Strain Name:
C57BL/6J-MtgxR5369Btlr/Mmmh
Stock Number:
042946-MU
Citation ID:
RRID:MMRRC_042946-MU
Other Names:
R5369 (G1), C57BL/6J-MtgxR5369Btlr
Major Collection:

Gene Information

Galnt10
Name: polypeptide N-acetylgalactosaminyltransferase 10
Synonyms: GalNAc-T10, Galnt9, C330012K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 171212
Homologene: 14924
Sirt3
Name: sirtuin 3
Synonyms: Sir2l3, 2310003L23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 64384
Homologene: 81827
Ints6
Name: integrator complex subunit 6
Synonyms: Notch2l, 2900075H24Rik, DICE1, Ddx26
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 18130
VEGA: 14
Homologene: 8121
Lrp2
Name: low density lipoprotein receptor-related protein 2
Synonyms: Megalin, Gp330, D230004K18Rik, b2b1625.2Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14725
HGNC: HGNC:6694
Homologene: 20952
Cnot7
Name: CCR4-NOT transcription complex, subunit 7
Synonyms: Caf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 18983
Homologene: 49011
Rapgef2
Name: Rap guanine nucleotide exchange factor (GEF) 2
Synonyms: 5830453M24Rik, Pdzgef1, RA-GEF-1, CNRasGEF, nRapGEP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 76089
Homologene: 35477
Ppm1e
Name: protein phosphatase 1E (PP2C domain containing)
Synonyms: PP2CH, POPX1, B930008A12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 320472
Homologene: 22848
Med13l
Name: mediator complex subunit 13-like
Synonyms: 2210413I17Rik, 6330591G05Rik, Trap240L, 9030618F05Rik, Thrap2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 76199
Homologene: 25256
Eif4g3
Name: eukaryotic translation initiation factor 4 gamma, 3
Synonyms: eIF4GII, 1500002J22Rik, 4930523M17Rik, G1-419-52, repro8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230861
HGNC: HGNC:3298
Homologene: 2789
Helb
Name: helicase (DNA) B
Synonyms: D10Ertd664e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 117599
Homologene: 50463
Pkm
Name: pyruvate kinase, muscle
Synonyms: Pk-3, Pk-2, Pk3, Pkm2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 18746
VEGA: 9
HGNC: HGNC:9021
Homologene: 37650
Herc2
Name: HECT and RLD domain containing E3 ubiquitin protein ligase 2
Synonyms: D7H15F32S1, D15F32S1h, D7H15F37S1, rjs, jdf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 15204
HGNC: HGNC:4868
Homologene: 3430
Rsf1
Name: remodeling and spacing factor 1
Synonyms: p325, XAP8, Hbxap, C030033M12Rik, 4832420A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233532
Homologene: 41142
Focad
Name: focadhesin
Synonyms: BC057079
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230393
Homologene: 9842
Zfp292
Name: zinc finger protein 292
Synonyms: Zn-16, Zn-15, Krox-10, Zfp-15, 9430062L07Rik, 5730450D02Rik, Zfp15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 30046
Homologene: 8493
Itpr1
Name: inositol 1,4,5-trisphosphate receptor 1
Synonyms: P400, IP3R1, Itpr-1, Ip3r, Pcp-1, opt, InsP3R type I, Pcp1, wblo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16438
HGNC: HGNC:6180
Homologene: 1673
Smurf1
Name: SMAD specific E3 ubiquitin protein ligase 1
Synonyms: 4930431E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 75788
Homologene: 10712
Git1
Name: GIT ArfGAP 1
Synonyms: p95Cat, Cat-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216963
HGNC: HGNC:4272
Homologene: 32204
Zfp472
Name: zinc finger protein 472
Synonyms: Krim-1B, Krim-1A, Krim-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224691
Homologene: 77422
Abcb8
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 8
Synonyms: 4833412N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74610
HGNC: HGNC:49
Homologene: 5203
Ptprj
Name: protein tyrosine phosphatase, receptor type, J
Synonyms: Byp, DEP-1, Scc-1, Scc1, CD148, RPTPJ
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19271
HGNC: HGNC:9673
Homologene: 2130
Frem1
Name: Fras1 related extracellular matrix protein 1
Synonyms: eyem02Jus, heb, QBRICK, eyes2, crf11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329872
Homologene: 27049
Bod1l
Name: biorientation of chromosomes in cell division 1-like
