Strain Name:
C57BL/6J-MtgxR5373Btlr/Mmmh
Stock Number:
042949-MU
Citation ID:
RRID:MMRRC_042949-MU
Other Names:
R5373 (G1), C57BL/6J-MtgxR5373Btlr
Major Collection:

Gene Information

Cntnap2
Name: contactin associated protein-like 2
Synonyms: 5430425M22Rik, Caspr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 66797
Homologene: 69159
Ptprz1
Name: protein tyrosine phosphatase, receptor type Z, polypeptide 1
Synonyms: PTPbeta, DSD-1-PG, Ptprz, Ptpz, Rptpbeta, PTPzeta, RPTPz, phosphacan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 19283
HGNC: HGNC:9685
Homologene: 2136
Fezf2
Name: Fez family zinc finger 2
Synonyms: Zfp312, Fezl, Fez, forebrain embryonic zinc finger
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 54713
VEGA: 14
Homologene: 9957
D630045J12Rik
Name: RIKEN cDNA D630045J12 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 330286
Homologene: 19782
Arpp21
Name: cyclic AMP-regulated phosphoprotein, 21
Synonyms: R3hdm3, 0710001E13Rik, D9Bwg1012e, Tarpp, ARPP-21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 74100
Homologene: 32306
Ptpn14
Name: protein tyrosine phosphatase, non-receptor type 14
Synonyms: PTP36, C130080N23Rik, OTTMUSG00000022087
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 19250
HGNC: HGNC:9647
Homologene: 3941
Ptprf
Name: protein tyrosine phosphatase, receptor type, F
Synonyms: RPTP-LAR, LAR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 19268
HGNC: HGNC:9670
Homologene: 20623
Med1
Name: mediator complex subunit 1
Synonyms: CRSP210, Pparbp, TRAP220, DRIP205, PBP, l11Jus15, TRAP 220
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 19014
HGNC: HGNC:9234
Homologene: 21002
Snx6
Name: sorting nexin 6
Synonyms: 2010006G21Rik, 2610032J07Rik, 2810425K19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 72183
VEGA: 12
Homologene: 12304
Ptprg
Name: protein tyrosine phosphatase, receptor type, G
Synonyms: RPTPgamma, 5430405N12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 19270
HGNC: HGNC:9671
Homologene: 2129
Epb41l3
Name: erythrocyte membrane protein band 4.1 like 3
Synonyms: NBL3, Epb4.1l3, 4.1B, DAL1P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 13823
HGNC: HGNC:3380
Homologene: 49308
Pik3c3
Name: phosphatidylinositol 3-kinase catalytic subunit type 3
Synonyms: Vps34, 5330434F23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225326
HGNC: HGNC:8974
Homologene: 1986
Ank3
Name: ankyrin 3, epithelial
Synonyms: Ank-3, AnkG, Ankyrin-G, Ankyrin-3, 2900054D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 11735
HGNC: HGNC:494
Homologene: 56908
Dtna
Name: dystrobrevin alpha
Synonyms: a-DB-1, 87K protein, 2210407P21Rik, alpha-dystrobrevin, A0, adbn, Dtn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 13527
VEGA: 18
HGNC: HGNC:3057
Homologene: 20362
Cisd2
Name: CDGSH iron sulfur domain 2
Synonyms: 1500031D15Rik, Zcd2, 1500026J14Rik, B630006A20Rik, 1500009M05Rik, Miner1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 67006
Homologene: 36436
Anapc7
Name: anaphase promoting complex subunit 7
Synonyms: APC7, prediabetic NOD sera-reactive autoantigen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 56317
Homologene: 10512
St7
Name: suppression of tumorigenicity 7
Synonyms: Fam4a2, TSG7, SEN4, HELG, 9430001H04Rik, RAY1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 64213
Homologene: 10185
Dmxl2
Name: Dmx-like 2
Synonyms: E130119P06Rik, 6430411K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235380
HGNC: HGNC:2938
Homologene: 41022
Adss
Name: adenylosuccinate synthetase, non muscle
Synonyms: AS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 11566
HGNC: HGNC:292
Homologene: 875
Dusp3
Name: dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)
Synonyms: VHR, 2210015O03Rik, T-DSP11, 5031436O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 72349
HGNC: HGNC:3069
