Beutler Mutagenetix

Strain Name:
C57BL/6J-MtgxR5367Btlr/Mmmh
Stock Number:
042945-MU
Citation ID:
RRID:MMRRC_042945-MU
Other Names:
R5367 (G1), C57BL/6J-MtgxR5367Btlr
Major Collection:

Gene Information

Mmp10
Name: matrix metallopeptidase 10
Synonyms: stromelysin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 17384
VEGA: 9
HGNC: HGNC:7156
Homologene: 20546
Slc1a6
Name: solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
Synonyms: EAAT4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 20513
VEGA: 10
Homologene: 21055
Ckap5
Name: cytoskeleton associated protein 5
Synonyms: D730027C18Rik, 3110043H24Rik, 4930432B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 75786
Homologene: 8844
Washc2
Name: WASH complex subunit 2`
Synonyms: Fam21, C530005J20Rik, D6Wsu116e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 28006
Homologene: 41686
Sart3
Name: squamous cell carcinoma antigen recognized by T cells 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 53890
Homologene: 40977
Eif2ak4
Name: eukaryotic translation initiation factor 2 alpha kinase 4
Synonyms: GCN2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 27103
Homologene: 40891
Eif3e
Name: eukaryotic translation initiation factor 3, subunit E
Synonyms: Eif3s6, eIF3-p48, 48kDa, Int6, eIF3-p46
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 16341
VEGA: 15
HGNC: HGNC:3277
Homologene: 1205
Tom1l2
Name: target of myb1-like 2 (chicken)
Synonyms: 2900016I08Rik, A730055F12Rik, myb1-like protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216810
Homologene: 44901
Nap1l4
Name: nucleosome assembly protein 1-like 4
Synonyms: 2810410H14Rik, Nap2, D7Wsu30e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 17955
HGNC: HGNC:7640
Homologene: 133933
Bud31
Name: BUD31 homolog
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231889
Homologene: null
Prom1
Name: prominin 1
Synonyms: Prom-1, 4932416E19Rik, AC133, Prom, CD133
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 19126
HGNC: HGNC:9454
Homologene: 4390
Alkbh5
Name: alkB homolog 5, RNA demethylase
Synonyms: Abh5, Ofoxd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 268420
Homologene: 9818
Myo9a
Name: myosin IXa
Synonyms: C130068I12Rik, 4732465J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 270163
HGNC: HGNC:7608
Homologene: 21371
Gnaz
Name: guanine nucleotide binding protein, alpha z subunit
Synonyms: Gz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 14687
HGNC: HGNC:4395
Homologene: 22574
Erap1
Name: endoplasmic reticulum aminopeptidase 1
Synonyms: Arts1, PILSAP, ERAAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 80898
VEGA: 13
Homologene: 56754
Adam11
Name: a disintegrin and metallopeptidase domain 11
Synonyms: Mdc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 11488
HGNC: HGNC:189
Homologene: 7614
Tmem234
Name: transmembrane protein 234
Synonyms: 2510006D16Rik, 4933407D05Rik, 1500002D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 76799
Homologene: 41314
Fbl
Name: fibrillarin
Synonyms: RNU3IP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 14113
HGNC: HGNC:3599
Homologene: 1099
Slc12a4
Name: solute carrier family 12, member 4
Synonyms: KCC1, K-Cl Co-transporter-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 20498
Homologene: 21056
Cpq
Name: carboxypeptidase Q
Synonyms: 2610034C17Rik, HLS2, 1190003P12Rik, Pgcp, Lal-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 54381
VEGA: 15
Homologene: 9401
Coq10b
Name: coenzyme Q10B
Synonyms: 1500041J02Rik, 9530077A17Rik, 1700030I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 67876
Homologene: 6916
Arap1
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
Synonyms: Centd2, 2410002L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 69710
Homologene: 12326
Ercc8
Name: excision repaiross-complementing rodent repair deficiency, complementation group 8
Synonyms: 2410022P04Rik, Csa, 2810431L23Rik, 4631412O06Rik, Ckn1, B130065P18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 71991
HGNC: HGNC:3439
Homologene: 62
Cblb
Name: Casitas B-lineage lymphoma b
Synonyms: Cbl-b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 208650
VEGA: 16
HGNC: HGNC:1542
Homologene: 15856
Sh2d3c
Name: SH2 domain containing 3C
Synonyms: Nsp3, Shep1, Cas/HEF1-associated signal transducer, Chat, SH2-containing Eph receptor-binding protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 27387
Homologene: 69145
Jag1
Name: jagged 1
Synonyms: Ozz, Serrate-1, Gsfabe2, Htu, ABE2, Headturner
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16449
HGNC: HGNC:6188
Homologene: 180
Pcdh15
Name: protocadherin 15
Synonyms: roda, nmf19, Ush1f, Gm9815
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 11994
Homologene: 23401
Eif4e1b
Name: eukaryotic translation initiation factor 4E family member 1B
Synonyms: Eif4eloo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218268