Synonyms: A230054D04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 665775
Homologene: 45109
Snrnp40
Name: small nuclear ribonucleoprotein 40 (U5)
Synonyms: 0610009C03Rik, Wdr57
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66585
Homologene: 3538
C3
Name: complement component 3
Synonyms: complement factor 3, acylation stimulating protein, Plp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12266
HGNC: HGNC:1318
Homologene: 68031
Ccbe1
Name: collagen and calcium binding EGF domains 1
Synonyms: 9430093N24Rik, 4933426F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 320924
Homologene: 15852
Ostf1
Name: osteoclast stimulating factor 1
Synonyms: SH3P2, C78236, Sh3d3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 20409
HGNC: HGNC:8510
Homologene: 8227
Celf2
Name: CUGBP, Elav-like family member 2
Synonyms: Napor-2, ETR-3, B230345P09Rik, Cugbp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14007
HGNC: HGNC:2550
Homologene: 4783
Snx9
Name: sorting nexin 9
Synonyms: SH3PX1, SDP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 66616
VEGA: 17
Homologene: 49454
Cfap97
Name: cilia and flagella associated protein 97
Synonyms: 1110068E21Rik, 4933411K20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 66756
Homologene: 12026
Mrps18a
Name: mitochondrial ribosomal protein S18A
Synonyms: 1110004O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 68565
Homologene: 32391
Acbd5
Name: acyl-Coenzyme A binding domain containing 5
Synonyms: 1300014E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74159
Homologene: 12541
Rbm45
Name: RNA binding motif protein 45
Synonyms: Drb1, G430095G15Rik, Drbp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241490
Homologene: 15560
Eml5
Name: echinoderm microtubule associated protein like 5
Synonyms: C130068M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 319670
VEGA: 12
Homologene: 26807
Fnip1
Name: folliculin interacting protein 1
Synonyms: A730024A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216742
Homologene: 28173
Colec12
Name: collectin sub-family member 12
Synonyms: SRCL, CL-P1, Scara4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 140792
VEGA: 18
Homologene: 34248
Soga1
Name: suppressor of glucose, autophagy associated 1
Synonyms: D430036N24Rik, 9830001H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 320706
Homologene: 52382
Ccr1
Name: chemokine (C-C motif) receptor 1
Synonyms: Cmkbr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12768
VEGA: 9
HGNC: HGNC:1602
Homologene: 20344
Nlrp1b
Name: NLR family, pyrin domain containing 1B
Synonyms: Nalp1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 637515
Homologene: 19080
Pcsk5
Name: proprotein convertase subtilisin/kexin type 5
Synonyms: PC6, SPC6, PC5A, PC5/6A, b2b585Clo, b2b1549Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18552
VEGA: 19
HGNC: HGNC:8747
Homologene: 21244
Btnl6
Name: butyrophilin-like 6
Synonyms: NG13, Gm6519
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 624681
Homologene: 106849
BC024139
Name: cDNA sequence BC024139
Synonyms: 6230424I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 271278
Homologene: 129974
Col5a2
Name: collagen, type V, alpha 2
Synonyms: 1110014L14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12832
HGNC: HGNC:2210
Homologene: 20119
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Slc24a2
Name: solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
Synonyms: 6330417K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 76376
Homologene: 10669
Krt6a
Name: keratin 6A
Synonyms: mK6[a], MK6a, Krt2-6c, Krt2-6a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16687
VEGA: 15
Homologene: 136794
Scara5
Name: scavenger receptor class A, member 5
Synonyms: 4932433F15Rik, 4933425F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 71145
Homologene: 12556
F12
Name: coagulation factor XII (Hageman factor)
Synonyms: FXII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 58992
HGNC: HGNC:3530
Homologene: 425
A2ml1
Name: alpha-2-macroglobulin like 1
Synonyms: Ovos2, BC048546
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232400