Homologene: 20870
Cspp1
Name: centrosome and spindle pole associated protein 1
Synonyms: 2310020J12Rik, 4930413O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 211660
Homologene: 23487
Camkv
Name: CaM kinase-like vesicle-associated
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235604
Homologene: 56983
Chsy1
Name: chondroitin sulfate synthase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 269941
Homologene: 8950
Fcrl5
Name: Fc receptor-like 5
Synonyms: mBXMH2, Fcrh3, BXMAS1-like protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 329693
Homologene: 137404
Mtfr2
Name: mitochondrial fission regulator 2
Synonyms: Fam54a, 2610016C23Rik, 4933412C16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 71804
VEGA: 10
Homologene: 69441
Eml2
Name: echinoderm microtubule associated protein like 2
Synonyms: 1600029N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 72205
Homologene: 8125
Ccdc88a
Name: coiled coil domain containing 88A
Synonyms: D130005J21Rik, GIV, A430106J12Rik, C330012F17Rik, Girdin, HkRP1, C130096N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 108686
Homologene: 41180
Fam169b
Name: family with sequence similarity 169, member B
Synonyms: EG434197
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 434197
Homologene: 79038
Dnajc6
Name: DnaJ heat shock protein family (Hsp40) member C6
Synonyms: 2810027M23Rik, auxilin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 72685
Homologene: 8865
Pla2g4e
Name: phospholipase A2, group IVE
Synonyms: 2310026J01Rik, Pla2epsilon
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 329502
Homologene: 65339
Lig1
Name: ligase I, DNA, ATP-dependent
Synonyms: LigI, mLigI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 16881
HGNC: HGNC:6598
Homologene: 197
Dpysl3
Name: dihydropyrimidinase-like 3
Synonyms: Ulip1, TUC4, CRMP-4, Ulip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 22240
HGNC: HGNC:3015
Homologene: 20361
Kdm5d
Name: lysine (K)-specific demethylase 5D
Synonyms: Jarid1d, Smcy, HY
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
Alteration at locus: Chemically Induced
NCBI: 20592
Homologene: 55838
Evc2
Name: EvC ciliary complex subunit 2
Synonyms: Ellis van Creveld syndrome 2, limbin, Lbn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 68525
Homologene: 17117
Cplane1
Name: ciliogenesis and planar polarity effector 1
Synonyms: Hug, Jbts17, b2b012Clo, 2410089E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 73692
Homologene: 11315
Snrk
Name: SNF related kinase
Synonyms: SNRK, 2010012F07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 20623
Homologene: 9797
1110002E22Rik
Name: RIKEN cDNA 1110002E22 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 102634333
Homologene: 131709
Dlgap2
Name: DLG associated protein 2
Synonyms: DAP2, SAP90/PSD-95-associated protein 2, 6430596N04Rik, PSD-95/SAP90-binding protein 2, Sapap2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244310
HGNC: HGNC:2906
Homologene: 3484
Serpina3j
Name: serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3J
Synonyms: Gm4931, alpha-1 antiproteinase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 238395
HGNC: HGNC:16
Homologene: 120222
Eif3m
Name: eukaryotic translation initiation factor 3, subunit M
Synonyms: Pcid1, Ga17, Tango7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 98221
Homologene: 4639
Cdh12
Name: cadherin 12
Synonyms: Br-cadherin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 215654
HGNC: HGNC:1751
Homologene: 37873
Spata6
Name: spermatogenesis associated 6
Synonyms: Hash, 1700062C23Rik, KRP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 67946
Homologene: 10410
Ly75
Name: lymphocyte antigen 75
Synonyms: CD205, DEC-205
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17076
HGNC: HGNC:6729
Homologene: 31085
Corin
Name: corin, serine peptidase