Homologene: 100945
Nos3
Name: nitric oxide synthase 3, endothelial cell
Synonyms: ecNOS, eNOS, 2310065A03Rik, Nos-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 18127
HGNC: HGNC:7876
Homologene: 504
Piezo2
Name: piezo-type mechanosensitive ion channel component 2
Synonyms: Fam38b, Piezo2, 9030411M15Rik, Fam38b2, 9430028L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 667742
Homologene: 49695
Depdc1a
Name: DEP domain containing 1a
Synonyms: 5830484J08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 76131
Homologene: 9834
Kdm5d
Name: lysine (K)-specific demethylase 5D
Synonyms: Jarid1d, Smcy, HY
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
Alteration at locus: Chemically Induced
NCBI: 20592
Homologene: 55838
Celf5
Name: CUGBP, Elav-like family member 5
Synonyms: Brunol5, 4930565A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 319586
Homologene: 75172
Aadat
Name: aminoadipate aminotransferase
Synonyms: mKat-2, Kyat2, Kat2, KATII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 23923
Homologene: 56540
Ampd3
Name: adenosine monophosphate deaminase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11717
HGNC: HGNC:470
Homologene: 408
Tpo
Name: thyroid peroxidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 22018
Homologene: 461
Mroh2a
Name: maestro heat-like repeat family member 2A
Synonyms: ENSMUSG00000044873, Heatr7b1, OTTMUSG00000020804
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 100040766
Homologene: 85300
Gm10226
Name: predicted gene 10226
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: null
VEGA: null
HGNC: null
Homologene: null
Scara5
Name: scavenger receptor class A, member 5
Synonyms: 4933425F03Rik, 4932433F15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 71145
Homologene: 12556
Ankhd1
Name: ankyrin repeat and KH domain containing 1
Synonyms: 9130019P20Rik, 1110004O12Rik, 4933432B13Rik, A530027J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 108857
Homologene: 87006
Tulp2
Name: tubby-like protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 56734
Homologene: 2492
Grb14
Name: growth factor receptor bound protein 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 50915
HGNC: HGNC:4565
Homologene: 3303
Stox2
Name: storkhead box 2
Synonyms: 4933409N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 71069
Homologene: 18414
Olfr1277
Name: olfactory receptor 1277
Synonyms: GA_x6K02T2Q125-72321818-72320907, MOR248-11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258391
HGNC: null
Homologene: 105176
Gde1
Name: glycerophosphodiester phosphodiesterase 1
Synonyms: 1200003M13Rik, MIR16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 56209
Homologene: 41149
Apol7c
Name: apolipoprotein L 7c
Synonyms: 2210421G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 108956
VEGA: 15
HGNC: null
Homologene: 40940
Smarcal1
Name: SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
Synonyms: Mharp, 6030401P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 54380
Homologene: 8558
Ncln
Name: nicalin
Synonyms: 3100002P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 103425
Homologene: 10604
Arhgef40
Name: Rho guanine nucleotide exchange factor (GEF) 40
Synonyms: E130112L23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 268739
Homologene: 19560
Gm10717
Name: predicted gene 10717
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: null
VEGA: null
HGNC: null
Homologene: null
Krt83
Name: keratin 83
Synonyms: 5430421N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 100126226
HGNC: HGNC:6460
Homologene: 68248
Olfr76
Name: olfactory receptor 76
Synonyms: MOR215-3, GA_x6K02T2RE5P-2479601-2478648, V5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258677
HGNC: HGNC:8319
Homologene: 17342
Aadac
Name: arylacetamide deacetylase
Synonyms: 5033417E09Rik, Aada
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 67758
HGNC: HGNC:17
Homologene: 37436
Smr3a
Name: submaxillary gland androgen regulated protein 3A
Synonyms: MSG1, Smr1, MSG3, Smr3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 20599
Homologene: null
Clec2l
Name: C-type lectin domain family 2, member L
Synonyms: LOC381758
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 665180
VEGA: 6
Homologene: 35527
Scrn2
Name: secernin 2
Synonyms: SES2, D11Moh48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217140
Homologene: 26698
Ankrd55
Name: ankyrin repeat domain 55
Synonyms: C030011J08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 77318
VEGA: 13
Homologene: 12674
Olfr1459
Name: olfactory receptor 1459
Synonyms: MOR202-17, GA_x6K02T2RE5P-3473421-3472498
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258684
HGNC: null
Homologene: 115532
Olfr102
Name: olfactory receptor 102
Synonyms: MOR250-4, GA_x6K02T2PSCP-1775063-1774137
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 258218
