 1 at 172,560,677 bp
  • A to T, chromosome 1 at 188,821,677 bp
  • A to G, chromosome 2 at 13,793,377 bp
  • A to G, chromosome 2 at 25,909,277 bp
  • G to T, chromosome 2 at 25,965,811 bp
  • A to C, chromosome 2 at 28,560,518 bp
  • A to G, chromosome 2 at 76,907,905 bp
  • A to G, chromosome 2 at 82,988,145 bp
  • T to A, chromosome 2 at 97,630,153 bp
  • T to C, chromosome 2 at 121,347,432 bp
  • A to T, chromosome 2 at 121,406,735 bp
  • T to A, chromosome 3 at 28,079,332 bp
  • C to T, chromosome 3 at 92,584,147 bp
  • T to A, chromosome 3 at 152,738,200 bp
  • C to A, chromosome 4 at 102,966,280 bp
  • G to T, chromosome 5 at 137,146,689 bp
  • T to C, chromosome 6 at 65,132,185 bp
  • T to A, chromosome 6 at 83,962,094 bp
  • A to C, chromosome 7 at 3,716,599 bp
  • A to T, chromosome 7 at 17,815,477 bp
  • G to T, chromosome 7 at 30,187,722 bp
  • AGGGCCAG to A, chromosome 7 at 80,098,347 bp
  • T to C, chromosome 7 at 107,814,676 bp
  • T to A, chromosome 7 at 120,021,011 bp
  • C to T, chromosome 7 at 125,219,691 bp
  • T to A, chromosome 7 at 139,119,360 bp
  • G to A, chromosome 8 at 3,202,902 bp
  • A to T, chromosome 9 at 39,956,829 bp
  • A to T, chromosome 9 at 72,477,905 bp
  • T to A, chromosome 9 at 109,663,505 bp
  • G to A, chromosome 10 at 11,170,297 bp
  • G to A, chromosome 10 at 62,664,033 bp
  • A to G, chromosome 10 at 75,585,661 bp
  • A to G, chromosome 10 at 128,255,038 bp
  • T to A, chromosome 11 at 58,996,877 bp
  • A to G, chromosome 11 at 61,506,349 bp
  • A to T, chromosome 11 at 94,503,504 bp
  • A to T, chromosome 11 at 115,927,389 bp
  • A to T, chromosome 11 at 118,265,194 bp
  • T to A, chromosome 12 at 8,744,706 bp
  • C to T, chromosome 12 at 16,659,933 bp
  • A to T, chromosome 12 at 112,779,812 bp
  • G to A, chromosome 13 at 46,717,206 bp
  • A to G, chromosome 13 at 49,609,341 bp
  • A to T, chromosome 13 at 52,631,717 bp
  • G to T, chromosome 13 at 73,648,371 bp
  • T to C, chromosome 14 at 24,454,941 bp
  • A to G, chromosome 14 at 122,476,316 bp
  • A to G, chromosome 15 at 85,391,743 bp
  • A to G, chromosome 15 at 102,231,624 bp
  • T to A, chromosome 16 at 58,729,653 bp
  • G to A, chromosome 16 at 58,824,703 bp
  • T to A, chromosome 16 at 84,857,046 bp
  • A to T, chromosome 17 at 37,624,155 bp
  • G to A, chromosome 17 at 46,386,736 bp
  • G to A, chromosome 18 at 61,232,911 bp
  • T to C, chromosome 19 at 8,908,685 bp
  • G to A, chromosome 19 at 10,864,007 bp
  • A to T, chromosome 19 at 13,919,616 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5323 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
042906-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.