Synonyms: Lrp4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 53419
Homologene: 4804
Abcb5
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 5
Synonyms: 9230106F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 77706
HGNC: HGNC:46
Homologene: 83488
Rufy4
Name: RUN and FYVE domain containing 4
Synonyms: F930048N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 435626
Homologene: 52359
Mpo
Name: myeloperoxidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17523
HGNC: HGNC:7218
Homologene: 55450
Psd2
Name: pleckstrin and Sec7 domain containing 2
Synonyms: 6330404E20Rik, EFA6C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 74002
Homologene: 12522
Thap2
Name: THAP domain containing, apoptosis associated protein 2
Synonyms: 9030625G08Rik, 2900040O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 66816
VEGA: 10
Homologene: 12039
Tnrc18
Name: trinucleotide repeat containing 18
Synonyms: Zfp469, EG381742
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231861
Homologene: 45603
Zfp518a
Name: zinc finger protein 518A
Synonyms: 2810401C22Rik, Zfp518, 6330417C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 72672
VEGA: 19
Homologene: 19378
Zup1
Name: zinc finger containing ubiquitin peptidase 1
Synonyms: 2700019D07Rik, Zufsp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 72580
VEGA: 10
Homologene: 12472
Rgsl1
Name: regulator of G-protein signaling like 1
Synonyms: 4930415K13Rik, Rgsl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 240816
Homologene: 129962
Rxfp2
Name: relaxin/insulin-like family peptide receptor 2
Synonyms: Great, Gpr106, LGR8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 140498
Homologene: 15402
Zfp85
Name: zinc finger protein 85
Synonyms: Zfp71, Zfp85-rs1, KRAB19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 22746
Homologene: 133709
Slc26a7
Name: solute carrier family 26, member 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 208890
Homologene: 13770
Adgrf1
Name: adhesion G protein-coupled receptor F1
Synonyms: Gpr110, 5031409J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 77596
Homologene: 124643
Susd5
Name: sushi domain containing 5
Synonyms: LOC382111
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 382111
VEGA: 9
Homologene: 19526
Stap1
Name: signal transducing adaptor family member 1
Synonyms: STAP-1, Brdg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 56792
Homologene: 8103
Plch1
Name: phospholipase C, eta 1
Synonyms: Plcl3, PLCeta1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 269437
Homologene: 88833
Zc3h6
Name: zinc finger CCCH type containing 6
Synonyms: 4833425H18Rik, 4631426G04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 78751
Homologene: 35328
Vmn1r85
Name: vomeronasal 1 receptor 85
Synonyms: V1rj3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 252909
Homologene: 74338
Nt5c
Name: 5',3'-nucleotidase, cytosolic
Synonyms: Dnt, Dnt1, Umph-2, Umph2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 50773
Homologene: 8745
Ptgs1
Name: prostaglandin-endoperoxide synthase 1
Synonyms: Pghs1, Cox-1, cyclooxygenase 1, Cox-3, COX1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 19224
HGNC: HGNC:9604
Homologene: 743
Vmn2r71
Name: vomeronasal 2, receptor 71
Synonyms: EG233445
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233445
Homologene: 115466
Ugt1a10
Name: UDP glycosyltransferase 1 family, polypeptide A10
Synonyms: A13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 394430
Homologene: 133281
Mn1
Name: meningioma 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 433938
HGNC: HGNC:7180
Homologene: 37620
Kcnq5
Name: potassium voltage-gated channel, subfamily Q, member 5
Synonyms: 9230107O05Rik, D1Mgi1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226922
HGNC: HGNC:6299
Homologene: 28270
Cwc15
Name: CWC15 spliceosome-associated protein