HGNC: HGNC:8178
Homologene: 133728
Pdlim7
Name: PDZ and LIM domain 7
Synonyms: 1110003B01Rik, Enigma, 2410002J21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 67399
Homologene: 3980
Bmp4
Name: bone morphogenetic protein 4
Synonyms: Bmp2b1, Bmp2b, Bmp2b-1, Bmp-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 12159
HGNC: HGNC:1071
Homologene: 7247
Tmem35b
Name: transmembrane protein 35B
Synonyms: Zmym6nb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100039968
Homologene: 106612
Cnksr1
Name: connector enhancer of kinase suppressor of Ras 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 194231
Homologene: 4604
Fads2
Name: fatty acid desaturase 2
Synonyms: 2900042M13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 56473
VEGA: 19
HGNC: HGNC:3575
Homologene: 3149
Xbp1
Name: X-box binding protein 1
Synonyms: D11Ertd39e, XBP-1, TREB-5, TREB5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 22433
Homologene: 3722
Rnft1
Name: ring finger protein, transmembrane 1
Synonyms: 0610013E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 76892
Homologene: 41110
Olfr1000
Name: olfactory receptor 1000
Synonyms: GA_x6K02T2Q125-47087719-47086775, MOR175-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 257899
HGNC: null
Homologene: null
Mlf1
Name: myeloid leukemia factor 1
Synonyms: HLS7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 17349
HGNC: HGNC:7125
Homologene: 7839
Gm1988
Name: predicted gene 1988
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 100038967
HGNC: null
Homologene: 80005
Gm6728
Name: predicted gene 6728
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 627022
HGNC: null
Homologene: null
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 55,052,984 bp
  • T to C, chromosome 1 at 72,595,976 bp
  • A to T, chromosome 1 at 88,254,965 bp
  • A to G, chromosome 2 at 32,745,902 bp
  • C to T, chromosome 2 at 64,917,309 bp
  • A to T, chromosome 2 at 85,608,374 bp
  • T to A, chromosome 2 at 91,615,141 bp
  • T to A, chromosome 2 at 111,269,890 bp
  • T to A, chromosome 2 at 118,436,158 bp
  • T to A, chromosome 2 at 137,085,094 bp
  • T to C, chromosome 3 at 60,039,636 bp
  • A to T, chromosome 3 at 67,393,963 bp
  • G to A, chromosome 3 at 159,523,954 bp
  • A to G, chromosome 4 at 127,124,473 bp
  • G to T, chromosome 4 at 129,600,707 bp
  • T to A, chromosome 4 at 134,230,214 bp
  • A to G, chromosome 5 at 24,371,944 bp
  • G to T, chromosome 5 at 44,094,622 bp
  • T to C, chromosome 5 at 88,008,038 bp
  • C to T, chromosome 5 at 113,759,216 bp
  • T to A, chromosome 5 at 145,147,905 bp
  • T to C, chromosome 6 at 38,677,524 bp
  • T to A, chromosome 6 at 116,259,150 bp
  • T to C, chromosome 6 at 136,486,504 bp
  • T to A, chromosome 7 at 28,175,050 bp
  • T to A, chromosome 7 at 39,173,780 bp
  • A to G, chromosome 7 at 45,516,651 bp
  • G to A, chromosome 7 at 101,409,130 bp
  • A to G, chromosome 7 at 110,807,871 bp
  • A to G, chromosome 7 at 118,705,406 bp
  • A to C, chromosome 7 at 143,534,298 bp
  • A to G, chromosome 8 at 47,203,225 bp
  • T to C, chromosome 8 at 60,526,596 bp
  • A to T, chromosome 8 at 105,951,634 bp
  • T to G, chromosome 9 at 3,026,317 bp
  • G to T, chromosome 9 at 7,505,602 bp
  • T to A, chromosome 9 at 59,900,449 bp
  • A to C, chromosome 10 at 74,631,468 bp
  • C to T, chromosome 10 at 74,991,615 bp
  • A to G, chromosome 10 at 78,787,803 bp
  • A to G, chromosome 10 at 81,467,264 bp
  • G to A, chromosome 10 at 81,489,912 bp
  • T to C, chromosome 11 at 5,521,910 bp
  • G to A, chromosome 11 at 60,241,808 bp
  • G to T, chromosome 11 at 60,538,703 bp
  • A to G, chromosome 11 at 86,490,475 bp
  • A to G, chromosome 11 at 97,033,127 bp
  • A to G, chromosome 11 at 102,773,653 bp
  • T to C, chromosome 12 at 30,103,290 bp
  • G to A, chromosome 13 at 54,786,944 bp
  • G to C, chromosome 13 at 55,506,162 bp
  • A to G, chromosome 13 at 74,646,561 bp
  • A to C, chromosome 13 at 108,158,817 bp
  • G to T, chromosome 13 at 112,318,502 bp
  • G to T, chromosome 14 at 46,384,493 bp
  • A to G, chromosome 14 at 51,989,699 bp
  • CG to C, chromosome 14 at 65,759,662 bp
  • T to G, chromosome 15 at 33,213,104 bp
  • C to T, chromosome 15 at 43,252,304 bp
  • C to A, chromosome 15 at 77,526,147 bp
  • A to T, chromosome 15 at 101,486,994 bp
  • T to A, chromosome 16 at 52,204,653 bp
  • T to C, chromosome 17 at 21,691,977 bp
  • T to A, chromosome 17 at 37,314,256 bp
  • T to A, chromosome 18 at 36,589,408 bp
  • T to C, chromosome 18 at 63,064,731 bp
  • A to G, chromosome 19 at 10,064,285 bp
  • A to G, chromosome 19 at 12,120,436 bp
  • G to A, chromosome 19 at 13,146,501 bp
  • G to A, chromosome Y at 941,645 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5367 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042945-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.