Homologene: 45969
Htra4
Name: HtrA serine peptidase 4
Synonyms: B430206E18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 330723
Homologene: 17801
Nat8f2
Name: N-acetyltransferase 8 (GCN5-related) family member 2
Synonyms: Cml2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 93673
Grb14
Name: growth factor receptor bound protein 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 50915
HGNC: HGNC:4565
Homologene: 3303
Fam227a
Name: family with sequence similarity 227, member A
Synonyms: 4933432B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 75729
Homologene: 123434
B3galnt2
Name: UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 2
Synonyms: A930105D20Rik, D230016N13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 97884
VEGA: 13
Homologene: 17595
Map3k6
Name: mitogen-activated protein kinase kinase kinase 6
Synonyms: Ask2, MEKK6, MAPKKK6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 53608
HGNC: HGNC:6858
Homologene: 3435
Npc1l1
Name: NPC1 like intracellular cholesterol transporter 1
Synonyms: Niemann-Pick disease, type C1, 9130221N23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237636
HGNC: HGNC:7898
Homologene: 56585
Lrrc15
Name: leucine rich repeat containing 15
Synonyms: 5430427N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 74488
Homologene: 26080
Clcn4
Name: chloride channel, voltage-sensitive 4
Synonyms: Clc4-2, Clcn4-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12727
HGNC: HGNC:2022
Homologene: 68207
Asb15
Name: ankyrin repeat and SOCS box-containing 15
Synonyms: 4930400E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 78910
Homologene: 43797
Olfr202
Name: olfactory receptor 202
Synonyms: GA_x54KRFPKG5P-55498766-55497843, MOR182-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 258997
Homologene: 138323
Slc43a3
Name: solute carrier family 43, member 3
Synonyms: SEEEG-1, Eeg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 58207
Homologene: 40925
Vmn1r201
Name: vomeronasal 1 receptor 201
Synonyms: V1ri4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 171255
Homologene: 110880
Ttbk2
Name: tau tubulin kinase 2
Synonyms: TTK, B930008N24Rik, 2610507N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 140810
Homologene: 62795
Scel
Name: sciellin
Synonyms: 9230114I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 64929
VEGA: 14
Homologene: 2850
Dip2a
Name: disco interacting protein 2 homolog A
Synonyms: Kiaa0184-hp, 4931420H10Rik, Dip2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 64451
Homologene: 41012
Pde4c
Name: phosphodiesterase 4C, cAMP specific
Synonyms: dunce, Dpde1, E130301F19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 110385
HGNC: HGNC:8782
Homologene: 20256
2210010C04Rik
Name: RIKEN cDNA 2210010C04 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 67373
Homologene: 134055
Map3k9
Name: mitogen-activated protein kinase kinase kinase 9
Synonyms: Mlk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 338372
VEGA: 12
HGNC: HGNC:6861
Homologene: 76377
Vmn1r1
Name: vomeronasal 1 receptor 1
Synonyms: Gm6628
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 625823
Homologene: 83459
Gstm5
Name: glutathione S-transferase, mu 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 14866
HGNC: HGNC:4635
Homologene: 658
Ifi209
Name: interferon activated gene 209
Synonyms: Ifix, Pyhin1, Pyhin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 236312
HGNC: HGNC:5395
Homologene: 115929
Serpinb5
Name: serine (or cysteine) peptidase inhibitor, clade B, member 5
Synonyms: Maspin, Spi7, ovalbumin, 1110036M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20724
HGNC: HGNC:8949
Homologene: 20580
A330070K13Rik
Name: RIKEN cDNA A330070K13 gene
Synonyms: LOC381673
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381673
Cd27
Name: CD27 antigen
Synonyms: Cd27, S152, Tp55, Tnfrsf7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 21940
Homologene: 74386
Olfr419
Name: olfactory receptor 419
Synonyms: GA_x6K02T2P20D-20891507-20892448, MOR267-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 258710
Homologene: 72017
Gm6866