Synonyms: 0610040D20Rik, 2900052N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 66070
Homologene: 9499
Pcdhga4
Name: protocadherin gamma subfamily A, 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 93712
HGNC: HGNC:8702
Homologene: 81866
Ighv3-5
Name: immunoglobulin heavy variable 3-5
Synonyms: Gm7112
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 633457
Slirp
Name: SRA stem-loop interacting RNA binding protein
Synonyms: 1810035L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 380773
Homologene: 12825
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to G, chromosome 1 at 10,134,126 bp
  • T to A, chromosome 1 at 21,961,571 bp
  • T to C, chromosome 1 at 74,147,663 bp
  • T to A, chromosome 1 at 88,055,910 bp
  • C to T, chromosome 1 at 153,790,307 bp
  • T to G, chromosome 1 at 177,796,388 bp
  • T to C, chromosome 1 at 189,850,963 bp
  • A to T, chromosome 2 at 36,251,186 bp
  • A to T, chromosome 2 at 60,311,771 bp
  • A to T, chromosome 2 at 105,012,932 bp
  • A to T, chromosome 2 at 120,186,395 bp
  • A to T, chromosome 2 at 129,002,156 bp
  • A to C, chromosome 3 at 63,698,078 bp
  • A to G, chromosome 3 at 87,446,391 bp
  • A to G, chromosome 3 at 135,408,835 bp
  • A to G, chromosome 3 at 138,067,635 bp
  • A to T, chromosome 4 at 14,546,447 bp
  • T to C, chromosome 4 at 101,615,627 bp
  • T to A, chromosome 4 at 111,822,834 bp
  • G to T, chromosome 4 at 118,226,041 bp
  • C to T, chromosome 5 at 37,378,210 bp
  • A to T, chromosome 5 at 72,304,953 bp
  • A to G, chromosome 5 at 86,090,928 bp
  • A to G, chromosome 5 at 111,421,886 bp
  • T to A, chromosome 5 at 122,438,217 bp
  • G to A, chromosome 5 at 142,740,156 bp
  • A to G, chromosome 5 at 150,070,260 bp
  • T to C, chromosome 6 at 17,834,724 bp
  • T to A, chromosome 6 at 23,007,355 bp
  • T to C, chromosome 6 at 38,174,251 bp
  • T to A, chromosome 6 at 47,107,969 bp
  • A to T, chromosome 7 at 13,084,328 bp
  • AG to A, chromosome 7 at 13,305,923 bp
  • A to T, chromosome 7 at 19,179,263 bp
  • C to T, chromosome 7 at 66,110,076 bp
  • T to C, chromosome 7 at 68,300,838 bp
  • C to T, chromosome 7 at 85,618,542 bp
  • A to G, chromosome 8 at 14,823,614 bp
  • A to G, chromosome 9 at 14,504,938 bp
  • A to G, chromosome 9 at 54,369,189 bp
  • T to C, chromosome 9 at 107,946,889 bp
  • T to G, chromosome 9 at 112,067,268 bp
  • G to A, chromosome 9 at 114,082,585 bp
  • G to C, chromosome 9 at 122,166,320 bp
  • G to T, chromosome 10 at 20,352,852 bp
  • T to C, chromosome 10 at 33,927,466 bp
  • A to G, chromosome 10 at 69,953,476 bp
  • A to T, chromosome 10 at 115,372,839 bp
  • C to T, chromosome 11 at 29,463,409 bp
  • T to C, chromosome 11 at 87,803,611 bp
  • T to A, chromosome 11 at 98,163,963 bp
  • A to G, chromosome 11 at 101,984,625 bp
  • G to A, chromosome 11 at 115,490,817 bp
  • T to C, chromosome 12 at 54,770,728 bp
  • T to C, chromosome 12 at 87,449,422 bp
  • A to G, chromosome 12 at 104,314,727 bp
  • A to G, chromosome 12 at 114,262,953 bp
  • G to T, chromosome 12 at 118,887,177 bp
  • T to C, chromosome 13 at 67,749,458 bp
  • A to G, chromosome 14 at 12,213,665 bp
  • A to T, chromosome 14 at 12,344,803 bp
  • T to C, chromosome 15 at 8,270,803 bp
  • A to C, chromosome 15 at 21,583,912 bp
  • G to A, chromosome 17 at 43,291,005 bp
  • C to A, chromosome 17 at 69,286,800 bp
  • T to C, chromosome 18 at 23,651,613 bp
  • T to C, chromosome 18 at 30,312,561 bp
  • T to A, chromosome 18 at 36,007,503 bp
  • T to C, chromosome 18 at 37,685,596 bp
  • T to C, chromosome 18 at 43,361,036 bp
  • T to C, chromosome 19 at 40,913,510 bp
  • C to T, chromosome Y at 927,995 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5373 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042949-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.