Name: predicted gene 6866
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 628304
Homologene: 80005
Gm7935
Name: predicted pseudogene 7935
Synonyms: Sf3b4_ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 666113
VEGA: 15
Gm6185
Name: predicted gene 6185
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 620839
Snrnp35
Name: small nuclear ribonucleoprotein 35 (U11/U12)
Synonyms: 6330548G22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 76167
Homologene: 31415
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 45,421,230 bp
  • A to T, chromosome 1 at 106,881,757 bp
  • A to T, chromosome 1 at 161,209,760 bp
  • T to C, chromosome 1 at 173,637,307 bp
  • A to G, chromosome 1 at 174,250,441 bp
  • A to G, chromosome 1 at 182,157,776 bp
  • C to A, chromosome 2 at 7,081,081 bp
  • T to A, chromosome 2 at 23,112,510 bp
  • G to T, chromosome 2 at 41,004,613 bp
  • C to T, chromosome 2 at 64,917,309 bp
  • T to C, chromosome 2 at 69,459,560 bp
  • T to A, chromosome 2 at 76,370,250 bp
  • A to T, chromosome 2 at 84,957,723 bp
  • T to C, chromosome 2 at 90,469,641 bp
  • T to C, chromosome 2 at 120,825,262 bp
  • T to C, chromosome 2 at 157,040,734 bp
  • A to T, chromosome 3 at 79,069,432 bp
  • G to A, chromosome 3 at 107,898,466 bp
  • G to A, chromosome 4 at 34,807,491 bp
  • A to G, chromosome 4 at 83,001,739 bp
  • C to T, chromosome 4 at 86,991,388 bp
  • T to A, chromosome 4 at 88,121,373 bp
  • T to C, chromosome 4 at 130,362,646 bp
  • T to C, chromosome 4 at 133,247,681 bp
  • C to T, chromosome 4 at 138,183,334 bp
  • C to T, chromosome 5 at 24,400,139 bp
  • A to G, chromosome 5 at 41,827,183 bp
  • T to A, chromosome 5 at 118,724,010 bp
  • A to G, chromosome 5 at 124,490,199 bp
  • G to A, chromosome 5 at 130,379,091 bp
  • G to A, chromosome 5 at 144,883,655 bp
  • T to C, chromosome 6 at 24,562,564 bp
  • T to A, chromosome 6 at 41,033,006 bp
  • G to T, chromosome 6 at 85,867,872 bp
  • T to A, chromosome 6 at 108,519,424 bp
  • T to A, chromosome 6 at 125,234,364 bp
  • T to C, chromosome 6 at 128,568,833 bp
  • T to A, chromosome 7 at 7,296,033 bp
  • A to T, chromosome 7 at 41,218,211 bp
  • T to A, chromosome 7 at 56,182,700 bp
  • ATGGCG to ATGGCGACGGTGGCG, chromosome 7 at 97,579,904 bp
  • A to T, chromosome 7 at 140,869,493 bp
  • T to G, chromosome 8 at 25,033,569 bp
  • A to T, chromosome 8 at 40,494,020 bp
  • A to G, chromosome 8 at 46,169,650 bp
  • T to C, chromosome 8 at 70,750,105 bp
  • A to T, chromosome 9 at 59,670,634 bp
  • A to T, chromosome 9 at 123,964,289 bp
  • A to G, chromosome 10 at 76,292,360 bp
  • T to C, chromosome 10 at 93,061,257 bp
  • T to C, chromosome 10 at 120,089,702 bp
  • A to G, chromosome 11 at 6,217,705 bp
  • T to C, chromosome 11 at 54,502,589 bp
  • T to G, chromosome 11 at 57,765,747 bp
  • A to G, chromosome 11 at 71,181,799 bp
  • G to T, chromosome 11 at 77,503,027 bp
  • A to G, chromosome 11 at 87,249,050 bp
  • T to A, chromosome 12 at 81,722,052 bp
  • C to T, chromosome 12 at 98,858,783 bp
  • T to C, chromosome 13 at 13,994,425 bp
  • T to A, chromosome 13 at 22,475,502 bp
  • T to C, chromosome 13 at 55,418,491 bp
  • T to C, chromosome 14 at 62,743,935 bp
  • CG to C, chromosome 14 at 65,759,662 bp
  • A to T, chromosome 14 at 103,586,493 bp
  • A to T, chromosome 15 at 74,081,114 bp
  • A to C, chromosome 15 at 76,120,222 bp
  • A to T, chromosome 15 at 79,615,436 bp
  • T to A, chromosome 15 at 101,692,558 bp
  • A to T, chromosome 16 at 30,272,904 bp
  • A to T, chromosome 16 at 59,284,380 bp
  • T to A, chromosome 17 at 5,920,580 bp
  • A to T, chromosome 17 at 32,977,743 bp
  • T to A, chromosome 17 at 34,507,985 bp
  • T to C, chromosome 17 at 46,125,626 bp
  • C to A, chromosome 17 at 57,221,159 bp
  • A to G, chromosome 18 at 9,866,750 bp
  • G to A, chromosome 18 at 66,061,414 bp
  • A to G, chromosome 19 at 17,581,255 bp
  • C to T, chromosome 19 at 18,581,325 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5369 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042946-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.